Combined management of retroperitoneal sarcoma with dose intensification radiotherapy and resection: Long-term results of a prospective trial

Radiotherapy and Oncology

Volumn 110, Issue 1, 2014, Pages 165-171

  Smith, Myles J F ^a   Ridgway, Paul F ^b   Catton, Charles N ^a,c   Cannell, Amanda J ^a   O'Sullivan, Brian ^a,c   Mikula, Lynn A ^d   Jones, Julia J ^e   Swallow, Carol J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ADELAIDE AND MEATH HOSPITAL   (Ireland)

^c UNIVERSITY OF TORONTO   (Canada)

^d Peterborough Clinic   (Canada)

^e LAKERIDGE HEALTH CORPORATION   (Canada)

Author keywords

Brachytherapy; Clinical trial; Local neoplasm recurrence; Operative surgical procedures; Phase II; Radioisotope; Radiotherapy; Sarcoma; Soft tissue; Targeted; Toxic potential

Indexed keywords

ADULT; AGED; ARTICLE; BRACHYTHERAPY; CANCER CONTROL; CANCER GRADING; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DIARRHEA; DUODENITIS; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; LONG TERM SURVIVAL; MAJOR CLINICAL STUDY; MALE; MALIGNANT FIBROUS HISTIOCYTOMA; MIDDLE AGED; MORBIDITY; MULTIMODALITY CANCER THERAPY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; POSTOPERATIVE CARE; PREOPERATIVE RADIOTHERAPY; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION DOSE INTENSIFICATION; RADIATION INJURY; RADIOLOGICAL PROCEDURES; RECURRENCE FREE SURVIVAL; RETROPERITONEAL SARCOMA; SMALL INTESTINE OBSTRUCTION; SURGICAL MORTALITY; TREATMENT PLANNING; ADJUVANT THERAPY; CLINICAL TRIAL; DISEASE FREE SURVIVAL; KAPLAN MEIER METHOD; MULTICENTER STUDY; PATHOLOGY; POSTOPERATIVE PERIOD; PROCEDURES; PROSPECTIVE STUDY; RETROPERITONEAL NEOPLASMS; RETROPERITONEUM; RETROSPECTIVE STUDY; SARCOMA; TUMOR RECURRENCE;

ADULT; AGED; BRACHYTHERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POSTOPERATIVE PERIOD; PROSPECTIVE STUDIES; RADIOTHERAPY, ADJUVANT; RETROPERITONEAL NEOPLASMS; RETROPERITONEAL SPACE; RETROSPECTIVE STUDIES; SARCOMA;

EID: 84896069458     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.10.041     Document Type: Article

References (41)

