The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus

Journal of General Virology

Volumn 95, Issue PART 4, 2014, Pages 779-786

  Zhang, Hong ^a   Li, Xuyong ^b   Guo, Jing ^b   Li, Li ^a   Chang, Chong ^a   Li, Yuanyuan ^b   Bian, Chao ^c   Xu, Ke ^a   Chen, Hualan ^b   Sun, Bing ^a,c  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; MESSENGER RNA; RNA POLYMERASE; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVIAN INFLUENZA; CELL STRAIN HEK293; CHINA; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; INFLUENZA A; INFLUENZA VIRUS A H7N9; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS ISOLATION; VIRUS MUTATION; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALS; BODY WEIGHT; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFLUENZA A VIRUS, H7N9 SUBTYPE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION, MISSENSE; ORTHOMYXOVIRIDAE INFECTIONS; RNA REPLICASE; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; VIRAL LOAD; VIRAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 84896671181     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.061721-0     Document Type: Article

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