The contribution of diet and genotype to iron status in women: A classical twin study

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Fairweather Tait, Susan J ^a   Guile, Geoffrey R ^a   Valdes, Ana M ^b   Wawer, Anna A ^a   Hurst, Rachel ^a   Skinner, Jane ^a   Macgregor, Alexander J ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; C REACTIVE PROTEIN; CYTOCHROME REDUCTASE; FERRITIN; TRANSFERRIN RECEPTOR;

ADULT; AGED; ARTICLE; BODY MASS; CALCIUM INTAKE; DIET; ENZYME IMMUNOASSAY; FERRITIN BLOOD LEVEL; FOOD FREQUENCY QUESTIONNAIRE; FOOD INTAKE; GENETIC VARIABILITY; HUMAN; HUMAN EXPERIMENT; IRON BALANCE; MIDDLE AGED; NORMAL HUMAN; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BLOOD LEVEL; SINGLE NUCLEOTIDE POLYMORPHISM; TWINS; VITAMIN INTAKE; WOMEN'S HEALTH;

ADULT; CALCIUM, DIETARY; CYTOCHROME B GROUP; DIET; FEMALE; FERRITINS; GENETIC MARKERS; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IRON; MEMBRANE PROTEINS; MIDDLE AGED; OXIDOREDUCTASES; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, TRANSFERRIN; SOLUBILITY; TRANSFERRIN; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 84896696808     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083047     Document Type: Article

References (20)

1. Feder JN, Gnirke A, Thomas W, Tsuchihaschi Z, Ruddy DA, et al. (1996) A novel MHC class-1-like gene is mutated in patients with hereditary haemochromatosis. Nat Gene 13: 399-408. (Pubitemid 26256612)
2. Hurrell R, Egli I (2010) Iron bioavailability and dietary reference values. Am J Clin Nutr 91: 1461S-1467S.
3. Visscher OM (2004) Power of the classical twin design revisited. Twin Res 7: 505-512.
4. Bingham SA, Welch AA, McTaggart A, Mulligan AA, Runswick SA, et al. (2001) Nutritional Methods in the European Prospective Investigation of Cancer in Norfolk. Pub Health Nutr 4: 847-858. (Pubitemid 32566539)
5. Teucher B, Skinner J, Skidmore PM, Cassidy A, Fairweather-Tait SJ, et al. (2007) Dietary patterns and heritability of food choice in a UK female twin cohort. Twin Res Hum Gen 10: 734-748. (Pubitemid 47608008)
6. Thorpe SJ, Heath A, Sharp G, Cook J, Ellis R, et al. (2010) A WHO reference reagent for the Serum Transferrin Receptor (sTfR): international collaborative study to evaluate a recombinant soluble transferrin receptor preparation. Clin Chem Lab Med 48: 815-820.
7. Cook JD, Flowers CH, Skikne BS (2003) The quantitative assessment of body iron. Blood 101: 3359-3363.
8. Almasy L, Blangero J (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Gen 62: 1198-1211. (Pubitemid 28199022)
9. Whitfield JB, Cullen LM, Jazwinska EC, Powell LW, Heath AC, et al. (2000) Effects of HFE C282Y and H63D polymorphisms and polygenic background on iron stores in a large community sample of twins. Am J Hum Gen 66: 1246-1258. (Pubitemid 30468782)
10. McLaren CE, Garner CP, Constantine CC, McLachlan S, Vulpe CD, et al. (2011) Genome-wide association study identifies genetic loci associated with iron deficiency. PLoS ONE 6: e17390.
11. Benyamin B, McRae A, Zhu G, Gordon S, Henders AK, et al. (2009) Variants in TF and HFE explain ∼40% of genetic variation in serum-transferrin levels. Am J Hum Gen 84: 60-65.
12. Oexle K, Ried JS, Hicks AA, Tanaka T, Hayward C, et al. (2011) Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels. Hum Mol Gen 20: 1042-1047.
13. Minihane AM, Fairweather-Tait SJ (1998) Effect of calcium supplementation on daily nonheme-iron absorption and long-term iron status. Am J Clin Nutr 68: 96-102. (Pubitemid 28307660)
14. Lonnerdal B (2010) Calcium and iron absorption - mechanisms and public health relevance. Int J Vit Nutr Res 80: 293-299.
15. Hallberg L, Brune M, Erlandsson M, Sandberg AS, Rossander-Hulten L. (1991) Calcium: effect of different amounts on nonheme- and heme-iron absorption in humans. Am J Clin Nutr 53: 112-119. (Pubitemid 21917618)
16. Gaitán D, Flores S, Saavedra P, Miranda C, Olivares M, et al. (2011) Calcium does not inhibit the absorption of 5 milligrams of nonheme or heme iron at doses less than 800 milligrams in nonpregnant women. J Nutr. 141: 1652-1656.
17. Thompson BA, Sharp PA, Elliott R, Fairweather-Tait SJ (2010) Inhibitory effect of calcium on non-heme iron absorption may be related to translocation of DMT-1 at the apical membrane of enterocytes. J Agric Food Chem 58: 8414-8417.
18. Whitfield JB, Treloar S, Zhu G, Powell LW, Martin NG (2003) Relative importance of female-specific and non-female-specific effects on variation in iron stores between women. Br J Haem 120: 860-866. (Pubitemid 36315112)
19. Harvey LJ, Armah CN, Dainty JR, Foxall RJ, Lewis JD, et al. (2005) Impact of menstrual blood loss and diet on iron deficiency among women in the UK. Br J Nutr 94: 557-564. (Pubitemid 41555497)
20. Rybo G, Hallberg L (1966) Influence of heredity and environment on normal menstrual blood loss. Acta Obstet Gynecol Scand 45: 389-410.