Endovascular treatment for acute ischemic stroke in octogenarians compared with younger patients: A meta-analysis

International Journal of Stroke

Volumn 9, Issue 3, 2014, Pages 308-312

  Duffis, E Jesús ^a   He, Wenzhuan ^a   Prestigiacomo, Charles J ^a   Gandhi, Chirag D ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Elderly; Endovascular; Ischemic stroke; Thrombolysis

Indexed keywords

AGE; ARTICLE; BLOOD CLOT LYSIS; BRAIN HEMATOMA; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; COMPARATIVE STUDY; HUMAN; META ANALYSIS; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RECANALIZATION; RISK; SYSTEMATIC REVIEW; VERY ELDERLY;

ELDERLY; ENDOVASCULAR; ISCHEMIC STROKE; THROMBOLYSIS;

AGING; BRAIN ISCHEMIA; ENDOVASCULAR PROCEDURES; FEMALE; HUMANS; MALE; STROKE;

EID: 84896317388     PISSN: 17474930     EISSN: 17474949     Source Type: Journal    
DOI: 10.1111/ijs.12098     Document Type: Article

References (20)

1. Feigin VL, Lawes CM, Bennett DA, Anderson CS. Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century. Lancet Neurol 2003; 2:43-53. Epub 2003/07/10.
2. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 1991; 325:445-453. Epub 1991/08/15.
3. Hacke W, Kaste M, Bluhmki E etal. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008; 359:1317-1329. Epub 2008/09/26.
4. Bhatnagar P, Sinha D, Parker RA, Guyler P, O'Brien A. Intravenous thrombolysis in acute ischaemic stroke: a systematic review and meta-analysis to aid decision making in patients over 80 years of age. J Neurol Neurosurg Psychiatry 2011; 82:712-717. Epub 2011/02/05.
5. Sylaja PN, Cote R, Buchan AM, Hill MD. Thrombolysis in patients older than 80 years with acute ischaemic stroke: Canadian Alteplase for Stroke Effectiveness Study. J Neurol Neurosurg Psychiatry 2006; 77:826-829. Epub 2006/03/01.
6. Ghobrial GM, Chalouhi N, Rivers L etal. Multimodal endovascular management of acute ischemic stroke in patients over 75 years old is safe and effective. J Neurointervent Surg 2012; Suppl 1:i33-37. Epub 2012/07/11.
7. Zacharatos H, Hassan AE, Vazquez G etal. Comparison of acute nonthrombolytic and thrombolytic treatments in ischemic stroke patients 80 years or older. Am J Emerg Med 2012; 30:158-164. Epub 2011/01/21.
8. Zeevi N, Kuchel GA, Lee NS, Staff I, McCullough LD. Interventional stroke therapies in the elderly: are we helping? AJNR 2012; 33:638-642. Epub 2011/11/26.
9. Arkadir D, Eichel R, Gomori JM, Ben Hur T, Cohen JE, Leker RR. Multimodal reperfusion therapy for large hemispheric infarcts in octogenarians: is good outcome a realistic goal? AJNR 2012; 33:1167-1169. Epub 2012/02/04.
10. Kim D, Ford GA, Kidwell CS etal. Intra-arterial thrombolysis for acute stroke in patients 80 and older: a comparison of results in patients younger than 80 years. AJNR 2007; 28:159-163. Epub 2007/01/11.
11. Loh Y, Kim D, Shi ZS etal. Higher rates of mortality but not morbidity follow intracranial mechanical thrombectomy in the elderly. AJNR 2010; 31:1181-1185. Epub 2010/04/17.
12. Mazighi M, Labreuche J, Meseguer E etal. Impact of a combined intravenous/intra-arterial approach in octogenarians. Cerebrovasc Dis (Basel, Switzerland) 2011; 31:559-565. Epub 2011/04/14.
13. Mono ML, Romagna L, Jung S etal. Intra-arterial thrombolysis for acute ischemic stroke in octogenarians. Cerebrovasc Dis (Basel, Switzerland) 2012; 33:116-122. Epub 2011/12/20.
14. Pundik S, McWilliams-Dunnigan L, Blackham KL etal. Older age does not increase risk of hemorrhagic complications after intravenous and/or intra-arterial thrombolysis for acute stroke. J Stroke Cerebrovasc Dis 2008; 17:266-272. Epub 2008/08/30.
15. Qureshi AI, Suri MF, Georgiadis AL, Vazquez G, Janjua NA. Intra-arterial recanalization techniques for patients 80 years or older with acute ischemic stroke: pooled analysis from 4 prospective studies. AJNR 2009; 30:1184-1189. Epub 2009/04/04.
16. Kim W-J, Kwon KO, Oh CW etal. Effectiveness and safety of thrombolysis in ischemic stroke patients 80 years or older. Korean J Stroke 2012; 14:19-28.
17. Palumbo V, Boulanger JM, Hill MD, Inzitari D, Buchan AM. Leukoaraiosis and intracerebral hemorrhage after thrombolysis in acute stroke. Neurology 2007; 68:1020-1024. Epub 2007/03/29.
18. Shi ZS, Loh Y, Liebeskind DS etal. Leukoaraiosis predicts parenchymal hematoma after mechanical thrombectomy in acute ischemic stroke. Stroke 2012; 43:1806-1811. Epub 2012/05/15.
19. Sandercock P, Wardlaw JM, Lindley RI etal. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet 2012; 379:2352-2363. Epub 2012/05/29.
20. Mishra NK, Ahmed N, Andersen G etal. Thrombolysis in very elderly people: controlled comparison of SITS International Stroke Thrombolysis Registry and Virtual International Stroke Trials Archive. BMJ (Clin Res Ed) 2010; 341:c6046. Epub 2010/11/26.