-
2
-
-
27844472511
-
Causes of cancer in the world: Comparative risk assessment of nine behavioural and environmental risk factors
-
Danaei G, Vander Hoorn S, Lopez AD, et al. Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factors. Lancet. 2005;366:1784-1793.
-
(2005)
Lancet
, vol.366
, pp. 1784-1793
-
-
Danaei, G.1
Vander Hoorn, S.2
Lopez, A.D.3
-
3
-
-
33845680235
-
Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: A casecontrol study
-
McLaughlin JR, Risch HA, Lubinski J, et al. Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a casecontrol study. Lancet Oncol. 2007;8:26-34.
-
(2007)
Lancet Oncol
, vol.8
, pp. 26-34
-
-
McLaughlin, J.R.1
Risch, H.A.2
Lubinski, J.3
-
4
-
-
33845338724
-
Projections of global mortality and burden of disease from 2002 to 2030
-
Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3:e442.
-
(2006)
PLoS Med
, vol.3
-
-
Mathers, C.D.1
Loncar, D.2
-
5
-
-
5444260703
-
Genetic alterations and DNA repair in human carcinogenesis
-
Dixon K, Kopras E. Genetic alterations and DNA repair in human carcinogenesis. Semin Cancer Biol. 2004;14:441-448.
-
(2004)
Semin Cancer Biol
, vol.14
, pp. 441-448
-
-
Dixon, K.1
Kopras, E.2
-
6
-
-
40549130342
-
CDC6: From DNA replication to cell cycle checkpoints and oncogenesis
-
Borlado LR, Mendez J. CDC6: from DNA replication to cell cycle checkpoints and oncogenesis. Carcinogenesis. 2008;29:237-243.
-
(2008)
Carcinogenesis
, vol.29
, pp. 237-243
-
-
Borlado, L.R.1
Mendez, J.2
-
7
-
-
0034985546
-
E-cadherin, beta-catenin and cadmium carcinogenesis
-
Pearson CA, Prozialeck WC. E-cadherin, beta-catenin and cadmium carcinogenesis. Med Hypotheses. 2001;56:573-581.
-
(2001)
Med Hypotheses
, vol.56
, pp. 573-581
-
-
Pearson, C.A.1
Prozialeck, W.C.2
-
8
-
-
11844299802
-
From spindle checkpoint to cancer
-
Lengauer C, Wang Z. From spindle checkpoint to cancer. Nat Genet. 2004;36:1144-1145.
-
(2004)
Nat Genet
, vol.36
, pp. 1144-1145
-
-
Lengauer, C.1
Wang, Z.2
-
9
-
-
10644258336
-
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
-
Hanks S, Coleman K, Reid S, et al. Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat Genet. 2004;36:1159-1161.
-
(2004)
Nat Genet
, vol.36
, pp. 1159-1161
-
-
Hanks, S.1
Coleman, K.2
Reid, S.3
-
10
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
11
-
-
0035953308
-
IFNgamma and lymphocytes prevent primary tumor development and shape tumor immunogenicity
-
Shankaran V, Ikeda H, Bruce AT, et al. IFNgamma and lymphocytes prevent primary tumor development and shape tumor immunogenicity. Nature. 2001;410:1107-1111.
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
-
12
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
Dunn GP, Bruce AT, Ikeda H, et al. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol. 2002;3: 991-998.
-
(2002)
Nat Immunol
, vol.3
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
-
14
-
-
79953151458
-
Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
-
Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science. 2011; 331:1565-1570.
-
(2011)
Science
, vol.331
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
15
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer. 2007;7:834-846.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
16
-
-
77949449775
-
The incidence, natural history, biology, and treatment of transformed lymphomas
-
Bernstein SH, Burack WR. The incidence, natural history, biology, and treatment of transformed lymphomas. Hematology Am Soc Hematol Educ Program. 2009:532-541.
-
(2009)
Hematology Am Soc Hematol Educ Program
, pp. 532-541
-
-
Bernstein, S.H.1
Burack, W.R.2
-
19
-
-
79959190996
-
Chemoimmunotherapy with ofatumumab, fludarabine, and cyclophosphamide (O-FC) in previously untreated patients with chronic lymphocytic leukemia
-
Wierda WG, Kipps TJ, Durig J, et al. Chemoimmunotherapy with ofatumumab, fludarabine, and cyclophosphamide (O-FC) in previously untreated patients with chronic lymphocytic leukemia. Blood. 2011;117: 6450-6458.
-
(2011)
Blood
, vol.117
, pp. 6450-6458
-
-
Wierda, W.G.1
Kipps, T.J.2
Durig, J.3
-
20
-
-
79551568488
-
Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study
-
Stopeck AT, Lipton A, Body JJ, et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. J Clin Oncol. 2010;28:5132-5139.
-
(2010)
J Clin Oncol
, vol.28
, pp. 5132-5139
-
-
Stopeck, A.T.1
Lipton, A.2
Body, J.J.3
-
22
-
-
77950986756
-
Gemcitabine versus bacille Calmette-Guerin after initial bacille Calmette-Guerin failure in nonmuscle-invasive bladder cancer: A multicenter prospective randomized trial
-
Di Lorenzo G, Perdona S, Damiano R, et al. Gemcitabine versus bacille Calmette-Guerin after initial bacille Calmette-Guerin failure in nonmuscle-invasive bladder cancer: a multicenter prospective randomized trial. Cancer. 2010;116:1893-1900.
-
(2010)
Cancer
, vol.116
, pp. 1893-1900
-
-
di Lorenzo, G.1
Perdona, S.2
Damiano, R.3
-
23
-
-
77957191110
-
Antitumoral immunity by virusmediated immunogenic apoptosis inhibits metastatic growth of hepatocellular carcinoma
-
Boozari B, Mundt B, Woller N, et al. Antitumoral immunity by virusmediated immunogenic apoptosis inhibits metastatic growth of hepatocellular carcinoma. Gut. 2010;59:1416-1426.
-
(2010)
Gut
, vol.59
, pp. 1416-1426
-
-
Boozari, B.1
Mundt, B.2
Woller, N.3
-
24
-
-
38449089187
-
Adjuvant therapy with high-dose interferon alpha 2b in patients with high-risk stage IIB/III melanoma
-
Kirkwood JM, Tarhini AA, Moschos SJ, Panelli MC. Adjuvant therapy with high-dose interferon alpha 2b in patients with high-risk stage IIB/III melanoma. Nat Clin Pract Oncol. 2008;5:2-3.
-
(2008)
Nat Clin Pract Oncol
, vol.5
, pp. 2-3
-
-
Kirkwood, J.M.1
Tarhini, A.A.2
Moschos, S.J.3
Panelli, M.C.4
-
25
-
-
0033848628
-
High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update
-
Atkins MB, Kunkel L, Sznol M, Rosenberg SA. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am. 2000;6(Suppl 1):S11-S14.
-
(2000)
Cancer J Sci Am
, vol.6
, Issue.SUPPL. 1
-
-
Atkins, M.B.1
Kunkel, L.2
Sznol, M.3
Rosenberg, S.A.4
-
26
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
-
Atkins MB, Lotze MT, Dutcher JP, et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol. 1999;17: 2105-2116.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
-
27
-
-
78149358809
-
Randomized phase III trial of tamoxifen versus thalidomide in women with biochemical-recurrentonly epithelial ovarian, fallopian tube or primary peritoneal carcinoma after a complete response to first-line platinum/taxane chemotherapy with an evaluation of serum vascular endothelial growth factor (VEGF): A Gynecologic Oncology Group Study
-
Hurteau JA, Brady MF, Darcy KM, et al. Randomized phase III trial of tamoxifen versus thalidomide in women with biochemical-recurrentonly epithelial ovarian, fallopian tube or primary peritoneal carcinoma after a complete response to first-line platinum/taxane chemotherapy with an evaluation of serum vascular endothelial growth factor (VEGF): a Gynecologic Oncology Group Study. Gynecol Oncol. 2010; 119:444-450.
-
(2010)
Gynecol Oncol
, vol.119
, pp. 444-450
-
-
Hurteau, J.A.1
Brady, M.F.2
Darcy, K.M.3
-
28
-
-
79960299888
-
Durable complete responses in heavily pretreted patients with metastatic melanoma using T cell transfer immunotherapy
-
April 15, Epub ahead of print
-
Rosenberg SA, Yang JC, Sherry RM, et al. Durable complete responses in heavily pretreted patients with metastatic melanoma using T cell transfer immunotherapy. Clin Cancer Res. April 15, 2011. [Epub ahead of print.].
-
(2011)
Clin Cancer Res
-
-
Rosenberg, S.A.1
Yang, J.C.2
Sherry, R.M.3
-
29
-
-
65249173447
-
Adoptive cell therapy for the treatment of patients with metastatic melanoma
-
Rosenberg SA, Dudley ME. Adoptive cell therapy for the treatment of patients with metastatic melanoma. Curr Opin Immunol. 2009;21: 233-240.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 233-240
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
30
-
-
34248204110
-
DC-based cancer vaccines
-
Gilboa E. DC-based cancer vaccines. J Clin Invest. 2007;117: 1195-1203.
-
(2007)
J Clin Invest
, vol.117
, pp. 1195-1203
-
-
Gilboa, E.1
-
31
-
-
34547475142
-
Vaccination with NYESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming
-
Valmori D, Souleimanian NE, Tosello V, et al. Vaccination with NYESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming. Proc Natl Acad Sci U S A. 2007;104:8947-8952.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 8947-8952
-
-
Valmori, D.1
Souleimanian, N.E.2
Tosello, V.3
-
32
-
-
45849113567
-
Preclinical safety pharmacology study of a novel protein-based cancer vaccine CHP-NY-ESO-1
-
Harada N, Hoshiai K, Takahashi Y, et al. Preclinical safety pharmacology study of a novel protein-based cancer vaccine CHP-NY-ESO-1. Kobe J Med Sci. 2008;54:E23-E34.
-
(2008)
Kobe J Med Sci
, vol.54
-
-
Harada, N.1
Hoshiai, K.2
Takahashi, Y.3
-
33
-
-
34547915603
-
Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer
-
Odunsi K, Qian F, Matsuzaki J, et al. Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer. Proc Natl Acad Sci U S A. 2007;104: 12837-12842.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12837-12842
-
-
Odunsi, K.1
Qian, F.2
Matsuzaki, J.3
-
34
-
-
62449213245
-
NY-ESO-1 DNA vaccine induces T-cell responses that are suppressed by regulatory T cells
-
Gnjatic S, Altorki NK, Tang DN, et al. NY-ESO-1 DNA vaccine induces T-cell responses that are suppressed by regulatory T cells. Clin Cancer Res. 2009;15:2130-2139.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2130-2139
-
-
Gnjatic, S.1
Altorki, N.K.2
Tang, D.N.3
-
35
-
-
33745832268
-
In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines
-
Nishikawa H, Sato E, Briones G, et al. In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines. J Clin Invest. 2006;116:1946-1954.
-
(2006)
J Clin Invest
, vol.116
, pp. 1946-1954
-
-
Nishikawa, H.1
Sato, E.2
Briones, G.3
-
36
-
-
33749237126
-
Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients
-
Jager E, Karbach J, Gnjatic S, et al. Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients. Proc Natl Acad Sci U S A. 2006;103:14453-14458.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14453-14458
-
-
Jager, E.1
Karbach, J.2
Gnjatic, S.3
-
37
-
-
58149186474
-
CT database: A knowledge-base of high-throughput and curated data on cancer-testis antigens
-
(database issue)
-
Almeida LG, Sakabe NJ, deOliveira AR, et al. CT database: a knowledge-base of high-throughput and curated data on cancer-testis antigens. Nucleic Acids Res. 2009;37(database issue):D816-D819.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Almeida, L.G.1
Sakabe, N.J.2
Deoliveira, A.R.3
-
38
-
-
71049153709
-
Cancer/testis (CT) antigens: Potential targets for immunotherapy
-
Caballero OL, Chen YT. Cancer/testis (CT) antigens: potential targets for immunotherapy. Cancer Sci. 2009;100:2014-2021.
-
(2009)
Cancer Sci
, vol.100
, pp. 2014-2021
-
-
Caballero, O.L.1
Chen, Y.T.2
-
39
-
-
34748815649
-
GSK's antigen-specific cancer immunotherapy programme: Pilot results leading to phase III clinical development
-
Brichard VG, Lejeune D. GSK's antigen-specific cancer immunotherapy programme: pilot results leading to phase III clinical development. Vaccine. 2007;25(Suppl 2):B61-B71.
