Morphologic changes of dendritic spines of striatal neurons in the levodopa-induced dyskinesia model

Movement Disorders

Volumn 29, Issue 3, 2014, Pages 336-343

  Nishijima, Haruo ^a,b   Suzuki, Satoko ^a   Kon, Tomoya ^a   Funamizu, Yukihisa ^a   Ueno, Tatsuya ^a,b   Haga, Rie ^a   Suzuki, Chihiro ^a   Arai, Akira ^a   Kimura, Tamaki ^a   Suzuki, Chieko ^a   Meguro, Reiko ^b   Miki, Yasuo ^b   Yamada, Junko ^b   Migita, Keisuke ^b   Ichinohe, Noritaka ^b   Ueno, Shinya ^b   Baba, Masayuki ^a   Tomiyama, Masahiko ^a,b  

^a AOMORI PREFECTURAL CENTRAL HOSPITAL   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

Dendritic spine; Dyskinesia; Morphologic change; Parkinson's disease; Synaptic plasticity

Indexed keywords

LEVODOPA; OXIDOPAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DENSITY; CELL STRUCTURE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CORPUS STRIATUM; DENDRITIC SPINE; DYSKINESIA; GLOBUS PALLIDUS; LEVODOPA INDUCED DYSKINESIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; DISEASE MODEL; DRUG EFFECTS; METABOLISM; NEOSTRIATUM; NERVE CELL; NEURITE; PARKINSON DISEASE; PATHOLOGY; SYNAPSE; WISTAR RAT;

ANIMALS; CORPUS STRIATUM; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; DYSKINESIA, DRUG-INDUCED; LEVODOPA; MALE; NEOSTRIATUM; NEURITES; NEURONS; PARKINSON DISEASE; RATS, WISTAR; SYNAPSES;

EID: 84896120706     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25826     Document Type: Article

References (36)

