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Volumn 92, Issue 5, 2014, Pages 641-650

Influence of APOE genotype and the presence of Alzheimer's pathology on synaptic membrane lipids of human brains

Author keywords

Alzheimer's disease; Cholesterol; Ganglioside; Microdomain; Synaptic plasma membrane

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; CHOLESTEROL; GANGLIOSIDE; GANGLIOSIDE GD1; GANGLIOSIDE GM1; GANGLIOSIDE GT1; MEMBRANE LIPID; UNCLASSIFIED DRUG;

EID: 84895920241     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23341     Document Type: Article
Times cited : (22)

References (50)
  • 2
    • 48549100652 scopus 로고    scopus 로고
    • Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease-a review
    • Ariga T, McDonald MP, Yu RK. 2008. Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease-a review. J Lipid Res 49:1157-1175.
    • (2008) J Lipid Res , vol.49 , pp. 1157-1175
    • Ariga, T.1    McDonald, M.P.2    Yu, R.K.3
  • 5
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. 1991. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 6
    • 0025002019 scopus 로고
    • Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits
    • Bugiani O, Giaccone G, Verga L, Pollo B, Ghetti B, Frangione B, Tagliavini F. 1990. Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits. Neurosci Lett 119:56-59.
    • (1990) Neurosci Lett , vol.119 , pp. 56-59
    • Bugiani, O.1    Giaccone, G.2    Verga, L.3    Pollo, B.4    Ghetti, B.5    Frangione, B.6    Tagliavini, F.7
  • 7
    • 0033869715 scopus 로고    scopus 로고
    • Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations
    • Cataldo AM, Peterhoff CM, Troncoso JC, Gomez-Isla T, Hyman BT, Nixon RA. 2000. Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations. Am J Pathol 157:277-286.
    • (2000) Am J Pathol , vol.157 , pp. 277-286
    • Cataldo, A.M.1    Peterhoff, C.M.2    Troncoso, J.C.3    Gomez-Isla, T.4    Hyman, B.T.5    Nixon, R.A.6
  • 8
    • 77953273656 scopus 로고    scopus 로고
    • Cholesterol changes in Alzheimer's disease: methods of analysis and impact on the formation of enlarged endosomes
    • Cossec JC, Marquer C, Panchal M, Lazar AN, Duyckaerts C, Potier MC. 2010a. Cholesterol changes in Alzheimer's disease: methods of analysis and impact on the formation of enlarged endosomes. Biochim Biophys Acta 1801:839-845.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 839-845
    • Cossec, J.C.1    Marquer, C.2    Panchal, M.3    Lazar, A.N.4    Duyckaerts, C.5    Potier, M.C.6
  • 10
    • 0015209726 scopus 로고
    • Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization
    • Cotman CW, Matthews DA. 1971. Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization. Biochim Biophys Acta 249:380-394.
    • (1971) Biochim Biophys Acta , vol.249 , pp. 380-394
    • Cotman, C.W.1    Matthews, D.A.2
  • 12
    • 79955051063 scopus 로고    scopus 로고
    • Linking lipids to Alzheimer's disease: cholesterol and beyond
    • Di Paolo G, Kim TW. 2011. Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat Rev Neurosci 12:284-296.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 284-296
    • Di Paolo, G.1    Kim, T.W.2
  • 13
    • 84895919886 scopus 로고    scopus 로고
    • Mechanism of cholesterol-assisted oligomeric channel formation by a short Alzheimer β-amyloid peptide
    • in press
    • Di Scala C, Troadec JD, Lelièvre C, Garmy N, Fantini J, Chahinian H. 2013. Mechanism of cholesterol-assisted oligomeric channel formation by a short Alzheimer β-amyloid peptide. J Neurochem (in press).
    • (2013) J Neurochem
    • Di Scala, C.1    Troadec, J.D.2    Lelièvre, C.3    Garmy, N.4    Fantini, J.5    Chahinian, H.6
