Cadherin-11 in renal cell carcinoma bone metastasis

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Satcher, Robert L ^a   Pan, Tianhong ^a   Cheng, Chien Jui ^b,c   Lee, Yu Chen ^a   Lin, Song Chang ^a   Yu, Guoyu ^a   Li, Xiaoxia ^a,d   Hoang, Anh G ^a   Tamboli, Pheroze ^a   Jonasch, Eric ^a   Gallick, Gary E ^a   Lin, Sue Hwa ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; CADHERIN; CADHERIN 11; CHEMOKINE RECEPTOR CXCR4; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; PARATHYROID HORMONE RELATED PROTEIN; SCATTER FACTOR RECEPTOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VASCULOTROPIN; CXCR4 PROTEIN, MOUSE; OSTEOBLAST CADHERIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE CELL; BONE METASTASIS; CANCER CELL; CELL ADHESION; CELL HOMING; CELL MIGRATION; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KIDNEY CARCINOMA; LIVER CELL; LYMPH NODE CELL; MALE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANIMAL; BONE TUMOR; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GENETICS; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SCID MOUSE; SECONDARY; TRANSPLANTATION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BONE NEOPLASMS; CADHERINS; CARCINOMA, RENAL CELL; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKDOWN TECHNIQUES; IMMUNOHISTOCHEMISTRY; MICE; MICE, SCID; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CXCR4; TUMOR CELLS, CULTURED;

EID: 84896089748     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089880     Document Type: Article

References (48)

