Diversity of proton pumps in osteoclasts: V-ATPase with a3 and d2 isoforms is a major form in osteoclasts

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1837, Issue 6, 2014, Pages 744-749

  Matsumoto, Naomi ^a   Daido, Shun ^a   Sun Wada, Ge Hong ^b   Wada, Yoh ^c   Futai, Masamitsu ^a   Nakanishi Matsui, Mayumi ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

a3 knock out mouse; Isoform; Osteoclast; Vacuolar type ATPase

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIUM PHOSPHATE; CATHEPSIN K; OSTEOCLAST DIFFERENTIATION FACTOR; PROTON PUMP; UNCLASSIFIED DRUG; VACUOLAR TYPE ADENOSINE TRIPHOSPHATASE A3 ISOFORM; VACUOLAR TYPE ADENOSINE TRIPHOSPHATASE D2 ISOFORM; ISOENZYME; PRIMER DNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CELL FUSION; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENDOSOME; ESCHERICHIA COLI; LYSOSOME; MACROPHAGE; MOUSE; MULTINUCLEAR CELL; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; SPLEEN; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

MUS;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA PRIMERS; ISOENZYMES; MACROPHAGES; MICE; MICE, KNOCKOUT; OSTEOCLASTS; POLYMERASE CHAIN REACTION; PROTON PUMPS; SPLEEN; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84896690068     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2014.02.011     Document Type: Article

References (23)

1. H. Takayanagi Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems Nat. Rev. Immunol. 7 2007 292 304 (Pubitemid 46480961)
2. J. Xu, T. Cheng, H.T. Feng, N.J. Pavlos, and M.H. Zheng Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis Histol. Histopathol. 22 2007 443 454 (Pubitemid 46647258)
3. S.L. Teitelbaum Bone resorption by osteoclasts Science 289 2000 1504 1508
4. H.C. Blair, S.L. Teitelbaum, R. Ghiselli, and S. Gluck Osteoclastic bone resorption by a polarized vacuolar proton pump Science 245 1989 855 857 (Pubitemid 19223662)
5. +-ATPase type in the ruffled borders of osteoclasts J. Cell Biol. 111 1990 1305 1311
6. +-ATPase with the a3 isoform during osteoclast differentiation J. Biol. Chem. 278 2003 22023 22030 (Pubitemid 36792611)
7. M. Futai, M. Nakanishi-Matsui, H. Okamoto, M. Sekiya, and R.K. Nakamoto Rotational catalysis in proton pumping ATPases: from E. coli F-ATPase to mammalian V-ATPase Biochim. Biophys. Acta 1817 2012 1711 1721
8. M. Forgac Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology Nat. Rev. Mol. Cell Biol. 8 2007 917 929 (Pubitemid 47622561)
9. G.H. Sun-Wada, Y. Wada, and M. Futai Diverse and essential roles of mammalian vacuolar-type proton pump ATPase: toward the physiological understanding of inside acidic compartments Biochim. Biophys. Acta 1658 2004 106 114 (Pubitemid 39013240)
10. +-ATPase in vesicular trafficking: targeting, regulation and function Curr. Opin. Cell Biol. 20 2008 415 426
11. +-ATPase. Preferential expression of the a3 isoform during osteoclast differentiation J. Biol. Chem. 275 2000 8760 8765 (Pubitemid 30180229)
12. Y.P. Li, W. Chen, Y. Liang, E. Li, and P. Stashenko Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification Nat. Genet. 23 1999 447 451
13. J.C. Scimeca, A. Franchi, C. Trojani, H. Parrinello, J. Grosgeorge, C. Robert, O. Jaillon, C. Poirier, P. Gaudray, and G.F. Carle The gene encoding the mouse homologue of the human osteoclast-specific 116-kDa V-ATPase subunit bears a deletion in osteosclerotic (oc/oc) mutants Bone 26 2000 207 213 (Pubitemid 30101642)
14. A. Frattini, P.J. Orchard, C. Sobacchi, S. Giliani, M. Abinun, J.P. Mattsson, D.J. Keeling, A.K. Andersson, P. Wallbrandt, L. Zecca, L.D. Notarangelo, P. Vezzoni, and A. Villa Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis Nat. Genet. 25 2000 343 346 (Pubitemid 30437326)
15. A.N. Smith, K.J. Borthwick, and F.E. Karet Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosis Gene 297 2002 169 177 (Pubitemid 35217792)
16. S.H. Lee, J. Rho, D. Jeong, J.Y. Sul, T. Kim, N. Kim, J.S. Kang, T. Miyamoto, T. Suda, S.K. Lee, R.J. Pignolo, B. Koczon-Jaremko, J. Lorenzo, Y. Choi, v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation, Nat. Med. 12 (2006) 1403-1409. (Pubitemid 44924499)
17. H. Wu, G. Xu, and Y.P. Li Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption J. Bone Miner. Res. 24 2009 871 885
18. M. Nakanishi-Matsui, S. Yano, N. Matsumoto, and M. Futai Lipopolysaccharide induces multinuclear cell from RAW264.7 line with increased phagocytosis activity Biochem. Biophys. Res. Commun. 425 2012 144 149
19. +-ATPase from lysosomes for phagosomal acidification J. Cell Sci. 122 2009 2504 2513
20. S. Furuki, S. Tamura, N. Matsumoto, N. Miyata, A. Moser, H.W. Moser, and Y. Fujiki Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p × Pex6p complex J. Biol. Chem. 281 2006 1317 1323
21. G.H. Sun-Wada, H. Tabata, M. Kuhara, I. Kitahara, Y. Takashima, and Y. Wada Generation of chicken monoclonal antibodies against the a1, a2, and a3 subunit isoforms of vacuolar-type proton ATPase Hybridoma 30 2011 199 203
22. A. Hurtado-Lorenzo, M. Skinner, J. El Annan, M. Futai, G.H. Sun-Wada, S. Bourgoin, J. Casanova, A. Wildeman, S. Bechoua, D.A. Ausiello, D. Brown, and V. Marshansky V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway Nat. Cell Biol. 8 2006 124 136
23. +-ATPase (V-ATPase) and cytohesin-2 J. Biol. Chem. 288 2013 5896 5913