Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis

Developmental Biology

Volumn 388, Issue 2, 2014, Pages 159-169

  Williams, Dustin R ^a   Shifley, Emily T ^a,b   Lather, Jason D ^a,c   Cole, Susan E ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b Hospital Medical Center   (United States)

^c MERCY HEALTH PARTNERS   (United States)

Author keywords

Lfng; Notch pathway; Secondary body formation; Segmentation clock; Somitogenesis

Indexed keywords

ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CIRCADIAN RHYTHM; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; EMBRYO SEGMENTATION; GENE DOSAGE; LUNATIC FRINGE GENE; MESODERM; MOUSE; NONHUMAN; PRESOMITIC MESODERM; PRIORITY JOURNAL; SEGMENTATION CLOCK; SOMITE; SOMITOGENESIS; TAIL; ALLELE; GENOTYPE; IMMUNOHISTOCHEMISTRY; MOLECULAR CLOCK; MOUSE STRAIN; OSCILLATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

MUS;

GENOMIC DNA; LUNATIC FRINGE PROTEIN; NOTCH RECEPTOR; RNA; UNCLASSIFIED DRUG;

LFNG; NOTCH PATHWAY; SECONDARY BODY FORMATION; SEGMENTATION CLOCK; SOMITOGENESIS;

ANIMALS; BONE DEVELOPMENT; GENE DOSAGE; GLYCOSYLTRANSFERASES; MICE; MICE, TRANSGENIC; SOMITES;

EID: 84895930030     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.02.006     Document Type: Article

References (32)

1. Christ B., Schmidt C., Huang R., Wilting J., Brand-Saberi B. Segmentation of the vertebrate body. Anat. Embryol. 1998, 197:1-8.
2. Cole S.E., Levorse J.M., Tilghman S.M., Vogt T.F. Clock regulatory elements control cyclic expression of lunatic fringe during somitogenesis. Dev. Cell 2002, 3:75-84.
3. Cordes R., Schuster-Gossler K., Serth K., Gossler A. Specification of vertebral identity is coupled to notch signalling and the segmentation clock. Development 2004, 131:1221-1233.
4. Delaune E.A., Francois P., Shih N.P., Amacher S.L. Single-cell-resolution imaging of the impact of notch signaling and mitosis on segmentation clock dynamics. Dev. Cell 2012, 23:995-1005.
5. Evrard Y.A., Lun Y., Aulehla A., Gan L., Johnson R.L. Lunatic fringe is an essential mediator of somite segmentation and patterning. Nature 1998, 394:377-381.
6. Handrigan G.R. Concordia discors: duality in the origin of the vertebrate tail. J. Anat. 2003, 202:255-267.
7. Haraguchi S., Kitajima S., Takagi A., Takeda H., Inoue T., Saga Y. Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development. Mech. Dev. 2001, 108:59-69.
8. Harima Y., Takashima Y., Ueda Y., Ohtsuka T., Kageyama R. Accelerating the tempo of the segmentation clock by reducing the number of introns in the hes7 gene. Cell Rep. 2013, 3:1-7.
9. Holmdahl D.E. Experimentelle untersuchungen uber die lage der grenze zwischen primarer und sekundarere korperentwicklung beim huhn. Anat. Anz. 1925, 59:393-396.
10. Horikawa K., Ishimatsu K., Yoshimoto E., Kondo S., Takeda H. Noise-resistant and synchronized oscillation of the segmentation clock. Nature 2006, 441:719-723.
11. Jiang Y.J., Aerne B.L., Smithers L., Haddon C., Ish-Horowicz D., Lewis J. Notch signalling and the synchronization of the somite segmentation clock. Nature 2000, 408:475-479. (in process citation).
12. Johnston S.H., Rauskolb C., Wilson R., Prabhakaran B., Irvine K.D., Vogt T.F. A family of mammalian fringe genes implicated in boundary determination and the notch pathway. Development 1997, 124:2245-2254.
13. Kim D.G., Kang H.M., Jang S.K., Shin H.S. Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus. Mol. Cell. Biol. 1992, 12:3636-3643.
14. Kim W., Matsui T., Yamao M., Ishibashi M., Tamada K., Takumi T., Kohno K., Oba S., Ishii S., Sakumura Y., Bessho Y. The period of the somite segmentation clock is sensitive to notch activity. Mol. Biol. Cell 2011, 22:3541-3549.
15. Mansouri A., Yokota Y., Wehr R., Copeland N.G., Jenkins N.A., Gruss P. Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system. Dev. Dyn. 1997, 210:53-65.
16. Mara A., Schroeder J., Chalouni C., Holley S.A. Priming, initiation and synchronization of the segmentation clock by deltaD and deltaC. Nat. Cell Biol. 2007, 9:523-530.
17. McLeod M.J. Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratology 1980, 22:299-301.
18. Morales A.V., Yasuda Y., Ish-Horowicz D. Periodic lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling. Dev. Cell 2002, 3:63-74.
19. Oginuma M., Takahashi Y., Kitajima S., Kiso M., Kanno J., Kimura A., Saga Y. The oscillation of notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite. Development 2010, 137:1515-1522.
20. Ozbudak E.M., Lewis J. Notch signalling synchronizes the zebrafish segmentation clock but is not needed to create somite boundaries. PLoS Genet. 2008, 4:e15.
21. Pourquie O. Vertebrate segmentation: from cyclic gene networks to scoliosis. Cell 2011, 145:650-663.
22. Riedel-Kruse I.H., Muller C., Oates A.C. Synchrony dynamics during initiation, failure, and rescue of the segmentation clock. Science 2007, 317:1911-1915.
23. Saga Y., Hata N., Koseki H., Taketo M.M. Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 1997, 11:1827-1839.
24. Saga Y., Takeda H. The making of the somite: molecular events in vertebrate segmentation. Nat. Rev. Genet. 2001, 2:835-845.
25. Shifley E.T., Cole S.E. The vertebrate segmentation clock and its role in skeletal birth defects. Birth Defects Res. C: Embryo Today 2007, 81:121-133.
26. Shifley E.T., Vanhorn K.M., Perez-Balaguer A., Franklin J.D., Weinstein M., Cole S.E. Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton. Development 2008, 135:899-908.
27. Sparrow D.B., Chapman G., Dunwoodie S.L. The mouse notches up another success: understanding the causes of human vertebral malformation. Mamm. Genome 2011, 22:362-376.
28. Stauber M., Sachidanandan C., Morgenstern C., Ish-Horowicz D. Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis. PLoS One 2009, 4:e7996.
29. Tam P.P. The control of somitogenesis in mouse embryos. J. Embryol. Exp. Morphol. 1981, 65(Suppl.):103-128.
30. Tenin G., Wright D., Ferjentsik Z., Bone R., McGrew M.J., Maroto M. The chick somitogenesis oscillator is arrested before all paraxial mesoderm is segmented into somites. BMC Dev. Biol. 2010, 10. 10.1186/1471-213X-10-24.
31. Whiting J., Marshall H., Cook M., Krumlauf R., Rigby P.W., Stott D., Allemann R.K. Multiple spatially specific enhancers are required to reconstruct the pattern of hox-2.6 gene expression. Genes Dev. 1991, 5:2048-2059.
32. Wilson V., Beddington R.S. Cell fate and morphogenetic movement in the late mouse primitive streak. Mech. Dev. 1996, 55:79-89.