Ruthmycin, a new Tetracyclic Polyketide from Streptomyces sp. RM-4-15

Organic Letters

Volumn 16, Issue 2, 2014, Pages 456-459

  Wang, Xiachang ^a   Elshahawi, Sherif I ^a   Shaaban, Khaled A ^a   Fang, Lei ^a   Ponomareva, Larissa V ^a   Zhang, Yinan ^a   Copley, Gregory C ^b   Hower, James C ^b   Zhan, Chang Guo ^a   Kharel, Madan K ^c   Thorson, Jon S ^a  

^a University of Kentucky   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF MARYLAND EASTERN SHORE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; FRENOLICIN B; NAPHTHOQUINONE; POLYKETIDE; RUTHMYCIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES; UNITED STATES;

ANTIFUNGAL AGENTS; KENTUCKY; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NAPHTHOQUINONES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLYKETIDES; STREPTOMYCES;

EID: 84896693216     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol4033418     Document Type: Article

References (20)

1. Brimble, M. A.; Duncalf, L. J.; Nairn, M. R. Nat. Prod. Rep. 1999, 16, 267-281.
2. Ellestad, G. A.; Kunstmann, M. P.; Whaley, H. A.; Patterson, E. L. J. Am. Chem. Soc. 1968, 90, 1325-1332.
3. Iwai, Y.; Kora, A.; Takahashi, Y.; Hayashi, T.; Awaya, J.; Masuma, R.; Oiwa, R.; Omura, S. J. Antibiot. 1978, 31, 959-965.
4. Hara, M.; Soga, S.; Shono, K.; Eishima, J.; Mizukami, T. J. Antibiot. 2001, 54, 182-186.
5. Salaski, E. J.; Krishnamurthy, G.; Ding, W. D.; Yu, K.; Insaf, S. S.; Eid, C.; Shim, J.; Levin, J. I.; Tabei, K.; Toral-Barza, L.; Zhang, W. G.; McDonald, L. A.; Honores, E.; Hanna, C.; Yamashita, A.; Johnson, B.; Li, Z.; Laakso, L.; Powell, D.; Mansour, T. S. J. Med. Chem. 2009, 52, 2181-2184.
6. Shaaban, K. A.; Wang, X.; Elshahawi, S. I.; Ponomareva, L. V.; Sunkara, M.; Copley, G. C.; Hower, J. C.; Morris, A. J.; Kharel, M. K.; Thorson, J. S. J. Nat. Prod. 2013, 76, 1619-1626.
7. Shaaban, K. A.; Singh, S.; Elshahawi, S. I.; Wang, X.; Ponomareva, L. V.; Sunkara, M.; Copley, G. C.; Hower, J. C.; Morris, A. J.; Kharel, M. K.; Thorson, J. S. J. Antibiot. 2013, DOI: 10.1038/ja.2013.113.
8. Shaaban, K. A.; Singh, S.; Elshahawi, S. I.; Wang, X.; Ponomareva, L. V.; Sunkara, M.; Copley, G. C.; Hower, J. C.; Morris, A. J.; Kharel, M. K.; Thorson, J. S. Nat. Prod. Res. 2013, DOI: 10.1080/14786419.2013.855932.
9. Wang, X.; Shaaban, K. A.; Elshahawi, S. I.; Ponomareva, L. V.; Sunkara, M.; Zhang, Y.; Copley, G. C.; Hower, J. C.; Morris, A. J.; Kharel, M. K.; Thorson, J. S. J. Nat. Prod. 2013, 76, 1441-1447.
10. http://www. youtube.com/watch?v=VglEEjMviVA. University of Kentucky Research Communications, YouTube, Web, 6 Nov. 2013.
11. Zhang, Y.; Wang, X.; Sunkara, M.; Ye, Q.; Ponomareva, L. V.; She, Q.-B.; Morris, A. J.; Thorson, J. S. Org. Lett. 2013, 15, 5566-5569.
12. Laatsch, H. AntiBase 2012; Wiley-VCH: Weinheim, Germany.
13. Menna, M.; Aiello, A.; D'Aniello, F.; Imperatore, C.; Luciano, P.; Vitalone, R.; Irace, C.; Santamaria, R. Eur. J. Org. Chem. 2013, 16, 3241-3246.
14. Piao, S.-J.; Song, Y.-L.; Jiao, W.-H.; Yang, F.; Liu, X.-F.; Chen, W.-S.; Han, B.-N.; Lin, H.-W. Org. Lett. 2013, 15, 3526-3529.
15. O'Boyle, N. M.; Tenderholt, A. L.; Langner, K. M. J. Comput. Chem. 2008, 29, 839-845.
16. Moore, C. B.; Sayers, N.; Mosquera, J.; Slaven, J.; Denning, D. W. J. Infection 2000, 41, 203-220.
17. Kontoyiannis, D. P.; Lewis, R. E.; May, G. S.; Osherov, N.; Rinaldi, M. G. Mycoses 2002, 45, 406-407.
18. Geng, W.-L.; Wang, X.-Y.; Kurtán, T.; Mándi, A.; Tnag, H.; Schulz, B.; Sun, P.; Zhang, W. J. Nat. Prod. 2012, 75, 1828-1832.
19. Fitzgerald, J. T.; Ridley, C. P.; Khosla, C. J. Antibiot. 2011, 64, 759-762.
20. Mikko, M.-K.; Terhi, O.; Takaaki, T.; Susumu, O.; Koji, I. Curr. Opin. Chem. Biol. 2013, 17, 562-570.