1. Zekri J, Ahmed N, Coleman RE, Hancock BW (2001) The skeletal metastatic complications of renal cell carcinoma. Int J Oncol 19: 379-382.
2. Wood SL, Brown JE (2012) Skeletal metastasis in renal cell carcinoma: current and future management options. Cancer Treat Rev 38: 284-291.
3. Woodward E, Jagdev S, McParland L, Clark K, Gregory W, et al. (2011) Skeletal complications and survival in renal cancer patients with bone metastases. Bone 48: 160-166.
4. Motzer RJ, Russo P (2000) Systemic therapy for renal cell carcinoma. J Urol 163: 408-417. (Pubitemid 30060482)
5. Sahi C, Knox JJ, Clemons M, Joshua AM, Broom R (2010) Renal cell carcinoma bone metastases: clinical advances. Ther Adv Med Oncol 2: 75-83.
6. Xie C, Schwarz EM, Sampson ER, Dhillon RS, Li D, et al. (2012) Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression. J Orthop Res 30: 325-333.
7. Yamakawa M, Liu LX, Belanger AJ, Date T, Kuriyama T, et al. (2004) Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis. Am J Physiol Renal Physiol 287: F649-657. (Pubitemid 39280498)
8. Fidler IJ, Kripke ML (1977) Metastasis results from preexisting variant cells within a malignant tumor. Science 197: 893-895. (Pubitemid 8168759)
9. Fidler IJ (2003) The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 3: 453-458.
10. Okazaki M, Takeshita S, Kawai S, Kikuno R, Tsujimura A, et al. (1994) Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts. J Biol Chem 269: 12092-12098. (Pubitemid 24196706)
11. Cheng SL, Lecanda F, Davidson MK, Warlow PM, Zhang SF, et al. (1998) Human osteoblasts express a repertoire of cadherins, which are critical for BMP-2-induced osteogenic differentiation. J Bone Miner Res 13: 633-644. (Pubitemid 28163014)
12. Chu K, Cheng CJ, Ye X, Lee YC, Zurita AJ, et al. (2008) Cadherin-11 promotes the metastasis of prostate cancer cells to bone. Mol Cancer Res 6: 1259-1267.
13. Huang CF, Lira C, Chu K, Bilen MA, Lee YC, et al. (2010) Cadherin-11 increases migration and invasion of prostate cancer cells and enhances their interaction with osteoblasts. Cancer Res 70: 4580-4589.
14. Lee YC, Cheng CJ, Huang M, Bilen MA, Ye X, et al. (2010) Androgen depletion up-regulates cadherin-11 expression in prostate cancer. J Pathol 221: 68-76.
15. Tamura D, Hiraga T, Myoui A, Yoshikawa H, Yoneda T (2008) Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone. Int J Oncol 33: 17-24.
16. Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, et al. (2002) Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 62: 1832-1837. (Pubitemid 34408510)
17. Muller A, Homey B, Soto H, Ge N, Catron D, et al. (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-56. (Pubitemid 32225831)
18. Shiirevnyamba A, Takahashi T, Shan H, Ogawa H, Yano S, et al. (2011) Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts. Br J Cancer 104: 505-513.
19. Fizazi K, Yang J, Peleg S, Sikes CR, Kreimann EL, et al. (2003) Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts. Clin Cancer Res 9: 2587-2597. (Pubitemid 36842101)
20. Semenza G (2002) Signal transduction to hypoxia-inducible factor 1. Biochem Pharmacol 64: 993-998.
21. Kim M, Yan Y, Lee K, Sgagias M, Cowan KH (2004) Ectopic expression of von Hippel-Lindau tumor suppressor induces apoptosis in 786-O renal cell carcinoma cells and regresses tumor growth of 786-O cells in nude mouse. Biochem Biophys Res Commun 320: 945-950. (Pubitemid 38887235)
22. Guise TA (2000) Molecular mechanisms of osteolytic bone metastases. Cancer 88: 2892-2898.
23. Mundy GR (2002) Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2: 584-593.
24. Pan T, Zhu J, Hwu WJ, Jankovic J (2012) The role of alpha-synuclein in melanin synthesis in melanoma and dopaminergic neuronal cells. PLoS One 7: e45183.
25. Lee YC, Bilen MA, Yu G, Lin SC, Huang CF, et al. (2013) Inhibition of Cell Adhesion by an Anti-cadherin 11 Antibody Prevents Bone Metastasis. Mol Cancer Res.
26. Fukuhara S, Sako K, Noda K, Zhang J, Minami M, et al. (2010) Angiopoietin- 1/Tie2 receptor signaling in vascular quiescence and angiogenesis. Histol Histopathol 25: 387-396.
27. Gibney GT, Aziz SA, Camp RL, Conrad P, Schwartz BE, et al. (2013) c-Met is a prognostic marker and potential therapeutic target in clear cell renal cell carcinoma. Ann Oncol 24: 343-349.
28. Harshman LC, Choueiri TK (2013) Targeting the Hepatocyte Growth Factor/c-Met Signaling Pathway in Renal Cell Carcinoma. Cancer J 19: 316-323.
29. Guise TA, Yin JJ, Thomas RJ, Dallas M, Cui Y, et al. (2002) Parathyroid hormone-related protein (PTHrP)-(1-139) isoform is efficiently secreted in vitro and enhances breast cancer metastasis to bone in vivo. Bone 30: 670-676. (Pubitemid 34475098)
30. Kakonen SM, Mundy GR (2003) Mechanisms of osteolytic bone metastases in breast carcinoma. Cancer 97: 834-839.
31. Sottnik JL, Keller ET (2013) Understanding and targeting osteoclastic activity in prostate cancer bone metastases. Curr Mol Med 13: 626-639.
32. Chang SK, Noss EH, Chen M, Gu Z, Townsend K, et al. (2011) Cadherin-11 regulates fibroblast inflammation. Proc Natl Acad Sci U S A 108: 8402-8407.
33. Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428.
34. Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
35. Zeisberg M, Neilson EG (2009) Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 119: 1429-1437.
36. Hazan RB, Qiao R, Keren R, Badano I, Suyama K (2004) Cadherin switch in tumor progression. Ann N Y Acad Sci 1014: 155-163. (Pubitemid 38594801)
37. Wheelock MJ, Shintani Y, Maeda M, Fukumoto Y, Johnson KR (2008) Cadherin switching. J Cell Sci 121: 727-735. (Pubitemid 351578108)
38. Haviv YS, van Houdt WJ, Lu B, Curiel DT, Zhu ZB (2004) Transcriptional targeting in renal cancer cell lines via the human CXCR4 promoter. Mol Cancer Ther 3: 687-691. (Pubitemid 39193749)
39. Murakami T, Maki W, Cardones AR, Fang H, Tun Kyi A, et al. (2002) Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells. Cancer Res 62: 7328-7334. (Pubitemid 36025256)
40. D'Alterio C, Consales C, Polimeno M, Franco R, Cindolo L, et al. (2010) Concomitant CXCR4 and CXCR7 expression predicts poor prognosis in renal cancer. Curr Cancer Drug Targets 10: 772-781.
41. Wehler TC, Graf C, Biesterfeld S, Brenner W, Schadt J, et al. (2008) Strong expression of chemokine receptor CXCR4 by renal cell carcinoma correlates with advanced disease. J Oncol 2008: 626340.
42. Pan J, Mestas J, Burdick MD, Phillips RJ, Thomas GV, et al. (2006) Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol Cancer 5: 56.
43. Strewler GJ, Williams RD, Nissenson RA (1983) Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors. J Clin Invest 71: 769-774. (Pubitemid 13160826)
44. Zimmer M, Doucette D, Siddiqui N, Iliopoulos O (2004) Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors. Mol Cancer Res 2: 89-95. (Pubitemid 38250425)
45. Weber K, Doucet M, Kominsky S (2007) Renal cell carcinoma bone metastasis-elucidating the molecular targets. Cancer Metastasis Rev 26: 691-704. (Pubitemid 350115120)
46. Strube A, Stepina E, Mumberg D, Scholz A, Hauff P, et al. (2010) Characterization of a new renal cell carcinoma bone metastasis mouse model. Clin Exp Metastasis 27: 319-330.
47. Mikami S, Katsube K, Oya M, Ishida M, Kosaka T, et al. (2009) Increased RANKL expression is related to tumour migration and metastasis of renal cell carcinomas. J Pathol 218: 530-539.
48. Avnet S, Cenni E, Granchi D, Perut F, Amato I, et al. (2004) Isolation and characterization of a new cell line from a renal carcinoma bone metastasis. Anticancer Res 24: 1705-1711. (Pubitemid 38954698)