Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1843, Issue 2, 2014, Pages 234-244

  Duval, D ^a   Lardeux, A ^a   Le Tourneau, T ^a   Norris, R A ^b   Markwald, R R ^b   Sauzeau, V ^a   Probst, V ^a   Le Marec, H ^a   Levine, R ^c   Schott, J J ^a   Merot, J ^a  

^a L INSTITUT DU THORAX   (France)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Filamin A; FilGAP; Mitral valve prolapse; Rac1; RhoA

Indexed keywords

FILAMIN A; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; FILAMIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MUTANT PROTEIN; RAC PROTEIN;

ACTIN FILAMENT; AMINO TERMINAL SEQUENCE; ARTICLE; CELL ADHESION; CELL SPREADING; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; MITRAL VALVE PROLAPSE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; CELL MOTION; CELL SHAPE; CELL SIZE; CHEMISTRY; DEFICIENCY; GENETICS; MESODERM; METABOLISM; MUTATION; PATHOLOGY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; VALVULAR HEART DISEASE;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SHAPE; CELL SIZE; FILAMINS; GTPASE-ACTIVATING PROTEINS; HEART VALVE DISEASES; HUMANS; MESODERM; MUTANT PROTEINS; MUTATION; RAC GTP-BINDING PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; RHOA GTP-BINDING PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84896418022     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.10.022     Document Type: Article

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