메뉴 건너뛰기




Volumn 113, Issue 4, 2014, Pages 656-661

Sildenafil citrate improves erectile function after castration in a rat model

Author keywords

castration; orchidectomy; phosphodiesterase type 5 inhibitor; rat; sildenafil

Indexed keywords

SILDENAFIL;

EID: 84896335554     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/bju.12175     Document Type: Article
Times cited : (9)

References (37)
  • 1
    • 84858055379 scopus 로고    scopus 로고
    • Impact of androgen deprivation therapy on sexual function
    • Mazzola CR, Mulhall JP,. Impact of androgen deprivation therapy on sexual function. J Androl 2012; 14: 198-203
    • (2012) J Androl , vol.14 , pp. 198-203
    • Mazzola, C.R.1    Mulhall, J.P.2
  • 2
    • 0028280465 scopus 로고
    • Hormonal therapy for stage D cancer of the prostate
    • Smith AY, Gudziak MR,. Hormonal therapy for stage D cancer of the prostate. West J Med 1994; 160: 351-359
    • (1994) West J Med , vol.160 , pp. 351-359
    • Smith, A.Y.1    Gudziak, M.R.2
  • 3
    • 9544258245 scopus 로고    scopus 로고
    • Mechanisms of venous leakage: A prospective clinicopathological correlation of corporeal function and structure
    • Nehra A, Goldstein I, Pabby A, et al. Mechanisms of venous leakage: a prospective clinicopathological correlation of corporeal function and structure. J Urol 1996; 156: 1320-1329
    • (1996) J Urol , vol.156 , pp. 1320-1329
    • Nehra, A.1    Goldstein, I.2    Pabby, A.3
  • 4
    • 14344264330 scopus 로고    scopus 로고
    • Adipocyte accumulation in penile corpus cavernosum of the orchiectomized rabbit: A potential mechanism for veno-occlusive dysfunction in androgen deficiency
    • Traish AM, Toselli P, Jeong S, Kim NN,. Adipocyte accumulation in penile corpus cavernosum of the orchiectomized rabbit: a potential mechanism for veno-occlusive dysfunction in androgen deficiency. J Androl 2005; 26: 242-248
    • (2005) J Androl , vol.26 , pp. 242-248
    • Traish, A.M.1    Toselli, P.2    Jeong, S.3    Kim, N.N.4
  • 5
    • 79953320193 scopus 로고    scopus 로고
    • Sildenafil promotes smooth muscle preservation and ameliorates fibrosis through modulation of extracellular matrix and tissue growth factor gene expression after bilateral cavernosal nerve resection in the rat
    • Sirad E, Hlaing S, Kovanecz I, et al. Sildenafil promotes smooth muscle preservation and ameliorates fibrosis through modulation of extracellular matrix and tissue growth factor gene expression after bilateral cavernosal nerve resection in the rat. J Sex Med 2011; 8: 1048-1060
    • (2011) J Sex Med , vol.8 , pp. 1048-1060
    • Sirad, E.1    Hlaing, S.2    Kovanecz, I.3
  • 6
    • 0029812277 scopus 로고
    • Androgen and pituitary control of penile nitric oxide synthase and erectile function in the rat
    • Penson DF, Ng C, Cai L, Rajfer J, Gonzalez-Cadavid NF,. Androgen and pituitary control of penile nitric oxide synthase and erectile function in the rat. Biol Reprod 1995; 55: 567-574
    • (1995) Biol Reprod , vol.55 , pp. 567-574
    • Penson, D.F.1    Ng, C.2    Cai, L.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 7
    • 13844271285 scopus 로고    scopus 로고
    • Testosterone regulates PDE5 expression and in vivo responsiveness to tadalafil in rat corpus cavernosum
    • Zhang XH, Morelli A, Luconi M, et al. Testosterone regulates PDE5 expression and in vivo responsiveness to tadalafil in rat corpus cavernosum. Eur Urol 2005; 47: 409-416
    • (2005) Eur Urol , vol.47 , pp. 409-416
    • Zhang, X.H.1    Morelli, A.2    Luconi, M.3
  • 8
    • 34247534567 scopus 로고    scopus 로고
    • Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis in the rat
    • Ferrini MG, Kovanecz I, Sanchez S, et al. Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis in the rat. Biol Reprod 2007; 76: 915-923
    • (2007) Biol Reprod , vol.76 , pp. 915-923
    • Ferrini, M.G.1    Kovanecz, I.2    Sanchez, S.3
  • 9
    • 0347129566 scopus 로고    scopus 로고
    • Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy
    • Schwartz EJ, Wong P, Graydon RJ,. Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy. J Urol 2004; 171: 771-774
