Deciphering the stromal and hematopoietic cell network of the adventitia from non-aneurysmal and aneurysmal human aorta

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Dutertre, Charles Antoine ^a,f   Clement, Marc ^a,b   Morvan, Marion ^a   Schäkel, Knut ^c   Castier, Yves ^a,b   Alsac, Jean Marc ^d   Michel, Jean Baptiste ^a,b,e   Nicoletti, Antonino ^a,b,e  

^a BICHAT HOSPITAL   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^d HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^e Dé Partement Hospitalo Universitaire FIRE   (France)

^f DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AORTA ANEURYSM; AORTA WALL; ARTERY DIAMETER; ARTICLE; CELL COMPOSITION; CELL PROLIFERATION; CELL SUBPOPULATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH VESSEL; LYMPHOID ORGAN; MACROPHAGE; MALE; MIDDLE AGED; STEADY STATE; STROMA CELL; T LYMPHOCYTE;

ADVENTITIA; AORTIC ANEURYSM; HUMANS; IMMUNOPHENOTYPING; LEUKOCYTES; STROMAL CELLS;

EID: 84896115000     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089983     Document Type: Article

References (48)

1. Michel JB, Thaunat O, Houard X, Meilhac O, Caligiuri G, et al. (2007) Topological determinants and consequences of adventitial responses to arterial wall injury. Arterioscler Thromb Vasc Biol 27: 1259-1268. (Pubitemid 46809413)
2. Koch AE, Haines GK, Rizzo RJ, Radosevich JA, Pope RM, et al. (1990) Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response. Am J Pathol 137: 1199-1213.
3. Schwartz CJ and Mitchell JR (1962) Cellular infiltration of the human arterial adventitia associated with atheromatous plaques. Circulation 26: 73-78.
4. Saphir O and Gore I (1950) Evidence for an inflammatory basis of coronary arteriosclerosis in the young. Arch Pathol 48: 9.
5. Galkina E, Kadl A, Sanders J, Varughese D, Sarembock IJ, et al. (2006) Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J Exp Med 203: 1273-1282. (Pubitemid 43736596)
6. Grabner R, Lotzer K, Dopping S, Hildner M, Radke D, et al. (2009) Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. J Exp Med 206: 233-248.
7. Houtkamp MA, de Boer OJ, van der Loos CM, van der Wal AC and Becker AE (2001) Adventitial infiltrates associated with advanced atherosclerotic plaques: structural organization suggests generation of local humoral immune responses. J Pathol 193: 263-269. (Pubitemid 32118139)
8. Moos MP, John N, Grabner R, Nossmann S, Gunther B, et al. (2005) The lamina adventitia is the major site of immune cell accumulation in standard chow-fed apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 25: 2386-2391. (Pubitemid 41552659)
9. Bobryshev YV and Lord RS (2001) Vascular-associated lymphoid tissue (VALT) involvement in aortic aneurysm. Atherosclerosis 154: 15-21. (Pubitemid 32008559)
10. Aloisi F and Pujol-Borrell R (2006) Lymphoid neogenesis in chronic inflammatory diseases. Nat Rev Immunol 6: 205-217. (Pubitemid 43290990)
11. Campbell KA, Lipinski MJ, Doran AC, Skaflen MD, Fuster V, et al. (2012) Lymphocytes and the adventitial immune response in atherosclerosis. Circ Res 110: 889-900.
12. Cupedo T and Mebius RE (2003) Role of chemokines in the development of secondary and tertiary lymphoid tissues. Semin Immunol 15: 243-248. (Pubitemid 38156052)
13. Fletcher AL, Lukacs-Kornek V, Reynoso ED, Pinner SE, Bellemare-Pelletier A, et al. (2010) Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med 207: 689-697.
14. Fletcher AL, Malhotra D, Acton SE, Lukacs-Kornek V, Bellemare-Pelletier A, et al. (2011) Reproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cells. Front Immunol 2: 35.
15. Mantovani A, Garlanda C and Locati M (2009) Macrophage diversity and polarization in atherosclerosis: a question of balance. Arterioscler Thromb Vasc Biol 29: 1419-1423.
16. Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, et al. (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25: 677-686. (Pubitemid 39457982)
17. Martinez FO, Helming L and Gordon S (2009) Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol 27: 451-483.
18. Schakel K, Kannagi R, Kniep B, Goto Y, Mitsuoka C, et al. (2002) 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells. Immunity 17: 289-301. (Pubitemid 35279550)
19. Dutertre CA, Amraoui S, Derosa A, Jourdain JP, Vimeux L, et al. (2012) Pivotal role of M-DC8 + monocytes from viremic HIV-infected patients in TNFalpha overproduction in response to microbial products. Blood 120: 2259-2268.
20. de Baey A, Mende I, Baretton G, Greiner A, Hartl WH, et al. (2003) A subset of human dendritic cells in the T cell area of mucosa-associated lymphoid tissue with a high potential to produce TNF-alpha. J Immunol 170: 5089-5094. (Pubitemid 36554739)
21. Schakel K, von Kietzell M, Hansel A, Ebling A, Schulze L, et al. (2006) Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes. Immunity 24: 767-777. (Pubitemid 43884896)
