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Volumn 8, Issue 3, 2014, Pages 282-288

Molecular characterization of extended-spectrum beta-lactamase producing Enterobacteriaceae in a Saudi Arabian tertiary hospital

Author keywords

CTX M; Enterobacteriaceae; ESBL

Indexed keywords

AMIKACIN; BETA LACTAMASE AMPC; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; CLAVULANIC ACID; COTRIMOXAZOLE; GENTAMICIN; PIPERACILLIN PLUS TAZOBACTAM;

EID: 84896098410     PISSN: 20366590     EISSN: 19722680     Source Type: Journal    
DOI: 10.3855/jidc.3809     Document Type: Article
Times cited : (52)

References (44)
  • 1
  • 3
    • 27144490073 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases: A clinical update
    • Paterson DL, Bonomo RA (2005) Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev 18: 657-686.
    • (2005) Clin Microbiol Rev , vol.18 , pp. 657-686
    • Paterson, D.L.1    Bonomo, R.A.2
  • 4
    • 33748678285 scopus 로고    scopus 로고
    • The CTX-M beta-lactamase pandemic
    • Canton R, Coque TM (2006) The CTX-M beta-lactamase pandemic. Curr Opin Microbiol 9: 466-475.
    • (2006) Curr Opin Microbiol , vol.9 , pp. 466-475
    • Canton, R.1    Coque, T.M.2
  • 5
    • 0347362476 scopus 로고    scopus 로고
    • Growing group of extended-spectrum beta-lactamases: The CTX-M enzymes
    • Bonnet R (2004) Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. Antimicrob Agents Chemother 48: 1-14.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 1-14
    • Bonnet, R.1
  • 6
    • 0034763241 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat
    • Bradford PA (2001) Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev 14: 933-951.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 933-951
    • Bradford, P.A.1
  • 7
    • 33645788333 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases and clinical outcomes: Current data
    • Ramphal R, Ambrose PG (2006) Extended-spectrum beta-lactamases and clinical outcomes: current data. Clin Infect Dis 42 Suppl 4: S164-172.
    • (2006) Clin Infect Dis , vol.42 , Issue.SUPPL. 4
    • Ramphal, R.1    Ambrose, P.G.2
  • 8
    • 10744220770 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases: Implications for the clinical microbiology laboratory, therapy, and infection control
    • Sturenburg E, Mack D (2003) Extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory, therapy, and infection control. J Infect 47: 273-295.
    • (2003) J Infect , vol.47 , pp. 273-295
    • Sturenburg, E.1    Mack, D.2
  • 9
    • 0034048070 scopus 로고    scopus 로고
    • Detection of extended-spectrum beta-lactamases in members of the family enterobacteriaceae: Comparison of the MAST DD test, the double disc and the Etest ESBL
    • M'Zali FH, Chanawong A, Kerr KG, Birkenhead D, Hawkey PM (2000) Detection of extended-spectrum beta-lactamases in members of the family enterobacteriaceae: comparison of the MAST DD test, the double disc and the Etest ESBL. J Antimicrob Chemother 45: 881-885.
    • (2000) J Antimicrob Chemother , vol.45 , pp. 881-885
    • M'Zali, F.H.1    Chanawong, A.2    Kerr, K.G.3    Birkenhead, D.4    Hawkey, P.M.5
  • 10
    • 3843054730 scopus 로고    scopus 로고
    • Use of DNA microarrays for rapid genotyping of TEM beta-lactamases that confer resistance
    • Grimm V, Ezaki S, Susa M, Knabbe C, Schmid RD, Bachmann TT (2004) Use of DNA microarrays for rapid genotyping of TEM beta-lactamases that confer resistance. J Clin Microbiol 42: 3766-3774.
    • (2004) J Clin Microbiol , vol.42 , pp. 3766-3774
    • Grimm, V.1    Ezaki, S.2    Susa, M.3    Knabbe, C.4    Schmid, R.D.5    Bachmann, T.T.6
  • 11
    • 78349275358 scopus 로고    scopus 로고
    • Evaluation of a chromogenic agar medium for the detection of extended-spectrum ss-lactamase-producing Enterobacteriaceae
    • Saito R, Koyano S, Nagai R, Okamura N, Moriya K, Koike K (2010) Evaluation of a chromogenic agar medium for the detection of extended-spectrum ss-lactamase-producing Enterobacteriaceae. Lett Appl Microbiol 51: 704-706.