-
(2007)
Vaccine
, vol.25
, Issue.SUPPL. 2
-
-
Brichard, V.G.1
Lejeune, D.2
-
41
-
-
3242658810
-
Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4(+) and CD8(+) T cell responses in humans
-
Davis ID, Chen W, Jackson H, et al. Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4(+) and CD8(+) T cell responses in humans. Proc Natl Acad Sci U S A. 2004;101:10697-10702.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10697-10702
-
-
Davis, I.D.1
Chen, W.2
Jackson, H.3
-
42
-
-
0033579934
-
Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1
-
Marchand M, van Baren N, Weynants P, et al. Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. Int J Cancer. 1999;80:219-230.
-
(1999)
Int J Cancer
, vol.80
, pp. 219-230
-
-
Marchand, M.1
van Baren, N.2
Weynants, P.3
-
43
-
-
77956779733
-
Tumor microenvironment and immune effects of antineoplastic therapy in lymphoproliferative syndromes
-
August 12, Epub ahead of print
-
Alvaro T, de la Cruz-Merino L, Henao-Carrasco F, et al. Tumor microenvironment and immune effects of antineoplastic therapy in lymphoproliferative syndromes. J Biomed Biotechnol. August 12, 2010. [Epub ahead of print.].
-
(2010)
J Biomed Biotechnol
-
-
Alvaro, T.1
de la Cruz-Merino, L.2
Henao-Carrasco, F.3
-
44
-
-
67650236125
-
A llama single domain anti-idiotypic antibody mimicking HER2 as a vaccine: Immunogenicity and efficacy
-
Alvarez-Rueda N, Ladjemi MZ, Behar G, et al. A llama single domain anti-idiotypic antibody mimicking HER2 as a vaccine: Immunogenicity and efficacy. Vaccine. 2009;27:4826-4833.
-
(2009)
Vaccine
, vol.27
, pp. 4826-4833
-
-
Alvarez-Rueda, N.1
Ladjemi, M.Z.2
Behar, G.3
-
45
-
-
33646191029
-
Monoclonal antibodies in the treatment of lung cancer
-
Egri G, Takats A. Monoclonal antibodies in the treatment of lung cancer. Eur J Surg Oncol. 2006;32:385-394.
-
(2006)
Eur J Surg Oncol
, vol.32
, pp. 385-394
-
-
Egri, G.1
Takats, A.2
-
46
-
-
79251555315
-
Recent developments in cancer vaccines
-
Palucka K, Ueno H, Banchereau J. Recent developments in cancer vaccines. J Immunol. 2011;186:1325-1331.
-
(2011)
J Immunol
, vol.186
, pp. 1325-1331
-
-
Palucka, K.1
Ueno, H.2
Banchereau, J.3
-
47
-
-
0345447557
-
Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
-
Nair S, McLaughlin C, Weizer A, et al. Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J Immunol. 2003;171:6275-6282.
-
(2003)
J Immunol
, vol.171
, pp. 6275-6282
-
-
Nair, S.1
McLaughlin, C.2
Weizer, A.3
-
48
-
-
0042922810
-
Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming
-
Martin-Fontecha A, Sebastiani S, Hopken UE, et al. Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med. 2003;198:615-621.
-
(2003)
J Exp Med
, vol.198
, pp. 615-621
-
-
Martin-Fontecha, A.1
Sebastiani, S.2
Hopken, U.E.3
-
49
-
-
77956122616
-
Dendritic cells in cancer immunotherapy
-
Schuler G. Dendritic cells in cancer immunotherapy. Eur J Immunol. 2010;40:2123-2130.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2123-2130
-
-
Schuler, G.1
-
50
-
-
79955630348
-
Engineering dendritic cells to enhance cancer immunotherapy
-
Boudreau JE, Bonehill A, Thielemans K, Wan Y. Engineering dendritic cells to enhance cancer immunotherapy. Mol Ther. 2011;19: 841-853.
-
(2011)
Mol Ther
, vol.19
, pp. 841-853
-
-
Boudreau, J.E.1
Bonehill, A.2
Thielemans, K.3
Wan, Y.4
-
51
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010;363: 411-422.
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
52
-
-
78149236593
-
The first dendritic cell-based therapeutic cancer vaccine is approved by the FDA
-
Hovden AO, Appel S. The first dendritic cell-based therapeutic cancer vaccine is approved by the FDA. Scand J Immunol. 2010;72:554.
-
(2010)
Scand J Immunol
, vol.72
, pp. 554
-
-
Hovden, A.O.1
Appel, S.2
-
53
-
-
77958570368
-
Gene-modified cellular vaccines: Technologic aspects and clinical problems
-
Mackiewicz J, Mackiewicz A. Gene-modified cellular vaccines: technologic aspects and clinical problems. Transplant Proc. 2010;42: 3287-3292.
-
(2010)
Transplant Proc
, vol.42
, pp. 3287-3292
-
-
Mackiewicz, J.1
Mackiewicz, A.2
-
54
-
-
77951847280
-
Combination strategies for enhancing the efficacy of immunotherapy in cancer patients
-
Moschella F, Proietti E, Capone I, Belardelli F. Combination strategies for enhancing the efficacy of immunotherapy in cancer patients. Ann N Y Acad Sci. 2010;1194:169-178.
-
(2010)
Ann N Y Acad Sci
, vol.1194
, pp. 169-178
-
-
Moschella, F.1
Proietti, E.2
Capone, I.3
Belardelli, F.4
-
55
-
-
33751209215
-
Combined chemoimmunotherapy of solid tumors: Improving vaccines?
-
Nowak AK, Lake RA, Robinson BW. Combined chemoimmunotherapy of solid tumors: improving vaccines? Adv Drug Deliv Rev. 2006;58: 975-990.
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 975-990
-
-
Nowak, A.K.1
Lake, R.A.2
Robinson, B.W.3
-
56
-
-
79956085853
-
Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide
-
Moschella F, Valentini M, Arico E, et al. Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide. Cancer Res. 2011;71:3528-3539.
-
(2011)
Cancer Res
, vol.71
, pp. 3528-3539
-
-
Moschella, F.1
Valentini, M.2
Arico, E.3
-
57
-
-
74549124884
-
Combining low-dose cyclophosphamide with GM-CSF-secreting prostate cancer immunotherapy enhances antitumor immune effects
-
Antonarakis ES, Carducci MA. Combining low-dose cyclophosphamide with GM-CSF-secreting prostate cancer immunotherapy enhances antitumor immune effects. Expert Opin Investig Drugs. 2010; 19:311-314.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 311-314
-
-
Antonarakis, E.S.1
Carducci, M.A.2
-
58
-
-
79955118680
-
Combination of epitope-optimized DNA vaccination and passive infusion of monoclonal antibody against HER2/neu leads to breast tumor regression in mice
-
Orlandi F, Guevara-Patino JA, Merghoub T, et al. Combination of epitope-optimized DNA vaccination and passive infusion of monoclonal antibody against HER2/neu leads to breast tumor regression in mice. Vaccine. 2011;29:3646-3654.
-
(2011)
Vaccine
, vol.29
, pp. 3646-3654
-
-
Orlandi, F.1
Guevara-Patino, J.A.2
Merghoub, T.3
-
59
-
-
84860389330
-
Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice
-
Ladjemi MZ, Chardes T, Corgnac S, et al. Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice. Breast Cancer Res. 2011;13:R17.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Ladjemi, M.Z.1
Chardes, T.2
Corgnac, S.3
-
60
-
-
79955489170
-
Intra-lymph node primeboost vaccination against melan A and tyrosinase for the treatment of metastatic melanoma: Results of a phase 1 clinical trial
-
Ribas A, Weber JS, Chmielowski B, et al. Intra-lymph node primeboost vaccination against melan A and tyrosinase for the treatment of metastatic melanoma: results of a phase 1 clinical trial. Clin Cancer Res. 2011;17:2987-2996.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2987-2996
-
-
Ribas, A.1
Weber, J.S.2
Chmielowski, B.3
-
61
-
-
78149466672
-
Addition of adenoviral vector targeting of chemotherapy to the MUC-1/ecdCD40L VPPP vector prime protein boost vaccine prolongs survival of mice carrying growing subcutaneous deposits of Lewis lung cancer cells
-
Akbulut H, Tang Y, Akbulut KG, et al. Addition of adenoviral vector targeting of chemotherapy to the MUC-1/ecdCD40L VPPP vector prime protein boost vaccine prolongs survival of mice carrying growing subcutaneous deposits of Lewis lung cancer cells. Gene Ther. 2010; 17:1333-1340.
-
(2010)
Gene Ther
, vol.17
, pp. 1333-1340
-
-
Akbulut, H.1
Tang, Y.2
Akbulut, K.G.3
-
62
-
-
77954959459
-
Heterologous prime/boost immunization with p53-based vaccines combined with toll-like receptor stimulation enhances tumor regression
-
Ishizaki H, Song GY, Srivastava T, et al. Heterologous prime/boost immunization with p53-based vaccines combined with toll-like receptor stimulation enhances tumor regression. J Immunother. 2010;33: 609-617.
-
(2010)
J Immunother
, vol.33
, pp. 609-617
-
-
Ishizaki, H.1
Song, G.Y.2
Srivastava, T.3
-
63
-
-
77953098156
-
Clinical and immunological responses in metastatic melanoma patients vaccinated with a highdose poly-epitope vaccine
-
Dangoor A, Lorigan P, Keilholz U, et al. Clinical and immunological responses in metastatic melanoma patients vaccinated with a highdose poly-epitope vaccine. Cancer Immunol Immunother. 2010;59: 863-873.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 863-873
-
-
Dangoor, A.1
Lorigan, P.2
Keilholz, U.3
-
64
-
-
67649340803
-
Harnessing the unique local immunostimulatory properties of modified vaccinia Ankara (MVA) virus to generate superior tumor-specific immune responses and antitumor activity in a diversified prime and boost vaccine regimen
-
Hodge JW, Higgins J, Schlom J. Harnessing the unique local immunostimulatory properties of modified vaccinia Ankara (MVA) virus to generate superior tumor-specific immune responses and antitumor activity in a diversified prime and boost vaccine regimen. Vaccine. 2009;27:4475-4482.
-
(2009)
Vaccine
, vol.27
, pp. 4475-4482
-
-
Hodge, J.W.1
Higgins, J.2
Schlom, J.3
-
65
-
-
77649270825
-
Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and costimulatory molecules in metastatic melanoma
-
Adamina M, Rosenthal R, Weber WP, et al. Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and costimulatory molecules in metastatic melanoma. Mol Ther. 2010;18: 651-659.
-
(2010)
Mol Ther
, vol.18
, pp. 651-659
-
-
Adamina, M.1
Rosenthal, R.2
Weber, W.P.3
-
66
-
-
67650648498
-
Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer
-
Kono K, Mizukami Y, Daigo Y, et al. Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer. Cancer Sci. 2009;100:1502-1509.
-
(2009)
Cancer Sci
, vol.100
, pp. 1502-1509
-
-
Kono, K.1
Mizukami, Y.2
Daigo, Y.3
-
67
-
-
33947245441
-
History of oncolytic viruses: Genesis to genetic engineering
-
Kelly E, Russell SJ. History of oncolytic viruses: genesis to genetic engineering. Mol Ther. 2007;15:651-659.
-
(2007)
Mol Ther
, vol.15
, pp. 651-659
-
-
Kelly, E.1
Russell, S.J.2
-
68
-
-
1642430137
-
The destructive effect of the virus of Russian Far East encephalitis on the transplantable mouse sarcoma 180
-
Moore AE. The destructive effect of the virus of Russian Far East encephalitis on the transplantable mouse sarcoma 180. Cancer. 1949;2: 525-534.
-
(1949)
Cancer
, vol.2
, pp. 525-534
-
-
Moore, A.E.1
-
69
-
-
0343976881
-
Inhibition of growth of five transplantable mouse tumors by the virus of Russian Far East encephalitis
-
Moore AE. Inhibition of growth of five transplantable mouse tumors by the virus of Russian Far East encephalitis. Cancer. 1951;4:375-382.
-
(1951)
Cancer
, vol.4
, pp. 375-382
-
-
Moore, A.E.1
-
70
-
-
0025864440
-
Experimental therapy of human glioma by means of a genetically engineered virus mutant
-
Martuza RL, Malick A, Markert JM, et al. Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science. 1991;252:854-856.
-
(1991)
Science
, vol.252
, pp. 854-856
-
-
Martuza, R.L.1
Malick, A.2
Markert, J.M.3
-
71
-
-
77952311664
-
Oncolytic viruses move forward in clinical trials
-
Rowan K. Oncolytic viruses move forward in clinical trials. J Natl Cancer Inst. 2010;102:590-595.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 590-595
-
-
Rowan, K.1
-
72
-
-
33644852717
-
China approves world's first oncolytic virus therapy for cancer treatment
-
Garber K. China approves world's first oncolytic virus therapy for cancer treatment. J Natl Cancer Inst. 2006;98:298-300.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 298-300
-
-
Garber, K.1
-
73
-
-
79952945559
-
Oncolytic adenoviruses for the treatment of human cancer: Focus on translational and clinical data
-
Pesonen S, Kangasniemi L, Hemminki A. Oncolytic adenoviruses for the treatment of human cancer: focus on translational and clinical data. Mol Pharm. 2011;8:12-28.