22. Hansel A, Gunther C, Ingwersen J, Starke J, Schmitz M, et al. (2011) Human slan (6-sulfo LacNAc) dendritic cells are inflammatory dermal dendritic cells in psoriasis and drive strong TH17/TH1 T-cell responses. J Allergy Clin Immunol 127: 787-794 e781-789.
23. Delbosc S, Diallo D, Dejouvencel T, Lamiral Z, Louedec L, et al. (2013) Impaired high-density lipoprotein anti-oxidant capacity in human abdominal aortic aneurysm. Cardiovasc Res 100: 307-315.
24. Fontaine V, Jacob MP, Houard X, Rossignol P, Plissonnier D, et al. (2002) Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms. Am J Pathol 161: 1701-1710. (Pubitemid 35265529)
25. Gil M, Park SJ, Chung YS and Park CS (2010) Interleukin-15 enhances proliferation and chemokine secretion of human follicular dendritic cells. Immunology 130: 536-544.
26. Gordon S (2003) Alternative activation of macrophages. Nat Rev Immunol 3: 23-35.
27. Zizzo G, Hilliard BA, Monestier M and Cohen PL (2012) Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction. J Immunol 189: 3508-3520.
28. Kolodgie FD, Narula J, Yuan C, Burke AP, Finn AV, et al. (2007) Elimination of neoangiogenesis for plaque stabilization: is there a role for local drug therapy? J Am Coll Cardiol 49: 2093-2101. (Pubitemid 46771051)
29. Maiellaro K and Taylor WR (2007) The role of the adventitia in vascular inflammation. Cardiovasc Res 75: 640-648. (Pubitemid 47238746)
30. Ho-Tin-Noe B and Michel JB (2011) Initiation of angiogenesis in atherosclerosis: smooth muscle cells as mediators of the angiogenic response to atheroma formation. Trends Cardiovasc Med 21: 183-187.
31. Zhao L, Moos MP, Grabner R, Pedrono F, Fan J, et al. (2004) The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm. Nat Med 10: 966-973. (Pubitemid 39273738)
32. Robbins CS, Hilgendorf I, Weber GF, Theurl I, Iwamoto Y, et al. (2013) Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat Med 19: 1166-1172.
33. Boytard L, Spear R, Chinetti-Gbaguidi G, Acosta-Martin AE, Vanhoutte J, et al. (2013) Role of proinflammatory CD68(+) mannose receptor(-) macrophages in peroxiredoxin-1 expression and in abdominal aortic aneurysms in humans. Arterioscler Thromb Vasc Biol 33: 431-438.
34. Lacolley P, Regnault V, Nicoletti A, Li Z and Michel JB (2012) The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles. Cardiovasc Res 95: 194-204.
35. Boyle JJ (2012) Heme and haemoglobin direct macrophage Mhem phenotype and counter foam cell formation in areas of intraplaque haemorrhage. Curr Opin Lipidol 23: 453-461.
36. Delbosc S, Alsac JM, Journe C, Louedec L, Castier Y, et al. (2011) Porphyromonas gingivalis participates in pathogenesis of human abdominal aortic aneurysm by neutrophil activation. Proof of concept in rats. PLoS One 6: e18679.
37. Galkina E and Ley K (2009) Immune and inflammatory mechanisms of atherosclerosis (*). Annu Rev Immunol 27: 165-197.
38. Combadiere C, Potteaux S, Gao JL, Esposito B, Casanova S, et al. (2003) Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation 107: 1009-1016. (Pubitemid 36258725)
39. Combadiere C, Potteaux S, Rodero M, Simon T, Pezard A, et al. (2008) Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice. Circulation 117: 1649-1657. (Pubitemid 351482605)
40. Patel A, Jagadesham VP, Porter KE, Scott DJ and Carding SR (2008) Characterisation of fractalkine/CX3CL1 and fractalkine receptor (CX3CR1) expression in abdominal aortic aneurysm disease. Eur J Vasc Endovasc Surg 36: 20-27. (Pubitemid 351877094)
41. Siedlar M, Frankenberger M, Ziegler-Heitbrock LH and Belge KU (2000) The M-DC8-positive leukocytes are a subpopulation of the CD14+ CD16+ monocytes. Immunobiology 202: 11-17. (Pubitemid 30323611)
42. Schakel K, Mayer E, Federle C, Schmitz M, Riethmuller G, et al. (1998) A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. Eur J Immunol 28: 4084-4093. (Pubitemid 28558638)
43. Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, et al. (2013) Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity 39: 599-610.
44. Hansel A, Gunther C, Baran W, Bidier M, Lorenz HM, et al. (2013) Human 6-sulfo LacNAc (slan) dendritic cells have molecular and functional features of an important pro-inflammatory cell type in lupus erythematosus. J Autoimmun 40: 1-8.
45. Kain MJ and Owens BM (2013) Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis. Immunology 140: 12-21.
46. Lotzer K, Dopping S, Connert S, Grabner R, Spanbroek R, et al. (2010) Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signaling. Arterioscler Thromb Vasc Biol 30: 395-402.
47. Jones JA, Beck C, Barbour JR, Zavadzkas JA, Mukherjee R, et al. (2009) Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling. Am J Pathol 175: 1746-1756.
48. Sakata N, Nabeshima K, Iwasaki H, Tashiro T, Uesugi N, et al. (2007) Possible involvement of myofibroblast in the development of inflammatory aortic aneurysm. Pathol Res Pract 203: 21-29. (Pubitemid 46118076)