  • 15
    • 84884538771 scopus 로고    scopus 로고
    • Cholesterol accelerates the binding of Alzheimer's β-amyloid peptide to ganglioside GM1 through a universal hydrogen-bond-dependent sterol tuning of glycolipid conformation
    • Fantini J, Yahi N, Garmy N. 2013. Cholesterol accelerates the binding of Alzheimer's β-amyloid peptide to ganglioside GM1 through a universal hydrogen-bond-dependent sterol tuning of glycolipid conformation. Front Physiol 4:120.
    • (2013) Front Physiol , vol.4 , pp. 120
    • Fantini, J.1    Yahi, N.2    Garmy, N.3
  • 16
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M, Sloane Stanley GH. 1957. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226:497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 17
    • 0018866085 scopus 로고
    • Aminophospholipid asymmetry in murine synaptosomal plasma membrane
    • Fontaine RN, Harris RA, Schroeder F. 1980. Aminophospholipid asymmetry in murine synaptosomal plasma membrane. J Neurochem 34:269-277.
    • (1980) J Neurochem , vol.34 , pp. 269-277
    • Fontaine, R.N.1    Harris, R.A.2    Schroeder, F.3
  • 18
    • 33646557678 scopus 로고    scopus 로고
    • The role of lipid-protein interactions in amyloid-type protein fibril formation
    • Gorbenko GP, Kinnunen PK. 2006. The role of lipid-protein interactions in amyloid-type protein fibril formation. Chem Phys Lipids 141:72-82.
    • (2006) Chem Phys Lipids , vol.141 , pp. 72-82
    • Gorbenko, G.P.1    Kinnunen, P.K.2
  • 19
    • 33751221596 scopus 로고    scopus 로고
    • Increased cholesterol in Abeta-positive nerve terminals from Alzheimer's disease cortex
    • Gylys KH, Fein JA, Yang F, Miller CA, Cole GM. 2007. Increased cholesterol in Abeta-positive nerve terminals from Alzheimer's disease cortex. Neurobiol Aging 28:8-17.
    • (2007) Neurobiol Aging , vol.28 , pp. 8-17
    • Gylys, K.H.1    Fein, J.A.2    Yang, F.3    Miller, C.A.4    Cole, G.M.5
  • 20
    • 0037171006 scopus 로고    scopus 로고
    • Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice
    • Hayashi H, Igbavboa U, Hamanaka H, Kobayashi M, Fujita SC, Wood WG, Yanagisawa K. 2002. Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice. Neuroreport 13:383-386.
    • (2002) Neuroreport , vol.13 , pp. 383-386
    • Hayashi, H.1    Igbavboa, U.2    Hamanaka, H.3    Kobayashi, M.4    Fujita, S.C.5    Wood, W.G.6    Yanagisawa, K.7
  • 22
    • 84866430180 scopus 로고    scopus 로고
    • Lipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling
    • Hicks DA, Nalivaeva NN, Turner AJ. 2012. Lipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling. Front Physiol 3:189.
    • (2012) Front Physiol , vol.3 , pp. 189
    • Hicks, D.A.1    Nalivaeva, N.N.2    Turner, A.J.3
  • 23
    • 84863504256 scopus 로고    scopus 로고
    • Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease
    • Holtzman DM, Herz J, Bu G. 2012. Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harbor Perspect Med 2:a006312.
    • (2012) Cold Spring Harbor Perspect Med , vol.2
    • Holtzman, D.M.1    Herz, J.2    Bu, G.3
  • 24
    • 0029935694 scopus 로고    scopus 로고
    • Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice
    • Igbavboa U, Avdulov NA, Schroeder F, Wood WG. 1996. Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice. J Neurochem 66:1717-1725.
    • (1996) J Neurochem , vol.66 , pp. 1717-1725
    • Igbavboa, U.1    Avdulov, N.A.2    Schroeder, F.3    Wood, W.G.4
  • 25
    • 0035816709 scopus 로고    scopus 로고
    • Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid
    • Kakio A, Nishimoto SI, Yanagisawa K, Kozutsumi Y, Matsuzaki K. 2001. Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid. J Biol Chem 276:24985-24990.
