Detection of Pseudomonas aeruginosa isolates producing VEB-type extended-spectrum β-lactamases in the United Kingdom

Journal of Antimicrobial Chemotherapy

Volumn 62, Issue 6, 2008, Pages 1265-1268

  Woodford, Neil ^a   Zhang, Jiancheng ^a   Kaufmann, Mary E ^a   Yarde, Susannah ^a   Tomas, Maria del Mar ^a   Faris, Camelia ^b   Vardhan, Madhur S ^c   Dawson, Susan ^d   Cotterill, Stephen I ^e   Livermore, David M ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b Wrightington Wigan and Leigh NHS Trust   (United Kingdom)

^c WHISTON HOSPITAL   (United Kingdom)

^d GREAT WESTERN HOSPITAL   (United Kingdom)

^e SALISBURY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

ESBL; Hospital outbreak; International clone; VIM metallo carbapenemase

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE DERIVATIVE; BACTERIAL ENZYME; BETA LACTAM; CEFTAZIDIME; CIPROFLOXACIN; CLAVULANIC ACID; COLISTIN; EDETIC ACID; EXTENDED SPECTRUM BETA LACTAMASE; GENOMIC DNA; GENTAMICIN; IMIPENEM; PROTEIN VEB 1; TOBRAMYCIN; UNCLASSIFIED DRUG;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM DETECTION; BACTERIUM ISOLATE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME SYNTHESIS; HOSPITAL INFECTION; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; PULSED FIELD GEL ELECTROPHORESIS; SEQUENCE ANALYSIS; SEROTYPE; STRAIN DIFFERENCE;

ANTI-BACTERIAL AGENTS; BACTERIAL TYPING TECHNIQUES; BETA-LACTAMASES; BETA-LACTAMS; CLUSTER ANALYSIS; DISEASE OUTBREAKS; DNA FINGERPRINTING; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; GENES, BACTERIAL; GENOTYPE; GREAT BRITAIN; HOSPITALS; HUMANS; INDIA; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SEQUENCE ANALYSIS, DNA; SEROTYPING;

EID: 56649106677     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkn400     Document Type: Article

References (8)

1. Livermore DM, Canton R, Gniadkowski M et al. CTX-M: Changing the face of ESBLs in Europe. J Antimicrob Chemother 2007; 59: 165-74.
2. Canton R, Coque TM. The CTX-M β-lactamase pandemic. Curr Opin Microbiol 2006; 9: 466-75.
3. Naas T, Poirel L, Nordmann P. Minor extended-spectrum β-lactamases. Clin Microbiol Infect 2008; 14: 42-52.
4. Poirel L, Naas T, Guibert M et al. Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum β-lactamase encoded by an Escherichia coli integron gene. Antimicrob Agents Chemother 1999; 43: 573-81.
5. Naas T, Poirel L, Karim A et al. Molecular characterization of In50, a class 1 integron encoding the gene for the extended-spectrum β-lactamase VEB-1 in Pseudomonas aeruginosa. FEMS Microbiol Lett 1999; 176: 411-9.
6. Ellington MJ, Kistler J, Livermore DM et al. Multiplex PCR for rapid detection of genes encoding acquired metallo-β-lactamases. J Antimicrob Chemother 2007; 59: 321-2.
7. VEB gene from a Pseudomonas aeruginosa isolate obtained in India. Antimicrob Agents Chemother 2004; 48 3284-90.
8. Poirel L, Rotimi VO, Mokaddas EM et al. VEB-1-like extended-spectrum β-lactamases in Pseudomonas aeruginosa, Kuwait. Emerg Infect Dis 2001; 7: 468-70.