Effect of airway opening on production of exhaled particles

Journal of Applied Physiology

Volumn 108, Issue 3, 2010, Pages 584-588

  Almstrand, Ann Charlotte ^b   Bake, Björn ^b   Ljungström, Evert ^c   Larsson, Per ^a   Bredberg, Anna ^a   Mirgorodskaya, Ekaterina ^a   Olin, Anna Carin ^a  

^a Occupational and Environmental Medicine   (United States)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Airway closure; Breath

Indexed keywords

BIOLOGICAL MARKER;

ADULT; AGED; ARTICLE; BREATH ANALYSIS; BRONCHIOLE; EQUIPMENT DESIGN; EXHALATION; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; HUMAN; INHALATION; INSTRUMENTATION; LUNG VOLUME; MALE; METABOLISM; MIDDLE AGED; PARTICLE SIZE; RESIDUAL VOLUME; RESPIRATORY SYSTEM; SPIROMETRY; TOTAL LUNG CAPACITY;

ADULT; AGED; BIOLOGICAL MARKERS; BREATH TESTS; BRONCHIOLES; EQUIPMENT DESIGN; EXHALATION; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; HUMANS; INHALATION; LUNG VOLUME MEASUREMENTS; MALE; MIDDLE AGED; PARTICLE SIZE; RESIDUAL VOLUME; RESPIRATORY SYSTEM; SPIROMETRY; TOTAL LUNG CAPACITY;

EID: 77949649568     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00873.2009     Document Type: Article

References (18)

1. Almstrand AC, Ljungstrom E, Lausmaa J, Bake B, Sjovall P, Olin AC. Airway monitoring by collection and mass spectrometric analysis of exhaled particles. Anal Chem 81: 662-668, 2009.
2. Anthonisen NR, Danson J, Robertson PC, Ross WR. Airway closure as a function of age. Respir Physiol 8: 58-65, 1969.
3. Bernhard W, Haagsman HP, Tschernig T, Poets CF, Postle AD, van Eijk ME, von der Hardt H. Conductive airway surfactant: surfacetension function, biochemical composition, and possible alveolar origin. Am J Respir Cell Mol Biol 17: 41-50, 1997.
4. Buist AS, Ross BB. Predicted values for closing volumes using a modified single breadi nitrogen test. Am Rev Respir Dis 107: 744-752, 1973.
5. Dawson SV, Elliott EA. Wave-speed limitation on expiratory flow - a unifying concept. J Appl Physiol 43: 498-515, 1977.
6. Dollfuss RE, Milic-Emili J, Bates DV. Regional ventilation of the lung, studied with boluses of 133xenon. Respir Physiol 2: 234-246, 1967.
7. Edwards DA, Man JC, Brand P, Katstra JP, Sommerer K, Stone HA, Nardell E, Scheuch G. Inhaling to mitigate exhaled bioaerosols. Proc Natl Acad Sci USA 101: 17383-17388, 2004.
8. Halpern D, Grotberg JB. Surfactant effects on fluid-elastic instabilities of liquid-lined flexible tubes: a model of airway closure. J Biomech Eng 115: 271-277, 1993.
9. Hite RD, Seeds MC, Bowton DL, Grier BL, Safta AM, Balkrishnan R, Waite BM, Bass DA. Surfactant phospholipid changes after antigen challenge: a role for phosphatidylglycerol in dysfunction. Am J Physiol, Lung Cell Mol Physiol 288: L610-L617, 2005.
10. Hughes JM, Rosenzweig DY, Kivitz PB. Site of airway closure in excised dog lungs: histologic demonstration. J Appl Physiol 29: 340-344, 1970.
11. Johnson GR, Morawska L. The mechanism of breath aerosol formation. J Aerosol Med Pulm Drug Deliv 22: 229-237, 2009.
12. Mead J, Turner JM, Macklem PT, Little JB. Significance of the relationship between lung recoil and maximum expiratory flow. J Appl Physiol 22: 95-108, 1967.
13. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, Maclntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J. Standardisation of spirometry. Eur Respir J 26: 319-338, 2005.
14. Oxhoj H, Bake B. Measurement of closing volume with the single breath nitrogen method. Scand J Respir Dis 55: 320-331, 1974.
15. Papineni RS, Rosenthal FS. The size distribution of droplets in the exhaled breath of healthy human subjects. J Aerosol Med 10: 105-116, 1997.
16. Poynter SE, LeVine AM. Surfactant biology and clinical application. Crit Care Clin 19: 459-472, 2003.
17. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal Official Statement of the European Respiratory Society. Eur Respir J Suppl 16: 5-40, 1993.
18. Watanabe W, Thomas M, Clarke R, Klibano v AM, Langer R, Katstra J, Fuller GG, Griel LC, Fiegel J, Edwards D. Why inhaling salt water changes what we exhale. J Colloid Interface Sci 307: 71-78, 2007.