    • (2004) J Urol , vol.171 , pp. 771-774
    • Schwartz, E.J.1    Wong, P.2    Graydon, R.J.3
  • 10
    • 0242484067 scopus 로고    scopus 로고
    • A postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneous erectile function after bilateral nerve-sparing radical prostatectomy
    • Padma- Nathan H, McCullough AR, Giuliano F, et al. A postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneous erectile function after bilateral nerve-sparing radical prostatectomy. J Urol 2003; 169 (Suppl. 4): 375
    • (2003) J Urol , vol.169 , Issue.SUPPL. 4 , pp. 375
    • Padma- Nathan, H.1    McCullough, A.R.2    Giuliano, F.3
  • 11
    • 33645729596 scopus 로고    scopus 로고
    • Functional sequelae of cavernous nerve injury in the rat: Is there model dependency
    • Mullerad M, Donohue JF, Li PS, Scardino PT, Mulhall JP,. Functional sequelae of cavernous nerve injury in the rat: is there model dependency. J Sex Med 2006; 3: 77-83
    • (2006) J Sex Med , vol.3 , pp. 77-83
    • Mullerad, M.1    Donohue, J.F.2    Li, P.S.3    Scardino, P.T.4    Mulhall, J.P.5
  • 12
    • 18644367900 scopus 로고    scopus 로고
    • Contemporary patterns of androgen deprivation therapy use for newly diagnosed prostate cancer
    • Meng MV, Grossfeld GD, Sadetsky N, Mehta SS, Lubeck DP, Carroll PR,. Contemporary patterns of androgen deprivation therapy use for newly diagnosed prostate cancer. Urology 2002; 60: 7-11
    • (2002) Urology , vol.60 , pp. 7-11
    • Meng, M.V.1    Grossfeld, G.D.2    Sadetsky, N.3    Mehta, S.S.4    Lubeck, D.P.5    Carroll, P.R.6
  • 13
    • 0037359386 scopus 로고    scopus 로고
    • Effect of androgen deprivation on penile ultrastructure
    • Shen ZJ, Zhou XL, Lu YL, Chen ZD,. Effect of androgen deprivation on penile ultrastructure. Asian J Androl 2003; 5: 33-36
    • (2003) Asian J Androl , vol.5 , pp. 33-36
    • Shen, Z.J.1    Zhou, X.L.2    Lu, Y.L.3    Chen, Z.D.4
  • 15
    • 0347908983 scopus 로고    scopus 로고
    • Effects of medical or surgical castration on erectile function in an animal model
    • Traish AM, Munarriz R, O'Connell L, et al. Effects of medical or surgical castration on erectile function in an animal model. J Androl 2003; 24: 381-387
    • (2003) J Androl , vol.24 , pp. 381-387
    • Traish, A.M.1    Munarriz, R.2    O'Connell, L.3
  • 16
    • 0642312290 scopus 로고    scopus 로고
    • A castrated mouse model of erectile dysfunction
    • Palese MA, Crone JK, Burnett AL,. A castrated mouse model of erectile dysfunction. J Androl 2003; 24: 699-703
    • (2003) J Androl , vol.24 , pp. 699-703
    • Palese, M.A.1    Crone, J.K.2    Burnett, A.L.3
  • 17
    • 9644259802 scopus 로고    scopus 로고
    • Corporal veno-occlusive dysfunction in aging rats: Evaluation by cavernosometry and cavernosography
    • Davila HH, Rajfer J, Gonzalez-Cadavid NF,. Corporal veno-occlusive dysfunction in aging rats: evaluation by cavernosometry and cavernosography. Urology 2004; 64: 1261-1266
    • (2004) Urology , vol.64 , pp. 1261-1266
    • Davila, H.H.1    Rajfer, J.2    Gonzalez-Cadavid, N.F.3
  • 18
    • 0033831101 scopus 로고    scopus 로고
    • Effects of testosterone on the number of NADPH-diaphorase-staining nerve fibers in the rat corpus cavernosum and dorsal nerve
    • Baba K, Yajima M, Carrier S, et al. Effects of testosterone on the number of NADPH-diaphorase-staining nerve fibers in the rat corpus cavernosum and dorsal nerve. Urology 2000; 56: 533-538
    • (2000) Urology , vol.56 , pp. 533-538
    • Baba, K.1    Yajima, M.2    Carrier, S.3
  • 19
    • 0033140355 scopus 로고
    • Effects of castration and testosterone replacement on veno-occlusion during penile erection in the rat
    • Dai YT, Stopper VS, Lewis RW, Mills T,. Effects of castration and testosterone replacement on veno-occlusion during penile erection in the rat. Asian J Androl 1995; 1: 53-59
    • (1995) Asian J Androl , vol.1 , pp. 53-59
    • Dai, Y.T.1    Stopper, V.S.2    Lewis, R.W.3    Mills, T.4
  • 20
    • 0031771616 scopus 로고    scopus 로고
    • Androgenic maintenance of inflow and veno-occlusion during erections in the rat
