Differential perikaryal localization in rats of D1 and D2 dopamine receptors on striatal projection neuron types identified by retrograde labeling

Journal of Chemical Neuroanatomy

Volumn 32, Issue 2-4, 2006, Pages 101-116

  Deng, Yun Ping ^a   Lei, Wan Long ^a,b   Reiner, Anton ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Basal ganglia; Dopamine receptor; Immunohistochemistry; Localization; Striatum

Indexed keywords

DEXTRAN DERIVATIVE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; RHODAMINE;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LABELING; ANTIBODY SPECIFICITY; ARTICLE; CELL LABELING; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CORPUS STRIATUM; GLOBUS PALLIDUS; MALE; NERVE CELL; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SUBSTANTIA NIGRA;

ANIMALS; CORPUS STRIATUM; DOPAMINE; EFFERENT PATHWAYS; GLOBUS PALLIDUS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SUBSTANTIA NIGRA; SYNAPTIC TRANSMISSION;

EID: 33751183321     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchemneu.2006.07.001     Document Type: Article

References (82)

1. Aizman O., Brismar H., Uhlen P., Zettergren E., Levey A.I., Forssberg H., Greengard P., and Aperia A. Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons. Nat. Neurosci. 3 (2000) 226-230
2. Albin R.L., Young A.B., and Penney J.B. The functional anatomy of basal ganglia disorders. Trends Neurosci. 12 (1989) 366-375
3. Ariano M.A., and Sibley D.R. Dopamine receptor distribution in the rat CNS: elucidation using anti-peptide antisera directed against D1A and D3 subtypes. Brain Res. 649 (1994) 95-110
4. Ariano M.A., Stromski C.J., Smyk-Randall E.M., and Sibley D.R. D2 dopamine receptor localization on striato-nigral neurons. Neurosci. Lett. 144 (1992) 215-220
5. Aubert I., Ghorayeb I., Normand E., and Bloch B. Phenotypical characterization of the neurons expressing the D1 and D2 dopamine receptors in the monkey striatum. J. Comp. Neurol. 418 (2000) 22-32
6. Beckstead R.M. Association of dopamine D1 and D2 receptors with specific cellular elements in the basal ganglia of the cat: the uneven topography of dopamine receptors in the striatum is determined by intrinsic striatal cells, not nigrostriatal axons. Neuroscience 27 (1988) 851-863
7. Blank T., Nijholt I., Teichert U., Kugler H., Behrsing H., Fienberg A., Greengard P., and Spiess J. The phosphoprotein DARPP32 mediates cAMP-dependent potentiation of striatal N-methyl-d-aspartate responses. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 14859-14864
8. Bolam J.P., and Bennett B.D. Microcircuitry of the neostriatum. In: Ariano M.A., and Surmeier D.J. (Eds). Molecular and Cellular Mechanisms of Neostriatal Function (1995), Springer-Verlag, Berlin 1-19
9. Bouthenet M.L., Souil E., Martres M.P., Sokoloff P., Giros B., and Schwartz J.C. Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine receptor mRNA. Brain Res. 564 (1991) 203-219
10. Chen J.F., Qin Z.H., Szele F., Bai G., and Weiss B. Neuronal localization and modulation of the D2 dopamine receptor mRNA in brain of normal mice and mice lesioned with 6-hydroxydopamine. Neuropharmacology 30 (1991) 927-941
11. Chen Q., Veenman C.L., and Reiner A. Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity. Neuroscience 73 (1996) 715-731
12. Chen Q., Surmeier D.J., and Reiner A. NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. Exp. Neurol. 159 (1999) 283-296
13. Civelli O., Bunzow J.R., Grandy D.K., Zhou Q.Y., and Van Tol H.H.M. Molecular biology of the dopamine receptors. Eur. J. Pharmacol. 207 (1991) 277-286
14. Clark D., and White F.J. D1 dopamine receptor-the search for a function: a critical evaluation of the D1/D2 dopamine receptor classification and its functional implications. Synapse 1 (1987) 347-388
15. Dearry A., Gingrich J.A., Falardeau P., Fremeau Jr. R.T., Bates M.D., and Caron M.G. Molecular cloning and expression of the gene for a human D1 dopamine receptor. Nature 347 (1990) 72-76
16. DeKeyser J. Subtypes and localization of dopamine receptors in human brain. Neurochem. Int. 22 (1993) 83-93
17. DeLong M. Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 13 (1990) 281-285
