Multimodal reperfusion therapy for large hemispheric infarcts in octogenarians: Is good outcome a realistic goal?

American Journal of Neuroradiology

Volumn 33, Issue 6, 2012, Pages 1167-1169

  Arkadir, D ^a   Eichel, R ^a   Gomori, J M ^a   Ben Hur, T ^a   Cohen, J E ^a   Leker, R R ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN RECEPTOR ANTAGONIST;

ADULT; AGED; AGING; ARTICLE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; CEREBROVASCULAR RISK; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; GENERAL CONDITION DETERIORATION; HEART INFARCTION; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; LARGE HEMISPHERIC INFARCT; MAJOR CLINICAL STUDY; MORTALITY; MULTIMODAL REPERFUSION THERAPY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; OCTOGENARIAN; OUTCOME ASSESSMENT; POSTOPERATIVE HEMORRHAGE; PREVALENCE; PROSPECTIVE STUDY; RANKIN SCALE; RECANALIZATION; REPERFUSION; RISK FACTOR; SCORING SYSTEM; TARGET VESSEL RECANALIZATION;

AGED, 80 AND OVER; CEREBRAL INFARCTION; CEREBRAL REVASCULARIZATION; COMBINED MODALITY THERAPY; FEMALE; HUMANS; MALE; OUTCOME ASSESSMENT (HEALTH CARE); TREATMENT OUTCOME;

EID: 84862566569     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A2916     Document Type: Article

References (27)

1. Berrouschot J, Sterker M, Bettin S, et al. Mortality of space-occupying ("malignant") middle cerebral artery infarction under conservative intensive care. Intensive Care Med 1998;24:620-23 (Pubitemid 28344766)
2. Hacke W, Schwab S, Horn M, et al. "Malignant" middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol 1996;53:309-15
3. Christou I, Felberg RA, Demchuk AM, et al. Intravenous tissue plasminogen activator and flow improvement in acute ischemic stroke patients with internal carotid artery occlusion. J Neuroimaging 2002;12:119-23 (Pubitemid 34252426)
4. Derex L, Hermier M, Adeleine P, et al. Influence of the site of arterial occlusion on multiple baseline hemodynamic MRI parameters and post-thrombolytic recanalization in acute stroke. Neuroradiology 2004;46:883-87 (Pubitemid 40057969)
5. Lee KY, Han SW, Kim SH, et al. Early recanalization after intravenous administration of recombinant tissue plasminogen activator as assessed by pre- and post-thrombolytic angiography in acute ischemic stroke patients. Stroke 2007;38:192-93 (Pubitemid 46035627)
6. Linfante I, Llinas RH, Selim M, et al. Clinical and vascular outcome in internal carotid artery versus middle cerebral artery occlusions after intravenous tissue plasminogen activator. Stroke 2002;33:2066-71 (Pubitemid 34840069)
7. Frank JI. Large hemispheric infarction, deterioration, and intracranial pressure. Neurology 1995;45:1286-90
8. Kasner SE, Demchuk AM, Berrouschot J, et al. Predictors of fatal brain edema in massive hemispheric ischemic stroke. Stroke 2001;32:2117-23 (Pubitemid 32868110)
9. Qureshi AI, Suarez JI, Yahia AM, et al. Timing of neurologic deterioration in massive middle cerebral artery infarction: a multicenter review. Crit Care Med 2003;31:272-77 (Pubitemid 36151184)
10. Abou-Chebl A, Bajzer CT, Krieger DW, et al. Multimodal therapy for the treatment of severe ischemic stroke combining GPIIb/IIIa antagonists and angioplasty after failure of thrombolysis. Stroke 2005;36:2286-88 (Pubitemid 41429263)
11. Arnold M, Nedeltchev K, Mattle HP, et al. Intra-arterial thrombolysis in 24 consecutive patients with internal carotid artery T occlusions. J Neurol Neurosurg Psychiatry 2003;74:739-42 (Pubitemid 36628285)
12. Flint AC, Duckwiler GR, Budzik RF, et al. Mechanical thrombectomy of intracranial internal carotid occlusion: pooled results of the MERCI and Multi MERCI Part I trials. Stroke 2007;38:1274-80 (Pubitemid 351664267)
13. Ikushima I, Ohta H, Hirai T, et al. Balloon catheter disruption of middle cerebral artery thrombus in conjunction with thrombolysis for the treatment of acute middle cerebral artery embolism. AJNR Am J Neuroradiol 2007;28:513-17 (Pubitemid 46481896)
14. Imai K, Mori T, Izumoto H, et al. Clot removal therapy by aspiration and extraction for acute embolic carotid occlusion. AJNR Am J Neuroradiol 2006;27:1521-27 (Pubitemid 44260142)
15. Imai K, Mori T, Izumoto H, et al. Emergency carotid artery stent placement in patients with acute ischemic stroke. AJNR Am J Neuroradiol 2005;26:1249-58 (Pubitemid 43821982)
16. Inoue T, Kimura K, Minematsu K, et al. Acase-control analysis of intra-arterial urokinase thrombolysis in acute cardioembolic stroke. Cerebrovasc Dis 2005;19:225-28 (Pubitemid 40591488)
17. Jahan R, Duckwiler GR, Kidwell CS, et al. Intraarterial thrombolysis for treatment of acute stroke: experience in 26 patients with long-term follow-up. AJNR Am J Neuroradiol 1999;20:1291-99 (Pubitemid 29400543)
18. Jovin TG, Gupta R, Uchino K, et al. Emergent stenting of extracranial internal carotid artery occlusion in acute stroke has a high revascularization rate. Stroke 2005;36:2426-30 (Pubitemid 41566971)
19. Levy EI, Ecker RD, Horowitz MB, et al. Stent-assisted intracranial recanalization for acute stroke: early results. Neurosurgery 2006;58:458-63; discussion 458-63
20. Zaidat OO, Suarez JI, Santillan C, et al. Response to intra-arterial and combined intravenous and intra-arterial thrombolytic therapy in patients with distal internal carotid artery occlusion. Stroke 2002;33:1821-26 (Pubitemid 34761068)
21. Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study. Stroke 2004;35:904-11
22. Alexandrov AV, Molina CA, Grotta JC, et al. Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med 2004;351:2170-78 (Pubitemid 39507629)
23. Smith WS, Sung G, Saver J, et al. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 2008;39:1205-12 (Pubitemid 351440692)
24. Khatri P, Hill MD, Palesch YY, et al. Methodology of the Interventional Management of Stroke III Trial. Int J Stroke 2008;3:130-37 (Pubitemid 351566847)
25. Kim D, Ford GA, Kidwell CS, et al. Intra-arterial thrombolysis for acute stroke in patients 80 and older: a comparison of results in patients younger than 80 years. AJNR Am J Neuroradiol 2007;28:159-63 (Pubitemid 46147558)
26. Qureshi AI, Suri MF, Georgiadis AL, et al. Intra-arterial recanalization techniques for patients 80 years or older with acute ischemic stroke: pooled analysis from 4 prospective studies. AJNR Am J Neuroradiol 2009;30:1184-89
27. Hussein HM, Georgiadis AL, Vazquez G, et al. Occurrence and predictors of futile recanalization following endovascular treatment among patients with acute ischemic stroke: a multicenter study. AJNR Am J Neuroradiol 31:454-58