Characterizations of particle size distribution of the droplets exhaled by sneeze

Journal of the Royal Society Interface

Volumn 10, Issue 88, 2013, Pages

  Han, Z Y ^a   Weng, W G ^a   Huang, Q Y ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Airborne infection; Infectious disease; Size distribution; Sneeze

Indexed keywords

DROPS; GEOMETRY; PARTICLE SIZE; PARTICLE SIZE ANALYSIS; PHYSIOLOGICAL MODELS; REGRESSION ANALYSIS; SIZE DISTRIBUTION; STATISTICS;

AIRBORNE INFECTION; DISTRIBUTION CHARACTERISTICS; DISTRIBUTION PARAMETERS; GEOMETRIC STANDARD DEVIATIONS; INFECTIOUS DISEASE; LOG-NORMAL DISTRIBUTION; PHYSIOLOGICAL CHARACTERISTICS; SNEEZE;

DISTRIBUTION FUNCTIONS;

ADOLESCENT; ADULT; ANALYZER; ARTICLE; BREATHING MECHANICS; CALCULATION; COMPUTATIONAL FLUID DYNAMICS; DROPLET SIZE; EVAPORATION; EXHALATION; FEMALE; HUMAN; HUMAN EXPERIMENT; LASER PARTICLE SIZE ANALYZER; LINEAR REGRESSION ANALYSIS; MALE; MEASUREMENT; MOLECULAR STABILITY; NORMAL HUMAN; PARTICLE SIZE; PARTICLE SIZE DISTRIBUTION; PHYSICAL PARAMETERS; RESPIRATORY TRACT INFECTION; SNEEZE DROPLET; SNEEZING; AEROSOL; BIOLOGICAL MODEL; CLINICAL TRIAL;

AEROSOL;

ADOLESCENT; ADULT; AEROSOLS; FEMALE; HUMANS; MALE; MODELS, BIOLOGICAL; PARTICLE SIZE; SNEEZING;

EID: 84896590377     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2013.0560     Document Type: Article

References (57)

