Evaluation of Galleria mellonella larvae for measuring the efficacy and pharmacokinetics of antibiotic therapies against Pseudomonas aeruginosa infection

International Journal of Antimicrobial Agents

Volumn 43, Issue 3, 2014, Pages 254-261

  Hill, Lucy ^a   Veli, Neyme ^a   Coote, Peter J ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Cystic fibrosis; Gram negative infection; Hospital acquired infection; Insect infection model; Resistance

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; CEFOTAXIME; COLISTIN; LEVOFLOXACIN; MEROPENEM; PIPERACILLIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; AREA UNDER THE CURVE; ARTHROPOD LARVA; ARTICLE; BACTERIAL LOAD; BACTERIAL STRAIN; BACTERIAL SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG HALF LIFE; GALLERIA MELLONELLA; IN VITRO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS INFECTION; SINGLE DRUG DOSE;

CYSTIC FIBROSIS; GRAM-NEGATIVE INFECTION; HOSPITAL-ACQUIRED INFECTION; INSECT INFECTION MODEL; RESISTANCE;

ANIMALS; ANTI-BACTERIAL AGENTS; DISEASE MODELS, ANIMAL; HEMOLYMPH; HUMANS; LARVA; LEPIDOPTERA; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84896493427     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2013.11.001     Document Type: Article

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