-
(2011)
Mol Pharm
, vol.8
, pp. 12-28
-
-
Pesonen, S.1
Kangasniemi, L.2
Hemminki, A.3
-
74
-
-
70449130491
-
Characterization of human adenovirus serotypes 5, 6, 11, and 35 as anticancer agents
-
Shashkova EV, May SM, Barry MA. Characterization of human adenovirus serotypes 5, 6, 11, and 35 as anticancer agents. Virology. 2009;394:311-320.
-
(2009)
Virology
, vol.394
, pp. 311-320
-
-
Shashkova, E.V.1
May, S.M.2
Barry, M.A.3
-
76
-
-
79953043411
-
Transduction and oncolytic profile of a potent replication-competent adenovirus 11p vector (RCAd11pGFP) in colon carcinoma cells
-
Silver J, Mei YF. Transduction and oncolytic profile of a potent replication-competent adenovirus 11p vector (RCAd11pGFP) in colon carcinoma cells. PLoS One. 2011;6:e17532.
-
(2011)
PLoS One
, vol.6
-
-
Silver, J.1
Mei, Y.F.2
-
77
-
-
77957253429
-
OPTIM trial: A phase III trial of an oncolytic herpes virus encoding GM-CSF for unresectable stage III or IV melanoma
-
Kaufman HL, Bines SD. OPTIM trial: a phase III trial of an oncolytic herpes virus encoding GM-CSF for unresectable stage III or IV melanoma. Future Oncol. 2010;6:941-949.
-
(2010)
Future Oncol
, vol.6
, pp. 941-949
-
-
Kaufman, H.L.1
Bines, S.D.2
-
78
-
-
34548020722
-
Coadministration of a herpes simplex virus-2 based oncolytic virus and cyclophosphamide produces a synergistic antitumor effect and enhances tumor-specific immune responses
-
Li H, Zeng Z, Fu X, Zhang X. Coadministration of a herpes simplex virus-2 based oncolytic virus and cyclophosphamide produces a synergistic antitumor effect and enhances tumor-specific immune responses. Cancer Res. 2007;67:7850-7855.
-
(2007)
Cancer Res
, vol.67
, pp. 7850-7855
-
-
Li, H.1
Zeng, Z.2
Fu, X.3
Zhang, X.4
-
79
-
-
33846288312
-
Virotherapy with a type 2 herpes simplex virus-derived oncolytic virus induces potent antitumor immunity against neuroblastoma
-
Li H, Dutuor A, Tao L, et al. Virotherapy with a type 2 herpes simplex virus-derived oncolytic virus induces potent antitumor immunity against neuroblastoma. Clin Cancer Res. 2007;13:316-322.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 316-322
-
-
Li, H.1
Dutuor, A.2
Tao, L.3
-
81
-
-
33846007302
-
Development of a conditionally replicating pseudorabies virus for HER-2/neu-overexpressing bladder cancer therapy
-
Shiau AL, Lin YP, Shieh GS, et al. Development of a conditionally replicating pseudorabies virus for HER-2/neu-overexpressing bladder cancer therapy. Mol Ther. 2007;15:131-138.
-
(2007)
Mol Ther
, vol.15
, pp. 131-138
-
-
Shiau, A.L.1
Lin, Y.P.2
Shieh, G.S.3
-
82
-
-
78049321960
-
Bovine herpesvirus 4 based vector as a potential oncolytic-virus for treatment of glioma
-
Redaelli M, Mucignat-Caretta C, Cavaggioni A, et al. Bovine herpesvirus 4 based vector as a potential oncolytic-virus for treatment of glioma. Virol J. 2010;7:298.
-
(2010)
Virol J
, vol.7
, pp. 298
-
-
Redaelli, M.1
Mucignat-Caretta, C.2
Cavaggioni, A.3
-
83
-
-
0033949533
-
Specific oncolytic activity of herpesvirus saimiri in pancreatic cancer cells
-
August
-
Stevenson AJ, Giles MS, Hall KT, et al. Specific oncolytic activity of herpesvirus saimiri in pancreatic cancer cells. Br J Cancer. August 2000;83:329-332.
-
(2000)
Br J Cancer
, vol.83
, pp. 329-332
-
-
Stevenson, A.J.1
Giles, M.S.2
Hall, K.T.3
-
84
-
-
18144413065
-
Targeting human glioblastoma cells: Comparison of nine viruses with oncolytic potential
-
Wollmann G, Tattersall P, van den Pol AN. Targeting human glioblastoma cells: comparison of nine viruses with oncolytic potential. J Virol. 2005;79:6005-6022.
-
(2005)
J Virol
, vol.79
, pp. 6005-6022
-
-
Wollmann, G.1
Tattersall, P.2
van den Pol, A.N.3
-
85
-
-
80052406557
-
Intravenous delivery of a multimechanistic cancer-targeted oncolytic poxvirus in humans
-
Breitbach CJ, Burke J, Jonker D, et al. Intravenous delivery of a multimechanistic cancer-targeted oncolytic poxvirus in humans. Nature. 2011;477:99-102.
-
(2011)
Nature
, vol.477
, pp. 99-102
-
-
Breitbach, C.J.1
Burke, J.2
Jonker, D.3
-
86
-
-
77952009271
-
Potent oncolytic activity of raccoonpox virus in the absence of natural pathogenicity
-
Evgin L, Vaha-Koskela M, Rintoul J, et al. Potent oncolytic activity of raccoonpox virus in the absence of natural pathogenicity. Mol Ther. 2010;18:896-902.
-
(2010)
Mol Ther
, vol.18
, pp. 896-902
-
-
Evgin, L.1
Vaha-Koskela, M.2
Rintoul, J.3
-
87
-
-
76549086994
-
Myxoma virus virotherapy for glioma in immunocompetent animal models: Optimizing administration routes and synergy with rapamycin
-
Lun X, Alain T, Zemp FJ, et al. Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin. Cancer Res. 2010;70:598-608.
-
(2010)
Cancer Res
, vol.70
, pp. 598-608
-
-
Lun, X.1
Alain, T.2
Zemp, F.J.3
-
88
-
-
29744436387
-
Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody
-
Wurdinger T, Verheije MH, Raaben M, et al. Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody. Gene Ther. 2005;12:1394-1404.
-
(2005)
Gene Ther
, vol.12
, pp. 1394-1404
-
-
Wurdinger, T.1
Verheije, M.H.2
Raaben, M.3
-
89
-
-
67650885885
-
Coronavirus genetically redirected to the epidermal growth factor receptor exhibits effective antitumor activity against a malignant glioblastoma
-
Verheije MH, Lamfers ML, Wurdinger T, et al. Coronavirus genetically redirected to the epidermal growth factor receptor exhibits effective antitumor activity against a malignant glioblastoma. J Virol. 2009;83:7507-7516.
-
(2009)
J Virol
, vol.83
, pp. 7507-7516
-
-
Verheije, M.H.1
Lamfers, M.L.2
Wurdinger, T.3
-
90
-
-
77957117274
-
Endogenous expression of proteases in colon cancer cells facilitate influenza A viruses mediated oncolysis
-
Sturlan S, Stremitzer S, Bauman S, et al. Endogenous expression of proteases in colon cancer cells facilitate influenza A viruses mediated oncolysis. Cancer Biol Ther. 2010;10:592-599.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 592-599
-
-
Sturlan, S.1
Stremitzer, S.2
Bauman, S.3
-
91
-
-
76249123546
-
Phase I trial of intraperitoneal administration of an oncolytic measles virus strain engineered to express carcinoembryonic antigen for recurrent ovarian cancer
-
Galanis E, Hartmann LC, Cliby WA, et al. Phase I trial of intraperitoneal administration of an oncolytic measles virus strain engineered to express carcinoembryonic antigen for recurrent ovarian cancer. Cancer Res. 2010;70:875-882.
-
(2010)
Cancer Res
, vol.70
, pp. 875-882
-
-
Galanis, E.1
Hartmann, L.C.2
Cliby, W.A.3
-
92
-
-
77957607636
-
Urokinase-targeted fusion by oncolytic Sendai virus eradicates orthotopic glioblastomas by pronounced synergy with interferon-beta gene
-
Hasegawa Y, Kinoh H, Iwadate Y, et al. Urokinase-targeted fusion by oncolytic Sendai virus eradicates orthotopic glioblastomas by pronounced synergy with interferon-beta gene. Mol Ther. 2010;18: 1778-1786.
-
(2010)
Mol Ther
, vol.18
, pp. 1778-1786
-
-
Hasegawa, Y.1
Kinoh, H.2
Iwadate, Y.3
-
93
-
-
22044447066
-
Oncolytic activities of approved mumps and measles vaccines for therapy of ovarian cancer
-
Myers R, Greiner S, Harvey M, et al. Oncolytic activities of approved mumps and measles vaccines for therapy of ovarian cancer. Cancer Gene Ther. 2005;12:593-599.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 593-599
-
-
Myers, R.1
Greiner, S.2
Harvey, M.3
-
94
-
-
77956929126
-
Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus
-
Roos FC, Roberts AM, Hwang II, et al. Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus. EMBO Mol Med. 2010; 2:275-288.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 275-288
-
-
Roos, F.C.1
Roberts, A.M.2
Hwang, I.I.3
-
95
-
-
33748439147
-
Destruction of human retinoblastoma after treatment by the E variant of encephalomyocarditis virus
-
Adachi M, Brooks SE, Stein MR, et al. Destruction of human retinoblastoma after treatment by the E variant of encephalomyocarditis virus. J Neurooncol. 2006;77:233-240.
-
(2006)
J Neurooncol
, vol.77
, pp. 233-240
-
-
Adachi, M.1
Brooks, S.E.2
Stein, M.R.3
-
96
-
-
78651439839
-
Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18
-
Au GG, Beagley LG, Haley ES, et al. Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18. Virol J. 2011;8:22.
-
(2011)
Virol J
, vol.8
, pp. 22
-
-
Au, G.G.1
Beagley, L.G.2
Haley, E.S.3
-
97
-
-
78650809359
-
Oncolytic poliovirus therapy and immunization with poliovirus-infected cell lysate induces potent antitumor immunity against neuroblastoma in vivo
-
Toyoda H, Wimmer E, Cello J. Oncolytic poliovirus therapy and immunization with poliovirus-infected cell lysate induces potent antitumor immunity against neuroblastoma in vivo. Int J Oncol. 2011;38: 81-87.
-
(2011)
Int J Oncol
, vol.38
, pp. 81-87
-
-
Toyoda, H.1
Wimmer, E.2
Cello, J.3
-
98
-
-
64149131456
-
Regional administration of oncolytic Echovirus 1 as a novel therapy for the peritoneal dissemination of gastric cancer
-
Haley ES, Au GG, Carlton BR, et al. Regional administration of oncolytic Echovirus 1 as a novel therapy for the peritoneal dissemination of gastric cancer. J Mol Med. 2009;87:385-399.
-
(2009)
J Mol Med
, vol.87
, pp. 385-399
-
-
Haley, E.S.1
Au, G.G.2
Carlton, B.R.3
-
99
-
-
42949155146
-
Potent oncolytic activity of human enteroviruses against human prostate cancer
-
Berry LJ, Au GG, Barry RD, Shafren DR. Potent oncolytic activity of human enteroviruses against human prostate cancer. Prostate. 2008; 68:577-587.
-
(2008)
Prostate
, vol.68
, pp. 577-587
-
-
Berry, L.J.1
Au, G.G.2
Barry, R.D.3
Shafren, D.R.4
-
100
-
-
17844367630
-
Oncolysis of human ovarian cancers by echovirus type 1
-
Shafren DR, Sylvester D, Johansson ES, et al. Oncolysis of human ovarian cancers by echovirus type 1. Int J Cancer. 2005;115:320-328.
-
(2005)
Int J Cancer
, vol.115
, pp. 320-328
-
-
Shafren, D.R.1
Sylvester, D.2
Johansson, E.S.3
-
101
-
-
0036652698
-
Bovine enterovirus as an oncolytic virus: Foetal calf serum facilitates its infection of human cells
-
Smyth M, Symonds A, Brazinova S, Martin J. Bovine enterovirus as an oncolytic virus: foetal calf serum facilitates its infection of human cells. Int J Mol Med. 2002;10:49-53.