    • (2001) J Biol Chem , vol.276 , pp. 24985-24990
    • Kakio, A.1    Nishimoto, S.I.2    Yanagisawa, K.3    Kozutsumi, Y.4    Matsuzaki, K.5
  • 27
    • 22744437388 scopus 로고    scopus 로고
    • Detergent-resistant membranes should not be identified with membrane rafts
    • Lichtenberg D, Goñi FM, Heerklotz H. 2005. Detergent-resistant membranes should not be identified with membrane rafts. Trends Biochem Sci 30:430-436.
    • (2005) Trends Biochem Sci , vol.30 , pp. 430-436
    • Lichtenberg, D.1    Goñi, F.M.2    Heerklotz, H.3
  • 28
    • 38449114971 scopus 로고    scopus 로고
    • Detergent resistance as a tool in membrane research
    • Lingwood D, Simons K. 2007. Detergent resistance as a tool in membrane research. Nat Protoc 2:2159-2165.
    • (2007) Nat Protoc , vol.2 , pp. 2159-2165
    • Lingwood, D.1    Simons, K.2
  • 29
  • 30
    • 84873722367 scopus 로고    scopus 로고
    • Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
    • Liu CC, Kanekiyo T, Xu H, Bu G. 2013. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol 9:106-118.
    • (2013) Nat Rev Neurol , vol.9 , pp. 106-118
    • Liu, C.C.1    Kanekiyo, T.2    Xu, H.3    Bu, G.4
  • 31
    • 77953235479 scopus 로고    scopus 로고
    • Abeta polymerization through interaction with membrane gangliosides
    • Matsuzaki K, Kato K, Yanagisawa K. 2010. Abeta polymerization through interaction with membrane gangliosides. Biochim Biophys Acta 1801:868-877.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 868-877
    • Matsuzaki, K.1    Kato, K.2    Yanagisawa, K.3
  • 32
    • 0033968648 scopus 로고    scopus 로고
    • Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture
    • Michikawa M, Fan QW, Isobe I, Yanagisawa K. 2000. Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J Neurochem 74:1008-1016.
    • (2000) J Neurochem , vol.74 , pp. 1008-1016
    • Michikawa, M.1    Fan, Q.W.2    Isobe, I.3    Yanagisawa, K.4
  • 33
    • 13244272410 scopus 로고    scopus 로고
    • Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains
    • Molander-Melin M, Blennow K, Bogdanovic N, Dellheden B, Månsson JE, Fredman P. 2005. Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains. J Neurochem 92:171-182.
    • (2005) J Neurochem , vol.92 , pp. 171-182
    • Molander-Melin, M.1    Blennow, K.2    Bogdanovic, N.3    Dellheden, B.4    Månsson, J.E.5    Fredman, P.6
  • 35
    • 0028787064 scopus 로고
    • Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease
    • Nagy Z, Esiri MM, Jobst KA, Johnston C, Litchfield S, Sim E, Smith AD. 1995. Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease. Neuroscience 69:757-761.
    • (1995) Neuroscience , vol.69 , pp. 757-761
    • Nagy, Z.1    Esiri, M.M.2    Jobst, K.A.3    Johnston, C.4    Litchfield, S.5    Sim, E.6    Smith, A.D.7
  • 36
    • 84865311604 scopus 로고    scopus 로고
    • The γ-secretase inhibitor DAPT increases the levels of gangliosides at neuritic terminals of differentiating PC12 cells
    • Oikawa N, Goto M, Ikeda K, Taguchi R, Yanagisawa K. 2012. The γ-secretase inhibitor DAPT increases the levels of gangliosides at neuritic terminals of differentiating PC12 cells. Neurosci Lett 525:49-53.
    • (2012) Neurosci Lett , vol.525 , pp. 49-53
    • Oikawa, N.1    Goto, M.2    Ikeda, K.3    Taguchi, R.4    Yanagisawa, K.5
  • 37
    • 0016681223 scopus 로고
    • The brain ganglioside pattern in presenile and senile dementia
    • Op Den Velde W, Hooghwinkel GJ. 1975. The brain ganglioside pattern in presenile and senile dementia. J Am Geriatr Soc 23:301-303.
    • (1975) J Am Geriatr Soc , vol.23 , pp. 301-303