    • (2010) Lett Appl Microbiol , vol.51 , pp. 704-706
    • Saito, R.1    Koyano, S.2    Nagai, R.3    Okamura, N.4    Moriya, K.5    Koike, K.6
  • 12
    • 32044432836 scopus 로고    scopus 로고
    • Prevalence of extended-spectrum beta-lactamases among Enterobacteriaceae isolated from blood culture in a tertiary care hospital
    • El-Khizzi NA, Bakheshwain SM (2006) Prevalence of extended-spectrum beta-lactamases among Enterobacteriaceae isolated from blood culture in a tertiary care hospital. Saudi Med J 27: 37-40.
    • (2006) Saudi Med J , vol.27 , pp. 37-40
    • El-Khizzi, N.A.1    Bakheshwain, S.M.2
  • 13
    • 22544439657 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases in urinary isolates of Escherichia coli, Klebsiella pneumoniae and other gram-negative bacteria in a hospital in Eastern Province, Saudi Arabia
    • Kader AA, Angamuthu K (2005) Extended-spectrum beta-lactamases in urinary isolates of Escherichia coli, Klebsiella pneumoniae and other gram-negative bacteria in a hospital in Eastern Province, Saudi Arabia. Saudi Med J 26: 956-959.
    • (2005) Saudi Med J , vol.26 , pp. 956-959
    • Kader, A.A.1    Angamuthu, K.2
  • 14
    • 34548339667 scopus 로고    scopus 로고
    • Fecal carriage of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in patients and asymptomatic healthy individuals
    • Kader AA, Kumar A, Kamath KA (2007) Fecal carriage of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in patients and asymptomatic healthy individuals. Infect Control Hosp Epidemiol 28: 1114-1116.
    • (2007) Infect Control Hosp Epidemiol , vol.28 , pp. 1114-1116
    • Kader, A.A.1    Kumar, A.2    Kamath, K.A.3
  • 15
    • 13844254107 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae hospital acquired bacteremia. Risk factors and clinical outcome
    • Panhotra BR, Saxena AK, Al-Ghamdi AM (2004) Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae hospital acquired bacteremia. Risk factors and clinical outcome. Saudi Med J 25:.1871-1876
    • (2004) Saudi Med J , vol.25 , pp. 1871-1876
    • Panhotra, B.R.1    Saxena, A.K.2    Al-Ghamdi, A.M.3
  • 16
    • 80052216619 scopus 로고    scopus 로고
    • Prevalence and genetic characteristics of TEM, SHV, and CTX-M in clinical Klebsiella pneumoniae isolates from Saudi Arabia
    • Tawfik AF, Alswailem AM, Shibl AM, Al-Agamy MH (2011) Prevalence and genetic characteristics of TEM, SHV, and CTX-M in clinical Klebsiella pneumoniae isolates from Saudi Arabia. Microb Drug Resist 17: 383-388.
    • (2011) Microb Drug Resist , vol.17 , pp. 383-388
    • Tawfik, A.F.1    Alswailem, A.M.2    Shibl, A.M.3    Al-Agamy, M.H.4
  • 17
    • 70149107336 scopus 로고    scopus 로고
    • Prevalence and molecular characterization of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in Riyadh, Saudi Arabia
    • Al-Agamy MH, Shibl AM, Tawfik AF (2009) Prevalence and molecular characterization of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in Riyadh, Saudi Arabia. Ann Saudi Med 29: 253-257.
    • (2009) Ann Saudi Med , vol.29 , pp. 253-257
    • Al-Agamy, M.H.1    Shibl, A.M.2    Tawfik, A.F.3
  • 18
    • 0029953215 scopus 로고    scopus 로고
    • Detection of extended-spectrum beta-lactamase (ESBL)-producing strains by the Etest ESBL screen
    • Cormican MG, Marshall SA, Jones RN (1996) Detection of extended-spectrum beta-lactamase (ESBL)-producing strains by the Etest ESBL screen. J Clin Microbiol 34: 1880-1884.
    • (1996) J Clin Microbiol , vol.34 , pp. 1880-1884
    • Cormican, M.G.1    Marshall, S.A.2    Jones, R.N.3
  • 19
    • 84875216191 scopus 로고    scopus 로고
    • Evaluation of three selective chromogenic media, CHROMagar ESBL, CHROMagar CTX-M and CHROMagar KPC, for the detection of Klebsiella pneumoniae producing OXA-48 carbapenemase
    • Hornsey M, Phee L, Woodford N, Turton J, Meunier D, Thomas C, Wareham DW (2013) Evaluation of three selective chromogenic media, CHROMagar ESBL, CHROMagar CTX-M and CHROMagar KPC, for the detection of Klebsiella pneumoniae producing OXA-48 carbapenemase. J Clin Pathol 66: 348-350.