-
(2002)
Int J Mol Med
, vol.10
, pp. 49-53
-
-
Smyth, M.1
Symonds, A.2
Brazinova, S.3
Martin, J.4
-
102
-
-
37549018564
-
Selective in vitro cytotoxic effect of human cancer cells by bluetongue virus-10
-
Hu J, Dong CY, Li JK, et al. Selective in vitro cytotoxic effect of human cancer cells by bluetongue virus-10. Acta Oncol. 2008;47: 124-134.
-
(2008)
Acta Oncol
, vol.47
, pp. 124-134
-
-
Hu, J.1
Dong, C.Y.2
Li, J.K.3
-
103
-
-
78650871504
-
Adenovirus-retrovirus hybrid vectors achieve highly enhanced tumor transduction and antitumor efficacy in vivo
-
Kubo S, Haga K, Tamamoto A, et al. Adenovirus-retrovirus hybrid vectors achieve highly enhanced tumor transduction and antitumor efficacy in vivo. Mol Ther. 2011;19:76-82.
-
(2011)
Mol Ther
, vol.19
, pp. 76-82
-
-
Kubo, S.1
Haga, K.2
Tamamoto, A.3
-
104
-
-
55549146090
-
Cell entry targeting restricts biodistribution of replication-competent retroviruses to tumor tissue
-
Duerner LJ, Schwantes A, Schneider IC, et al. Cell entry targeting restricts biodistribution of replication-competent retroviruses to tumor tissue. Gene Ther. 2008;15:1500-1510.
-
(2008)
Gene Ther
, vol.15
, pp. 1500-1510
-
-
Duerner, L.J.1
Schwantes, A.2
Schneider, I.C.3
-
105
-
-
27744482203
-
Experimental therapy of allogeneic solid tumors induced in athymic mice with suicide genetransducing replication-competent foamy virus vectors
-
Heinkelein M, Hoffmann U, Lucke M, et al. Experimental therapy of allogeneic solid tumors induced in athymic mice with suicide genetransducing replication-competent foamy virus vectors. Cancer Gene Ther. 2005;12:947-953.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 947-953
-
-
Heinkelein, M.1
Hoffmann, U.2
Lucke, M.3
-
106
-
-
79954510865
-
Current good manufacturing practice production of an oncolytic recombinant vesicular stomatitis viral vector for cancer treatment
-
Ausubel LJ, Meseck M, Derecho I, et al. Current good manufacturing practice production of an oncolytic recombinant vesicular stomatitis viral vector for cancer treatment. Hum Gene Ther. 2011;22: 489-497.
-
(2011)
Hum Gene Ther
, vol.22
, pp. 489-497
-
-
Ausubel, L.J.1
Meseck, M.2
Derecho, I.3
-
107
-
-
77955177289
-
Identification of genetically modified Maraba virus as an oncolytic rhabdovirus
-
Brun J, McManus D, Lefebvre C, et al. Identification of genetically modified Maraba virus as an oncolytic rhabdovirus. Mol Ther. 2010;18:1440-1449.
-
(2010)
Mol Ther
, vol.18
, pp. 1440-1449
-
-
Brun, J.1
McManus, D.2
Lefebvre, C.3
-
108
-
-
77950518121
-
Enhancing the therapeutic effect against ovarian cancer through a combination of viral oncolysis and antigen-specific immunotherapy
-
Zhang YQ, Tsai YC, Monie A, et al. Enhancing the therapeutic effect against ovarian cancer through a combination of viral oncolysis and antigen-specific immunotherapy. Mol Ther. 2010;18:692-699.
-
(2010)
Mol Ther
, vol.18
, pp. 692-699
-
-
Zhang, Y.Q.1
Tsai, Y.C.2
Monie, A.3
-
110
-
-
77949654870
-
Enhanced specific delivery and targeting of oncolytic Sindbis viral vectors by modulating vascular leakiness in tumor
-
Tseng JC, Granot T, Digiacomo V, et al. Enhanced specific delivery and targeting of oncolytic Sindbis viral vectors by modulating vascular leakiness in tumor. Cancer Gene Ther. 2010;17:244-255.
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 244-255
-
-
Tseng, J.C.1
Granot, T.2
Digiacomo, V.3
-
111
-
-
20444461981
-
Oncolytic viral therapy for cervical and ovarian cancer cells by Sindbis virus AR339 strain
-
Unno Y, Shino Y, Kondo F, et al. Oncolytic viral therapy for cervical and ovarian cancer cells by Sindbis virus AR339 strain. Clin Cancer Res. 2005;11:4553-4560.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4553-4560
-
-
Unno, Y.1
Shino, Y.2
Kondo, F.3
-
112
-
-
21244504240
-
The 67 kDa laminin receptor increases tumor aggressiveness by remodeling laminin-1
-
Berno V, Porrini D, Castiglioni F, et al. The 67 kDa laminin receptor increases tumor aggressiveness by remodeling laminin-1. Endocr Relat Cancer. 2005;12:393-406.
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 393-406
-
-
Berno, V.1
Porrini, D.2
Castiglioni, F.3
-
113
-
-
0026628752
-
High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells
-
Wang KS, Kuhn RJ, Strauss EG, et al. High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J Virol. 1992;66: 4992-5001.
-
(1992)
J Virol
, vol.66
, pp. 4992-5001
-
-
Wang, K.S.1
Kuhn, R.J.2
Strauss, E.G.3
-
114
-
-
1642453768
-
Systemic therapy of malignant human melanoma tumors by a common cold-producing enterovirus, coxsackievirus a21
-
Shafren DR, Au GG, Nguyen T, et al. Systemic therapy of malignant human melanoma tumors by a common cold-producing enterovirus, coxsackievirus a21. Clin Cancer Res. 2004;10:53-60.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 53-60
-
-
Shafren, D.R.1
Au, G.G.2
Nguyen, T.3
-
115
-
-
68949163770
-
Human cancer cells have specifically lost the ability to induce the synergistic state caused by tumor necrosis factor plus interferon-beta
-
Bartee E, McFadden G. Human cancer cells have specifically lost the ability to induce the synergistic state caused by tumor necrosis factor plus interferon-beta. Cytokine. 2009;47:199-205.
-
(2009)
Cytokine
, vol.47
, pp. 199-205
-
-
Bartee, E.1
McFadden, G.2
-
116
-
-
34547097764
-
The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: Implication for the defective interferon response in cancer cells
-
Noser JA, Mael AA, Sakuma R, et al. The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: implication for the defective interferon response in cancer cells. Mol Ther. 2007;15: 1531-1536.
-
(2007)
Mol Ther
, vol.15
, pp. 1531-1536
-
-
Noser, J.A.1
Mael, A.A.2
Sakuma, R.3
-
118
-
-
79958119977
-
Oncolytic specificity of Newcastle disease virus is mediated by selectivity for apoptosis-resistant cells
-
Mansour M, Palese P, Zamarin D. Oncolytic specificity of Newcastle disease virus is mediated by selectivity for apoptosis-resistant cells. J Virol. 2011;85:6015-6023.
-
(2011)
J Virol
, vol.85
, pp. 6015-6023
-
-
Mansour, M.1
Palese, P.2
Zamarin, D.3
-
120
-
-
34748903753
-
Myxoma virus and oncolytic virotherapy: A new biologic weapon in the war against cancer
-
Stanford MM, McFadden G. Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer. Expert Opin Biol Ther. 2007;7:1415-1425.
-
(2007)
Expert Opin Biol Ther
, vol.7
, pp. 1415-1425
-
-
Stanford, M.M.1
McFadden, G.2
-
121
-
-
37849032052
-
Herpes simplex virus type 1 preferentially targets human colon carcinoma: Role of extracellular matrix
-
Kolodkin-Gal D, Zamir G, Edden Y, et al. Herpes simplex virus type 1 preferentially targets human colon carcinoma: role of extracellular matrix. J Virol. 2008;82:999-1010.
-
(2008)
J Virol
, vol.82
, pp. 999-1010
-
-
Kolodkin-Gal, D.1
Zamir, G.2
Edden, Y.3
-
122
-
-
67449093868
-
In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery
-
Coughlan L, Vallath S, Saha A, et al. In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery. J Virol. 2009; 83:6416-6428.
-
(2009)
J Virol
, vol.83
, pp. 6416-6428
-
-
Coughlan, L.1
Vallath, S.2
Saha, A.3
-
123
-
-
77955925502
-
Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells
-
Grandi P, Fernandez J, Szentirmai O, et al. Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells. Cancer Gene Ther. 2010;17:655-663.
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 655-663
-
-
Grandi, P.1
Fernandez, J.2
Szentirmai, O.3
-
124
-
-
67049100254
-
Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells
-
Menotti L, Nicoletti G, Gatta V, et al. Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells. Proc Natl Acad Sci U S A. 2009; 106:9039-9044.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9039-9044
-
-
Menotti, L.1
Nicoletti, G.2
Gatta, V.3
-
125
-
-
67449152194
-
Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer
-
Liu C, Hasegawa K, Russell SJ, et al. Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer. Prostate. 2009;69:1128-1141.
-
(2009)
Prostate
, vol.69
, pp. 1128-1141
-
-
Liu, C.1
Hasegawa, K.2
Russell, S.J.3
-
126
-
-
60549116916
-
Tumor and vascular targeting of a novel oncolytic measles virus retargeted against the urokinase receptor
-
Jing Y, Tong C, Zhang J, et al. Tumor and vascular targeting of a novel oncolytic measles virus retargeted against the urokinase receptor. Cancer Res. 2009;69:1459-1468.
-
(2009)
Cancer Res
, vol.69
, pp. 1459-1468
-
-
Jing, Y.1
Tong, C.2
Zhang, J.3
-
127
-
-
33750700474
-
The use of a tropismmodified measles virus in folate receptor-targeted virotherapy of ovarian cancer
-
Hasegawa K, Nakamura T, Harvey M, et al. The use of a tropismmodified measles virus in folate receptor-targeted virotherapy of ovarian cancer. Clin Cancer Res. 2006;12:6170-6178.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6170-6178
-
-
Hasegawa, K.1
Nakamura, T.2
Harvey, M.3
-
128
-
-
13844254649
-
Rescue and propagation of fully retargeted oncolytic measles viruses
-
Nakamura T, Peng KW, Harvey M, et al. Rescue and propagation of fully retargeted oncolytic measles viruses. Nat Biotechnol. 2005;23:209-214.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 209-214
-
-
Nakamura, T.1
Peng, K.W.2
Harvey, M.3
-
129
-
-
33646746200
-
A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors
-
Menotti L, Cerretani A, Campadelli-Fiume G. A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors. J Virol. 2006;80:5531-5539.
-
(2006)
J Virol
, vol.80
, pp. 5531-5539
-
-
Menotti, L.1
Cerretani, A.2
Campadelli-Fiume, G.3
-
130
-
-
62549133989
-
Generation of optimized and urokinase-targeted oncolytic Sendai virus vectors applicable for various human malignancies
-
Kinoh H, Inoue M, Komaru A, et al. Generation of optimized and urokinase-targeted oncolytic Sendai virus vectors applicable for various human malignancies. Gene Ther. 2009;16:392-403.
-
(2009)
Gene Ther
, vol.16
, pp. 392-403
-
-
Kinoh, H.1
Inoue, M.2
Komaru, A.3
-
131
-
-
33747871572
-
Oncolytic efficacy and enhanced safety of measles virus activated by tumor-secreted matrix metalloproteinases
-
Springfeld C, von Messling V, Frenzke M, et al. Oncolytic efficacy and enhanced safety of measles virus activated by tumor-secreted matrix metalloproteinases. Cancer Res. 2006;66:7694-7700.
-
(2006)
Cancer Res
, vol.66
, pp. 7694-7700
-
-
Springfeld, C.1
von Messling, V.2
Frenzke, M.3
-
132
-
-
63849225752
-
Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
-
Wakimoto H, Kesari S, Farrell CJ, et al. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 2009;69:3472-3481.
-
(2009)
Cancer Res
, vol.69
, pp. 3472-3481
-
-
Wakimoto, H.1
Kesari, S.2
Farrell, C.J.3
-
133
-
-
0036212495
-
Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5
-
Nakamura H, Kasuya H, Mullen JT, et al. Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5. J Clin Invest. 2002;109:871-882.
-
(2002)
J Clin Invest
, vol.109
, pp. 871-882
-
-
Nakamura, H.1
Kasuya, H.2
Mullen, J.T.3
-
134
-
-
58349108062
-
E1A, E1B double-restricted replicative adenovirus at low dose greatly augments tumor-specific suicide gene therapy for gallbladder cancer
-
Fukuda K, Abei M, Ugai H, et al. E1A, E1B double-restricted replicative adenovirus at low dose greatly augments tumor-specific suicide gene therapy for gallbladder cancer. Cancer Gene Ther. 2009;16: 126-136.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 126-136
-
-
Fukuda, K.1
Abei, M.2
Ugai, H.3
-
135
-
-
0041589480
-
E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer
-
Fukuda K, Abei M, Ugai H, et al. E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer. Cancer Res. 2003;63:4434-4440.
