Ratiometric electrochemical proximity assay for sensitive one-step protein detection

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Ren, Kewei ^a   Wu, Jie ^a   Yan, Feng ^b   Ju, Huangxian ^a  

^a NANJING UNIVERSITY   (China)

^b JIANGSU CANCER HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; FERROCENE; FERROUS ION; GOLD; IMMUNOGLOBULIN FC FRAGMENT; METHYLENE BLUE; PROSTATE SPECIFIC ANTIGEN;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; BLOOD; CALIBRATION; CHEMISTRY; DNA PROBE; ELECTROCHEMICAL ANALYSIS; ELECTRODE; GENETIC PROCEDURES; HUMAN; LIMIT OF DETECTION; MALE;

ANTIBODIES; ANTIGEN-ANTIBODY COMPLEX; BIOSENSING TECHNIQUES; CALIBRATION; DNA PROBES; ELECTROCHEMICAL TECHNIQUES; ELECTRODES; FERROUS COMPOUNDS; GOLD; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; LIMIT OF DETECTION; MALE; METHYLENE BLUE; PROSTATE-SPECIFIC ANTIGEN;

EID: 84896297383     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep04360     Document Type: Article

References (52)

1. Zong, C., Wu, J., Wang, C., Ju, H. X. & Yan, F. Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening. Anal. Chem. 84, 2410-2415 (2012).
2. Rusling, J. F. Multiplexed electrochemical protein detection and translation to personalized cancer diagnostics. Anal. Chem. 85, 5304-5310 (2013).
3. Lin, J. H. & Ju, H. X. Electrochemical and chemiluminescent immunosensors for tumor markers. Biosens. Bioelectron. 20, 1461-1470 (2005).
4. Wu, J., Fu, Z. F., Yan, F. & Ju, H. X. Biomedical and clinical applications of immunoassays and immunosensors for tumor markers. TrAC, Trends Anal. Chem. 26, 679-688 (2007). (Pubitemid 47198897)
5. Urdea, M. et al. Requirements for high impact diagnostics in the developingworld. Nature 444, 73-79 (2006).
6. Akter, R., Rahman, M. A. & Rhee, C. K. Amplified electrochemical detection of a cancer biomarker by enhanced precipitation using horseradish peroxidase attached on carbon nanotubes. Anal. Chem. 84, 6407-6415 (2012).
7. Kattah, M. G., Coller, J., Cheung, R. K., Oshidary, N. & Utz, P. J. HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules. Nat. Med. 14, 1284-1289 (2008).
8. Tavoosidana, G. et al. Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer. Proc. Natl. Acad. Sci. U.S.A. 108, 8809-8814 (2011).
9. Cheng, S. Y. et al. Sensitive detection of small molecules by competitive immunomagnetic-proximity ligation assay. Anal. Chem. 84, 2129-2132 (2012).
10. Weibrecht, I. et al. In situ detection of individual mRNA molecules and protein complexes or post-translational modifications using padlock probes combined with the in situ proximity ligation assay. Nat. Protoc. 8, 355-372 (2013).
11. Jung, J., Lifland, A. W., Zurla, C., Alonas, E. J. & Santangelo, P. J. Quantifying RNA-protein interactions in situ usingmodified-MTRIPs and proximity ligation. Nucleic Acids Res. 41, e12 (2013).
12. Nong, R. Y., Gu, J. J., Darmanis, S., KamaliMoghaddam, M. & Landegren, U. DNA-assisted protein detection technologies. Expert Rev. Proteomics 9, 21-32 (2012).
13. Sano, T., Smith, C. L. & Cantor, C. R. Immuno-PCR: very sensitive antigen detection by means of specific antibody-DNA conjugates. Science 258, 120-122 (1992).
14. Burbulis, I., Yamaguchi, K., Gordon, A., Carlson, R. & Brent, R. Using protein-DNA chimeras to detect and count small numbers of molecules. Nat. Methods 2, 31-37 (2005). (Pubitemid 41131055)
15. Guo, Y. C. et al. Phage display mediated immuno-PCR. Nucleic Acids Res. 34, e62 (2006).
16. Wang, T. W., Lu, H. Y., Lou, P. J. & Lin, F. H. Application of highly sensitive, modified glass substrate-based immuno-PCR on the early detection of nasopharyngeal carcinoma. Biomaterials 29, 4447-4454 (2008).
17. Yu, X., Burgoon, M. P., Shearer, A. J. & Gilden, D. H. Characterization of phage peptide interaction with antibody using phage mediated immuno-PCR. J. Immunol. Methods 326, 33-40 (2007). (Pubitemid 47361197)
18. Barletta, J., Bartolome, A. & Constantine, N. T. Immunomagnetic quantitative immuno-PCR for detection of less than one HIV-1 virion. J. Virol. Methods 157, 122-132 (2009).
19. Nam, J. M., Thaxton, C. S. & Mirkin, C. A. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science 301, 1884-1886 (2003). (Pubitemid 37221389)
20. Schweitzer, B. et al. Immunoassays with rolling circle DNA amplification: A versatile platform for ultrasensitive antigen detection. Proc. Natl. Acad. Sci. U.S.A. 97, 10113-10119 (2000).
21. Ericsson, O. et al. A dual-tag microarray platform for high-performance nucleic acid and protein analyses. Nucleic Acids Res. 36, e45 (2008).
22. Schweitzer, B. et al.Multiplexed protein profiling on microarrays by rolling-circle amplification. Nat. Biotechnol. 20, 359-365 (2002). (Pubitemid 34288474)
23. Yan, J. et al. An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids. Small 6, 2520-2525 (2010).
