Cryogenic transmission electron microscopy of recombinant tuberculosis vaccine antigen with anionic liposomes reveals formation of flattened liposomes

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 1367-1377

  Fox, Christopher B ^a   Mulligan, Sean K ^b   Sung, Joyce ^b   Dowling, Quinton M ^a   Fung, H W Millie ^a   Vedvick, Thomas S ^a   Coler, Rhea N ^a  

^a INFECTIOUS DISEASE RESEARCH INSTITUTE   (United States)

^b Nano Imaging Services   (United States)

Author keywords

3D tomographic reconstruction; Antigen adjuvant interactions; Cryo TEM; Vaccine adjuvant; Vaccine formulation morphology; Vaccine physical characterization

Indexed keywords

ANION; BCG VACCINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLGLYCEROL; HYBRID PROTEIN; ID 93; LIPOSOME; RECOMBINANT VACCINE; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; IMMUNOLOGICAL ADJUVANT; NANOPARTICLE;

ANALYTIC METHOD; ARTICLE; CRYOGENIC TRANSMISSION ELECTRON MICROSCOPY; DRUG DETERMINATION; DRUG FORMULATION; IMAGE RECONSTRUCTION; ISOELECTRIC POINT; LIGHT SCATTERING; MOLECULAR INTERACTION; PARTICLE SIZE; THREE DIMENSIONAL IMAGING; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CHEMISTRY; CRYOELECTRON MICROSCOPY; HUMAN; IMMUNOLOGY; NANOMEDICINE; ULTRASTRUCTURE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, BACTERIAL; CRYOELECTRON MICROSCOPY; HUMANS; IMAGING, THREE-DIMENSIONAL; LIPOSOMES; NANOMEDICINE; NANOPARTICLES; PARTICLE SIZE; TUBERCULOSIS VACCINES; VACCINES, SYNTHETIC;

EID: 84896035445     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S56582     Document Type: Article

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