Absorptive chemistry based extraction for LC-MS/MS analysis of small molecule analytes from biological fluids-an application for 25-hydroxyvitamin D

Clinical Chemistry and Laboratory Medicine

Volumn 52, Issue 3, 2014, Pages 363-371

  Baecher, Silvia ^a   Geyer, Roland ^b   Lehmann, Christine ^b   Vogeser, Michael ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b Tecan Schweiz AG   (Switzerland)

Author keywords

25 hydroxyvitamin D (25OHD); Clinical mass spectrometry; Immobilized liquid extraction (ILE); Liquid chromatography tandem mass spectrometry (LC MS MS); Tecan AC Extraction Plate ; Tecan Immobilized Coating Extraction (TICE )

Indexed keywords

25 HYDROXYVITAMIN D;

ANALYTIC METHOD; ARTICLE; BODY FLUID; CHEMICAL ANALYSIS; EXTRACTION; ISOTOPE DILUTION ASSAY; LABORATORY AUTOMATION; LABORATORY DEVICE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MEASUREMENT ACCURACY; PRECIPITATION; PRIORITY JOURNAL; PROTEIN PRECIPITATION; QUANTITATIVE ASSAY; REPRODUCIBILITY; ROBOTICS; TANDEM MASS SPECTROMETRY; TECAN IMMOBILIZED COATING EXTRACTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ABSORPTION; BLOOD CHEMICAL ANALYSIS; CALIBRATION; CHROMATOGRAPHY, LIQUID; HUMANS; LIMIT OF DETECTION; LINEAR MODELS; QUALITY CONTROL; TANDEM MASS SPECTROMETRY; VITAMIN D;

EID: 84896122360     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2013-0534     Document Type: Article

References (6)

1. Vogeser M, Kirchhoff F. Progress in automation of LC-MS in laboratory medicine. Clin Biochem 2011;44:4-13.
2. Carter GD, Berry JL, Gunter E, Jones G, Jones JC, Makin HL, et al. Proficiency testing of 25-hydroxyvitamin D (25-OHD) assays. J Steroid Biochem Mol Biol 2010;121:176-9.
3. Tai SS, Bedner M, Phinney KW. Development of a candidate reference measurement procedure for the determination of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry. Anal Chem 2010;82:1942-8.
4. Matuszewski BK, Constanzer ML, Chavez-Eng CM. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal Chem 2003;75:3019-30.
5. Bonfiglio R, King RC, Olah TV, Merkle K. The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds. Rapid Commun Mass Spectrom 1999;13:1175-85.
6. van den Ouweland JM, Vogeser M, Bacher S. Vitamin D and metabolites measurement by tandem mass spectrometry. Rev Endocr Metab Disord 2013;14:159-84.