    • Mills TM, Lewis RW, Stopper VS,. Androgenic maintenance of inflow and veno-occlusion during erections in the rat. Biol Reprod 1998; 59: 1413-1418
    • (1998) Biol Reprod , vol.59 , pp. 1413-1418
    • Mills, T.M.1    Lewis, R.W.2    Stopper, V.S.3
  • 21
    • 0028216450 scopus 로고
    • Effects of castration and androgen replacement on the hemodynamics of penile erection in the rat
    • Mills TM, Stopper VS, Wiedmeier VT,. Effects of castration and androgen replacement on the hemodynamics of penile erection in the rat. Biol Reprod 1994; 51: 234-238
    • (1994) Biol Reprod , vol.51 , pp. 234-238
    • Mills, T.M.1    Stopper, V.S.2    Wiedmeier, V.T.3
  • 22
    • 21644482050 scopus 로고    scopus 로고
    • Erection capability is potentiated by long term sildenafil treatment: Role of blood flow induced endothelial nitric-oxide synthase phosphorylation
    • Musicki B, Champion HC, Becker RE, Liu T, Kramer MF, Burnett AL,. Erection capability is potentiated by long term sildenafil treatment: role of blood flow induced endothelial nitric-oxide synthase phosphorylation. Mol Pharm 2005; 68: 226-232
    • (2005) Mol Pharm , vol.68 , pp. 226-232
    • Musicki, B.1    Champion, H.C.2    Becker, R.E.3    Liu, T.4    Kramer, M.F.5    Burnett, A.L.6
  • 23
    • 0036350615 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits
    • Ockaili R, Salloum F, Hawkins J, Kukreja RC,. Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits. Am J Physiol Heart CircPhysiol 2002; 283: H1263-1269
    • (2002) Am J Physiol Heart CircPhysiol , vol.283
    • Ockaili, R.1    Salloum, F.2    Hawkins, J.3    Kukreja, R.C.4
  • 24
    • 16844382827 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibitor, sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis: Essential role of NO signaling
    • Das A, Xi L, Kukreja RC,. Phosphodiesterase-5 inhibitor, sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis: essential role of NO signaling. J Biol Chem 2005; 280: 12944-12955
    • (2005) J Biol Chem , vol.280 , pp. 12944-12955
    • Das, A.1    Xi, L.2    Kukreja, R.C.3
  • 25
    • 0036783631 scopus 로고    scopus 로고
    • ATP-sensitive K (+) channel activation by nitric oxide and protein kinase G in rabbit ventricular myocytes
    • Han J, Kim N, Joo H, Kim E, Earm YE,. ATP-sensitive K (+) channel activation by nitric oxide and protein kinase G in rabbit ventricular myocytes. Am J Physiol Heart Circ Physiol 2002; 283: H1545-1554
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Han, J.1    Kim, N.2    Joo, H.3    Kim, E.4    Earm, Y.E.5
  • 26
    • 0036011317 scopus 로고    scopus 로고
    • Modulatory activity of sildenafil on copulatorybehaviour of both intact and castrated male rats
    • Ottani A, Giuliani D, Ferrari F,. Modulatory activity of sildenafil on copulatorybehaviour of both intact and castrated male rats. Pharmacol Biochem Behav 2002; 72: 717-722
    • (2002) Pharmacol Biochem Behav , vol.72 , pp. 717-722
    • Ottani, A.1    Giuliani, D.2    Ferrari, F.3
  • 27
    • 0242484067 scopus 로고    scopus 로고
    • Postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneus erectile function after bilateral nerve-sparing radical prostatectomy
    • Padma-Nathan H, Hills B, McCullough AR, et al. Postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneus erectile function after bilateral nerve-sparing radical prostatectomy. J Urol 2003; 169 (Suppl.): 375-376
    • (2003) J Urol , vol.169 , Issue.SUPPL. , pp. 375-376
    • Padma-Nathan, H.1    Hills, B.2    McCullough, A.R.3
  • 28
    • 38149055598 scopus 로고    scopus 로고
    • Effect of sildenafil administration on penile hypoxia induced by cavernous neurotomy in the rat
    • Vignozzi L, Morelli A, Filippi S, et al. Effect of sildenafil administration on penile hypoxia induced by cavernous neurotomy in the rat. Int J Impot Res 2008; 20: 60-67
    • (2008) Int J Impot Res , vol.20 , pp. 60-67
    • Vignozzi, L.1    Morelli, A.2    Filippi, S.3
  • 29
    • 33645976901 scopus 로고    scopus 로고
    • Effect of chronic tadalafil administration on penile hypoxia induced by cavernous neurotomy in the rat
