Montmorillonite-chitosan-silver sulfadiazine nanocomposites for topical treatment of chronic skin lesions: In vitro biocompatibility, antibacterial efficacy and gap closure cell motility properties

Carbohydrate Polymers

Volumn 102, Issue 1, 2014, Pages 970-977

  Sandri, Giuseppina ^a   Bonferoni, Maria Cristina ^a   Ferrari, Franca ^a   Rossi, Silvia ^a   Aguzzi, Carola ^b   Mori, Michela ^a   Grisoli, Pietro ^a   Cerezo, Pilar ^b   Tenci, Marika ^a   Viseras, Cesar ^b   Caramella, Carla ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

Antimicrobial properties; Chronic skin lesions; In vitro wound closure; Montmorillonite chitosan nanocomposites; Silver sulfadiazine

Indexed keywords

ANTI-MICROBIAL PROPERTIES; ANTIBACTERIAL EFFICACY; NORMAL HUMAN DERMAL FIBROBLASTS; PSEUDOMONAS AERUGINOSA; SILVER SULFADIAZINES; SKIN LESION; STREPTOCOCCUS PYOGENES; WOUND CLOSURE;

AIRCRAFT PROPULSION; BACTERIA; BIOCOMPATIBILITY; CELL CULTURE; CHITOSAN; CLAY MINERALS; CYTOTOXICITY; DERMATOLOGY; ENZYME INHIBITION; ESCHERICHIA COLI; FIBROBLASTS; NANOCOMPOSITES; SILVER; VIRUSES;

LOADING;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; FUNGI; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES;

ANTIINFECTIVE AGENT; BENTONITE; BIOMATERIAL; CHITOSAN; NANOCOMPOSITE; SULFADIAZINE SILVER;

ANTIMICROBIAL PROPERTIES; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; CHRONIC SKIN LESIONS; DRUG EFFECT; HUMAN; IN VITRO STUDY; IN VITRO WOUND CLOSURE; MONTMORILLONITE CHITOSAN NANOCOMPOSITES; TOPICAL DRUG ADMINISTRATION;

ANTIMICROBIAL PROPERTIES; CHRONIC SKIN LESIONS; IN VITRO WOUND CLOSURE; MONTMORILLONITE CHITOSAN NANOCOMPOSITES; SILVER SULFADIAZINE;

ADMINISTRATION, TOPICAL; ANTI-BACTERIAL AGENTS; BENTONITE; BIOCOMPATIBLE MATERIALS; CELL PROLIFERATION; CELLS, CULTURED; CHITOSAN; HUMANS; NANOCOMPOSITES; SILVER SULFADIAZINE;

EID: 84896061110     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2013.10.029     Document Type: Article

References (32)