18. Deng Y.P., Albin R.L., Penney J.B., Young A.B., Anderson K.D., and Reiner A. Differential loss of striatal projection neurons in Huntington's disease: a quantitative immunohistochemical study. J. Chem. Neuroanat. 27 (2004) 143-164
19. Diaz J., Levesque D., Lammers C.H., Griffon N., Martres M.P., Schwartz J.C., and Sokoloff P. Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain. Neuroscience 65 (1995) 731-745
20. Dragunow M., Robertson G.S., Faull R.L.M., Robertson H.A., and Jansen K. D1 dopamine receptor antagonists induce Fos and related proteins in rat striatal neurons. Neuroscience 37 (1990) 287-294
21. Figueredo-Cardenas G., Anderson K.D., Chen Q., Veenman C.L., and Reiner A. Relative survival of striatal projection neurons and interneurons after intrastriatal injection of quinolinic acid in rats. Exp. Neurol. 129 (1994) 37-56
22. Fusco F.R., Chen Q., Lamoreaux W.J., Figueredo-Cardenas G., Jiao Y., Coffman J.A., Surmeier D.J., Honig M.G., Carlock L.R., and Reiner A. Cellular localization of Huntington in striatal and cortical neurons in rats: lack of correlation with neuronal vulnerability in Huntington's disease. J. Neurosci. 19 (1999) 1189-1202
23. Gerfen C.R. Molecular effects of dopamine on striatal-projection pathways. Trends Neurosci. 23 (2000) 64-70
24. Gerfen C.R., and Young W.S. Distribution of striato-nigral and striato-pallidal peptidergic neurons in both patch and matrix compartments: an in situ hybridization histochemistry and fluorescence retrograde tracing study. Brain Res. 460 (1988) 161-167
25. Gerfen C.R., Engber T.M., Mahan L.C., Susel Z., Chase T.N., Monsma F.J., and Sibley D.R. D1 and D2 dopamine receptor-regulated gene expression of striato-nigral and striato-pallidal neurons. Science 250 (1990) 1429-1432
26. Gerfen C.R., Keefe K.A., and Gauda E.B. D1 and D2 dopamine receptor function in the striatum: coactivation of D1- and D2-dopamine receptors on separate populations of neurons results in potentiated immediate early gene response in D1-containing neurons. J. Neurosci. 15 (1995) 8167-8176
27. Gnanalingham K.K., Smith L.A., Hunter A.J., Jenner P., and Marsden C.D. Alteration in striatal and extrastriatal D1 and D2 dopamine receptors in the MPTP-treated Common Marmoset. An autoradiographic study. Synapse 14 (1993) 184-194
28. Grondin R., Goulet M., Morisette M., Bedard P.J., and Di Paolo T. Dopamine D1 receptor mRNA and receptor levels in the striatum of MPTP monkeys chronically treated with SKF-82958. Eur. J. Pharmacol. 378 (1999) 259-263
29. Harrison M.B., Wiley R.G., and Wooten G.F. Selective localization of striatal D1 receptors to striato-nigral neurons. Brain Res. 528 (1990) 317-322
30. Harrison M.B., Wiley R.G., and Wooten G.F. Changes in D2 but not D1 receptor binding in the striatum following a selective lesion of striato-pallidal neurons. Brain Res. 590 (1992) 305-310
31. 2+ conductance. J. Neurosci. 17 (1997) 3334-3342
32. 2+ currents and excitability via a novel PLC beta1-IP3-calcineuron-signaling cascade. J. Neurosci. 20 (2000) 8987-8995
33. Hersch S.M., Ciliax B.J., Gutekunst C.A., Rees H.D., Heilman C.J., Yung K.K., Bolam J.P., Ince E., Yi H., and Levey A.I. Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents. J. Neurosci. 15 (1995) 5222-5237
34. Huang Q., Zhou D., Chase K., Gusella J.F., Aronin N., and DiFiglia M. Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and post-synaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 11988-11992
35. Ince E., Ciliax B.J., and Levey A.I. Differential expression of D1 and D2 dopamine and m4 muscarinic acetylcholine receptor proteins in identified striato-nigral neurons. Synapse 27 (1997) 357-366
36. Kawaguchi Y., Wilson C.J., and Emson P.C. Projection subtypes of rat neostriatal matrix cells revealed by intracellular injection of biocytin. J. Neurosci. 10 (1990) 3421-3438
37. Kebabian J.W., and Calne D.B. Multiple receptors for dopamine. Nature 277 (1979) 93-96
38. Kebabian J.W., Petzgold G.L., and Greengard P. Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor". Proc. Natl. Acad. Sci. U.S.A. 69 (1972) 2145-2149
39. Keefe K.A., and Gerfen C.R. D1-D2 dopamine receptor synergy in striatum: effects of intrastriatal infusions of dopamine agonists and antagonists on immediate early gene expression. Neuroscience 66 (1995) 903-913
