B7-H6 protein expression has no prognostic significance in human gastric carcinoma

Pathology and Oncology Research

Volumn 20, Issue 1, 2014, Pages 203-207

  Chen, Xiao Juan ^a   Shen, Jin ^a   Zhang, Guang Bo ^a   Chen, Wei Chang ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Adjacent non tumor tissues; B7 H6; Gastric carcinoma; Immunohistochemistry

Indexed keywords

B7 H6 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROTEIN EXPRESSION; STOMACH CANCER; SURVIVAL; SURVIVAL TIME; TUMOR DIFFERENTIATION; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; B7 ANTIGENS; CARCINOMA; CELL DIFFERENTIATION; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROGNOSIS; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84896034781     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-013-9686-1     Document Type: Article

References (15)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer Clin 61:69-90. doi:10.3322/caac
2. Zang X, Allison JP (2007) The B7 family and cancer therapy. Costimulation and coinhibition. Clin Cancer Res 13:5271-5279 (Pubitemid 47510350)
3. Greaves P, Gribben JG (2013) The role of B7 family molecules in hematologic malignancy. Blood 121:734-744. doi:10.1182/blood-2012-10-385591
4. Lu B, Chen L, Liu L, Zhu Y, Wu C, Jiang J, Zhang X (2011) T-cell-mediated tumor immune surveillance and expression of B7 co-inhibitory molecules in cancers of the upper gastrointestinal tract. Immunol Res 50:269-275. doi:10.1007/s12026-011-8227-9
5. Capece D, Verzella D, Fischietti M, Zazzeroni F, Alesse E (2012) Targeting costimulatory molecules toimprove antitumor immunity. J Biomed Biotechnol 2012:926321. doi:10.1155/2012/926321
6. Seliger B, Quandt D (2012) The expression, function, and clinical relevance of B7 family members in cancer. Cancer Immunol Immunother 61:1327-1341. doi:10.1007/s00262-012-1293-6
7. Brandt CS, Baratin M, Yi EC, Kennedy J, Gao Z, Fox B, Haldeman B, Ostrander CD, Kaifu T, Chabannon C, Moretta A, West R, Xu W, Vivier E, Levin SD (2009) The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med 206:1495-1503. doi:10.1084/jem.20090681
8. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A (2009) AJCC cancer staging manual, 7th edn. Springer-verlag, New York
9. Wu C, Zhu Y, Jiang J, Zhao J, Zhang XG, Xu N (2006) Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance. Acta Histochem 108:19-24 (Pubitemid 44316588)
10. Liu SM, Meng Q, Zhang QX (2008) Expression and significance of B7-H1 and its receptor PD-1 in human gastric carcinoma. Zhonghua Zhong Liu Za Zhi 30:192-195
11. Sun J, Xu K, Wu C, Wang Y, Hu Y, Zhu Y, Chen Y, Shi Q, Yu G, Zhang X (2007) PD-L1 expression analysis in gastric carcinoma tissue and blocking of tumor-associated PD-L1 signaling by two functional monoclonal antibodies. Tissue Antigens 69:19-27 (Pubitemid 46025335)
12. Wu CP, Jiang JT, Tan M, Zhu YB, Ji M, Xu KF, Zhao JM, Zhang GB, Zhang XG (2006) Relationship between co-stimulatorymolecule B7-H3 expression and gastric carcinoma histology and prognosis. World J Gastroenterol 12:457-459 (Pubitemid 43329266)
13. Arigami T, Uenosono Y, Hirata M, Yanagita S, Ishigami S, Natsugoe S (2011) B7-H3 expression in gastric cancer: a novel molecular blood marker for detecting circulating tumor cells. Cancer Sci 102:1019-1024. doi:10.1111/j.1349-7006.2011.01877.x
14. Arigami T, Uenosono Y, Ishigami S, Hagihara T, Haraguchi N, Natsugoe S (2011) Clinical significance of the B7-H4 coregulatory moleculeas a novel prognostic marker in gastric cancer. World J Surg 35:2051-2057. doi:10.1007/s00268-011-1186-4
15. Jiang J, Zhu Y, Wu C, Shen Y, Wei W, Chen L, Zheng X, Sun J, Lu B, Zhang X (2010) Tumor expression of B7-H4 predicts poor survival of patients suffering from gastric cancer. Cancer Immunol Immunother 59:1707-1714