The diagnosis and classification of autoimmune coagulopathy: An updated review

Autoimmunity Reviews

Volumn 13, Issue 4-5, 2014, Pages 587-590

  Chang, Hsiu Hao ^a   Chiang, Bor Luen ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Acquired hemophilia; Acquired inhibitor; Autoantibodies; Autoimmune coagulopathy

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; AUTOANTIBODY; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 13; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 ANTIBODY; BLOOD CLOTTING FACTOR 9; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DESMOPRESSIN; FIBRINOGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; IMMUNOSUPPRESSIVE AGENT; PROTHROMBIN; RITUXIMAB; VITAMIN K GROUP;

AGING; AUTOIMMUNE COAGULOPATHY; AUTOIMMUNE DISEASE; BLEEDING; BLOOD CLOTTING DISORDER; CLINICAL FEATURE; DELAYED DIAGNOSIS; DISEASE CLASSIFICATION; ENVIRONMENTAL FACTOR; HEMOPHILIA A; HUMAN; IMMUNE SYSTEM; IMMUNOADSORPTION; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; MORTALITY; PATHOGENESIS; PLASMAPHERESIS; REVIEW;

ACQUIRED HEMOPHILIA; ACQUIRED INHIBITOR; AUTOANTIBODIES; AUTOIMMUNE COAGULOPATHY;

AUTOANTIBODIES; AUTOIMMUNE DISEASES; BLOOD COAGULATION DISORDERS; BLOOD COAGULATION FACTORS; HUMANS; IMMUNE TOLERANCE; SIGNAL TRANSDUCTION;

EID: 84896317302     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2014.01.032     Document Type: Review

References (39)

