Effect of Linaclotide on Severe Abdominal Symptoms in Patients With Irritable Bowel Syndrome With Constipation

Clinical Gastroenterology and Hepatology

Volumn 12, Issue 4, 2014, Pages 616-623

  Rao, Satish S C ^a   Quigley, Eamonn M M ^b   Shiff, Steven J ^c   Lavins, Bernard J ^d   Kurtz, Caroline B ^d   MacDougall, James E ^d   Currie, Mark G ^d   Johnston, Jeffrey M ^d  

^a AUGUSTA UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c FOREST RESEARCH INSTITUTE   (United States)

^d Ironwood Pharmaceuticals   (United States)

Author keywords

Abdominal pain; Bloating; Guanylate cyclase C; IBS C

Indexed keywords

LINACLOTIDE; PLACEBO;

ABDOMINAL CRAMP; ABDOMINAL DISCOMFORT; ABDOMINAL DISEASE; ABDOMINAL PAIN; ADULT; AGED; ARTICLE; BLOATING; CONSTIPATION; CONTROLLED STUDY; DIARRHEA; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG SAFETY; FEMALE; FLATULENCE; HUMAN; INTENTION TO TREAT ANALYSIS; IRRITABLE BOWEL SYNDROME WITH CONSTIPATION; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTICENTER STUDY; PHASE 3 CLINICAL TRIAL; POST HOC ANALYSIS; PREVALENCE; QUALITY OF LIFE; QUALITY OF LIFE INDEX; RANDOMIZED CONTROLLED TRIAL; SYMPTOM; TREATMENT DURATION; VERY ELDERLY; YOUNG ADULT;

ABDOMINAL PAIN; BLOATING; GUANYLATE CYCLASE-C; IBS-C;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CONSTIPATION; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; PEPTIDES; PLACEBOS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84896082720     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2013.09.022     Document Type: Article

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