    • (2013) J Clin Pathol , vol.66 , pp. 348-350
    • Hornsey, M.1    Phee, L.2    Woodford, N.3    Turton, J.4    Meunier, D.5    Thomas, C.6    Wareham, D.W.7
  • 20
    • 0031860676 scopus 로고    scopus 로고
    • beta-Lactamases responsible for resistance to expanded-spectrum cephalosporins in Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis isolates recovered in South Africa
    • Pitout JD, Thomson KS, Hanson ND, Ehrhardt AF, Moland ES, Sanders CC (1998) beta-Lactamases responsible for resistance to expanded-spectrum cephalosporins in Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis isolates recovered in South Africa. Antimicrob Agents Chemother 42: 1350-1354.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1350-1354
    • Pitout, J.D.1    Thomson, K.S.2    Hanson, N.D.3    Ehrhardt, A.F.4    Moland, E.S.5    Sanders, C.C.6
  • 21
    • 58849120520 scopus 로고    scopus 로고
    • Evaluation of CHROMagar CTX, a novel medium for isolating CTX-M-ESBL-positive Enterobacteriaceae while inhibiting AmpC-producing strains
    • Randall LP, Kirchner M, Teale CJ, Coldham NG, Liebana E, Clifton-Hadley F (2009) Evaluation of CHROMagar CTX, a novel medium for isolating CTX-M-ESBL-positive Enterobacteriaceae while inhibiting AmpC-producing strains. J Antimicrob Chemother 63: 302-308.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 302-308
    • Randall, L.P.1    Kirchner, M.2    Teale, C.J.3    Coldham, N.G.4    Liebana, E.5    Clifton-Hadley, F.6
  • 22
    • 0242322614 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: Dominance and widespread prevalence of SHV-and CTX-M-type beta-lactamases
    • International Klebsiella Study Group
    • Paterson DL, Hujer KM, Hujer AM, Yeiser B, Bonomo MD, Rice LB, Bonomo RA, International Klebsiella Study Group (2003) Extended-spectrum beta-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV-and CTX-M-type beta-lactamases. Antimicrob Agents Chemother 47: 3554-3560.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 3554-3560
    • Paterson, D.L.1    Hujer, K.M.2    Hujer, A.M.3    Yeiser, B.4    Bonomo, M.D.5    Rice, L.B.6    Bonomo, R.A.7
  • 23
    • 30344458493 scopus 로고    scopus 로고
    • Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases
    • Woodford N, Fagan EJ, Ellington MJ (2006) Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases. J Antimicrob Chemother 57: 154-155.
    • (2006) J Antimicrob Chemother , vol.57 , pp. 154-155
    • Woodford, N.1    Fagan, E.J.2    Ellington, M.J.3
  • 24
    • 70249109242 scopus 로고    scopus 로고
    • Salmonella enterica serovar Typhi with CTX-M beta-lactamase, Germany
    • Pfeifer Y, Matten J, Rabsch W (2009) Salmonella enterica serovar Typhi with CTX-M beta-lactamase, Germany. Emerg Infect Dis 15: 1533-1535.
    • (2009) Emerg Infect Dis , vol.15 , pp. 1533-1535
    • Pfeifer, Y.1    Matten, J.2    Rabsch, W.3
  • 25
    • 23844448752 scopus 로고    scopus 로고
    • Molecular characterization of TEM-and SHV-derived extended-spectrum beta-lactamases in hospital-based Enterobacteriaceae in Turkey
    • Huseyin T, Hakki B (2005) Molecular characterization of TEM-and SHV-derived extended-spectrum beta-lactamases in hospital-based Enterobacteriaceae in Turkey. Jpn J Infect Dis 58: 162-167.
    • (2005) Jpn J Infect Dis , vol.58 , pp. 162-167
    • Huseyin, T.1    Hakki, B.2
  • 26
    • 1542358882 scopus 로고    scopus 로고
    • Methodology in diagnostic laboratory test research in clinical chemistry and clinical chemistry and laboratory medicine
    • Lumbreras-Lacarra B, Ramos-Rincón JM, Hernández-Aguado I (2004). Methodology in diagnostic laboratory test research in clinical chemistry and clinical chemistry and laboratory medicine. Clin Chem 50: 530-536.
    • (2004) Clin Chem , vol.50 , pp. 530-536
    • Lumbreras-Lacarra, B.1    Ramos-Rincón, J.M.2    Hernández-Aguado, I.3
  • 27
    • 37249088843 scopus 로고    scopus 로고
    • Prevalence and clonality of extended-spectrum beta-lactamases in Asia
    • Hawkey PM (2008) Prevalence and clonality of extended-spectrum beta-lactamases in Asia. Clin Microbiol Infect 14 Suppl 1: 159-165.