-
(2003)
Cancer Res
, vol.63
, pp. 4434-4440
-
-
Fukuda, K.1
Abei, M.2
Ugai, H.3
-
136
-
-
36049009021
-
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963
-
Thorne SH, Hwang TH, O'Gorman WE, et al. Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963. J Clin Invest. 2007;117: 3350-3358.
-
(2007)
J Clin Invest
, vol.117
, pp. 3350-3358
-
-
Thorne, S.H.1
Hwang, T.H.2
O'Gorman, W.E.3
-
137
-
-
79951725000
-
Dual E1A oncolytic adenovirus: Targeting tumor heterogeneity with two independent cancer-specific promoter elements, DF3/MUC1 and hTERT
-
Doloff JC, Jounaidi Y, Waxman DJ. Dual E1A oncolytic adenovirus: targeting tumor heterogeneity with two independent cancer-specific promoter elements, DF3/MUC1 and hTERT. Cancer Gene Ther. 2011; 18:153-166.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 153-166
-
-
Doloff, J.C.1
Jounaidi, Y.2
Waxman, D.J.3
-
138
-
-
77952009074
-
Transcriptional and translational dual-regulated oncolytic herpes simplex virus type 1 for targeting prostate tumors
-
Lee CY, Bu LX, DeBenedetti A, et al. Transcriptional and translational dual-regulated oncolytic herpes simplex virus type 1 for targeting prostate tumors. Mol Ther. 2010;18:929-935.
-
(2010)
Mol Ther
, vol.18
, pp. 929-935
-
-
Lee, C.Y.1
Bu, L.X.2
Debenedetti, A.3
-
139
-
-
68949202259
-
Potent antitumor effect of interleukin-24 gene in the survivin promoter and retinoblastoma double-regulated oncolytic adenovirus
-
Zhang KJ, Wang YG, Cao X, et al. Potent antitumor effect of interleukin-24 gene in the survivin promoter and retinoblastoma double-regulated oncolytic adenovirus. Hum Gene Ther. 2009;20: 818-830.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 818-830
-
-
Zhang, K.J.1
Wang, Y.G.2
Cao, X.3
-
141
-
-
77954585191
-
Carrier cell-mediated cell lysis of squamous cell carcinoma cells by squamous cell carcinoma antigen 1 promoter-driven oncolytic adenovirus
-
Hamada K, Zhang T, Desaki J, et al. Carrier cell-mediated cell lysis of squamous cell carcinoma cells by squamous cell carcinoma antigen 1 promoter-driven oncolytic adenovirus. J Gene Med. 2010;12:545-554.
-
(2010)
J Gene Med
, vol.12
, pp. 545-554
-
-
Hamada, K.1
Zhang, T.2
Desaki, J.3
-
142
-
-
79957910157
-
MicroRNA regulation of glycoprotein B5R in oncolytic vaccinia virus reduces viral pathogenicity without impairing its antitumor efficacy
-
Hikichi M, Kidokoro M, Haraguchi T, et al. MicroRNA regulation of glycoprotein B5R in oncolytic vaccinia virus reduces viral pathogenicity without impairing its antitumor efficacy. Mol Ther. 2011; 19:1107-1115.
-
(2011)
Mol Ther
, vol.19
, pp. 1107-1115
-
-
Hikichi, M.1
Kidokoro, M.2
Haraguchi, T.3
-
143
-
-
55549100223
-
Engineering microRNA responsiveness to decrease virus pathogenicity
-
Kelly EJ, Hadac EM, Greiner S, Russell SJ. Engineering microRNA responsiveness to decrease virus pathogenicity. Nat Med. 2008;14: 1278-1283.
-
(2008)
Nat Med
, vol.14
, pp. 1278-1283
-
-
Kelly, E.J.1
Hadac, E.M.2
Greiner, S.3
Russell, S.J.4
-
144
-
-
55549108699
-
Generation of a conditionally replicating adenovirus based on targeted destruction of E1A mRNA by a cell type-specific MicroRNA
-
Ylosmaki E, Hakkarainen T, Hemminki A, et al. Generation of a conditionally replicating adenovirus based on targeted destruction of E1A mRNA by a cell type-specific MicroRNA. J Virol. 2008;82: 11009-11015.
-
(2008)
J Virol
, vol.82
, pp. 11009-11015
-
-
Ylosmaki, E.1
Hakkarainen, T.2
Hemminki, A.3
-
145
-
-
48349145992
-
A let-7 microRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication
-
Edge RE, Falls TJ, Brown CW, et al. A let-7 microRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication. Mol Ther. 2008;16:1437-1443.
-
(2008)
Mol Ther
, vol.16
, pp. 1437-1443
-
-
Edge, R.E.1
Falls, T.J.2
Brown, C.W.3
-
146
-
-
0034653696
-
Fusogenic membrane glycoproteins as a novel class of genes for the local and immune-mediated control of tumor growth
-
Bateman A, Bullough F, Murphy S, et al. Fusogenic membrane glycoproteins as a novel class of genes for the local and immune-mediated control of tumor growth. Cancer Res. 2000;60:1492-1497.
-
(2000)
Cancer Res
, vol.60
, pp. 1492-1497
-
-
Bateman, A.1
Bullough, F.2
Murphy, S.3
-
147
-
-
0034077666
-
Replication-selective adenoviruses as oncolytic agents
-
Heise C, Kirn DH. Replication-selective adenoviruses as oncolytic agents. J Clin Invest. 2000;105:847-851.
-
(2000)
J Clin Invest
, vol.105
, pp. 847-851
-
-
Heise, C.1
Kirn, D.H.2
-
148
-
-
34748880650
-
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: Role of autophagic cell death
-
Jiang H, Gomez-Manzano C, Aoki H, et al. Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death. J Natl Cancer Inst. 2007;99:1410-1414.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1410-1414
-
-
Jiang, H.1
Gomez-Manzano, C.2
Aoki, H.3
-
149
-
-
83655192074
-
Potentiation of tumor radiotherapy by a radiation-inducible oncolytic and oncoapoptotic adenovirus in cervical cancer xenografts
-
Wang H, Song X, Zhang H, et al. Potentiation of tumor radiotherapy by a radiation-inducible oncolytic and oncoapoptotic adenovirus in cervical cancer xenografts. Int J Cancer. 2012;130:443-453.
-
(2012)
Int J Cancer
, vol.130
, pp. 443-453
-
-
Wang, H.1
Song, X.2
Zhang, H.3
-
150
-
-
69549126167
-
Concomitant use of Ad5/35 chimeric oncolytic adenovirus with TRAIL gene and taxol produces synergistic cytotoxicity in gastric cancer cells
-
Chen L, Chen D, Gong M, et al. Concomitant use of Ad5/35 chimeric oncolytic adenovirus with TRAIL gene and taxol produces synergistic cytotoxicity in gastric cancer cells. Cancer Lett. 2009;284: 141-148.
-
(2009)
Cancer Lett
, vol.284
, pp. 141-148
-
-
Chen, L.1
Chen, D.2
Gong, M.3
-
151
-
-
34548810924
-
A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models
-
Wohlfahrt ME, Beard BC, Lieber A, Kiem HP. A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models. Cancer Res. 2007;67:8783-8790.
-
(2007)
Cancer Res
, vol.67
, pp. 8783-8790
-
-
Wohlfahrt, M.E.1
Beard, B.C.2
Lieber, A.3
Kiem, H.P.4
-
152
-
-
33749864535
-
The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer
-
Zhao L, Dong A, Gu J, et al. The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer. Cancer Gene Ther. 2006;13:1011-1022.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 1011-1022
-
-
Zhao, L.1
Dong, A.2
Gu, J.3
-
153
-
-
2342637176
-
Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer
-
Ebert O, Shinozaki K, Kournioti C, et al. Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer. Cancer Res. 2004;64:3265-3270.
-
(2004)
Cancer Res
, vol.64
, pp. 3265-3270
-
-
Ebert, O.1
Shinozaki, K.2
Kournioti, C.3
-
154
-
-
0036830143
-
Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency
-
van Beusechem VW, van den Doel PB, Grill J, et al. Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency. Cancer Res. 2002;62:6165-6171.
-
(2002)
Cancer Res
, vol.62
, pp. 6165-6171
-
-
van Beusechem, V.W.1
van den Doel, P.B.2
Grill, J.3
-
155
-
-
67349239664
-
E2F promoter-regulated oncolytic adenovirus with p16 gene induces cell apoptosis and exerts antitumor effect on gastric cancer
-
Ma J, He X, Wang W, et al. E2F promoter-regulated oncolytic adenovirus with p16 gene induces cell apoptosis and exerts antitumor effect on gastric cancer. Dig Dis Sci. 2009;54:1425-1431.
-
(2009)
Dig Dis Sci
, vol.54
, pp. 1425-1431
-
-
Ma, J.1
He, X.2
Wang, W.3
-
156
-
-
38649136288
-
Transfer of suppressor of cytokine signaling 3 by an oncolytic adenovirus induces potential antitumor activities in hepatocellular carcinoma
-
Cui Q, Jiang W, Wang Y, et al. Transfer of suppressor of cytokine signaling 3 by an oncolytic adenovirus induces potential antitumor activities in hepatocellular carcinoma. Hepatology. 2008;47: 105-112.
-
(2008)
Hepatology
, vol.47
, pp. 105-112
-
-
Cui, Q.1
Jiang, W.2
Wang, Y.3
-
157
-
-
83555170821
-
A new oncolytic adenoviral vector carrying dual tumor suppressor genes shows potent antitumor effect
-
July 27, Epub ahead of print
-
Liu XR, Cai Y, Cao X, et al. A new oncolytic adenoviral vector carrying dual tumor suppressor genes shows potent antitumor effect. J Cell Mol Med. July 27, 2011. [Epub ahead of print.].
-
(2011)
J Cell Mol Med
-
-
Liu, X.R.1
Cai, Y.2
Cao, X.3
-
158
-
-
66149135973
-
Inhibition of renal cancer cell growth by oncolytic adenovirus armed short hairpin RNA targeting hTERT gene
-
Zheng JN, Pei DS, Sun FH, et al. Inhibition of renal cancer cell growth by oncolytic adenovirus armed short hairpin RNA targeting hTERT gene. Cancer Biol Ther. 2009;8:84-91.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 84-91
-
-
Zheng, J.N.1
Pei, D.S.2
Sun, F.H.3
-
159
-
-
57649135364
-
Inhibition of renal cancer cell growth in vitro and in vivo with oncolytic adenovirus armed short hairpin RNA targeting Ki-67 encoding mRNA
-
Zheng JN, Pei DS, Mao LJ, et al. Inhibition of renal cancer cell growth in vitro and in vivo with oncolytic adenovirus armed short hairpin RNA targeting Ki-67 encoding mRNA. Cancer Gene Ther. 2009;16:20-32.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 20-32
-
-
Zheng, J.N.1
Pei, D.S.2
Mao, L.J.3
-
160
-
-
68149160020
-
Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo
-
Shen W, Wang CY, Wang XH, Fu ZX. Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo. J Exp Clin Cancer Res. 2009;28:81.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 81
-
-
Shen, W.1
Wang, C.Y.2
Wang, X.H.3
Fu, Z.X.4
-
161
-
-
40949151900
-
Oncolytic adenovirus-mediated shRNA against Apollon inhibits tumor cell growth and enhances antitumor effect of 5-fluorouracil
-
Chu L, Gu J, Sun L, et al. Oncolytic adenovirus-mediated shRNA against Apollon inhibits tumor cell growth and enhances antitumor effect of 5-fluorouracil. Gene Ther. 2008;15:484-494.
-
(2008)
Gene Ther
, vol.15
, pp. 484-494
-
-
Chu, L.1
Gu, J.2
Sun, L.3
-
162
-
-
79955619094
-
Targeting tumor vasculature with an oncolytic virus
-
Breitbach CJ, De Silva NS, Falls TJ, et al. Targeting tumor vasculature with an oncolytic virus. Mol Ther. 2011;19:886-894.
-
(2011)
Mol Ther
, vol.19
, pp. 886-894
-
-
Breitbach, C.J.1
de Silva, N.S.2
Falls, T.J.3
-
163
-
-
50549091297
-
The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinoma
-
Liu TC, Hwang T, Park BH, et al. The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinoma. Mol Ther. 2008;16: 1637-1642.