1. C.J. Swallow, and C.N. Catton Local management of adult soft tissue sarcomas Semin Oncol 34 2007 256 269 (Pubitemid 46874554)
2. S.J. Neuhaus, P. Barry, M.A. Clark, A.J. Hayes, C. Fisher, and J.M. Thomas Surgical management of primary and recurrent retroperitoneal liposarcoma Br J Surg 92 2005 246 252 (Pubitemid 40269344)
3. A. Stojadinovic, A. Yeh, and M.F. Brennan Completely resected recurrent soft tissue sarcoma: primary anatomic site governs outcomes J Am Coll Surg 194 2002 436 447 (Pubitemid 34274840)
4. C.N. Catton, B. O'Sullivan, C. Kotwall, B. Cummings, Y. Hao, and V. Fornasier Outcome and prognosis in retroperitoneal soft tissue sarcoma Int J Radiat Oncol Biol Phys 29 1994 1005 1010 (Pubitemid 24278967)
5. M.J. Heslin, J.J. Lewis, and E. Nadler et al. Prognostic factors associated with long-term survival for retroperitoneal sarcoma: implications for management J Clin Oncol 15 1997 2832 2839 (Pubitemid 27330010)
6. S. Singer, J.M. Corson, G.D. Demetri, E.A. Healey, K. Marcus, and T.J. Eberlein Prognostic factors predictive of survival for truncal and retroperitoneal soft-tissue sarcoma Ann Surg 221 1995 185 195
7. H. Nathan, C.P. Raut, and K. Thornton et al. Predictors of survival after resection of retroperitoneal sarcoma: a population-based analysis and critical appraisal of the AJCC staging system Ann Surg 250 2009 970 976
8. S. Bonvalot, R. Miceli, and M. Berselli et al. Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control Ann Surg Oncol 17 2010 1507 1514
9. A. Gronchi, R. Miceli, and C. Colombo et al. Frontline extended surgery is associated with improved survival in retroperitoneal low- to intermediate-grade soft tissue sarcomas Ann Oncol 23 2011 1067 1073
10. P.W. Pisters, L.B. Harrison, D.H. Leung, J.M. Woodruff, E.S. Casper, and M.F. Brennan Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma J Clin Oncol 14 1996 859 868 (Pubitemid 26085531)
11. J.C. Yang, A.E. Chang, and A.R. Baker et al. Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity J Clin Oncol 16 1998 197 203 (Pubitemid 28041599)
12. C.W. Tzeng, J.B. Fiveash, and R.A. Popple et al. Preoperative radiation therapy with selective dose escalation to the margin at risk for retroperitoneal sarcoma Cancer 107 2006 371 379 (Pubitemid 44036567)
13. L. Van De Voorde, L. Delrue, M. van Eijkeren, and G. De Meerleer Radiotherapy and surgery-an indispensable duo in the treatment of retroperitoneal sarcoma Cancer 117 2011 4355 4364
14. A. Pollack, G.K. Zagars, M.S. Goswitz, R.A. Pollock, B.W. Feig, and P.W. Pisters Preoperative vs. postoperative radiotherapy in the treatment of soft tissue sarcomas: a matter of presentation Int J Radiat Oncol Biol Phys 42 1998 563 572 (Pubitemid 28501106)
15. J.J. Jones, C.N. Catton, and B. O'Sullivan et al. Initial results of a trial of preoperative external-beam radiation therapy and postoperative brachytherapy for retroperitoneal sarcoma Ann Surg Oncol 9 2002 346 354 (Pubitemid 34496722)
16. S. Nag, D. Shasha, N. Janjan, I. Petersen, and M. Zaider The American Brachytherapy Society recommendations for brachytherapy of soft tissue sarcomas Int J Radiat Oncol Biol Phys 49 2001 1033 1043 (Pubitemid 32184610)
17. K.M. Alektiar, M.F. Brennan, and S. Singer Local control comparison of adjuvant brachytherapy to intensity-modulated radiotherapy in primary high-grade sarcoma of the extremity Cancer 117 2011 3229 3234
18. W. Dziewirski, P. Rutkowski, and Z.I. Nowecki et al. Surgery combined with intraoperative brachytherapy in the treatment of retroperitoneal sarcomas Ann Surg Oncol 13 2006 245 252 (Pubitemid 43157420)
19. S. Bonvalot, C.P. Raut, and R.E. Pollock et al. Technical considerations in surgery for retroperitoneal sarcomas: position paper from E-surge, a master class in sarcoma surgery, and EORTC-STBSG Ann Surg Oncol 19 2012 2981 2991
20. S. Bonvalot, M. Rivoire, and M. Castaing et al. Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control J Clin Oncol 27 2009 31 37
