Assessment and improvements of Geant4 hadronic models in the context of prompt-gamma hadrontherapy monitoring

Physics in Medicine and Biology

Volumn 59, Issue 7, 2014, Pages 1747-1772

  Dedes, G ^a,b,c   Pinto, M ^a,b   Dauvergne, D ^a,b   Freud, N ^a   Krimmer, J ^a,b   Letang J M ^a   Ray, C ^a,b   Testa, E ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Geant4; hadrontherapy; nuclear models; promot gamma; QMD

Indexed keywords

CARBON; MOLECULAR DYNAMICS; NUCLEAR PHYSICS; OPTIMIZATION; PROTONS; QUALITY ASSURANCE;

GEANT4; HADRON THERAPY; NUCLEAR MODEL; PROMOT-GAMMA; QMD;

MONTE CARLO METHODS;

GAMMA RADIATION; HUMAN; MONTE CARLO METHOD; PROCEDURES; RADIOTHERAPY; THERAPEUTIC USE;

GAMMA RAYS; HUMANS; MONTE CARLO METHOD; RADIOTHERAPY;

EID: 84896537772     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/59/7/1747     Document Type: Article

References (25)

1. Agodi C et al 2012 Precise measurement of prompt photon emission from 80 Mev/u carbon ion beam irradiation J. Instrum. 7 P03001
2. Agostinelli S et al 2003 Geant4 - a simulation toolkit Nucl. Instrum. Methods Phys. Res. A 506 250-303
3. Allison J et al 2006 Geant4 developments and applications IEEE Trans. Nucl. Sci. 53 270-8
4. Braunn B et al 2010 La fragmentation du 12C à 95 MeV par nucléon appliquée au domaine de la hadronthérapie. Etude expérimentale et simulations sur cibles épaisses de PMMA PhD Thesis Université de Caen
5. Braunn B et al 2011 Nuclear reaction measurements of 95 Mev/u 12C interactions on PMMA for hadrontherapy Nucl. Instrum. Methods Phys. Res. B 267 2676-84
6. Folger G et al 2004 The binary cascade nucleon nuclear interactions Eur. J. Phys. A 21 407-17
7. Gasques L R et al 2002 Determination of the C-12 nuclear density through heavy ion elastic scattering experiments Phys. Rev. C 65 044314
8. Gwosch K et al 2013 Non-invasive monitoring of therapeutic carbon ion beams in a homogeneous phantom by tracking of secondary ions Phys. Med. Biol. 58 3755-73
9. Hartnack C et al 1998 Modelling the many-body dynamics of heavy ion collisions: present status and future perspective Eur. J. Phys. A 1 151-69
10. Henriquet P et al 2012 Interaction vertex imaging (IVI) for carbon ion therapy monitoring: a feasibility study Phys. Med. Biol. 57 4655-69
11. Jarlskog C et al 2008 Physics settings for using the Geant4 toolkit in proton therapy IEEE Trans. Nucl. Sci. 55 1018-25
12. Koi T et al 2010 New native QMD code in Geant4 Proc. MC2010 Monte Carlo Conf. (geant4.cern.ch/results/papers/QMD-MC2010.pdf)
13. Lestand L et al 2012 In-beam quality assurance using induced beta plus activity in hadrontherapy: a preliminary physical requirements study using Geant4 Phys. Med. Biol. 57 6497-518
14. Maruyama T et al 1998 Quantum molecular dynamics approach to the nuclear matter below the saturation density Phys. Rev. C 57 655-65
15. Min C H et al 2006 Prompt gamma measurements for locating the dose falloff region in the proton therapy Appl. Phys. Lett. 89 183517
16. Niita K et al 1995 Analysis of the (N, xN′) reaction by quantum molecular dynamics plus statistical decay model Phys. Rev. C 52 2620-35
17. Parodi K et al 2007 Patient study on in vivo verification of beam delivery and range using PET/CT imaging after proton therapy Int. J. Radiat. Oncol. Biol. Phys. 68 920-34
18. Pawelke J et al 1997 In-beam PET imaging for the control of heavy-ion tumour therapy IEEE Trans. Nucl. Sci. 44 1492-8
19. Skyrme T H R 1959 The effective nuclear potential Nucl. Phys. 9 615-34
20. Smeets J et al 2012 Prompt gamma imaging with a slit camera for real-time range control in proton therapy Phys. Med. Biol. 57 3371
21. Testa E et al 2008 Monitoring the Bragg peak location of 73 Mev/u carbon ions by means of prompt gamma-ray measurements Appl. Phys. Lett. 93 093506
22. Testa E et al 2009 Dose profile monitoring with carbon ions by means of prompt-gamma measurements Nucl. Instrum. Methods Phys. Res. B 267 993-6
23. Testa M et al 2010 Real-time monitoring of the Bragg-peak position in ion therapy by means of single photon detection Radiat. Environ. Biophys. 49 337-43
24. Verburg J M et al 2012 Simulation of prompt gamma-ray emission during proton radiotherapy Phys. Med. Biol. 57 5459-72
25. Weisskopf V F et al 1940 On the yield of nuclear reactions with heavy elements Phys. Rev. 57 472