1. C. Aguzzi, P. Cerezo, C. Viseras, and C. Caramella Use of clays as drug delivery systems: Possibilities and limitations Applied Clay Science 36 2007 22 36 (Pubitemid 46404593)
2. C. Aguzzi, G. Sandri, C. Viseras, M.C. Bonferoni, P. Cerezo, and S. Rossi et al. Solid state characterization of silver sulfadiazine loaded on montmorillonite/chitosan nanocomposite for wound healing Colloids and Surfaces B: Biointerfaces 113 2014 152 157 10.1016/j.colsurfb.2013.08.043
3. Antelman, P., Goldsmith, D., & Lampert, S. (2011). Topical antibiotic formulations. Patent No. WO 2011/097546 A2.
4. B.S. Atiyeh, M. Costagliola, S.N. Hayek, and S.A. Dibo Effect of silver on burn wound infection control and healing: Review of the literature Burns 33 2007 139 148 (Pubitemid 46188672)
5. S. Bergin, and P. Wraight Silver based wound dressings and topical agents for treating diabetic foot ulcers Cochrane Database of Systematic Reviews 2006 Art. No.: CD005082
6. C.-W. Chiu, and J.-J. Lin Self-assembly behavior of polymer-assisted clays Progress in Polymer Science 37 2012 406 444
7. D. Depan, A.P. Kumar, and R.P. Singh Cell proliferation and controlled drug release studies of nanohybrids based on chitosan-g-lactic acid and montmorillonite Acta Biomaterialia 5 2009 93 100
8. A. Francesko, and T. Tzanov Chitin, chitosan and derivatives for wound healing and tissue engineering Advances in Biochemical Engineering/Biotechnology 125 2011 1 27
9. E. Günister, D. Pestreli, C.H. Ünlü, and N. Güngör Synthesis and characterization of chitosan-MMT biocomposite systems Carbohydrate Polymers 67 2007 358 365 (Pubitemid 44881117)
10. A.A. Haroun, A. Gamal-Eldeen, and D.R.K. Harding Preparation, characterization and in vitro biological study of biomimetic three-dimensional gelatin-montmorillonite/cellulose scaffold for tissue engineering Journal of Materials Science 20 2009 2527 2540
11. S.-H. Hsu, M.-C. Wang, and J.-J. Lin Biocompatibility and antimicrobial evaluation of montmorillonite/chitosan nanocomposites Applied Clay Science 56 2012 53 62
12. G.V. Joshi, B.D. Kevadiya, H.M. Mody, and H.C. Bajaj Confinement and controlled release of quinine on chitosan-montmorillonite bionanocomposites Journal of Polymer Science Part A: Polymer Chemistry 50 2012 423 430
13. K.S. Katti, D.R. Katti, and R. Dash Synthesis and characterization of a novel chitosan/montmorillonite/hydroxyapatite nanocomposite for bone tissue engineering Biomedical Materials 3 2008 034122
14. W. Khunawattanakul, S. Puttipipatkhachorn, T. Rades, and T. Pongjanyakul Chitosan-magnesium aluminum silicate composite dispersions: Characterization of rheology, flocculate size and zeta potential International Journal of Pharmaceutics 351 2008 227 235 (Pubitemid 351193099)
15. M.M. Leane, R. Nankervis, A. Smith, and L. Illum Use of the ninhydrin assay to measure the release of chitosan from oral solid dosage forms International Journal of Pharmaceutics 271 2004 241 249 (Pubitemid 38210102)
16. P. Lertsutthiwong, K. Noomun, S. Khunthon, and S. Limpanart Influence of chitosan characteristics on the properties of biopolymeric chitosan- montmorillonite Natural Science: Materials International 22 2012 502 508
17. B.A. Lipsky, and C. Hoey Topical antimicrobial therapy for treating chronic wounds Clinical Infectious Diseases 49 2009 1541 1549
18. M.J. Muller, M.A. Hollyoak, Z. Moaveni, T.L.H. Brown, D.N. Herndon, and J.P. Heggers Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin Burns 29 2003 834 836 (Pubitemid 37433921)
19. NCCLS Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically Approved Standard M7-A6, 6th ed. Wayne, PA 2003
20. P.V. Popryadukhin, I.P. Dobrovolskaya, V.E. Yudin, I.E. Mvankova, A.B. Smolyaninov, and N.V. Smirnova Composite materials based on chitosan and montmorillonite prospects for use as matrix for culturing of stem and regenerative cells Cell and Tissue Biology 6 2012 82 88
21. E. Ranzato, S. Martinotti, A. Volante, L. Mazzucco, and B. Burlando Platelet lysate modulates MMP-2 and MMP-9 expression, matrix deposition and cell-to-matrix adhesion in keratinocytes and fibroblasts Experimental Dermatology 20 2010 308 313
22. I. Salcedo, C. Aguzzi, G. Sandri, M.C. Bonferoni, M. Mori, and P. Cerezo et al. In vitro biocompatibility and mucoadhesion of montmorillonite chitosan nanocomposite: A new drug delivery Applied Clay Science 55 2012 131 137
23. G. Sandri, M.C. Bonferoni, F. D'Autilia, S. Rossi, F. Ferrari, and P. Grisoli et al. Wound dressings based on silver sulfadiazine SLN for tissue repairing European Journal of Pharmaceutics and Biopharmaceutics 84 2013 84 90
24. G. Sandri, M.C. Bonferoni, S. Rossi, F. Ferrari, M. Mori, and C. Del Fante et al. Platelet lysate formulations based on mucoadhesive polymers for the treatment of corneal lesions Journal of Pharmacy and Pharmacology 63 2011 189 219
25. M.N. Storm-Versloot, C.G. Vos, D.T. Ubbink, and H. Vermeulen Topical silver for preventing wound infection Cochrane Database of Systemic Reviews 2010 Art No.: CD006478
26. T. Takahashi, Y. Yamada, K. Kataoka, and Y. Nagasaki Preparation of a novel PEG-clay hybrid as a DDS material: Dispersion stability and sustained release profiles Journal of Controlled Release 107 2005 408 416 (Pubitemid 41398068)
27. C.A. Vaiana, M.K. Leonard, L.F. Drummy, K.M. Singh, A. Bubulya, and R.A. Vaia et al. Epidermal growth factor: Layered silicate nanocomposites for tissue regeneration Biomacromolecules 12 2011 3139 3146
28. C. Viseras, C. Aguzzi, P. Cerezo, and M.C. Bedmar Biopolymer-clay nanocomposites for controlled drug delivery Materials Science and Technology 24 2008 1020 1026
29. C. Viseras, P. Cerezo, R. Sanchez, I. Salcedo, and C. Aguzzi Current challenges in clay minerals for drug delivery Applied Clay Sciences 48 2010 291 295
30. X. Wang, Y. Du, and J. Luo Biopolymer/montmorillonite nanocomposite: Preparation, drug-controlled release property and cytotoxicity Nanotechnology 19 2008 065707
31. J. Wasiak, H. Cleland, and F. Campbell Dressings for superficial and partial thickness burns Cochrane Database of Systematic Reviews 2008 Art. No.: CD002106
32. T.M. Wu, and C.Y. Wu Biodegradable poly (lactic acid)/chitosan-modified montmorillonite nanocomposites: Preparation and characterization Polymer Degradation and Stability 9 2006 2198 2204