40. Kotecha S.A., Oak J.N., Jackson M.F., Perez Y., Orser B.A., Van Tol H.H.M., and MacDonald J.F. A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission. Neuron 35 (2002) 111-1122
41. Larson E.R., and Ariano M.A. Dopamine receptor binding on identified striato-nigral neurons. Neurosci. Lett. 172 (1994) 101-106
42. Lei W.L., Jiao Y., Del Mar N., and Reiner A. Evidence for differential cortical input to direct pathway versus indirect pathway striatal projection neurons in rats. J. Neurosci. 24 (2004) 8289-8299
43. Le Moine C., and Bloch B. D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum. J. Comp. Neurol. 355 (1995) 418-426
44. Le Moine C., Normand E., and Bloch B. Phenotypical characterization of the rat striatal neurons expressing the D1 dopamine receptor gene. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 4205-4209
45. Le Moine C., Normand E., Guitteny A.F., Fouque B., Teoule R., and Bloch B. Dopamine receptor gene expression by enkephalin neurons in rat forebrain. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 230-234
46. Lester J., Fink S., Aronin N., and DiFiglia M. Colocalization of D1 and D2 dopamine receptor mRNAs in striatal neurons. Brain Res. 621 (1993) 106-110
47. Lévesque M., and Parent A. The striato-fugal fiber system in primates: a reevaluation of its organization based on single-axon tracing studies. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 11888-11893
48. Levey A.I., Hersch S.M., Rye D.B., Sunahara R.K., Niznik H.B., Kitt C.A., Price D.L., Maggio R., Brann M.R., and Ciliax B.J. Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 8861-8865
49. MacLennan A.J., Lee N., Vincent S.R., and Walker D.W. D2 dopamine receptor mRNA distribution in cholinergic and somatostatinergic cells of the rat caudate-putamen and nucleus accumbens. Neurosci. Lett. 180 (1994) 214-218
50. McVittie L., Ariano M., and Sibley D. Characterization of anti-peptide antibodies for the localization of D2 dopamine receptors in rat striatum. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 1441-1445
51. Meade C.A., Deng Y.P., Fusco F.R., Del Mar N., Hersch S., Goldowitz D., and Reiner A. Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice. J. Comp. Neurol. 449 (2002) 241-269
52. Meade C.A., Figueredo-Cardenas G., Fusco F., Nowak Jr. T.S., Pulsinelli W.A., and Reiner A. Transient global ischemia in rats yields striatal projection neuron and interneuron loss resembling that in Huntington's disease. Exp. Neurol. 166 (2000) 307-323
53. Meador-Woodruff J.H., Mansour A., Healy D.J., Kuehn R., Zhou Q.Y., Bunzow J.R., Akil H., Civelli O., and Watson S.J. Comparison of distributions of D1 and D2 dopamine receptor mRNAs in rat brain. Neuropsychopharmacology 5 (1991) 231-242
54. Mengod G., Martinez-Mir M.I., Vilaro M.T., and Palacios J.M. Localization of the mRNA for the dopamine D2 receptor in the rat brain by in situ hybridization histochemistry. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 8560-8564
55. Mitchell I.J., Clarke C.E., Boyce S., Robertson R.G., Peggs D., Sambrook M.A., and Crossman A.R. Neural mechanisms underlying Parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience 32 (1989) 213-226
56. Mullen R.J., Buck C.R., and Smith A.M. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116 (1992) 201-211
57. Ono M., Murakami T., Kudo A., Ishiki M., Sawada H., and Segawa A. Quantitative comparison of anti-fading mounting media for confocal laser scanning microscopy. J. Histochem. Cytochem. 49 (2001) 305-311
58. Panchuk-Voloshina N., Haugland R.P., Bishop-Stewart J., Bhalgat M.K., Millard P.J., Mao F., Leung W.Y., and Haugland R.P. Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates. J. Histochem. Cytochem. 47 (1999) 1179-1188
59. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 4th ed. (1998), Academic Press, New York
60. Reiner A., and Anderson K.D. The patterns of neurotransmitter and neuropeptide co-occurrence among striatal projection neurons: conclusions based on recent findings. Brain Res. Rev. 15 (1990) 251-265
61. Reiner A., Medina L., and Haber S.N. The distribution of dynorphinergic terminals in striatal target regions in comparison to the distribution of substance P-containing and enkephalinergic terminals in monkeys and humans. Neuroscience 88 (1999) 775-793
