-
1
-
-
84865468924
-
The role of PML ubiquitination in human malignancies
-
Chen RH, Lee YR and Yuan WC: The role of PML ubiquitination in human malignancies. J Biomed Sci 19: 81, 2012.
-
(2012)
J Biomed Sci
, vol.19
, pp. 81
-
-
Lee, Y.R.1
Yuan, W.C.2
-
2
-
-
84869163764
-
Targeting neddylation in cancer therapy
-
Duncan K, Schäfer G, Vava A, Parker MI and Zerbini LF: Targeting neddylation in cancer therapy. Future Oncol 8: 1461-1470, 2012.
-
(2012)
Future Oncol
, vol.8
, pp. 1461-1470
-
-
Duncan, K.1
Schäfer, G.2
Vava, A.3
Parker, M.I.4
Zerbini, L.F.5
-
3
-
-
43049154531
-
Alternative UPS drug targets upstream the 26S proteasome
-
Hjerpe R and Rodríguez MS: Alternative UPS drug targets upstream the 26S proteasome. Int J Biochem Cell Biol 40: 1126-1140, 2008.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1126-1140
-
-
Hjerpe, R.1
Rodríguez, M.S.2
-
4
-
-
77449127476
-
Ubiquitin-independent p53 proteasomal degradation
-
Tsvetkov P, Reuven N and Shaul Y: Ubiquitin-independent p53 proteasomal degradation. Cell Death Differ 17: 103-108, 2010.
-
(2010)
Cell Death Differ
, vol.17
, pp. 103-108
-
-
Tsvetkov, P.1
Reuven, N.2
Shaul, Y.3
-
5
-
-
77952548140
-
Targeting the ubiquitin-proteasome system to activate wild-type p53 for cancer therapy
-
Allende-Vega N and Saville MK: Targeting the ubiquitin-proteasome system to activate wild-type p53 for cancer therapy. Semin Cancer Biol 20: 29-39, 2010.
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 29-39
-
-
Allende-Vega, N.1
Saville, M.K.2
-
6
-
-
0032530151
-
Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21 (CIP1/WAF1) and cyclin D proteins
-
Yu ZK, Gervais JL and Zhang H: Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21 (CIP1/WAF1) and cyclin D proteins. Proc Natl Acad Sci USA 95: 11324-11329, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11324-11329
-
-
Yu, Z.K.1
Gervais, J.L.2
Zhang, H.3
-
7
-
-
0034255143
-
Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors
-
Dace A, Zhao L, Park KS, et al: Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors. Proc Natl Acad Sci USA 97: 8985-8990, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8985-8990
-
-
Dace, A.1
Zhao, L.2
Park, K.S.3
-
8
-
-
0034595849
-
A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo
-
Wada H, Yeh ET and Kamitani T: A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo. J Biol Chem 275: 17008-17015, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 17008-17015
-
-
Wada, H.1
Yeh, E.T.2
Kamitani, T.3
-
9
-
-
53249154203
-
Function and regulation of protein neddylation. 'Protein modifications: Beyond the usual suspects' review series
-
Rabut G and Peter M: Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep 9: 969-976, 2008.
-
(2008)
EMBO Rep
, vol.9
, pp. 969-976
-
-
Rabut, G.1
Peter, M.2
-
10
-
-
0034644650
-
Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization
-
Wu K, Chen A and Pan ZQ: Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization. J Biol Chem 275: 32317-32324, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 32317-32324
-
-
Wu, K.1
Chen, A.2
Pan, Z.Q.3
-
11
-
-
63649086487
-
Targeting the ubiquitin system in cancer therapy
-
Hoeller D and Dikic I: Targeting the ubiquitin system in cancer therapy. Nature 458: 438-444, 2009.
-
(2009)
Nature
, vol.458
, pp. 438-444
-
-
Hoeller, D.1
Dikic, I.2
-
12
-
-
63649144413
-
Principles of ubiquitin and SUMO modifications in DNA repair
-
Bergink S and Jentsch S: Principles of ubiquitin and SUMO modifications in DNA repair. Nature 458: 461-467, 2009.
-
(2009)
Nature
, vol.458
, pp. 461-467
-
-
Bergink, S.1
Jentsch, S.2
-
13
-
-
33645538920
-
Mechanistic rationale and clinical evidence for the efficacy of proteasome inhibitors against indolent and mantle cell lymphomas
-
Paoluzzi L and O'Connor OA: Mechanistic rationale and clinical evidence for the efficacy of proteasome inhibitors against indolent and mantle cell lymphomas. BioDrugs 20: 13-23, 2006.
-
(2006)
BioDrugs
, vol.20
, pp. 13-23
-
-
Paoluzzi, L.1
O'Connor, O.A.2
-
14
-
-
33644875054
-
Marked clinical activity of the proteasome inhibitor bortezomib in patients with follicular and mantle-cell lymphoma
-
O'Connor OA: Marked clinical activity of the proteasome inhibitor bortezomib in patients with follicular and mantle-cell lymphoma. Clin Lymphoma Myeloma 6: 191-199, 2005.
