Advanced paternal age at birth: Phenotypic and etiologic associations with eating pathology in offspring

Psychological Medicine

Volumn 44, Issue 5, 2014, Pages 1029-1041

  Racine, S E ^a   Culbert, K M ^b   Burt, S A ^a   Klump, K L ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Advanced paternal age; disordered eating; eating disorders; environmental; genetic; twin study

Indexed keywords

ADOLESCENT; CHILD; EATING DISORDERS; FEMALE; GENETICS; HUMAN; PATERNAL AGE; PHENOTYPE; REGISTER; STATISTICS AND NUMERICAL DATA; TWINS; UNITED STATES;

ADOLESCENT; CHILD; DISEASES IN TWINS; EATING DISORDERS; FEMALE; HUMANS; MICHIGAN; PATERNAL AGE; PHENOTYPE; REGISTRIES;

EID: 84896326464     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291713001426     Document Type: Article

References (68)

1. Agrawal A, Balasubramanian S, Smith EK, Madden PA, Bucholz KK, Heath AC, Lynskey MT (2010). Peer substance involvement modifies genetic influences on regular substance involvement in young women. Addiction 105, 1844-1853.
2. APA (2000). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. American Psychiatric Association: Washington, DC.
3. Awadalla P, Gauthier J, Myers RA, Casals F, Hamdan FF, Griffing AR, Côté M, Henrion E, Spiegelman D, Tarabeux J, Piton A, Yang Y, Boyko A, Bustamante C, Xiong L, Rapoport JL, Addington AM, DeLisi JLE, Krebs M, Joober R, Millet B, Fombonne E, Mottron L, Zilversmit M, Keebler J, Daoud H, Marineau C, Roy-Gagnon M, Dube M, Eyre-Walker A, Drapeau P, Stone EA, Lafreniere RG, Rouleau GA (2010). Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. American Journal of Human Genetics 87, 316-324.
4. Burt SA, Klump KL (2013). The Michigan State University Twin Registry: an update. Twin Research and Human Genetics 16, 344-350.
5. Byrne M, Agerbo E, Ewald H, Eaton WW, Mortensen PB (2003). Parental age and risk of schizophrenia: a case-control study. Archives of General Psychiatry 60, 673-678.
6. Cannon M, Jones PB, Murray RM (2002). Obstetric complications and schizophrenia: historical and meta-analytic review. American Journal of Psychiatry 159, 1080-1092.
7. Croen LA, Najjar DV, Fireman B, Grether JK (2007). Maternal and paternal age and risk of autism spectrum disorders. Archives of Pediatrics and Adolescent Medicine 161, 334-340.
8. Croll J, Neumark-Sztainer D, Story M, Ireland M (2002). Prevalence and risk and protective factors related to disordered eating behaviors among adolescents: relationship to gender and ethnicity. Journal of Adolescent Health 31, 166-175.
9. Crow JF (2000). The origins, patterns and implications of human spontaneous mutation. Nature Reviews Genetics 1, 40-47.
10. Culbert KM, Burt SA, McGue M, Iacono WG, Klump KL (2009). Puberty and the genetic diathesis of disordered eating attitudes and behaviors. Journal of Abnormal Psychology 118, 788-796.
11. Doornbos ME, Maas SM, McDonnell J, Vermeiden JPW, Hennekam RCM (2007). Infertility, assisted reproduction technologies and imprinting disturbances: a Dutch study. Human Reproduction 22, 2476-2480.
12. Eriksen W, Sundet JM, Tambs K (2012). Paternal age at birth and the risk of obesity in young adulthood: a register-based birth cohort study of Norwegian males. American Journal of Human Biology 25, 29-34.
13. Fairburn CG, Beglin SJ (1994). Assessment of eating disorders: interview or self-report questionnaire? International Journal of Eating Disorders 16, 363-370.
14. Favaro A, Tenconi E, Santonastaso P (2006). Perinatal factors and the risk of developing anorexia nervosa and bulimia nervosa. Archives of General Psychiatry 63, 82-88.
15. Frans EM, Sandin S, Reichenberg A, Lichtenstein P, Langstrom N, Hultman CM (2008). Advancing paternal age and bipolar disorder. Archives of General Psychiatry 65, 1034-1040.