62. Reiner A., Veenman C.L., Medina L., Jiao Y., Del Mar N., and Honig M.G. Pathway tracing using biotinylated dextran amines. J. Neurosci. Methods 103 (2000) 23-37
63. Richfield E.K., Young A.B., and Penney J.B. Comparative distribution of D1 and D2 receptors in the basal ganglia of turtles, pigeons, rats, cats and monkeys. J. Comp. Neurol. 262 (1987) 446-463
64. Robertson G.S., Vincent S.R., and Fibiger H.C. D1 and D2 dopamine receptors differentially regulate c-fos expression in striato-nigral and striato-pallidal neurons. Neuroscience 49 (1992) 285-296
65. Sesack S., Aoki C., and Pickel V. Ultrastructural localization of D2 receptor-like immunoreactivity in midbrain dopamine neurons and their striatal targets. J. Neurosci. 14 (1994) 88-106
66. Sibley D.R. Cloning of a "D3" receptor subtype expands dopamine receptor family. Trends Pharmacol. Sci. 12 (1991) 7-9
67. Soghomonian J.J., and Chesselet M.F. Effects of nigrostriatal lesions on the levels of messenger RNAs encoding two isoforms of glutamate decarboxylase in the globus pallidus and entopeduncular nucleus of the rat. Synapse 11 (1992) 124-133
68. Sugimoto T., and Mizuno N. Neurotensin in projection neurons of the striatum and nucleus accumbens, with reference to co-existence with enkephalin and GABA: an immunohistochemical study in the cat. J. Comp. Neurol. 257 (1987) 383-395
69. Sunahara R.K., Guan H.C., O'Dowd B.F., Seeman P., Laurier L.G., Ng G., George S.R., Torchia J., Van Tol H.M.M., and Niznik H.B. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature 350 (1991) 614-619
70. Surmeier D.J., Eberwine J., Wilson C.J., Cao Y., Stefani A., and Kitai S.T. Dopamine receptor subtypes colocalize in rat striato-nigral neurons. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 10178-10182
71. Surmeier D.J., Reiner A., Levine M.S., and Ariano M.A. Are neostriatal dopamine receptors co-localized?. Trends Neurosci. 16 (1993) 299-305
72. Surmeier D.J., Song W.J., and Yan Z. Coordinated expression of dopamine receptors in neostriatal medium spiny neurons. J. Neurosci. 16 (1996) 6579-6591
73. Umemiya M., and Raymond L.A. Dopaminergic modulation of excitatory post-synaptic currents in rat neostriatal neurons. J. Neurophysiol. 78 (1997) 1248-1255
74. Van Tol H.H.M., Bunzow J.R., Guan H.C., Sunahara R.K., Seeman P., Niznik H.B., and Civelli O. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature 350 (1991) 610-614
75. Vila M., Levy R., Herrero M.T., Ruberg M., Faucheux B., Obeso J.A., Agid Y., and Hirsch E.C. Consequences of nigrostriatal denervation on the functioning of the basal ganglia in human and non-human primates: an in situ hybridization study of cytochrome oxidase subunit I mRNA. J. Neurosci. 17 (1997) 765-773
76. Wang H.B., Laverghetta A.V., Foehring R., Deng Y.P., Sun Z., Yamamoto K., Lei W.L., Jiao Y., and Reiner A. Single-cell RT-PCR, in situ hybridization histochemical, and immunohistochemical studies of substance P and enkephalin co-occurrence in striatal projection neurons in rats. J. Chem. Neuroanat. 31 (2006) 178-199
77. Wang H., and Pickel V.M. Dopamine D2 receptors are present in prefrontal cortical afferents and their targets in patches of the rat caudate-putamen nucleus. J. Comp. Neurol. 442 (2002) 392-404
78. Waszczak B.L., Martin L.P., Greif G.J., and Freedman J.E. Expression of a dopamine D2 receptor-activated K+ channel on identified striato-pallidal and striato-nigral neurons. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 11440-11444
79. Weiner D.M., Levey A.I., and Brann M.R. Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 7050-7054
80. Weiner D.M., Levey A.I., Sunahara R.K., Niznik H.B., O'Dowd B.F., Seeman P., and Brann M.R. D1 and D2 dopamine receptor mRNA in rat brain. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 1859-1863
81. Wu Y., Richard S., and Parent A. The organization of the striatal output system: a single-cell juxtacellular labeling study in the rat. Neurosci. Res. 38 (2000) 49-62
82. Yung K.K., Bolam J.P., Smith A.D., Hersch S.M., Ciliax B.J., and Levey A.I. Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy. Neuroscience 65 (1995) 709-730