MyD88- and TRIF-independent induction of Type I interferon drives naive B cell accumulation but not loss of lymph node architecture in lyme disease

Infection and Immunity

Volumn 82, Issue 4, 2014, Pages 1548-1558

  Hastey, Christine J ^a,b,c   Ochoa, Jennine ^a,d   Olsen, Kimberley J ^a   Barthold, Stephen W ^a,b   Baumgarth, Nicole ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of California   (United States)

^d WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR5; CXCL13 CHEMOKINE; INTERFERON; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; SECONDARY LYMPHOID TISSUE CHEMOKINE; SPHINGOSINE KINASE 1; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BONE MARROW; BORRELIA BURGDORFERI; CHIMERA; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE TARGETING; GERMINAL CENTER; HUMORAL IMMUNITY; INNATE IMMUNITY; INTERFERON INDUCTION; LYME DISEASE; LYMPH NODE; LYMPHOCYTE MIGRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANALYSIS OF VARIANCE; ANIMALS; B-LYMPHOCYTES; BORRELIA BURGDORFERI; CHEMOKINES; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; IMMUNITY, CELLULAR; INTERFERON TYPE I; LYME DISEASE; LYMPH NODES; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84896472568     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00969-13     Document Type: Article

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