1. Ahmed A.E. Autoantibodies to coagulation factors and bleeding disorders. Clin Rev Allergy Immunol 1998, 16:313-319.
2. Franchini M., Lippi G., Favaloro E.J. Acquired inhibitors of coagulation factors: part II. Semin Thromb Hemost 2012, 38:447-453.
3. Dardikh M., Meijer P., van der Meer F., Favaloro E.J., Verbruggen B. Acquired functional coagulation inhibitors: review on epidemiology, results of a wet-workshop on laboratory detection, and implications for quality of inhibitor diagnosis. Semin Thromb Hemost 2012, 38:613-621.
4. Galli M., Luciani D., Bertolini G., Barbui T. Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 2003, 101:1827-1832.
5. Coppola A., Favaloro E.J., Tufano A., Di Minno M.N., Cerbone A.M., Franchini M. Acquired inhibitors of coagulation factors: part I-acquired hemophilia A. Semin Thromb Hemost 2012, 38:433-446.
6. Collins P.W., Hirsch S., Baglin T.P., Dolan G., Hanley J., Makris M., et al. Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation. Blood 2007, 109:1870-1877.
7. Delgado J., Jimenez-Yuste V., Hernandez-Navarro F., Villar A. Acquired haemophilia: review and meta-analysis focused on therapy and prognostic factors. Br J Haematol 2003, 121:21-35.
8. Krishnamurthy P., Hawche C., Evans G., Winter M. A rare case of an acquired inhibitor to factor IX. Haemophilia 2011, 17:712-713.
9. Bortoli R., Monticielo O.A., Chakr R.M., Palominos P.E., Rohsig L.M., Kohem C.L., et al. Acquired factor XI inhibitor in systemic lupus erythematosus-case report and literature review. Semin Arthritis Rheum 2009, 39:61-65.
10. Scott-Timperley L.J., Haire W.D. Autoimmune coagulation disorders. Rheum Dis Clin North Am 1997, 23:411-423.
11. Franchini M., Frattini F., Crestani S., Bonfanti C. Acquired FXIII inhibitors: a systematic review. J Thromb Thrombolysis 2013, 36:109-114.
12. Savage W.J., Kickler T.S., Takemoto C.M. Acquired coagulation factor inhibitors in children after topical bovine thrombin exposure. Pediatr Blood Cancer 2007, 49:1025-1029.
13. Streiff M.B., Ness P.M. Acquired FV inhibitors: a needless iatrogenic complication of bovine thrombin exposure. Transfusion 2002, 42:18-26.
14. Banninger H., Hardegger T., Tobler A., Barth A., Schupbach P., Reinhart W., et al. Fibrin glue in surgery: frequent development of inhibitors of bovine thrombin and human factor V. Br J Haematol 1993, 85:528-532.
15. Ortel T.L., Mercer M.C., Thames E.H., Moore K.D., Lawson J.H. Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin. Ann Surg 2001, 233:88-96.
16. Reding M.T. Immunological aspects of inhibitor development. Haemophilia 2006, 12(Suppl. 6):30-35. [discussion 5-6].
17. Reding M.T., Lei S., Lei H., Green D., Gill J., Conti-Fine B.M. Distribution of Th1- and Th2-induced anti-factor VIII IgG subclasses in congenital and acquired hemophilia patients. Thromb Haemost 2002, 88:568-575.
18. Pavlova A., Diaz-Lacava A., Zeitler H., Satoguina J., Niemann B., Krause M., et al. Increased frequency of the CTLA-4 49 A/G polymorphism in patients with acquired haemophilia A compared to healthy controls. Haemophilia 2008, 14:355-360.
19. Pavlova A., Zeitler H., Scharrer I., Brackmann H.H., Oldenburg J. HLA genotype in patients with acquired haemophilia A. Haemophilia 2010, 16:107-112.
20. Oldenburg J., Zeitler H., Pavlova A. Genetic markers in acquired haemophilia. Haemophilia 2010, 16(Suppl. 3):41-45.
21. Franchini M., Mannucci P.M. Acquired haemophilia A: a 2013 update. Thromb Haemost 2013, 110.
22. Reding M.T., Okita D.K., Diethelm-Okita B.M., Anderson T.A., Conti-Fine B.M. Epitope repertoire of human CD4(+) T cells on the A3 domain of coagulation factor VIII. J Thromb Haemost 2004, 2:1385-1394.
23. Reding M.T., Okita D.K., Diethelm-Okita B.M., Anderson T.A., Conti-Fine B.M. Human CD4+ T-cell epitope repertoire on the C2 domain of coagulation factor VIII. J Thromb Haemost 2003, 1:1777-1784.
24. Green D., Lechner K. A survey of 215 non-hemophilic patients with inhibitors to Factor VIII. Thromb Haemost 1981, 45:200-203.
25. Knoebl P., Marco P., Baudo F., Collins P., Huth-Kuhne A., Nemes L., et al. Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). J Thromb Haemost 2012, 10:622-631.
26. Huth-Kuhne A., Baudo F., Collins P., Ingerslev J., Kessler C.M., Levesque H., et al. International recommendations on the diagnosis and treatment of patients with acquired hemophilia A. Haematologica 2009, 94:566-575.
27. Favaloro E.J., Bonar R., Duncan E., Earl G., Low J., Aboud M., et al. Identification of factor inhibitors by diagnostic haemostasis laboratories: a large multi-centre evaluation. Thromb Haemost 2006, 96:73-78.
28. Favaloro E.J., Bonar R., Duncan E., Earl G., Low J., Aboud M., et al. Mis-identification of factor inhibitors by diagnostic haemostasis laboratories: recognition of pitfalls and elucidation of strategies. A follow up to a large multicentre evaluation. Pathology 2007, 39:504-511.
29. Ewing N.P., Kasper C.K. In vitro detection of mild inhibitors to factor VIII in hemophilia. Am J Clin Pathol 1982, 77:749-752.
30. Lossing T.S., Kasper C.K., Feinstein D.I. Detection of factor VIII inhibitors with the partial thromboplastin time. Blood 1977, 49:793-797.
31. Kershaw G., Favaloro E.J. Laboratory identification of factor inhibitors: an update. Pathology 2012, 44:293-302.
32. Verbruggen B., Novakova I., Wessels H., Boezeman J., van den Berg M., Mauser-Bunschoten E. The Nijmegen modification of the Bethesda assay for factor VIII: C inhibitors: improved specificity and reliability. Thromb Haemost 1995, 73:247-251.
33. Kasper C.K., Aledort L., Aronson D., Counts R., Edson J.R., van Eys J., et al. Proceedings: a more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh 1975, 34:612.
34. Gawryl M.S., Hoyer L.W. Inactivation of factor VIII coagulant activity by two different types of human antibodies. Blood 1982, 60:1103-1109.
35. Franchini M., Lippi G. Acquired factor VIII inhibitors. Blood 2008, 112:250-255.
36. Toschi V., Baudo F. Diagnosis, laboratory aspects and management of acquired hemophilia A. Intern Emerg Med 2010, 5:325-333.
37. Collins P.W. Management of acquired haemophilia A. J Thromb Haemost 2011, 9(Suppl. 1):226-235.
38. Collins P., Baudo F., Huth-Kuhne A., Ingerslev J., Kessler C.M., Castellano M.E., et al. Consensus recommendations for the diagnosis and treatment of acquired hemophilia A. BMC Res Notes 2010, 3:161.
39. Collins P., Baudo F., Knoebl P., Levesque H., Nemes L., Pellegrini F., et al. Immunosuppression for acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). Blood 2012, 120:47-55.