Yersinia pestis Ail recruitment of C4b-binding protein leads to factor I-mediated inactivation of covalently and noncovalently bound C4b

European Journal of Immunology

Volumn 44, Issue 3, 2014, Pages 742-751

  Ho, Derek K ^a   Skurnik, Mikael ^a,b   Blom, Anna M ^c   Meri, Seppo ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Ail; C4b binding protein; Complement; Yersinia

Indexed keywords

COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C4B; COMPLEMENT COMPONENT C4B BINDING PROTEIN; FIBRINOGEN; MONOCLONAL ANTIBODY; MUTANT PROTEIN; OUTER MEMBRANE PROTEIN; PROTEIN AIL; SERINE PROTEINASE; UNCLASSIFIED DRUG; AIL PROTEIN, YERSINIA PESTIS; BLOCKING ANTIBODY; C4BPA PROTEIN, HUMAN; PROTEIN BINDING; RECOMBINANT PROTEIN; VIRULENCE FACTOR;

ALPHA CHAIN; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL OUTER MEMBRANE; BINDING AFFINITY; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; CONTROLLED STUDY; COVALENT BOND; DISSOCIATION CONSTANT; HUMAN; IMMUNOBLOTTING; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DOMAIN; YERSINIA PESTIS; DRUG EFFECTS; GENETICS; IMMUNE EVASION; IMMUNOLOGY; METABOLISM; MUTATION; PATHOGENICITY; PLAGUE; PROTEIN ENGINEERING; VIRULENCE;

BINDING SITES; COMPLEMENT ACTIVATION; COMPLEMENT C4B; COMPLEMENT C4B-BINDING PROTEIN; COMPLEMENT PATHWAY, CLASSICAL; FIBRINOGEN; HUMANS; KINETICS; PLAGUE; PROTEIN BINDING; YERSINIA PESTIS; ANTIBODIES, BLOCKING; BACTERIAL OUTER MEMBRANE PROTEINS; IMMUNE EVASION; MUTATION; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; VIRULENCE; VIRULENCE FACTORS;

EID: 84896050071     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343552     Document Type: Article

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