1. WHO. 2002 WHO news. Bull. World Health Organization 80, 261.
2. WHO. 2007 International travel and health, p. 74. Geneva, Switzerland: World Health Organization.
3. WHO. 2004 The world health report, pp. 121-123. Geneva, Switzerland: World Health Organization.
4. Morawska L. 2006 Droplet fate in indoor environments, or can we prevent the spread of infection?. Indoor Air 16, 335-347. (doi:10.1111/j.1600-0668.2006. 00432.x)
5. Leder K, Newman D. 2005 Respiratory infections during air travel. Intern. Med. J. 35, 50-55. (doi:10.1111/j.1445-5994.2004.00696.x)
6. Chao CYH, Wan MP, Sze To GN. 2008 Transport and removal of expiratory droplets in hospital ward environment. Aerosol Sci. Technol. 42, 377-394. (doi:10.1080/02786820802104973)
7. Wan MP, To GNS, Chao CYH, Fang L, Melikov A. 2009 Modeling the fate of expiratory aerosols and the associated infection risk in an aircraft cabin environment. Aerosol Sci. Technol. 43, 322-343. (doi:10.1080/02786820802641461)
8. Sze To G.N., Wan MP, Chao CYH, Fang L, Melikov A. 2009 Experimental study of dispersion and deposition of expiratory aerosols in aircraft cabins and impact on infectious disease transmission. Aerosol Sci. Technol. 43, 466-485. (doi:10.1080/02786820902736658)
9. Alford RH, Kasel JA, Gerone P.J., Knight V. 1966 Human influenza resulting from aerosol inhalation. Proc. Soc. Exp. Biol. Med. 122, 800-804. (doi:10.3181/00379727-122-31255)
10. Cole EC, Cook CE 1998 Characterization of infectious aerosols in health care facilities: an aid to effective engineering controls and preventive strategies. Am. J. Infect. Control 26, 453-464. (doi:10.1016/S0196-6553(98) 70046-X)
11. Couch RB, Cate TR, Douglas R.G., Gerone PJ, Knight V. 1966 Effect of route of inoculation on experimental respiratory viral disease in volunteers and evidence for airborne transmission. Bacteriol. Rev. 30, 517-529.
12. Fiegel J, Clarke R, Edwards DA 2006 Airborne infectious disease and the suppression of pulmonary bioaerosols. Drug Discov. Today 11, 51-57. (doi:10.1016/S1359-6446(05)03687-1)
13. Moser MR, Bender TR, Margolis H.S., Noble GR, Kendal AP, Ritter DG 1979 Outbreak of influenza aboard a commercial airliner. Am. J. Epidemiol. 110, 1-6.
14. Xie X, Li Y, Sun H., Liu L. 2009 Exhaled droplets due to talking and coughing. J. R. Soc. Interface 6, S703-S714. (doi:10.1098/rsif.2009.0388.focus)
15. Hersen G, Moularat S, Robine E., Gehin E, Corbet S, Vabret A., Freymuth F. 2008 Impact of health on particle size of exhaled respiratory aerosols: casecontrol study. Clean-Soil Air Water 36, 572-577. (doi:10.1002/clen. 200700189)
16. Holmes NS, Morawska L. 2006 A review of dispersion modelling and its application to the dispersion of particles: an overview of different dispersion models available. Atmos. Environ. 40, 5902-5928. (doi:10.1016/j.atmosenv.2006. 06.003)
17. Li Y, Huang X, Yu ITS, Wong TW, Qian H. 2005 Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong. Indoor Air 15, 83-95. (doi:10.1111/j.1600-0668.2004.00317.x)
18. Qian H, Li Y, Nielsen P.V., Huang X. 2009 Spatial distribution of infection risk of SARS transmission in a hospital ward. Build. Environ. 44, 1651-1658. (doi:10.1016/j.buildenv.2008.11.002)
19. Zhao B, Zhang Z, Li XT 2005 Numerical study of the transport of droplets or particles generated by respiratory system indoors. Build. Environ. 40, 1032-1039. (doi:10.1016/j.buildenv.2004.09.018)
20. Zhu S, Kato S, Yang J-H. 2006 Study on transport characteristics of saliva droplets produced by coughing in a calm indoor environment. Build. Environ. 41, 1691-1702. (doi:10.1016/j.buildenv.2005.06.024)
21. Chao CYH, Wan MP 2006 A study of the dispersion of expiratory aerosols in unidirectional downward and ceiling-return type airflows using a multiphase approach. Indoor Air 16, 296-312. (doi:10.1111/j.1600-0668.2006.00426.x)
22. Wan MP, Chao CYH, Ng YD, To GNS, Yu WC 2007 Dispersion of expiratory droplets in a general hospital ward with ceiling mixing type mechanical ventilation system. Aerosol Sci. Technol. 41, 244-258. (doi:10.1080/ 02786820601146985)
23. Menache MG, Miller FJ, Raabe OG 1995 Particle inhalability curves for humans and small laboratory animals. Ann. Occup. Hyg. 39, 317-328. (doi:10.1093/annhyg/39.3.317)
24. Morrow PE. 1980 Physics of airborne particles and their deposition in the lung. Ann. NY Acad. Sci. 353, 71-80. (doi:10.1111/j.1749-6632.1980.tb18908.x)
25. Duguid JP. 1945 The numbers and sites of origin of the droplets expelled during expiratory activities. Edinb. Med. J. 52, 385-401.
26. Duguid JP. 1946 The size and the duration of aircarriage of respiratory droplets and droplet-nuclei. J. Hyg. 44, 471-479. (doi:10.1017/ S0022172400019288)
27. Gerone PJ, Couch RB, Keefer G.V., Douglas RG, Derrenba EB, Knight V. 1966 Assessment of experimental and natural viral aerosols. Bacteriol. Rev. 30, 576-588.
28. Loudon RG, Roberts RM 1967 Droplet expulsion from respiratory tract. Am. Rev. Respir. Dis. 95, 435-442.
29. Papineni RS, Rosenthal FS 1997 The size distribution of droplets in the exhaled breath of healthy human subjects. J. Aerosol Med. 10, 105-116. (doi:10.1089/jam.1997.10.105)
30. Fennelly KP, Martyny JW, Fulton K.E., Orme IM, Cave DM, Heifets LB 2004 Cough-generated aerosols of Mycobacterium tuberculosis: a new method to study infectiousness. Am. J. Respir. Crit. Care Med. 169, 604-609. (doi:10.1164/rccm.200308-1101OC)