-
(2008)
Mol Ther
, vol.16
, pp. 1637-1642
-
-
Liu, T.C.1
Hwang, T.2
Park, B.H.3
-
164
-
-
57649118854
-
Enhanced combined tumor-specific oncolysis and suicide gene therapy for prostate cancer using M6 promoter
-
Ahn M, Lee SJ, Li X, et al. Enhanced combined tumor-specific oncolysis and suicide gene therapy for prostate cancer using M6 promoter. Cancer Gene Ther. 2009;16:73-82.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 73-82
-
-
Ahn, M.1
Lee, S.J.2
Li, X.3
-
165
-
-
66749163693
-
Combination effect of oncolytic adenovirus therapy and herpes simplex virus thymidine kinase/ganciclovir in hepatic carcinoma animal models
-
Zheng FQ, Xu Y, Yang RJ, et al. Combination effect of oncolytic adenovirus therapy and herpes simplex virus thymidine kinase/ganciclovir in hepatic carcinoma animal models. Acta Pharmacol Sin. 2009;30:617-627.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 617-627
-
-
Zheng, F.Q.1
Xu, Y.2
Yang, R.J.3
-
166
-
-
79960557570
-
Armed and targeted measles virus for chemovirotherapy of pancreatic cancer
-
Bossow S, Grossardt C, Temme A, et al. Armed and targeted measles virus for chemovirotherapy of pancreatic cancer. Cancer Gene Ther. 2011;18:598-608.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 598-608
-
-
Bossow, S.1
Grossardt, C.2
Temme, A.3
-
167
-
-
38349079989
-
Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene
-
Chalikonda S, Kivlen MH, O'Malley ME, et al. Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene. Cancer Gene Ther. 2008; 15:115-125.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 115-125
-
-
Chalikonda, S.1
Kivlen, M.H.2
O'Malley, M.E.3
-
168
-
-
53649094575
-
Targeted delivery of a suicide gene to human colorectal tumors by a conditionally replicating vaccinia virus
-
Foloppe J, Kintz J, Futin N, et al. Targeted delivery of a suicide gene to human colorectal tumors by a conditionally replicating vaccinia virus. Gene Ther. 2008;15:1361-1371.
-
(2008)
Gene Ther
, vol.15
, pp. 1361-1371
-
-
Foloppe, J.1
Kintz, J.2
Futin, N.3
-
169
-
-
67650889118
-
Antitumor activity of a selectively replication competent herpes simplex virus (HSV) with enzyme prodrug therapy
-
Braidwood L, Dunn PD, Hardy S, et al. Antitumor activity of a selectively replication competent herpes simplex virus (HSV) with enzyme prodrug therapy. Anticancer Res. 2009;29:2159-2166.
-
(2009)
Anticancer Res
, vol.29
, pp. 2159-2166
-
-
Braidwood, L.1
Dunn, P.D.2
Hardy, S.3
-
170
-
-
69949092199
-
Targeted radiotherapy for prostate cancer with an oncolytic adenovirus coding for human sodium iodide symporter
-
Hakkarainen T, Rajecki M, Sarparanta M, et al. Targeted radiotherapy for prostate cancer with an oncolytic adenovirus coding for human sodium iodide symporter. Clin Cancer Res. 2009;15:5396-5403.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5396-5403
-
-
Hakkarainen, T.1
Rajecki, M.2
Sarparanta, M.3
-
171
-
-
34948830701
-
Radioiodide imaging and radiovirotherapy of multiple myeloma using VSV (Delta51)-NIS, an attenuated vesicular stomatitis virus encoding the sodium iodide symporter gene
-
Goel A, Carlson SK, Classic KL, et al. Radioiodide imaging and radiovirotherapy of multiple myeloma using VSV (Delta51)-NIS, an attenuated vesicular stomatitis virus encoding the sodium iodide symporter gene. Blood. 2007;110:2342-2350.
-
(2007)
Blood
, vol.110
, pp. 2342-2350
-
-
Goel, A.1
Carlson, S.K.2
Classic, K.L.3
-
172
-
-
77954814628
-
Oncolytic measles viruses encoding interferon beta and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy
-
Li H, Peng KW, Dingli D, et al. Oncolytic measles viruses encoding interferon beta and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy. Cancer Gene Ther. 2010;17: 550-558.
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 550-558
-
-
Li, H.1
Peng, K.W.2
Dingli, D.3
-
173
-
-
33845674583
-
Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma
-
Blechacz B, Splinter PL, Greiner S, et al. Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma. Hepatology. 2006;44:1465-1477.
-
(2006)
Hepatology
, vol.44
, pp. 1465-1477
-
-
Blechacz, B.1
Splinter, P.L.2
Greiner, S.3
-
174
-
-
33645663329
-
Dual therapy of ovarian cancer using measles viruses expressing carcinoembryonic antigen and sodium iodide symporter
-
Hasegawa K, Pham L, O'Connor MK, et al. Dual therapy of ovarian cancer using measles viruses expressing carcinoembryonic antigen and sodium iodide symporter. Clin Cancer Res. 2006;12:1868-1875.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1868-1875
-
-
Hasegawa, K.1
Pham, L.2
O'Connor, M.K.3
-
175
-
-
1442356959
-
Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter
-
Dingli D, Peng KW, Harvey ME, et al. Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter. Blood. 2004;103:1641-1646.
-
(2004)
Blood
, vol.103
, pp. 1641-1646
-
-
Dingli, D.1
Peng, K.W.2
Harvey, M.E.3
-
176
-
-
26844494479
-
HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer
-
Benencia F, Courreges MC, Conejo-Garcia JR, et al. HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer. Mol Ther. 2005;12: 789-802.
-
(2005)
Mol Ther
, vol.12
, pp. 789-802
-
-
Benencia, F.1
Courreges, M.C.2
Conejo-Garcia, J.R.3
-
177
-
-
42049104455
-
Virus-mediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation
-
Endo Y, Sakai R, Ouchi M, et al. Virus-mediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation. Oncogene. 2008;27: 2375-2381.
-
(2008)
Oncogene
, vol.27
, pp. 2375-2381
-
-
Endo, Y.1
Sakai, R.2
Ouchi, M.3
-
178
-
-
44449091136
-
Reovirus activates human dendritic cells to promote innate antitumor immunity
-
Errington F, Steele L, Prestwich R, et al. Reovirus activates human dendritic cells to promote innate antitumor immunity. J Immunol. 2008; 180:6018-6026.
-
(2008)
J Immunol
, vol.180
, pp. 6018-6026
-
-
Errington, F.1
Steele, L.2
Prestwich, R.3
-
179
-
-
79952361112
-
Pro-inflammatory cytokine/ chemokine production by reovirus treated melanoma cells is PKR/ NF-kappaB mediated and supports innate and adaptive anti-tumor immune priming
-
Steele L, Errington F, Prestwich R, et al. Pro-inflammatory cytokine/ chemokine production by reovirus treated melanoma cells is PKR/ NF-kappaB mediated and supports innate and adaptive anti-tumor immune priming. Mol Cancer. 2011;10:20.
-
(2011)
Mol Cancer
, vol.10
, pp. 20
-
-
Steele, L.1
Errington, F.2
Prestwich, R.3
-
180
-
-
78649661117
-
Reovirus virotherapy overrides tumor antigen presentation evasion and promotes protective antitumor immunity
-
Gujar SA, Marcato P, Pan D, Lee PW. Reovirus virotherapy overrides tumor antigen presentation evasion and promotes protective antitumor immunity. Mol Cancer Ther. 2010;9:2924-2933.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2924-2933
-
-
Gujar, S.A.1
Marcato, P.2
Pan, D.3
Lee, P.W.4
-
181
-
-
51049090205
-
Inflammatory tumor cell killing by oncolytic reovirus for the treatment of melanoma
-
Errington F, White CL, Twigger KR, et al. Inflammatory tumor cell killing by oncolytic reovirus for the treatment of melanoma. Gene Ther. 2008;15:1257-1270.
-
(2008)
Gene Ther
, vol.15
, pp. 1257-1270
-
-
Errington, F.1
White, C.L.2
Twigger, K.R.3
-
182
-
-
62449131194
-
Immunogenic cell death modalities and their impact on cancer treatment
-
Kepp O, Tesniere A, Schlemmer F, et al. Immunogenic cell death modalities and their impact on cancer treatment. Apoptosis. 2009;14:364-375.
-
(2009)
Apoptosis
, vol.14
, pp. 364-375
-
-
Kepp, O.1
Tesniere, A.2
Schlemmer, F.3
-
184
-
-
79951508366
-
Synergistic anti-tumor effects between oncolytic vaccinia virus and paclitaxel are mediated by the IFN response and HMGB1
-
Huang B, Sikorski R, Kirn DH, Thorne SH. Synergistic anti-tumor effects between oncolytic vaccinia virus and paclitaxel are mediated by the IFN response and HMGB1. Gene Ther. 2011;18:164-172.
-
(2011)
Gene Ther
, vol.18
, pp. 164-172
-
-
Huang, B.1
Sikorski, R.2
Kirn, D.H.3
Thorne, S.H.4
-
185
-
-
49649111732
-
Measles virus induces oncolysis of mesothelioma cells and allows dendritic cells to cross-prime tumor-specific CD8 response
-
Gauvrit A, Brandler S, Sapede-Peroz C, et al. Measles virus induces oncolysis of mesothelioma cells and allows dendritic cells to cross-prime tumor-specific CD8 response. Cancer Res. 2008;68: 4882-4892.
-
(2008)
Cancer Res
, vol.68
, pp. 4882-4892
-
-
Gauvrit, A.1
Brandler, S.2
Sapede-Peroz, C.3
-
186
-
-
27544491235
-
The enhanced tumor selectivity of an oncolytic vaccinia lacking the host range and antiapoptosis genes SPI-1 and SPI-2
-
Guo ZS, Naik A, O'Malley ME, et al. The enhanced tumor selectivity of an oncolytic vaccinia lacking the host range and antiapoptosis genes SPI-1 and SPI-2. Cancer Res. 2005;65:9991-9998.
-
(2005)
Cancer Res
, vol.65
, pp. 9991-9998
-
-
Guo, Z.S.1
Naik, A.2
O'Malley, M.E.3
-
187
-
-
0036780171
-
Dendritic cells pulsed with viral oncolysates potently stimulate autologous T cells from cancer patients
-
Bai L, Koopmann J, Fiola C, et al. Dendritic cells pulsed with viral oncolysates potently stimulate autologous T cells from cancer patients. Int J Oncol. 2002;21:685-694.
-
(2002)
Int J Oncol
, vol.21
, pp. 685-694
-
-
Bai, L.1
Koopmann, J.2
Fiola, C.3
-
188
-
-
84855968515
-
Potentiating cancer immunotherapy using an oncolytic virus
-
Bridle BW, Stephenson KB, Boudreau JE, et al. Potentiating cancer immunotherapy using an oncolytic virus. Mol Ther. 2010;184: 4269-4275.
-
(2010)
Mol Ther
, vol.184
, pp. 4269-4275
-
-
Bridle, B.W.1
Stephenson, K.B.2
Boudreau, J.E.3
-
189
-
-
34548574975
-
Phagocytosis and antigen presentation in dendritic cells
-
Savina A, Amigorena S. Phagocytosis and antigen presentation in dendritic cells. Immunol Rev. 2007;219:143-156.
-
(2007)
Immunol Rev
, vol.219
, pp. 143-156
-
-
Savina, A.1
Amigorena, S.2
-
190
-
-
0033592902
-
Extracellular antigen processing and presentation by immature dendritic cells
-
Santambrogio L, Sato AK, Carven GJ, et al. Extracellular antigen processing and presentation by immature dendritic cells. Proc Natl Acad Sci U S A. 1999;96:15056-15061.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 15056-15061
-
-
Santambrogio, L.1
Sato, A.K.2
Carven, G.J.3
-
191
-
-
70449698537
-
Reciprocal human dendritic cell-natural killer cell interactions induce antitumor activity following tumor cell infection by oncolytic reovirus
-
Prestwich RJ, Errington F, Steele LP, et al. Reciprocal human dendritic cell-natural killer cell interactions induce antitumor activity following tumor cell infection by oncolytic reovirus. J Immunol. 2009;183: 4312-4321.
-
(2009)
J Immunol
, vol.183
, pp. 4312-4321
-
-
Prestwich, R.J.1
Errington, F.2
Steele, L.P.3
-
192
-
-
44849140982
-
Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial
-
White CL, Twigger KR, Vidal L, et al. Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial. Gene Ther. 2008;15:911-920.