    • Vignozzi L, Morelli A, Filippi S, et al. Effect of chronic tadalafil administration on penile hypoxia induced by cavernous neurotomy in the rat. J Sex Med 2006; 3: 419-431
    • (2006) J Sex Med , vol.3 , pp. 419-431
    • Vignozzi, L.1    Morelli, A.2    Filippi, S.3
  • 30
    • 42949093262 scopus 로고    scopus 로고
    • The functional and structural consequences of cavernous nerve injury are ameliorated by sildenafil citrate
    • Mulhall JP, Muller A, Donohue JF, et al. The functional and structural consequences of cavernous nerve injury are ameliorated by sildenafil citrate. J Sex Med 2008; 5: 1126-1136
    • (2008) J Sex Med , vol.5 , pp. 1126-1136
    • Mulhall, J.P.1    Muller, A.2    Donohue, J.F.3
  • 31
    • 0033941520 scopus 로고    scopus 로고
    • Testosterone supplementation for erectile dysfunction: Results of a meta-analysis
    • Jain P, Rademaker A, McVary K,. Testosterone supplementation for erectile dysfunction: results of a meta-analysis. J Urol 2000; 164: 371-375
    • (2000) J Urol , vol.164 , pp. 371-375
    • Jain, P.1    Rademaker, A.2    McVary, K.3
  • 32
    • 0030814601 scopus 로고    scopus 로고
    • Endocrine screening in 1,022 men with erectile dysfunction: Clinical significance and cost-effective strategy
    • Buvat J, Lemaire A,. Endocrine screening in 1,022 men with erectile dysfunction: clinical significance and cost-effective strategy. J Urol 1997; 158: 1764-1767
    • (1997) J Urol , vol.158 , pp. 1764-1767
    • Buvat, J.1    Lemaire, A.2
  • 33
    • 33644504534 scopus 로고    scopus 로고
    • Sildenafil improves sleep-related erections in hypogonadal men: Evidence from a randomized, placebo-controlled, cross-over study of a synergistic role of both testosterone and sildenafil on penile erections
    • Rochira V, Balestrieri A, Madeo B, Granata AM, Carani C,. Sildenafil improves sleep-related erections in hypogonadal men: evidence from a randomized, placebo-controlled, cross-over study of a synergistic role of both testosterone and sildenafil on penile erections. J Androl 2006; 27: 165-175
    • (2006) J Androl , vol.27 , pp. 165-175
    • Rochira, V.1    Balestrieri, A.2    Madeo, B.3    Granata, A.M.4    Carani, C.5
  • 34
    • 0034851036 scopus 로고    scopus 로고
    • Efficacy and safety of sildenafil citrate for treatment of erectile dysfunction in a population with associated organic risk factors
    • Guay AT, Perez JB, Jacobson J, Newton RA,. Efficacy and safety of sildenafil citrate for treatment of erectile dysfunction in a population with associated organic risk factors. J Androl 2001; 22: 793-797
    • (2001) J Androl , vol.22 , pp. 793-797
    • Guay, A.T.1    Perez, J.B.2    Jacobson, J.3    Newton, R.A.4
  • 35
    • 3142546340 scopus 로고    scopus 로고
    • Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone
    • Shabsigh R, Kaufman JM, Steidle C, Padma-Nathan H,. Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone. J Urol 2004; 172: 658-663
    • (2004) J Urol , vol.172 , pp. 658-663
    • Shabsigh, R.1    Kaufman, J.M.2    Steidle, C.3    Padma-Nathan, H.4
  • 36
    • 78650788563 scopus 로고    scopus 로고
    • Hypogonadal men nonresponders to the PDE5 inhibitor tadalafil benefit from normalization of testosterone levels with a 1% hydroalcoholic testosterone gel in the treatment of erectile dysfunction (TADTEST study)
    • Buvat J, Montorsi F, Maggi M, et al. Hypogonadal men nonresponders to the PDE5 inhibitor tadalafil benefit from normalization of testosterone levels with a 1% hydroalcoholic testosterone gel in the treatment of erectile dysfunction (TADTEST study). J Sex Med 2011; 8: 284-293
    • (2011) J Sex Med , vol.8 , pp. 284-293
    • Buvat, J.1    Montorsi, F.2    Maggi, M.3
  • 37
    • 33745714855 scopus 로고    scopus 로고
    • Combined use of androgen and sildenafil for hypogonadal patients unresponsive to sildenafil alone
    • Hwang T, Chen HE, Tsai TF, Lin YC,. Combined use of androgen and sildenafil for hypogonadal patients unresponsive to sildenafil alone. Int J Impot Res 2006; 18: 400-404
    • (2006) Int J Impot Res , vol.18 , pp. 400-404
    • Hwang, T.1    Chen, H.E.2    Tsai, T.F.3    Lin, Y.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.