31. Yang S, Lee GWM, Chen C-M, Wu C-C, Yu K-P. 2007 The size and concentration of droplets generated by coughing in human subjects. J. Aerosol Med. 20, 484-494. (doi:10.1089/jam.2007.0610)
32. Johnson GR, Morawska L. 2009 The mechanism of breath aerosol formation. J. Aerosol Med. Pulm. Drug Deliv. 22, 229-237. (doi:10.1089/jamp.2008.0720)
33. Jennison MW. 1942 Atomizing of mouth and nose secretions into the air as revealed by high-speed photography. Aerobiology 17, 106-128.
34. Buckland FE, Tyrrell DAJ. 1964 Experiments on spread of colds: 1. Laboratory studies on dispersal of nasal secretion. J. Hyg. 62, 365-377. (doi:10.1017/S0022172400040080)
35. Chao CYH et al. 2009 Characterization of expiration air jets and droplet size distributions immediately at the mouth opening. J. Aerosol Sci. 40, 122-133. (doi:10.1016/j.jaerosci.2008.10.003)
36. Edwards DA, Man JC, Brand P, Katstra J.P., Sommerer K., Stone HA, Nardell E, Scheuch G. 2004 Inhaling to mitigate exhaled bioaerosols. Proc. Natl Acad. Sci. USA 101, 17383-17388. (doi:10.1073/pnas.0408159101)
37. Fabian P, McDevitt JJ, DeHaan W.H., Fung ROP, Cowling BJ, Chan K.H., Leung GM, Milton DK 2008 Influenza virus in human exhaled breath: an observational study. PLoS ONE 3, e2691. (doi:10.1371/journal.pone.0002691)
38. Wainwright CE et al. 2009 Cough-generated aerosols of Pseudomonas aeruginosa and other Gram-negative bacteria from patients with cystic fibrosis. Thorax 64, 926-931. (doi:10.1136/thx.2008.112466)
39. Almstrand A-C, Bake B., Ljungstrom E, Larsson P, Bredberg A., Mirgorodskaya E, Olin A-C. 2010 Effect of airway opening on production of exhaled particles. J. Appl. Physiol. 108, 584-588. (doi:10.1152/japplphysiol. 00873.2009)
40. Haslbeck K, Schwarz K, Hohlfeld J.M., Seume JR, Koch W. 2010 Submicron droplet formation in the human lung. J. Aerosol Sci. 41, 429-438. (doi:10.1016/j.jaerosci.2010.02.010)
41. Holmgren H, Ljungstrom E, Almstrand A-C, Bake B, Olin A-C. 2010 Size distribution of exhaled particles in the range from 0.01 to 2.0 mm. J. Aerosol Sci. 41, 439-446. (doi:10.1016/j.jaerosci.2010.02.011)
42. Fairchild CI, Stampfer JF 1987 Particle concentration in exhaled breath-summary report. Am. Ind. Hyg. Assoc. J. 48, 948-949. (doi:10.1080/ 15298668791385868)
43. Morawska L, Johnson GR, Ristovski Z.D., Hargreaves M., Mengersen K, Corbett S, Chao CYH, Li Y, Katoshevski D. 2009 Size distribution and sites of origin of droplets expelled from the human respiratory tract during expiratory activities. J. Aerosol Sci. 40, 256-269. (doi:10.1016/j.jaerosci.2008.11.002)
44. Fabian P, Brain J, Houseman E.A., Gern J., Milton DK 2011 Origin of exhaled breath particles from healthy and human rhinovirus-infected subjects. J. Aerosol Med. Pulm. Drug Deliv. 24, 137-147. (doi:10.1089/jamp.2010.0815)
45. Nicas M, Nazaroff WW, Hubbard A. 2005 Toward understanding the risk of secondary airborne infection: emission of respirable pathogens. J. Occup. Environ. Hyg. 2, 143-154. (doi:10.1080/15459620590918466)
46. Johnson GR et al. 2011 Modality of human expired aerosol size distributions. J. Aerosol Sci. 42, 839-851. (doi:10.1016/j.jaerosci.2011.07.009)
47. Xie X, Li Y, Chwang ATY, Ho PL, Seto WH 2007 How far droplets can move in indoor environments: revisiting the Wells evaporation-falling curve. Indoor Air 17, 211-225. (doi:10.1111/j.1600-0668.2007.00469.x)
48. Gao NP, Niu JL 2006 Transient CFD simulation of the respiration process and inter-person exposure assessment. Build. Environ. 41, 1214-1222. (doi:10.1016/j.buildenv.2005.05.014)
49. Gupta JK, Lin CH, Chen Q. 2009 Flow dynamics and characterization of a cough. Indoor Air 19, 517-525. (doi:10.1111/j.1600-0668.2009.00619.x)
50. Gupta JK, Lin C-H, Chen Q. 2010 Characterizing exhaled airflow from breathing and talking. Indoor Air 20, 31-39. (doi:10.1111/j.1600-0668.2009. 00623.x)
51. Gralton J, Tovey E, McLaws M-L, Rawlinson WD 2011 The role of particle size in aerosolised pathogen transmission: a review. J. Infect. 62, 1-13. (doi:10.1016/j.jinf.2010.11.010)
52. Adi H, Larson I, Chiou H., Young P, Traini D, Stewart P. 2006 Agglomerate strength and dispersion of salmeterol xinafoate from powder mixtures for inhalation. Pharm. Res. 23, 2556-2565. (doi:10.1007/s11095-006-9082-6)
53. Dayal P, Shaik MS, Singh M. 2004 Evaluation of different parameters that affect droplet-size distribution from nasal sprays using the Malvern Spraytec. J. Pharm. Sci. 93, 1725-1742. (doi:10.1002/jps.20090)
54. Pilcer G, Sebti T, Amighi K. 2006 Formulation and characterization of lipid-coated tobramycin particles for dry powder inhalation. Pharm. Res. 23, 931-940. (doi:10.1007/s11095-006-9789-4)
55. Simmons MJH, Hanratty TJ 2001 Droplet size measurements in horizontal annular gas-liquid flow. Int. J. Multiphase Flow 27, 861-883. (doi:10.1016/S0301-9322(00)00053-7)
56. Seinfeld JH, Pandis SH 1998 Atmospheric chemistry and physics: from air pollution to climate change. New York, NY: John Wiley & Sons Inc.
57. Lasheras JC, Villermaux E, Hopfinger EJ 1998 Breakup and atomization of a round water jet by a highspeed annular air jet. J. Fluid Mech. 357, 351-379. (doi:10.1017/S0022112097008070)