-
(2008)
Gene Ther
, vol.15
, pp. 911-920
-
-
White, C.L.1
Twigger, K.R.2
Vidal, L.3
-
193
-
-
58149359320
-
Tumor infection by oncolytic reovirus primes adaptive antitumor immunity
-
Prestwich RJ, Errington F, Ilett EJ, et al. Tumor infection by oncolytic reovirus primes adaptive antitumor immunity. Clin Cancer Res. 2008;14:7358-7366.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7358-7366
-
-
Prestwich, R.J.1
Errington, F.2
Ilett, E.J.3
-
194
-
-
79551614963
-
Adaptive antiviral immunity is a determinant of the therapeutic success of oncolytic virotherapy
-
Sobol PT, Boudreau JE, Stephenson K, et al. Adaptive antiviral immunity is a determinant of the therapeutic success of oncolytic virotherapy. Mol Ther. 2011;19:335-344.
-
(2011)
Mol Ther
, vol.19
, pp. 335-344
-
-
Sobol, P.T.1
Boudreau, J.E.2
Stephenson, K.3
-
195
-
-
34047177961
-
Induction of strong antitumor immunity by an HSV-2-based oncolytic virus in a murine mammary tumor model
-
Li H, Dutuor A, Fu X, Zhang X. Induction of strong antitumor immunity by an HSV-2-based oncolytic virus in a murine mammary tumor model. J Gene Med. 2007;9:161-169.
-
(2007)
J Gene Med
, vol.9
, pp. 161-169
-
-
Li, H.1
Dutuor, A.2
Fu, X.3
Zhang, X.4
-
196
-
-
28444480639
-
The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma
-
Hummel JL, Safroneeva E, Mossman KL. The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma. Mol Ther. 2005;12:1101-1110.
-
(2005)
Mol Ther
, vol.12
, pp. 1101-1110
-
-
Hummel, J.L.1
Safroneeva, E.2
Mossman, K.L.3
-
197
-
-
2442661484
-
Destruction of nonimmunogenic mammary tumor cells by a fusogenic oncolytic herpes simplex virus induces potent antitumor immunity
-
Nakamori M, Fu X, Rousseau R, et al. Destruction of nonimmunogenic mammary tumor cells by a fusogenic oncolytic herpes simplex virus induces potent antitumor immunity. Mol Ther. 2004;9:658-665.
-
(2004)
Mol Ther
, vol.9
, pp. 658-665
-
-
Nakamori, M.1
Fu, X.2
Rousseau, R.3
-
198
-
-
0036215782
-
Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV
-
Toda M, Iizuka Y, Kawase T, et al. Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV. Cancer Gene Ther. 2002;9:356-364.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 356-364
-
-
Toda, M.1
Iizuka, Y.2
Kawase, T.3
-
199
-
-
23844451373
-
Parvovirus H-1-induced tumor cell death enhances human immune response in vitro via increased phagocytosis, maturation, and cross-presentation by dendritic cells
-
Moehler MH, Zeidler M, Wilsberg V, et al. Parvovirus H-1-induced tumor cell death enhances human immune response in vitro via increased phagocytosis, maturation, and cross-presentation by dendritic cells. Hum Gene Ther. 2005;16:996-1005.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 996-1005
-
-
Moehler, M.H.1
Zeidler, M.2
Wilsberg, V.3
-
200
-
-
78650609261
-
Enhancement of NK cell anti-tumor responses using an oncolytic parvovirus
-
Bhat R, Dempe S, Dinsart C, Rommelaere J. Enhancement of NK cell anti-tumor responses using an oncolytic parvovirus. Int J Cancer. 2011;128:908-919.
-
(2011)
Int J Cancer
, vol.128
, pp. 908-919
-
-
Bhat, R.1
Dempe, S.2
Dinsart, C.3
Rommelaere, J.4
-
201
-
-
34047262198
-
Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus
-
Diaz RM, Galivo F, Kottke T, et al. Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus. Cancer Res. 2007;67: 2840-2848.
-
(2007)
Cancer Res
, vol.67
, pp. 2840-2848
-
-
Diaz, R.M.1
Galivo, F.2
Kottke, T.3
-
202
-
-
77953172635
-
Type III IFN interleukin-28 mediates the antitumor eff icacy of oncolytic virus VSV in immune-competent mouse models of cancer
-
Wongthida P, Diaz RM, Galivo F, et al. Type III IFN interleukin-28 mediates the antitumor eff icacy of oncolytic virus VSV in immune-competent mouse models of cancer. Cancer Res. 2010;70: 4539-4549.
-
(2010)
Cancer Res
, vol.70
, pp. 4539-4549
-
-
Wongthida, P.1
Diaz, R.M.2
Galivo, F.3
-
203
-
-
0037295403
-
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumor properties
-
Liu BL, Robinson M, Han ZQ, et al. ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumor properties. Gene Ther. 2003;10:292-303.
-
(2003)
Gene Ther
, vol.10
, pp. 292-303
-
-
Liu, B.L.1
Robinson, M.2
Han, Z.Q.3
-
204
-
-
45749096230
-
Treg depletion-enhanced IL-2 treatment facilitates therapy of established tumors using systemically delivered oncolytic virus
-
Kottke T, Galivo F, Wongthida P, et al. Treg depletion-enhanced IL-2 treatment facilitates therapy of established tumors using systemically delivered oncolytic virus. Mol Ther. 2008;16:1217-1226.
-
(2008)
Mol Ther
, vol.16
, pp. 1217-1226
-
-
Kottke, T.1
Galivo, F.2
Wongthida, P.3
-
205
-
-
0029070112
-
IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases
-
Bronte V, Tsung K, Rao JB, et al. IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases. J Immunol. 15 1995;154:5282-5292.
-
(1995)
J Immunol
, vol.154
, Issue.15
, pp. 5282-5292
-
-
Bronte, V.1
Tsung, K.2
Rao, J.B.3
-
206
-
-
33750332951
-
Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model
-
Lee YS, Kim JH, Choi KJ, et al. Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model. Clin Cancer Res. 2006;12:5859-5868.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5859-5868
-
-
Lee, Y.S.1
Kim, J.H.2
Choi, K.J.3
-
207
-
-
73349133717
-
Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma
-
Senzer NN, Kaufman HL, Amatruda T, et al. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma. J Clin Oncol. 2009;27:5763-5771.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5763-5771
-
-
Senzer, N.N.1
Kaufman, H.L.2
Amatruda, T.3
-
208
-
-
33845336115
-
A phase I study of OncoVEXGMCSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor
-
Hu JC, Coffin RS, Davis CJ, et al. A phase I study of OncoVEXGMCSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res. 2006;12:6737-6747.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6737-6747
-
-
Hu, J.C.1
Coffin, R.S.2
Davis, C.J.3
-
209
-
-
77955104827
-
Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck
-
Harrington KJ, Hingorani M, Tanay MA, et al. Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck. Clin Cancer Res. 2010;16:4005-4015.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4005-4015
-
-
Harrington, K.J.1
Hingorani, M.2
Tanay, M.A.3
-
210
-
-
77149141965
-
Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma
-
Kaufman HL, Kim DW, Deraffele G, et al. Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma. Ann Surg Oncol. 2010;17:718-730.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 718-730
-
-
Kaufman, H.L.1
Kim, D.W.2
Deraffele, G.3
-
211
-
-
44249100151
-
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: A phase I trial
-
Park BH, Hwang T, Liu TC, et al. Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial. Lancet Oncol. 2008;9:533-542.
-
(2008)
Lancet Oncol
, vol.9
, pp. 533-542
-
-
Park, B.H.1
Hwang, T.2
Liu, T.C.3
-
212
-
-
66149098502
-
A phase I study of KH901, a conditionally replicating granulocyte-macrophage colony-stimulating factor: Armed oncolytic adenovirus for the treatment of head and neck cancers
-
Chang J, Zhao X, Wu X, et al. A phase I study of KH901, a conditionally replicating granulocyte-macrophage colony-stimulating factor: armed oncolytic adenovirus for the treatment of head and neck cancers. Cancer Biol Ther. 2009;8:676-682.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 676-682
-
-
Chang, J.1
Zhao, X.2
Wu, X.3
-
213
-
-
60549100362
-
Antitumoral immune response by recruitment and expansion of dendritic cells in tumors infected with telomerase-dependent oncolytic viruses
-
Ramakrishna E, Woller N, Mundt B, et al. Antitumoral immune response by recruitment and expansion of dendritic cells in tumors infected with telomerase-dependent oncolytic viruses. Cancer Res. 2009; 69:1448-1458.
-
(2009)
Cancer Res
, vol.69
, pp. 1448-1458
-
-
Ramakrishna, E.1
Woller, N.2
Mundt, B.3
-
214
-
-
20144382769
-
Assessment of a combined, adenovirus-mediated oncolytic and immunostimulatory tumor therapy
-
Bernt KM, Ni S, Tieu AT, Lieber A. Assessment of a combined, adenovirus-mediated oncolytic and immunostimulatory tumor therapy. Cancer Res. 2005;65:4343-4352.
-
(2005)
Cancer Res
, vol.65
, pp. 4343-4352
-
-
Bernt, K.M.1
Ni, S.2
Tieu, A.T.3
Lieber, A.4
-
215
-
-
79953327283
-
Chemokine expression from oncolytic vaccinia virus enhances vaccine therapies of cancer
-
Li J, O'Malley M, Urban J, et al. Chemokine expression from oncolytic vaccinia virus enhances vaccine therapies of cancer. Mol Ther. 2011; 19:650-657.
-
(2011)
Mol Ther
, vol.19
, pp. 650-657
-
-
Li, J.1
O'Malley, M.2
Urban, J.3
-
216
-
-
63649137545
-
Targeting the intratumoral dendritic cells by the oncolytic adenoviral vaccine expressing RANTES elicits potent antitumor immunity
-
Lapteva N, Aldrich M, Weksberg D, et al. Targeting the intratumoral dendritic cells by the oncolytic adenoviral vaccine expressing RANTES elicits potent antitumor immunity. J Immunother. 2009;32:145-156.
-
(2009)
J Immunother
, vol.32
, pp. 145-156
-
-
Lapteva, N.1
Aldrich, M.2
Weksberg, D.3
-
217
-
-
20244374204
-
Cytokine gene transfer enhances herpes oncolytic therapy in murine squamous cell carcinoma
-
Wong RJ, Patel SG, Kim S, et al. Cytokine gene transfer enhances herpes oncolytic therapy in murine squamous cell carcinoma. Hum Gene Ther. 2001;12:253-265.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 253-265
-
-
Wong, R.J.1
Patel, S.G.2
Kim, S.3
-
218
-
-
33746916507
-
Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF
-
Kim JH, Oh JY, Park BH, et al. Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF. Mol Ther. 2006;14:361-370.
-
(2006)
Mol Ther
, vol.14
, pp. 361-370
-
-
Kim, J.H.1
Oh, J.Y.2
Park, B.H.3
-
219
-
-
74549226667
-
Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model
-
Lee JH, Roh MS, Lee YK, et al. Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model. Cancer Gene Ther. 2010;17:73-79.
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 73-79
-
-
Lee, J.H.1
Roh, M.S.2
Lee, Y.K.3
-
220
-
-
77953160443
-
Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients
-
Cerullo V, Pesonen S, Diaconu I, et al. Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients. Cancer Res. 2010;70:4297-4309.
-
(2010)
Cancer Res
, vol.70
, pp. 4297-4309
-
-
Cerullo, V.1
Pesonen, S.2
Diaconu, I.3
-
221
-
-
64049109524
-
Novel immunocompetent murine tumor model for evaluation of conditionally replication-competent (oncolytic) murine adenoviral vectors
-
Robinson M, Li B, Ge Y, et al. Novel immunocompetent murine tumor model for evaluation of conditionally replication-competent (oncolytic) murine adenoviral vectors. J Virol. 2009;83:3450-3462.
-
(2009)
J Virol
, vol.83
, pp. 3450-3462
-
-
Robinson, M.1
Li, B.2
Ge, Y.3
-
222
-
-
34548552691
-
Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus
-
Vigil A, Park MS, Martinez O, et al. Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus. Cancer Res. 2007;67:8285-8292.
-
(2007)
Cancer Res
, vol.67
, pp. 8285-8292
-
-
Vigil, A.1
Park, M.S.2
Martinez, O.3
-
223
-
-
0141953995
-
Neutrophils contribute to the measles virus-induced antitumor effect: Enhancement by granulocyte macrophage colony-stimulating factor expression
-
Grote D, Cattaneo R, Fielding AK. Neutrophils contribute to the measles virus-induced antitumor effect: enhancement by granulocyte macrophage colony-stimulating factor expression. Cancer Res. 2003; 63:6463-6468.