16. Frieling H, Römer KD, Scholz S, Mittelbach F, Wilhelm J, De Zwaan M, Jacoby GE, Kornhuber J, Hillemacher T, Bleich S (2010). Epigenetic dysregulation of dopaminergic genes in eating disorders. International Journal of Eating Disorders 43, 577-583.
17. Gagne DA, Von Holle A, Brownley KA, Runfola CD, Hofmeier S, Branch KE, Bulik CM (2012). Eating disorder symptoms and weight and shape concerns in a large web-based convenience sample of women ages 50 and above: results of the gender and body image (GABI) study. International Journal of Eating Disorders 45, 832-844.
18. Hare E, Moran P (1979). Raised parental age in psychiatric patients: evidence for the constitutional hypothesis. British Journal of Psychiatry 134, 169-177.
19. Harlap S, Paltiel O, Deutsch L, Knaanie A, Masalha S, Tiram E, Caplan LS, Malaspina D, Friedlander Y (2002). Paternal age and preeclampsia. Epidemiology 13, 660-667.
20. Hultman C, Sandin S, Levine S, Lichtenstein P, Reichenberg A (2011). Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studies. Molecular Psychiatry 16, 1203-1212.
21. Huybrechts I, Himes JH, Ottevaere C, De Vriendt T, De Keyzer W, Cox B, Van Trimpont I, De Bacquer D, De Henauw S (2011). Validity of parent-reported weight and height of preschool children measured at home or estimated without home measurement: a validation study. BMC Pediatrics 11, 63.
22. Insel TR, Cuthbert BN, Garvey MA, Heinssen RK, Pine DS, Quinn KJ, Sanislow CA, Wang PS (2010). Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. American Journal of Psychiatry 167, 748-751.
23. Iossifov I, Ronemus M, Levy D, Wang Z, Hakker I, Rosenbaum J, Yamrom B, Lee Y, Narzisi G, Leotta A, Kendall J, Grabowska E, Ma B, Marks S, Rodgers L, Stepansky A, Troge J, Andrews P, Bekritsky M, Pradhan K, Ghiban E, Kramer M, Parla J, Demeter R, Fulton LL, Fulton RS, Magrini VJ, Ye K, Darnell JC, Darnell RB, Mardis ER, Wilson RK, Schatz MC, McCombie WR, Wigler M (2012). De novo gene disruptions in children on the autistic spectrum. Neuron 74, 285-299.
24. Jacobi C, Hayward C, de Zwaan M, Kraemer HC, Agras WS (2004). Coming to terms with risk factors for eating disorders: application of risk terminology and suggestions for a general taxonomy. Psychological Bulletin 130, 19-65.
25. Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GHT, Wong AHC, Feldcamp LA, Virtanen C, Halfvarson J, Tysk C, McRae AF, Visscher PM, Montgomery GW, Gottesman II, Martin NG, Petronis A (2009). DNA methylation profiles in monozygotic and dizygotic twins. Nature Genetics 41, 240-245.
26. Keel PK, Baxter MG, Heatherton TF, Joiner TE (2007). A 20-year longitudinal study of body weight, dieting, and eating disorder symptoms. Journal of Abnormal Psychology 116, 422-432.
27. Kendler KS, Heath AC, Neale MC, Kessler RC, Eaves LJ (1992). A population-based twin study of alcoholism in women. Journal of the American Medical Association 268, 1877-1882.
28. Killen J, Hayward C, Litt I, Hammer L, Wilson D, Miner B, Taylor C, Varady A, Shisslak C (1992). Is puberty a risk factor for eating disorders? Archives of Pediatrics and Adolescent Medicine 146, 323-325.
29. Klump KL, Bulik CM, Kaye WH, Treasure J, Tyson E (2009). Academy for eating disorders position paper: eating disorders are serious mental illnesses. International Journal of Eating Disorders 42, 97-103.
30. Klump KL, Burt SA (2006). The Michigan State University Twin Registry (MSUTR): genetic, environmental and neurobiological influences on behavior across development. Twin Research and Human Genetics 9, 971-977.
31. Klump KL, Keel PK, Racine SE, Burt SA, Neale M, Sisk C, Boker S, Hu JY (2013). The interactive effects of estrogen and progesterone on changes in emotional eating across the menstrual cycle. Journal of Abnormal Psychology 122, 131-137.