21. A. Gronchi, S. Bonvalot, A. Le Cesne, and P.G. Casali Resection of uninvolved adjacent organs can be part of surgery for retroperitoneal soft tissue sarcoma J Clin Oncol 27 2011 2106 2107 [author reply 2107-2108]
22. A. Gronchi, and R. Pollock Surgery in retroperitoneal soft tissue sarcoma: a call for a consensus between Europe and North America Ann Surg Oncol 18 2011 2107 2110
23. D.C. Strauss, A.J. Hayes, K. Thway, E.C. Moskovic, C. Fisher, and J.M. Thomas Surgical management of primary retroperitoneal sarcoma Br J Surg 97 2010 698 706
24. P.W. Pisters Resection of some - but not all - clinically uninvolved adjacent viscera as part of surgery for retroperitoneal soft tissue sarcomas J Clin Oncol 27 2009 6 8
25. W.F. Sindelar, T.J. Kinsella, and P.W. Chen et al. Intraoperative radiotherapy in retroperitoneal sarcomas. Final results of a prospective, randomized, clinical trial Arch Surg 128 1993 402 410 (Pubitemid 23115380)
26. R.D. Issels, L.H. Lindner, and J. Verweij et al. Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study Lancet Oncol 11 2010 561 570
27. T.M. Pawlik, P.W. Pisters, and L. Mikula et al. Long-term results of two prospective trials of preoperative external beam radiotherapy for localized intermediate- or high-grade retroperitoneal soft tissue sarcoma Ann Surg Oncol 13 2006 508 517
28. C. Llacer-Moscardo, F. Quenet, D. Azria, and P. Fenoglietto Feasibility study of volumetric modulated arc therapy for the treatment of retroperitoneal sarcomas Radiat Oncol 5 2010 83
29. J.M. Robertson, V.K. Sondak, S.A. Weiss, J.J. Sussman, A.E. Chang, and T.S. Lawrence Preoperative radiation therapy and iododeoxyuridine for large retroperitoneal sarcomas Int J Radiat Oncol Biol Phys 31 1995 87 92
30. A. Paumier, C. Le Pechoux, and A. Beaudre et al. IMRT or conformal radiotherapy for adjuvant treatment of retroperitoneal sarcoma? Radiother Oncol 99 2011 73 78
31. A. Gronchi, S. Lo Vullo, and M. Fiore et al. Aggressive surgical policies in a retrospectively reviewed single-institution case series of retroperitoneal soft tissue sarcoma patients J Clin Oncol 27 2008 24 30
32. R.J. Canter, L.X. Qin, C.R. Ferrone, R.G. Maki, S. Singer, and M.F. Brennan Why do patients with low-grade soft tissue sarcoma die? Ann Surg Oncol 15 2008 3550 3560
33. A.M. Koenig, M. Reeh, and C.M. Burdelski et al. Long-term results of primary and secondary resections in patients with retroperitoneal soft tissue sarcoma Langenbecks Arch Surg 397 2012 1251 1259
34. T.F. Delaney Radiation therapy: neoadjuvant, adjuvant, or not at all Surg Oncol Clin N Am 21 2012 215 241
35. N.N. Paryani, R.A. Zlotecki, and E.L. Swanson et al. Multimodality local therapy for retroperitoneal sarcoma Int J Radiat Oncol Biol Phys 82 2011 1128 1134
36. J.J. Lewis, D. Leung, J.M. Woodruff, and M.F. Brennan Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution Ann Surg 228 1998 355 365 (Pubitemid 30191698)
37. S. Singer, C.R. Antonescu, E. Riedel, and M.F. Brennan Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma Ann Surg 238 2003 358 370 [discussion 370-351]
38. E. Stoeckle, J.M. Coindre, and S. Bonvalot et al. Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group Cancer 92 2001 359 368 (Pubitemid 32664443)
39. K.M. Dalal, M.W. Kattan, C.R. Antonescu, M.F. Brennan, and S. Singer Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk Ann Surg 244 2006 381 391
40. R.A. Zlotecki, T.S. Katz, C.G. Morris, D.S. Lind, and S.N. Hochwald Adjuvant radiation therapy for resectable retroperitoneal soft tissue sarcoma: the University of Florida experience Am J Clin Oncol 28 2005 310 316 (Pubitemid 40800485)
41. K.M. Alektiar, K. Hu, L. Anderson, M.F. Brennan, and L.B. Harrison High-dose-rate intraoperative radiation therapy (HDR-IORT) for retroperitoneal sarcomas Int J Radiat Oncol Biol Phys 47 2000 157 163 (Pubitemid 30179689)