Simultaneous Determination of Six Quaternary Ammonium Alkaloids in Coptidis Rhizoma by UPLC

Chinese Herbal Medicines

Volumn 4, Issue 2, 2012, Pages 164-169

  QIU, Ling ling ^a,b   CHEN, Long hu ^a,c   YAN, Dan ^a   ZHANG, Ping ^a   TAN, Man rong ^a,b   DU, Xiao xi ^d   XIAO, Xiao he ^a  

^a 302 MILITARY HOSPITAL   (China)

^b JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d Center for Drug Reevaluation State Food and Drug Administration   (China)

Author keywords

Coptidis Rhizoma; method validation; quaternary ammonium alkaloids; simultaneous determination; ultra performance liquid chromatography

Indexed keywords

EID: 84896045874     PISSN: 16746384     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1674-6384.2012.02.011     Document Type: Article

References (21)

1. Bing, FH, Liu, J, Li, Z, Zhang, GB, Liao, YF, Li, J, Dong, CY, Anti-influenza-virus activity of total alkaloids from Commelina communis L. Arch Virol 154:11 (2009), 1837–1840.
2. Chen, JH, Wang, FM, Liu, J, Lee, FSC, Wang, XR, Yang, HH, Analysis of alkaloids in Coptis chinensis Franch. by accelerated solvent extraction combined with ultra performance liquid chromatographic analysis with photodiode array and tandem mass spectrometry detections. Anal Chim Acta 613:2 (2008), 184–195.
3. Chen, JH, Zhao, HQ, Wang, XR, Lee, FSC, Yang, HH, Zheng, L, Analysis of major alkaloids in Rhizoma Coptidis by capillary electrophoresis electrospray-time of flight mass spectrometry with different background electrolytes. Electrophoresis 29:10 (2008), 2135–2147.
4. Chu, CY, Sheu, SJ, Liquid chromatographic separation of the alkaloids in coptis-evodia herb couple. J Chromatogr A 756:1/2 (1996), 137–144.
5. Deng, XK, Yin, W, Li, WD, Yin, FZ, Lu, XY, Zhang, XC, Hua, ZC, Cai, BC, The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism. J Ethnopharmacol 106:2 (2006), 179–186.
6. Ding, B, Zhou, TT, Fan, GR, Hong, ZY, Wu, YT, Qualitative and quantitative determination of ten alkaloids in traditional Chinese medicine Corydalis yanhusuo W. T. Wang by LC-MS/MS and LC-DAD. J Pharm Biomed 45:2 (2007), 219–226.
7. Gao, X, Yang, XW, Marriott, PJ, Simultaneous analysis of seven alkaloids in Coptis-Evodia herb couple and Zuojin pill by UPLC with accelerated solvent extraction. J Sep Sci 33:17/18 (2010), 2714–2722.
8. Geng, Z, Zheng, H, Zhang, Y, Luo, W, Qu, X, Simultaneous determination of six alkaloids in Coptis chinensis of different regions by RP-HPLC. Chin J Chin Mater Med 35:19 (2010), 2576–2580.
9. Gu, Y, Zhang, YF, Shi, XZ, Li, XY, Hong, J, Chen, J, Gu, WQ, Lu, X, Xu, GW, Ning, G, Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics. Talanta 81:3 (2010), 766–772.
10. Kulkarni, SK, Dhir, A, Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chlorid. Eur J Pharmacol 569:1/2 (2007), 77–83.
11. Kulkarni, SK, Dhir, A, Berberine: A plant alkaloid with therapeutic potential for central nervous system disorders. Phytother Res 24:3 (2010), 317–324.
12. McCalley, DV, Analysis of the Cinchona alkaloids by high-performance liquid chromatography and other separation techniques. J Chromatogr A 967:1 (2002), 1–19.
13. Pharmacopeia Committee of P. R. China, Pharmacopoeia of People's Republic of China, 2010, China Medical Science and Technology Press, Beijing.
14. Ren, LL, Xue, XY, Zhang, FF, Xu, Q, Liang, XM, High performance liquid chromatography-mass spectrometry analysis of protoberberine alkaloids in medicine herbs. J Sep Sci 30:6 (2007), 833–842.
15. nd, 1997, John Wiley & Sons, Inc, New York.
16. Stöckigt, J, Sheludko, Y, Unger, M, Gerasimenko, I, Warzecha, H, Stöckigt, D, High-performance liquid chromatographic, capillary electrophoretic and capillary electrophoretic-electrospray ionisation mass spectrometric analysis of selected alkaloid groups. J Chromatogr A 967:1 (2002), 85–113.
17. Wang, XN, Xu, LN, Peng, JY, Liu, KX, Zhang, LH, Zhang, YK, In vivo inhibition of S180 tumors by the synergistic effect of the Chinese medicinal herbs Coptis chinensis and Evodia rutaecarpa. Planta Med 75:11 (2009), 1215–1220.
18. Wang, JB, Li, HF, Jin, C, Qu, Y, Xiao, XH, Development and validation of a UPLC method for quality control of rhubarb-based medicine: Fast simultaneous determination of five anthraquinone derivatives. J Pharm Biomed Anal 47:4/5 (2008), 765–770.
19. Ye, MZ, Fu, S, Pi, RB, He, F, Neuropharmacological and pharmacokinetic properties of berberine: A review of recent research. J Pharm Pharmacol 61:7 (2009), 831–837.
20. Zhang, SJ, Wang, MY, Wang, CH, Preparative separation and purification of alkaloids from Rhizoma coptidis by high-speed counter-current chromatography. Sep Purif Technol 76:3 (2011), 428–431.
21. nd, 2001, Science Press, Beijing.