-
(2005)
Clin Lymphoma Myeloma
, vol.6
, pp. 191-199
-
-
O'Connor, O.A.1
-
15
-
-
35148886143
-
Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics
-
Yang Y, Kitagaki J, Dai RM, et al: Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics. Cancer Res 67: 9472-9481, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 9472-9481
-
-
Yang, Y.1
Kitagaki, J.2
Dai, R.M.3
-
16
-
-
67449119401
-
Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer
-
Soucy TA, Smith PG and Rolfe M: Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer. Clin Cancer Res 15: 3912-3916, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3912-3916
-
-
Soucy, T.A.1
Smith, P.G.2
Rolfe, M.3
-
17
-
-
35549000516
-
Control of cell proliferation via elevated NEDD8 conjugation in oral squamous cell carcinoma
-
Chairatvit K and Ngamkitidechakul C: Control of cell proliferation via elevated NEDD8 conjugation in oral squamous cell carcinoma. Mol Cell Biochem 306: 163-169, 2007.
-
(2007)
Mol Cell Biochem
, vol.306
, pp. 163-169
-
-
Chairatvit, K.1
Ngamkitidechakul, C.2
-
18
-
-
84864878953
-
Inhibition of the NEDD8 conjugation pathway by shRNA to UBA3, the subunit of the NEDD8-activating enzyme, suppresses the growth of melanoma cells
-
Cheng F, Chen H, Zhang L, Li RH, Liu Y and Sun JF: Inhibition of the NEDD8 conjugation pathway by shRNA to UBA3, the subunit of the NEDD8-activating enzyme, suppresses the growth of melanoma cells. Asian Pac J Cancer Prev 13: 57-62, 2012.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 57-62
-
-
Cheng, F.1
Chen, H.2
Zhang, L.3
Li, R.H.4
Liu, Y.5
Sun, J.F.6
-
19
-
-
64749098830
-
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
-
Soucy TA, Smith PG, Milhollen MA, et al: An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature 458: 732-736, 2009.
-
(2009)
Nature
, vol.458
, pp. 732-736
-
-
Soucy, T.A.1
Smith, P.G.2
Milhollen, M.A.3
-
20
-
-
0034640373
-
Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins
-
Gong L, Kamitani T, Millas S and Yeh ET: Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins. J Biol Chem 275: 14212-14216, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 14212-14216
-
-
Gong, L.1
Kamitani, T.2
Millas, S.3
Yeh, E.T.4
-
21
-
-
10744227299
-
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins
-
Hemelaar J, Borodovsky A, Kessler BM, et al: Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins. Mol Cell Biol 24: 84-95, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 84-95
-
-
Hemelaar, J.1
Borodovsky, A.2
Kessler, B.M.3
-
22
-
-
0031679192
-
Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma
-
Coupland SE, Bechrakis N, Schüler A, Anagnostopoulos I, Hummel M, Bornfeld N and Stein H: Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma. Br J Ophthalmol 82: 961-970, 1998.
-
(1998)
Br J Ophthalmol
, vol.82
, pp. 961-970
-
-
Coupland, S.E.1
Bechrakis, N.2
Schüler, A.3
Anagnostopoulos, I.4
Hummel, M.5
Bornfeld, N.6
Stein, H.7
-
23
-
-
47149085982
-
P21 and p27: Roles in carcinogenesis and drug resistance
-
Abukhdeir AM and Park BH: P21 and p27: roles in carcinogenesis and drug resistance. Expert Rev Mol Med 10: e19, 2008.
-
(2008)
Expert Rev Mol Med
, vol.e19
, pp. 10
-
-
Abukhdeir, A.M.1
Park, B.H.2
-
24
-
-
0036594890
-
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
-
Gartel AL and Tyner AL: The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther 1: 639-649, 2002.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 639-649
-
-
Gartel, A.L.1
Tyner, A.L.2
-
25
-
-
0033593230
-
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
-
Finucane DM, Bossy-Wetzel E, Waterhouse NJ, Cotter TG and Green DR: Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem 274: 2225-2233, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 2225-2233
-
-
Finucane, D.M.1
Bossy-Wetzel, E.2
Waterhouse, N.J.3
Cotter, T.G.4
Green, D.R.5
-
26
-
-
84873648741
-
Ubiquitin family members in the regulation of the tumor suppressor p53
-
Xirodimas DP and Scheffner M: Ubiquitin family members in the regulation of the tumor suppressor p53. Subcell Biochem 54: 116-135, 2010.
-
(2010)
Subcell Biochem
, vol.54
, pp. 116-135
-
-
Xirodimas, D.P.1
Scheffner, M.2
-
27
-
-
84868486281
-
Cellular and computational studies of proteasome inhibition and apoptosis induction in human cancer cells by amino acid Schiff base-copper complexes
-
Zuo J, Bi C, Fan Y, Buac D, Nardon C, Daniel KG and Dou QP: Cellular and computational studies of proteasome inhibition and apoptosis induction in human cancer cells by amino acid Schiff base-copper complexes. J Inorg Biochem 118: 83-93, 2013.
-
(2013)
J Inorg Biochem
, vol.118
, pp. 83-93
-
-
Zuo, J.1
Bi, C.2
Fan, Y.3
Buac, D.4
Nardon, C.5
Daniel, K.G.6
Dou, Q.P.7
|