1. Cenci MA. Dopamine dysregulation of movement control in L-DOPA-induced dyskinesia. Trends Neurosci 2007;30:236-243.
2. Olanow CW, Obeso JA. Preventing levodopa-induced dyskinesias. Ann Neurol 2000;47(4 suppl 1):S167-S176; discussion S176-S168.
3. Olanow CW, Obeso JA, Stocchi F. Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications. Lancet Neurol 2006;5:677-687.
4. Pavese N, Evans AH, Tai YF, Hotton G, Brooks DJ, Lees AJ, Piccini P. Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study. Neurology 2006;67:1612-1617.
5. Calabresi P, Di Filippo M, Ghiglieri V, Tambasco N, Picconi B. Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap. Lancet Neurol 2010;9:1106-1117.
6. Picconi B, Centonze D, Hakansson K, et al. Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia. Nat Neurosci 2003;6:501-506.
7. Picconi B, Paille V, Ghiglieri V, et al. L-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation. Neurobiol Dis 2008;29:327-335.
8. Matsuzaki M, Honkura N, Ellis-Davies GC, Kasai H. Structural basis of long-term potentiation in single dendritic spines. Nature 2004;429:761-766.
9. Kasai H, Fukuda M, Watanabe S, Hayashi-Takagi A, Noguchi J. Structural dynamics of dendritic spines in memory and cognition. Trends Neurosci 2010;33:121-129.
10. Nishijima H, Arai A, Kimura T, et al. Drebrin immunoreactivity in the striatum of a rat model of levodopa-induced dyskinesia. Neuropathology 2013;33:391-396.
11. Zhang Y, Meredith GE, Mendoza-Elias N, Rademacher DJ, Tseng KY, Steece-Collier K. Aberrant restoration of spines and their synapses in L-DOPA-induced dyskinesia: involvement of corticostriatal but not thalamostriatal synapses. J Neurosci 2013;33:11655-11667.
12. DeLong MR, Wichmann T. Circuits and circuit disorders of the basal ganglia. Arch Neurol 2007;64:20-24.
13. Gerfen CR. D1 dopamine receptor supersensitivity in the dopamine-depleted striatum animal model of Parkinson's disease. Neuroscientist 2003;9:455-462.
14. Santini E, Valjent E, Fisone G. Parkinson's disease: levodopa-induced dyskinesia and signal transduction. FEBS J 2008;275:1392-1399.
15. Bateup HS, Santini E, Shen W, et al. Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors. Proc Natl Acad Sci U S A 2010;107:14845-14850.
16. Iravani MM, McCreary AC, Jenner P. Striatal plasticity in Parkinson's disease and L-dopa induced dyskinesia. Parkinsonism Relat Disord 2012;18(suppl 1):S123-S125.
17. Tanaka H, Kannari K, Maeda T, Tomiyama M, Suda T, Matsunaga M. Role of serotonergic neurons in L-DOPA-derived extracellular dopamine in the striatum of 6-OHDA-lesioned rats. Neuroreport 1999;10:631-634.
18. Maeda T, Kannari K, Suda T, Matsunaga M. Loss of regulation by presynaptic dopamine D2 receptors of exogenous L-DOPA-derived dopamine release in the dopaminergic denervated striatum. Brain Res 1999;817(1-2):185-191.
19. Lindgren HS, Andersson DR, Lagerkvist S, Nissbrandt H, Cenci MA. L-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: temporal and quantitative relationship to the expression of dyskinesia. J Neurochem 2010;112:1465-1476.
20. Cenci MA, Lundblad M. Ratings of L-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and mice. Curr Protoc Neurosci 2007;Chaptwe 9:Unit 9.25.
21. Deng YP, Lei WL, Reiner A. Differential perikaryal localization in rats of D1 and D2 dopamine receptors on striatal projection neuron types identified by retrograde labeling. J Chem Neuroanat 2006;32(2-4):101-116.
22. Tomiyama M, Mori F, Kimura T, Ichinohe N, Wakabayashi K, Matsunaga M, Baba M. Hypertrophy of medial globus pallidus and substantia nigra reticulata in 6-hydroxydopamine-lesioned rats treated with L-DOPA: implication for L-DOPA-induced dyskinesia in Parkinson's disease. Neuropathology 2004;24:290-295.
23. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. 6th ed. Boston, MA: Academic Press/Elsevier; 2007.
24. Wilson CJ. Understanding the neostriatal microcircuitry: high-voltage electron microscopy. Microsc Res Tech 1994;29:368-380.
25. Neely MD, Schmidt DE, Deutch AY. Cortical regulation of dopamine depletion-induced dendritic spine loss in striatal medium spiny neurons. Neuroscience 2007;149:457-464.
26. Stephens B, Mueller AJ, Shering AF, et al. Evidence of a breakdown of corticostriatal connections in Parkinson's disease. Neuroscience 2005;132:741-754.
27. Zaja-Milatovic S, Milatovic D, Schantz AM, et al. Dendritic degeneration in neostriatal medium spiny neurons in Parkinson disease. Neurology 2005;64:545-547.
28. Day M, Wang Z, Ding J, et al. Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nat Neurosci 2006;9:251-259.
29. Villalba RM, Lee H, Smith Y. Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys. Exp Neurol 2009;215:220-227.
30. Soderstrom KE, O'Malley JA, Levine ND, Sortwell CE, Collier TJ, Steece-Collier K. Impact of dendritic spine preservation in medium spiny neurons on dopamine graft efficacy and the expression of dyskinesias in parkinsonian rats. Eur J Neurosci 2010;31:478-490.
31. Holtmaat A, Svoboda K. Experience-dependent structural synaptic plasticity in the mammalian brain. Nat Rev Neurosci 2009;10:647-658.
32. Silverdale MA, Kobylecki C, Hallett PJ, et al. Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate. Synapse 2010;64:177-180.
33. Cenci MA, Konradi C. Maladaptive striatal plasticity in L-DOPA-induced dyskinesia. Prog Brain Res 2010;183:209-233.
34. Togasaki DM, Tan L, Protell P, Di Monte DA, Quik M, Langston JW. Levodopa induces dyskinesias in normal squirrel monkeys. Ann Neurol 2001;50:254-257.
35. Fujiyama F, Sohn J, Nakano T, Furuta T, Nakamura KC, Matsuda W, Kaneko T. Exclusive and common targets of neostriatofugal projections of rat striosome neurons: a single neuron-tracing study using a viral vector. Eur J Neurosci 2011;33:668-677.
36. Kawaguchi Y, Wilson CJ, Emson PC. Intracellular recording of identified neostriatal patch and matrix spiny cells in a slice preparation preserving cortical inputs. J Neurophysiol 1989;62:1052-1068.