    • (2008) Clin Microbiol Infect , vol.14 , Issue.SUPPL. 1 , pp. 159-165
    • Hawkey, P.M.1
  • 30
    • 36749013015 scopus 로고    scopus 로고
    • Prevalence and antimicrobial susceptibility pattern of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the United Arab Emirates
    • Al-Zarouni M, Senok A, Rashid F, Al-Jesmi SM, Panigrahi D (2008) Prevalence and antimicrobial susceptibility pattern of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the United Arab Emirates. Med Princ Pract 17: 32-36.
    • (2008) Med Princ Pract , vol.17 , pp. 32-36
    • Al-Zarouni, M.1    Senok, A.2    Rashid, F.3    Al-Jesmi, S.M.4    Panigrahi, D.5
  • 31
    • 52349096466 scopus 로고    scopus 로고
    • The technical aspects and clinical significance of detecting extended-spectrum beta-lactamase-producing Enterobacteriaceae at a tertiary-care hospital in Kuwait
    • Mokaddas EM, Abdulla AA, Shati S, Rotimi VO (2008) The technical aspects and clinical significance of detecting extended-spectrum beta-lactamase-producing Enterobacteriaceae at a tertiary-care hospital in Kuwait. J Chemother 20: 445-451.
    • (2008) J Chemother , vol.20 , pp. 445-451
    • Mokaddas, E.M.1    Abdulla, A.A.2    Shati, S.3    Rotimi, V.O.4
  • 33
    • 67649484680 scopus 로고    scopus 로고
    • Extended spectrum beta-lactamases (ESBL) in Escherichia coli and Klebsiella pneumoniae: Trends in the hospital and community settings
    • doi:10.3855/jidc.127
    • Khanfar HS, Bindayna KM, Senok AC, Botta GA (2009) Extended spectrum beta-lactamases (ESBL) in Escherichia coli and Klebsiella pneumoniae: trends in the hospital and community settings. J Infect Dev Ctries 3: 295-299. doi:10.3855/jidc.127
    • (2009) J Infect Dev Ctries , vol.3 , pp. 295-299
    • Khanfar, H.S.1    Bindayna, K.M.2    Senok, A.C.3    Botta, G.A.4
  • 34
    • 0033806947 scopus 로고    scopus 로고
    • Clinical and community strains of Klebsiella pneumoniae: Multiple and increasing rates of antibiotic resistance in Abha, Saudi Arabia
    • Bilal NE, Gedebou M (2000) Clinical and community strains of Klebsiella pneumoniae: multiple and increasing rates of antibiotic resistance in Abha, Saudi Arabia. Br J Biomed Sci 57: 185-191.
    • (2000) Br J Biomed Sci , vol.57 , pp. 185-191
    • Bilal, N.E.1    Gedebou, M.2
  • 35
    • 21844435993 scopus 로고    scopus 로고
    • Prevalence and antimicrobial susceptibility of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a general hospital
    • Kader AA, Kumar A (2005) Prevalence and antimicrobial susceptibility of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a general hospital. Ann Saudi Med 25: 239-242.
    • (2005) Ann Saudi Med , vol.25 , pp. 239-242
    • Kader, A.A.1    Kumar, A.2
  • 36
    • 79952365502 scopus 로고    scopus 로고
    • CTX-M-15-producing Escherichia coli clinical isolates in Cairo (Egypt), including isolates of clonal complex ST10 and clones ST131, ST73, and ST405 in both community and hospital settings
    • Fam N, Leflon-Guibout V, Fouad S, Aboul-Fadl L, Marcon E, Desouky D, El-Defrawy I, Abou-Aitta A, Klena J, Nicolas-Chanoine MH (2011) CTX-M-15-producing Escherichia coli clinical isolates in Cairo (Egypt), including isolates of clonal complex ST10 and clones ST131, ST73, and ST405 in both community and hospital settings. Microb Drug Resist 17: 67-73.
    • (2011) Microb Drug Resist , vol.17 , pp. 67-73
    • Fam, N.1    Leflon-Guibout, V.2    Fouad, S.3    Aboul-Fadl, L.4    Marcon, E.5    Desouky, D.6    El-Defrawy, I.7    Abou-Aitta, A.8    Klena, J.9    Nicolas-Chanoine, M.H.10
  • 37
    • 36148957875 scopus 로고    scopus 로고
    • Distribution of TEM and SHV beta-lactamase genes among Klebsiella pneumoniae strains isolated from patients in Tehran
    • Shahcheraghi F, Moezi H, Feizabadi MM (2007) Distribution of TEM and SHV beta-lactamase genes among Klebsiella pneumoniae strains isolated from patients in Tehran. Med Sci Monit 13: BR247-250.
