Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 10, 2014, Pages 3751-3756

  Iida, Atsumi ^a   Iwagawa, Toshiro ^a   Kuribayashi, Hiroshi ^a   Satoh, Shinya ^a   Mochizuki, Yujin ^a,b   Baba, Yukihiro ^a   Nakauchi, Hiromitsu ^a   Furukawa, Takahisa ^c   Koseki, Haruhiko ^d   Murakami, Akira ^b   Watanabe, Sumiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

Histone methylation; Interneuron; Progenitor

Indexed keywords

GLUTAMATE AMMONIA LIGASE; HISTONE DEMETHYLASE; HISTONE H3; JMJD3; LYSINE; NEUROGENIC DIFFERENTIATION FACTOR; RECOVERIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BHLHB4; TRANSCRIPTION FACTOR CHX10; TRANSCRIPTION FACTOR VSX1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL FRACTIONATION; CELL MATURATION; CELL POPULATION; CONTROLLED STUDY; DEMETHYLATION; ENZYME ACTIVITY; GENE LOCUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; PHOTORECEPTOR; PLASMID; PRIORITY JOURNAL; PROTEIN FUNCTION; RETINA; RETINA AMACRINE CELL; RETINA BIPOLAR GANGLION CELL; RETINA GANGLION CELL; STEM CELL; UPREGULATION;

HISTONE METHYLATION; INTERNEURON; PROGENITOR;

ANTIBODIES; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BROMODEOXYURIDINE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; ELECTROPORATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HISTONES; HUMANS; IN SITU HYBRIDIZATION; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; METHYLATION; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL BIPOLAR CELLS;

EID: 84896295164     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1311480111     Document Type: Article

References (36)

1. Kooistra SM, Helin K (2012) Molecular mechanisms and potential functions of histone demethylases. Nat Rev Mol Cell Biol 13(5):297-311.
2. Hansen KH, et al. (2008) A model for transmission of the H3K27me3 epigenetic mark.Nat Cell Biol 10(11):1291-1300.
3. Margueron R, et al. (2009) Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 461(7265):762-767.
4. Cao R, Zhang Y (2004) The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr Opin Genet Dev 14(2):155-164.
5. Morey L, Helin K (2010) Polycomb group protein-mediated repression of transcrip tion. Trends Biochem Sci 35(6):323-332.
6. Ringrose L, Paro R (2007) Polycomb/Trithorax response elements and epigenetic memory of cell identity. Development 134(2):223-232.
7. Mohn F, et al. (2008) Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 30(6):755-766.
8. Hirabayashi Y, et al. (2009) Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron 63(5):600-613.
9. Pereira JD, et al. (2010) Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc Natl Acad Sci USA 107(36):15957-15962.
10. Testa G (2011) The time of timing: How Polycomb proteins regulate neurogenesis. Bioessays 33(7):519-528.
11. Agger K, et al. (2007) UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449(7163):731-734.
12. Jepsen K, et al. (2007) SMRT-mediated repression of an H3K27 demethylase in pro gression from neural stem cell to neuron. Nature 450(7168):415-419.
13. Burgold T, etal. (2012) The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep2(5):1244-1258.
14. Marquardt T, Gruss P (2002) Generating neuronal diversity in the retina: One for nearly all. Trends Neurosci 25(1):32-38.
15. Aldiri I, Moore KB, Hutcheson DA, Zhang J, Vetter ML (2013) Polycomb repressive complex PRC2 regulates Xenopus retina development downstream of Wnt/β-catenin signaling. Development 140(14):2867-2878.
16. Kawaguchi A, Ochi H, Sudou N, Ogino H (2012) Comparative expression analysis of the H3K27 demethylases, JMJD3 and UTX, with the H3K27 methylase, EZH2, in Xenopus. Int J Dev Biol 56(4):295-300.
17. Swigut T, Wysocka J (2007) H3K27 demethylases, at long last. Cell 131(1):29-32.
18. Kobayashi M, et al. (1999) Identification of a photoreceptor cell-specific nuclear re ceptor. Proc Natl Acad Sci USA 96(9):4814-4819.
19. Rao RC, et al. (2010) Dynamic patterns of histone lysine methylation in the developing retina. Invest Ophthalmol Vis Sci 51(12):6784-6792.
20. Popova EY, et al. (2012) Stage and gene specific signatures defined by histones H3K4me2 and H3K27me3 accompany mammalian retina maturation in vivo. PLoS ONE 7(10):e46867.
21. Galli-Resta L, Resta G, Tan SS, Reese BE (1997) Mosaics of islet-1-expressing amacrine cells assembled by short-range cellular interactions. J Neurosci 17(20):7831-7838.
22. Elshatory Y, Deng M, Xie X, Gan L (2007) Expression of the LIM-homeodomain protein Isl1 in the developing and mature mouse retina. J Comp Neurol 503(1):182-197.
23. Bramblett DE, Pennesi ME, Wu SM, Tsai MJ (2004) The transcription factor Bhlhb4 is required for rod bipolar cell maturation. Neuron 43(6):779-793.
24. Chow RL, et al. (2004) Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1. Proc Natl Acad Sci USA 1 01 (6):1754-1759.
25. Shi Z, et al. (2011) Vsx1 regulates terminal differentiation of type 7 ON bipolar cells. J Neurosci 31(37):13118-13127.
26. Haverkamp S, Ghosh KK, Hirano AA, Wässle H (2003) Immunocytochemical description of five bipolar cell types of the mouse retina. J Comp Neurol 455(4):463-476.
27. Elshatory Y, et al. (2007) Islet-1 controls the differentiation of retinal bipolar and cholinergic amacrine cells. J Neurosci 27(46):12707-12720.
28. Swaroop A, et al. (1992) A conserved retina-specific gene encodes a basic motif/leucine zipper domain. Proc Natl Acad Sci USA 89(1):266-270.
29. Müller J, et al. (2002) Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 111(2): 197-208.
30. Czermin B, et al. (2002) Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111(2):185-196.
31. Pollak J, et al. (2013) ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors. Development 140(12):2619-2631.
32. Gamm DM, et al. (2008) Regulation of prenatal human retinal neurosphere growth and cell fate potential by retinal pigment epithelium and Mash1. Stem Cells 26(12):3182-3193.
33. Akizu N, Estarás C, Guerrero L, Martí E, Martínez-Balbás MA (2010) H3K27me3 reg ulates BMP activity in developing spinal cord. Development 137(17):2915-2925.
34. Burgold T, et al. (2008) The histone H3 lysine 27-specific demethylase Jmjd3 is re quired for neural commitment. PLoS ONE 3(8):e3034.
35. De Santa F, et al. (2007) The histone H3 lysine-27 demethylase Jmjd3 links inflam mation to inhibition of polycomb-mediated gene silencing. Cell 130(6):1083-1094.
36. Satoh T, et al. (2010) The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol 11 (10):936-944.