32. Klump KL, Keel PK, Sisk C, Burt SA (2010). Preliminary evidence that estradiol moderates genetic influences on disordered eating attitudes and behaviors during puberty. Psychological Medicine 40, 1745-1753.
33. Klump KL, Perkins PS, Alexandra Burt S, McGue M, Iacono WG (2007). Puberty moderates genetic influences on disordered eating. Psychological Medicine 37, 627-634.
34. Kolko DJ, Kazdin AE (1993). Emotional/behavioral problems in clinic and nonclinic children: correspondence among child, parent and teacher reports. Journal of Child Psychology and Psychiatry 34, 991-1006.
35. Kong A, Frigge ML, Masson G, Besenbacher S, Sulem P, Magnusson G, Gudjonsson SA, Sigurdsson A, Jonasdottir A, Jonasdottir A, Wong WSW, Sigurdsson G, Walters GB, Steinberg S, Helgason H, Thorleifsson G, Gudbjartsson DF, Helgason A, Magnusson OT, Thorsteinsdottir U, Stefansson K (2012). Rate of de novo mutations and the importance of father's age to disease risk. Nature 488, 471-475.
36. Lewinsohn PM, Striegel-Moore RH, Seeley JR (2000). Epidemiology and natural course of eating disorders in young women from adolescence to young adulthood. Journal of the American Academy of Child and Adolescent Psychiatry 39, 1284-1292.
37. Lichtenstein P (2002). The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies. Journal of Internal Medicine 252, 184-205.
38. Lilenfeld LR, Kaye WH, Greeno CG, Merikangas KR, Plotnicov K, Pollice C, Rao R, Strober M, Bulik CM, Nagy L (1998). A controlled family study of anorexia nervosa and bulimia nervosa: psychiatric disorders in first-degree relatives and effects of proband comorbidity. Archives of General Psychiatry 55, 603-610.
39. Liu K, Zerubavel N, Bearman P (2010). Social demographic change and autism. Demography 47, 327-343.
40. Lundström S, Haworth C, Carlström E, Gillberg C, Mill J, Råstam M, Hultman CM, Ronald A, Anckarsäter H, Plomin R, Lichtenstein P, Reichenberg A (2010). Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies. Journal of Child Psychology and Psychiatry 51, 850-856.
41. Lykken D, Bouchard T, McGue M, Tellegen A (1990). The Minnesota Twin Family Registry. Acta Geneticae Medicae et Gemellologiae 39, 35-70.
42. Malaspina D, Corcoran C, Fahim C, Berman A, Harkave-Friedman J, Yale S, Goetz D, Goetz R, Harlap S, Gorman J (2002). Paternal age and sporadic schizophrenia: evidence for de novo mutations. American Journal of Medical Genetics 114, 299-303.
43. Malaspina D, Harlap S, Fennig S, Heiman D, Nahon D, Feldman D, Susser ES (2001). Advancing paternal age and the risk of schizophrenia. Archives of General Psychiatry 58, 361-367.
44. Maloney MJ, McGuire J, Daniels SR, Specker B (1989). Dieting behavior and eating attitudes in children. Pediatrics 84, 482-489.
45. Menezes P, Lewis G, Rasmussen F, Zammit S, Sipos A, Harrison G, Tynelius P, Gunnell D (2010). Paternal and maternal ages at conception and risk of bipolar affective disorder in their offspring. Psychological Medicine 40, 477-485.
46. Merikangas KR, He JP, Brody D, Fisher PW, Bourdon K, Koretz DS (2010). Prevalence and treatment of mental disorders among US children in the 2001-2004 NHANES. Pediatrics 125, 75-81.
47. Miller B, Messias E, Miettunen J, Alaräisänen A, Järvelin MR, Koponen H, Räsänen P, Isohanni M, Kirkpatrick B (2011). Meta-analysis of paternal age and schizophrenia risk in male versus female offspring. Schizophrenia Bulletin 37, 1039-1047.
48. Neale MC (1997). Mx: Statistical Modeling, 4th edn. Department of Psychiatry, Medical College of Virginia: Richmond, VA.
49. Neale MC, Aggen SH, Maes HH, Kubarych TS, Schmitt JE (2006). Methodological issues in the assessment of substance use phenotypes. Addictive Behaviors 31, 1010-1034.