    • Op Den Velde, W.1    Hooghwinkel, G.J.2
  • 38
    • 0028946291 scopus 로고
    • Apolipoprotein E genotype, Alzheimer's pathologies and related gene expression in the aged population
    • Oyama F, Shimada H, Oyama R, Ihara Y. 1995. Apolipoprotein E genotype, Alzheimer's pathologies and related gene expression in the aged population. Brain Res Mol Brain Res 29:92-98.
    • (1995) Brain Res Mol Brain Res , vol.29 , pp. 92-98
    • Oyama, F.1    Shimada, H.2    Oyama, R.3    Ihara, Y.4
  • 39
    • 67449168508 scopus 로고    scopus 로고
    • Isolation of rafts from mouse brain tissue by a detergent-free method
    • Persaud-Sawin DA, Lightcap S, Harry GJ. 2009. Isolation of rafts from mouse brain tissue by a detergent-free method. J Lipid Res 50:759-767.
    • (2009) J Lipid Res , vol.50 , pp. 759-767
    • Persaud-Sawin, D.A.1    Lightcap, S.2    Harry, G.J.3
  • 41
    • 0026042933 scopus 로고
    • Deposition of beta/A4 protein along neuronal plasma membranes in diffuse senile plaques
    • Probst A, Langui D, Ipsen S, Robakis N, Ulrich J. 1991. Deposition of beta/A4 protein along neuronal plasma membranes in diffuse senile plaques. Acta Neuropathol 83:21-29.
    • (1991) Acta Neuropathol , vol.83 , pp. 21-29
    • Probst, A.1    Langui, D.2    Ipsen, S.3    Robakis, N.4    Ulrich, J.5
  • 42
    • 33744991531 scopus 로고    scopus 로고
    • Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes
    • Rapp A, Gmeiner B, Hüttinger M. 2006. Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes. Biochimie 88:473-483.
    • (2006) Biochimie , vol.88 , pp. 473-483
    • Rapp, A.1    Gmeiner, B.2    Hüttinger, M.3
  • 44
    • 79952180064 scopus 로고    scopus 로고
    • Lipid rafts: linking Alzheimer's amyloid-β production, aggregation, and toxicity at neuronal membranes
    • Rushworth JV, Hooper NM. 2010. Lipid rafts: linking Alzheimer's amyloid-β production, aggregation, and toxicity at neuronal membranes. Int J Alzheimers Dis 2011:603052.
    • (2010) Int J Alzheimers Dis , vol.2011 , pp. 603052
    • Rushworth, J.V.1    Hooper, N.M.2
  • 46
    • 2942536666 scopus 로고    scopus 로고
    • Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease
    • Tiraboschi P, Hansen LA, Masliah E, Alford M, Thal LJ, Corey-Bloom J. 2004. Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease. Neurology 62:1977-1983.
    • (2004) Neurology , vol.62 , pp. 1977-1983
    • Tiraboschi, P.1    Hansen, L.A.2    Masliah, E.3    Alford, M.4    Thal, L.J.5    Corey-Bloom, J.6
  • 48
    • 55749095544 scopus 로고    scopus 로고
    • Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid beta-protein fibrillogenesis
    • Yamamoto N, Matsubara T, Sato T, Yanagisawa K. 2008. Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid beta-protein fibrillogenesis. Biochim Biophys Acta 1778:2717-2726.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 2717-2726
    • Yamamoto, N.1    Matsubara, T.2    Sato, T.3    Yanagisawa, K.4
  • 49
    • 34547152918 scopus 로고    scopus 로고
    • Role of gangliosides in Alzheimer's disease
    • Yanagisawa K. 2007. Role of gangliosides in Alzheimer's disease. Biochim Biophys Acta 1768:1943-1951.
    • (2007) Biochim Biophys Acta , vol.1768 , pp. 1943-1951
    • Yanagisawa, K.1
  • 50
    • 0028885854 scopus 로고
    • GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease
    • Yanagisawa K, Odaka A, Suzuki N, Ihara Y. 1995. GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease. Nat Med 1:1062-1066.
    • (1995) Nat Med , vol.1 , pp. 1062-1066
    • Yanagisawa, K.1    Odaka, A.2    Suzuki, N.3    Ihara, Y.4


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