24. Zhang, B. et al. DNA-based hybridization chain reaction for amplified bioelectronic signal and ultrasensitive detection of proteins. Anal. Chem. 84, 5392-5399 (2012).
25. Tong, L.,Wu, J., Li, J., Ju, H. X. & Yan, F. Hybridization chain reaction engineered DNA nanopolylinker for amplified electrochemical sensing of biomarkers. Analyst 138, 4870-4876 (2013).
26. Darmanis, S. et al. Sensitive plasma protein analysis by microparticle-based proximity ligation assays. Mol. Cell. Proteomics 9, 327-335 (2010).
27. Torre, T. Z. G. et al. Sensitive detection of spores using volume-amplified magnetic nanobeads. Small 8, 2174-2177 (2012).
28. Nong, R. Y. et al. Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing. Nat. Protoc. 8, 1234-1248 (2013).
29. Fredriksson, S. et al. Multiplexed protein detection by proximity ligation for cancer biomarker validation. Nat. Methods 4, 327-329 (2007). (Pubitemid 46766977)
30. Tavoosidana, G. et al. Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer. Proc. Natl. Acad. Sci. U.S.A. 108, 8809-8814 (2011).
31. Gullberg, M. et al. Cytokine detection by antibody-based proximity ligation. Proc. Natl. Acad. Sci. U.S.A. 101, 8820-8824 (2004).
32. Weibrecht, I. et al. In situ detection of individual mRNA molecules and protein complexes or post-translational modifications using padlock probes combined with the in situ proximity ligation assay. Nat. Protoc. 8, 355-372 (2013).
33. Jung, J., Lifland, A. W., Zurla, C., Alonas, E. J. & Santangelo, P. J. Quantifying RNA-protein interactions in situ using modified-MTRIPs and proximity ligation. Nucleic Acids Res. 41, e12 (2013).
34. Deng, W. et al.Diagnosis of schistosomiasis japonica with interfacial co-assemblybased multi-channel electrochemical immunosensor arrays. Sci. Rep. 3, 1789 (2013).
35. Fan, C. H., Plaxco, K. W. & Heeger, A. J. Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA. Proc. Natl. Acad. Sci. U.S.A. 100, 9134-9137 (2003). (Pubitemid 37033895)
36. Li, D., Song, S. P. & Fan, C. H. Target-responsive structural switching for nucleic acid-based sensors. Acc. Chem. Res. 43, 631-641 (2010).
37. Kang, D. et al. DNA biomolecular-electronic encoder and decoder devices constructed by multiplex biosensors. NPG Asia Mater. 4, 10.1038/am.2012.1 (2012).
38. Zuo, X. L. et al. A target-responsive electrochemical aptamer switch (TREAS) for reagentless detection of nanomolar ATP. J. Am. Chem. Soc. 129, 1042-1043 (2007).
39. Hu, J. M., Wang, T. Y., Kim, J., Shannon, C. & Easle, C. J. Quantitation of femtomolar protein levels via direct deadout with the electrochemical proximity assay. J. Am. Chem. Soc. 134, 7066-7072 (2012).
40. Zhang, Y. L., Huang, Y., Jiang, J. H., Shen, G. L. & Yu, R. Q. Electrochemical aptasensor based on proximity-dependent surface hybridization assay for singlestep, reusable, sensitive protein detection. J. Am. Chem. Soc. 129, 15448-15449 (2007).
41. Zhang, Y. L., Pang, P. F., Jiang, J. H., Shen, G. L. & Yu, R. Q. Electrochemical aptasensor based on proximity-dependent surface hybridization assay for protein detection. Electroanalysis 21, 1327-1333 (2009).
42. Zhang, P., Beck, T. & Tan,W. H. Design of a molecular beacon DNA probe with two fluorophores. Angew. Chem. Int. Ed. 40, 402-405 (2001). (Pubitemid 32117660)
43. Zhang, H. R., Xu, J. J. & Chen, H. Y. Electrochemiluminescence ratiometry: a new approach to DNA biosensing. Anal. Chem. 85, 5321-5325 (2013).
44. Gong, Y. J. et al. Through bond energy transfer: a convenient and universal strategy toward efficient ratiometric fluorescent probe for bioimaging applications. Anal. Chem. 84, 10777-10784 (2012).
45. Chai, X. L. et al. A two-channel ratiometric electrochemical biosensor for in vivo monitoring of copper ions in a rat brain using gold truncated octahedral microcages. Angew. Chem. Int. Ed. 52, 1-6 (2013).
46. Wu, L., Zhang, X. H., Liu, W., Xiong, E. H. & Chen, J. H. Sensitive electrochemical aptasensor by coupling "signal-on"and "signal-off"strategies. Anal. Chem. 85, 8397-8402 (2013).
47. Cao, Y. et al. Protein detection based on small molecule-linked DNA. Anal. Chem. 84, 4314-4320 (2012).
48. Yang, W. W. & Lai, R. Y. A dual-signalling electrochemical DNA sensor based on target hybridization-induced change in DNA probe flexibility. Chem. Commun. 48, 8703-8705 (2012).
49. Yu, X. et al. Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers. J. Am. Chem. Soc. 128, 11199-11205 (2006). (Pubitemid 44300129)
50. Zani, A., Laschi, S., Mascini, M. & Marrazza, G. A new electrochemical multiplexed assay for PSA cancer marker detection. Electroanalysis 23, 91-99 (2011).
51. Söderberg, O. et al. Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat. Methods 3, 995-1000 (2006). (Pubitemid 44782698)
52. Ferapontova, E. E., Olsen, E. M. & Gothelf, K. V. An RNA aptamer-based electrochemical biosensor for detection of theophylline in serum. J. Am. Chem. Soc. 130, 4256-4258 (2008). (Pubitemid 351466420)