50. O'Dea JA, Caputi P (2001). Association between socioeconomic status, weight, age and gender, and the body image and weight control practices of 6-to 19-year-old children and adolescents. Health Education Research 16, 521-532.
51. Perrin MC, Brown AS, Malaspina D (2007). Aberrant epigenetic regulation could explain the relationship of paternal age to schizophrenia. Schizophrenia Bulletin 33, 1270-1273.
52. Petersen AC, Crockett L, Richards M, Boxer A (1988). A self-report measure of pubertal status: reliability, validity, and initial norms. Journal of Youth and Adolescence 17, 117-133.
53. Purcell S (2002). Variance components models for gene-environment interaction in twin analysis. Twin Research 5, 554-571.
54. Reichenberg A, Gross R, Weiser M, Bresnahan M, Silverman J, Harlap S, Rabinowitz J, Shulman C, Malaspina D, Lubin G, Knobler HY, Davidson M, Susser E (2006). Advancing paternal age and autism. Archives of General Psychiatry 63, 1026-1032.
55. Ronald A, Hoekstra RA (2011). Autism spectrum disorders and autistic traits: a decade of new twin studies. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 156, 255-274.
56. Sartorius GA, Nieschlag E (2010). Paternal age and reproduction. Human Reproduction Update 16, 65-79.
57. Schanen NC (2006). Epigenetics of autism spectrum disorders. Human Molecular Genetics 15, R138-R150.
58. Shah PS (2010). Paternal factors and low birthweight, preterm, and small for gestational age births: a systematic review. American Journal of Obstetrics and Gynecology 202, 103-123.
59. Sobotka T (2010). Shifting parenthood to advanced reproductive ages: trends, causes and consequences. In A Young Generation Under Pressure? (ed. J. C. Tremmel), pp. 129-154. Springer: New York.
60. Steinglass JE, Eisen JL, Attia E, Mayer L, Walsh BT (2007). Is anorexia nervosa a delusional disorder? An assessment of eating beliefs in anorexia nervosa. Journal of Psychiatric Practice 13, 65-71.
61. Swanson SA, Crow SJ, Le Grange D, Swendsen J, Merikangas KR (2011). Prevalence and correlates of eating disorders in adolescents: results from the national comorbidity survey replication adolescent supplement. Archives of General Psychiatry 68, 714-723.
62. Tang CH, Wu MP, Liu JT, Lin HC, Hsu CC (2006). Delayed parenthood and the risk of cesarean delivery-is paternal age an independent risk factor? Birth 33, 18-26.
63. Wade TD, Byrne S, Bryant-Waugh R (2008). The Eating Disorder Examination: norms and construct validity with young and middle adolescent girls. International Journal of Eating Disorders 41, 551-558.
64. Wohl M, Gorwood P (2007). Paternal ages below or above 35 years old are associated with a different risk of schizophrenia in the offspring. European Psychiatry 22, 22-26.
65. Xu B, Roos JL, Dexheimer P, Boone B, Plummer B, Levy S, Gogos JA, Karayiorgou M (2011). Exome sequencing supports a de novo mutational paradigm for schizophrenia. Nature Genetics 43, 864-868.
66. Youngstrom E, Loeber R, Stouthamer-Loeber M (2000). Patterns and correlates of agreement between parent, teacher, and male adolescent ratings of externalizing and internalizing problems. Journal of Consulting and Clinical Psychology 68, 1038-1050.
67. Zhao X, Leotta A, Kustanovich V, Lajonchere C, Geschwind DH, Law K, Law P, Qiu S, Lord C, Sebat J, Ye K, Wigler M (2007). A unified genetic theory for sporadic and inherited autism. Proceedings of the National Academy of Sciences USA 104, 12831-12836.
68. Zucker NL, Losh M, Bulik CM, LaBar KS, Piven J, Pelphrey KA (2007). Anorexia nervosa and autism spectrum disorders: guided investigation of social cognitive endophenotypes. Psychological Bullentin 133, 976-1006.