Clinical validation of a PCR assay for the detection of EGFR mutations in non-small-cell lung cancer: Retrospective testing of specimens from the EURTAC trial

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Benlloch, Susana ^a   Botero, Maria Luisa ^a   Beltran Alamillo, Jordi ^a   Mayo, Clara ^a   Gimenez Capitán, Ana ^a   De Aguirre, Itziar ^b   Queralt, Cristina ^b   Ramirez, Jose Luis ^b   Ramón Y Cajal, Santiago ^a,f   Klughammer, Barbara ^c   Schlegel, Mariette ^c   Bordogna, Walter ^c   Chen, David ^d   Zhang, Guili ^e   Kovach, Barbara ^e   Shieh, Felice ^e   Palma, John F ^e   Wu, Lin ^e   Lawrence, H Jeffrey ^e   Taron, Miquel ^a,b  

^a Pangaea Biotech SL   (Spain)

^b HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

^d GENENTECH INC   (United States)

^e ROCHE MOLECULAR SYSTEMS   (United States)

^f HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; EGFR PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER SCREENING; CONTROLLED STUDY; EGFR GENE; FEMALE; GENE MUTATION; HUMAN; LABORATORY TEST; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OUTCOME ASSESSMENT; PYROSEQUENCING; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; CARCINOMA, NON-SMALL-CELL LUNG; DNA SEQUENCE; GENETICS; LUNG NEOPLASMS; MUTATION; POLYMERASE CHAIN REACTION; PROCEDURES; PROSPECTIVE STUDY;

CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA;

EID: 84896075412     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089518     Document Type: Article

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