    • (2007) Med Sci Monit , vol.13
    • Shahcheraghi, F.1    Moezi, H.2    Feizabadi, M.M.3
  • 38
    • 77958505196 scopus 로고    scopus 로고
    • Predominance of CTX-M genotype among extended spectrum beta lactamase isolates in a tertiary hospital in Saudi Arabia
    • Bindayna K, Khanfar HS, Senok AC, Botta GA (2010) Predominance of CTX-M genotype among extended spectrum beta lactamase isolates in a tertiary hospital in Saudi Arabia. Saudi Med J 31: 859-863.
    • (2010) Saudi Med J , vol.31 , pp. 859-863
    • Bindayna, K.1    Khanfar, H.S.2    Senok, A.C.3    Botta, G.A.4
  • 40
    • 62949241988 scopus 로고    scopus 로고
    • Predominance of CTX-M-15 extended spectrum beta-lactamases in diverse Escherichia coli and Klebsiella pneumoniae from hospital and community patients in Kuwait
    • Ensor VM, Jamal W, Rotimi VO, Evans JT, Hawkey PM (2009) Predominance of CTX-M-15 extended spectrum beta-lactamases in diverse Escherichia coli and Klebsiella pneumoniae from hospital and community patients in Kuwait. Int J Antimicrob Agents 33: 487-489.
    • (2009) Int J Antimicrob Agents , vol.33 , pp. 487-489
    • Ensor, V.M.1    Jamal, W.2    Rotimi, V.O.3    Evans, J.T.4    Hawkey, P.M.5
  • 41
    • 33646821688 scopus 로고    scopus 로고
    • First description of CTX-M beta-lactamase-producing clinical Escherichia coli isolates from Egypt
    • Mohamed Al-Agamy MH, El-Din Ashour MS, Wiegand I (2006) First description of CTX-M beta-lactamase-producing clinical Escherichia coli isolates from Egypt. Int J Antimicrob Agents 27: 545-548.
    • (2006) Int J Antimicrob Agents , vol.27 , pp. 545-548
    • Mohamed Al-Agamy, M.H.1    El-Din Ashour, M.S.2    Wiegand, I.3
  • 42
    • 77952968843 scopus 로고    scopus 로고
    • Transmission of a Klebsiella pneumoniae clone harbouring genes for CTX-M-15-like and SHV-112 enzymes in a neonatal intensive care unit of a Kuwaiti hospital
    • Dashti AA, Jadaon MM, Gomaa HH, Noronha B, Udo EE (2010) Transmission of a Klebsiella pneumoniae clone harbouring genes for CTX-M-15-like and SHV-112 enzymes in a neonatal intensive care unit of a Kuwaiti hospital. J Med Microbiol 59: 687-692.
    • (2010) J Med Microbiol , vol.59 , pp. 687-692
    • Dashti, A.A.1    Jadaon, M.M.2    Gomaa, H.H.3    Noronha, B.4    Udo, E.E.5
  • 43
    • 55849128106 scopus 로고    scopus 로고
    • Extended-spectrum Beta-lactamase detection with different panels for automated susceptibility testing and with a chromogenic medium
    • Farber J, Moder KA, Layer F, Tammer I, Konig W, Konig B (2008) Extended-spectrum Beta-lactamase detection with different panels for automated susceptibility testing and with a chromogenic medium. J Clin Microbiol 46: 3721-3727.
    • (2008) J Clin Microbiol , vol.46 , pp. 3721-3727
    • Farber, J.1    Moder, K.A.2    Layer, F.3    Tammer, I.4    Konig, W.5    Konig, B.6
  • 44
    • 0036791222 scopus 로고    scopus 로고
    • Evaluation of the Etest ESBL and the BD Phoenix, VITEK 1, and VITEK 2 automated instruments for detection of extended-spectrum beta-lactamases in multiresistant Escherichia coli and Klebsiella spp
    • Leverstein-van Hall MA, Fluit AC, Paauw A, Box AT, Brisse S, Verhoef J (2002) Evaluation of the Etest ESBL and the BD Phoenix, VITEK 1, and VITEK 2 automated instruments for detection of extended-spectrum beta-lactamases in multiresistant Escherichia coli and Klebsiella spp. J Clin Microbiol 40: 3703-3711.
    • (2002) J Clin Microbiol , vol.40 , pp. 3703-3711
    • Leverstein-van Hall, M.A.1    Fluit, A.C.2    Paauw, A.3    Box, A.T.4    Brisse, S.5    Verhoef, J.6


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