-
(2003)
Cancer Res
, vol.63
, pp. 6463-6468
-
-
Grote, D.1
Cattaneo, R.2
Fielding, A.K.3
-
224
-
-
34250327496
-
Treatment of implanted mammary tumors with recombinant vesicular stomatitis virus targeted to Her2/neu
-
Bergman I, Griffin JA, Gao Y, Whitaker-Dowling P. Treatment of implanted mammary tumors with recombinant vesicular stomatitis virus targeted to Her2/neu. Int J Cancer. 2007;121:425-430.
-
(2007)
Int J Cancer
, vol.121
, pp. 425-430
-
-
Bergman, I.1
Griffin, J.A.2
Gao, Y.3
Whitaker-Dowling, P.4
-
225
-
-
80052588142
-
Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rbeta(2) or IL-18Ralpha
-
Choi IK, Lee JS, Zhang SN, et al. Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rbeta(2) or IL-18Ralpha. Gene Ther. 2011;18:898-909.
-
(2011)
Gene Ther
, vol.18
, pp. 898-909
-
-
Choi, I.K.1
Lee, J.S.2
Zhang, S.N.3
-
226
-
-
32844475008
-
Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers
-
Varghese S, Rabkin SD, Liu R, et al. Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers. Cancer Gene Ther. 2006; 13:253-265.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 253-265
-
-
Varghese, S.1
Rabkin, S.D.2
Liu, R.3
-
227
-
-
34249086265
-
Cytokine-secreting herpes viral mutants effectively treat tumor in a murine metastatic colorectal liver model by oncolytic and T-cell-dependent mechanisms
-
Derubertis BG, Stiles BM, Bhargava A, et al. Cytokine-secreting herpes viral mutants effectively treat tumor in a murine metastatic colorectal liver model by oncolytic and T-cell-dependent mechanisms. Cancer Gene Ther. 2007;14:590-597.
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 590-597
-
-
Derubertis, B.G.1
Stiles, B.M.2
Bhargava, A.3
-
228
-
-
33846809233
-
Interleukin-12 expression enhances vesicular stomatitis virus oncolytic therapy in murine squamous cell carcinoma
-
Shin EJ, Wanna GB, Choi B, et al. Interleukin-12 expression enhances vesicular stomatitis virus oncolytic therapy in murine squamous cell carcinoma. Laryngoscope. 2007;117:210-214.
-
(2007)
Laryngoscope
, vol.117
, pp. 210-214
-
-
Shin, E.J.1
Wanna, G.B.2
Choi, B.3
-
229
-
-
46049109297
-
Recombinant Newcastle disease virus expressing human interleukin-2 serves as a potential candidate for tumor therapy
-
Zhao H, Janke M, Fournier P, Schirrmacher V. Recombinant Newcastle disease virus expressing human interleukin-2 serves as a potential candidate for tumor therapy. Virus Res. 2008;136:75-80.
-
(2008)
Virus Res
, vol.136
, pp. 75-80
-
-
Zhao, H.1
Janke, M.2
Fournier, P.3
Schirrmacher, V.4
-
230
-
-
0034856629
-
A novel approach to cancer therapy using an oncolytic herpes virus to package amplicons containing cytokine genes
-
Carew JF, Kooby DA, Halterman MW, et al. A novel approach to cancer therapy using an oncolytic herpes virus to package amplicons containing cytokine genes. Mol Ther. 2001;4:250-256.
-
(2001)
Mol Ther
, vol.4
, pp. 250-256
-
-
Carew, J.F.1
Kooby, D.A.2
Halterman, M.W.3
-
231
-
-
34547092699
-
Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4
-
Post DE, Sandberg EM, Kyle MM, et al. Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4. Cancer Res. 2007;67:6872-6881.
-
(2007)
Cancer Res
, vol.67
, pp. 6872-6881
-
-
Post, D.E.1
Sandberg, E.M.2
Kyle, M.M.3
-
232
-
-
31544468273
-
Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models
-
Terada K, Wakimoto H, Tyminski E, et al. Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models. Gene Ther. 2006;13: 705-714.
-
(2006)
Gene Ther
, vol.13
, pp. 705-714
-
-
Terada, K.1
Wakimoto, H.2
Tyminski, E.3
-
233
-
-
28244502278
-
Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin-18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system
-
Fukuhara H, Ino Y, Kuroda T, et al. Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin-18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Res. 2005;65:10663-10668.
-
(2005)
Cancer Res
, vol.65
, pp. 10663-10668
-
-
Fukuhara, H.1
Ino, Y.2
Kuroda, T.3
-
234
-
-
31544455030
-
Triple combination of oncolytic herpes simplex virus-1 vectors armed with interleukin-12, interleukin-18, or soluble B7-1 results in enhanced antitumor efficacy
-
Ino Y, Saeki Y, Fukuhara H, Todo T. Triple combination of oncolytic herpes simplex virus-1 vectors armed with interleukin-12, interleukin-18, or soluble B7-1 results in enhanced antitumor efficacy. Clin Cancer Res. 2006;12:643-652.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 643-652
-
-
Ino, Y.1
Saeki, Y.2
Fukuhara, H.3
Todo, T.4
-
235
-
-
38349019847
-
Anticancer activity of oncolytic adenovirus vector armed with IFN-alpha and ADP is enhanced by pharmacologically controlled expression of TRAIL
-
Shashkova EV, Kuppuswamy MN, Wold WS, Doronin K. Anticancer activity of oncolytic adenovirus vector armed with IFN-alpha and ADP is enhanced by pharmacologically controlled expression of TRAIL. Cancer Gene Ther. 2008;15:61-72.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 61-72
-
-
Shashkova, E.V.1
Kuppuswamy, M.N.2
Wold, W.S.3
Doronin, K.4
-
236
-
-
33847210729
-
Targeting interferon-alpha increases antitumor efficacy and reduces hepatotoxicity of E1A-mutated spread-enhanced oncolytic adenovirus
-
Shashkova EV, Spencer JF, Wold WS, Doronin K. Targeting interferon-alpha increases antitumor efficacy and reduces hepatotoxicity of E1A-mutated spread-enhanced oncolytic adenovirus. Mol Ther. 2007;15:598-607.
-
(2007)
Mol Ther
, vol.15
, pp. 598-607
-
-
Shashkova, E.V.1
Spencer, J.F.2
Wold, W.S.3
Doronin, K.4
-
237
-
-
38049017526
-
Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus
-
Kirn DH, Wang Y, Le Boeuf F, et al. Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus. PLoS Med. 2007;4:e353.
-
(2007)
PLoS Med
, vol.4
-
-
Kirn, D.H.1
Wang, Y.2
le Boeuf, F.3
-
238
-
-
70350230280
-
Expression of IFN-beta enhances both efficacy and safety of oncolytic vesicular stomatitis virus for therapy of mesothelioma
-
Willmon CL, Saloura V, Fridlender ZG, et al. Expression of IFN-beta enhances both efficacy and safety of oncolytic vesicular stomatitis virus for therapy of mesothelioma. Cancer Res. 2009;69:7713-7720.
-
(2009)
Cancer Res
, vol.69
, pp. 7713-7720
-
-
Willmon, C.L.1
Saloura, V.2
Fridlender, Z.G.3
-
239
-
-
33645840128
-
Immune gene-viral therapy with triplex efficacy mediated by oncolytic adenovirus carrying an interferongamma gene yields efficient antitumor activity in immunodeficient and immunocompetent mice
-
Su C, Peng L, Sham J, et al. Immune gene-viral therapy with triplex efficacy mediated by oncolytic adenovirus carrying an interferongamma gene yields efficient antitumor activity in immunodeficient and immunocompetent mice. Mol Ther. 2006;13:918-927.
-
(2006)
Mol Ther
, vol.13
, pp. 918-927
-
-
Su, C.1
Peng, L.2
Sham, J.3
-
240
-
-
33947375243
-
Development of a secondgeneration oncolytic Herpes simplex virus expressing TNFalpha for cancer therapy
-
Han ZQ, Assenberg M, Liu BL, et al. Development of a secondgeneration oncolytic Herpes simplex virus expressing TNFalpha for cancer therapy. J Gene Med. 2007;9:99-106.
-
(2007)
J Gene Med
, vol.9
, pp. 99-106
-
-
Han, Z.Q.1
Assenberg, M.2
Liu, B.L.3
-
241
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol. 2003;3:133-146.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
242
-
-
0032858174
-
Distinct role of antigenspecific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo
-
Nishimura T, Iwakabe K, Sekimoto M, et al. Distinct role of antigenspecific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo. J Exp Med. 1999;190:617-627.
-
(1999)
J Exp Med
, vol.190
, pp. 617-627
-
-
Nishimura, T.1
Iwakabe, K.2
Sekimoto, M.3
-
245
-
-
0035870277
-
Interleukin-12-activated lymphocytes influence tumor genetic programs
-
Cavallo F, Quaglino E, Cifaldi L, et al. Interleukin-12-activated lymphocytes influence tumor genetic programs. Cancer Res. 2001;61: 3518-3523.
-
(2001)
Cancer Res
, vol.61
, pp. 3518-3523
-
-
Cavallo, F.1
Quaglino, E.2
Cifaldi, L.3
-
246
-
-
0033104852
-
Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12
-
Yao L, Sgadari C, Furuke K, et al. Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12. Blood. 1999; 93:1612-1621.
-
(1999)
Blood
, vol.93
, pp. 1612-1621
-
-
Yao, L.1
Sgadari, C.2
Furuke, K.3
-
247
-
-
17344383269
-
Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis
-
Coughlin CM, Salhany KE, Gee MS, et al. Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis. Immunity. 1998;9:25-34.
-
(1998)
Immunity
, vol.9
, pp. 25-34
-
-
Coughlin, C.M.1
Salhany, K.E.2
Gee, M.S.3
-
248
-
-
0027963161
-
Recombinant IL-12 administration induces tumor regression in association with IFNgamma production
-
Nastala CL, Edington HD, McKinney TG, et al. Recombinant IL-12 administration induces tumor regression in association with IFNgamma production. J Immunol. 1994;153:1697-1706.
-
(1994)
J Immunol
, vol.153
, pp. 1697-1706
-
-
Nastala, C.L.1
Edington, H.D.2
McKinney, T.G.3
-
249
-
-
0027953555
-
Fibroblasts genetically engineered to secrete interleukin-12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo
-
Tahara H, Zeh HJ 3rd, Storkus WJ, et al. Fibroblasts genetically engineered to secrete interleukin-12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo. Cancer Res. 1994;54:182-189.
-
(1994)
Cancer Res
, vol.54
, pp. 182-189
-
-
Tahara, H.1
Zeh III, H.J.2
Storkus, W.J.3
-
251
-
-
34548067624
-
Interleukin-12: Biological properties and clinical application
-
Del Vecchio M, Bajetta E, Canova S, et al. Interleukin-12: biological properties and clinical application. Clin Cancer Res. 2007;13: 4677-4685.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4677-4685
-
-
del Vecchio, M.1
Bajetta, E.2
Canova, S.3
-
252
-
-
0030766971
-
Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production
-
Leonard JP, Sherman ML, Fisher GL, et al. Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production. Blood. 1997;90:2541-2548.
-
(1997)
Blood
, vol.90
, pp. 2541-2548
-
-
Leonard, J.P.1
Sherman, M.L.2
Fisher, G.L.3
-
253
-
-
0028603492
-
Biologic effects of recombinant human interleukin-12 in squirrel monkeys (Sciureus saimiri)
-
Sarmiento UM, Riley JH, Knaack PA, et al. Biologic effects of recombinant human interleukin-12 in squirrel monkeys (Sciureus saimiri). Lab Invest. 1994;71:862-873.
-
(1994)
Lab Invest
, vol.71
, pp. 862-873
-
-
Sarmiento, U.M.1
Riley, J.H.2
Knaack, P.A.3
-
254
-
-
0028824039
-
IL-12 deaths: Explanation and a puzzle
-
Cohen J. IL-12 deaths: explanation and a puzzle. Science. 1995; 270:908.
-
(1995)
Science
, vol.270
, pp. 908
-
-
Cohen, J.1
-
255
-
-
0028968497
-
Administration of recombinant interleukin-12 to mice suppresses hematopoiesis in the bone marrow but enhances hematopoiesis in the spleen
-
Tare NS, Bowen S, Warrier RR, et al. Administration of recombinant interleukin-12 to mice suppresses hematopoiesis in the bone marrow but enhances hematopoiesis in the spleen. J Interferon Cytokine Res.1995;15:377-383.
-
(1995)
J Interferon Cytokine Res
, vol.15
, pp. 377-383
-
-
Tare, N.S.1
Bowen, S.2
Warrier, R.R.3
-
256
-
-
0036173196
-
Systemic administration of naked DNA encoding interleukin-12 for the treatment of human papillomavirus DNA-positive tumor
-
Lui VW, He Y, Falo L, Huang L. Systemic administration of naked DNA encoding interleukin-12 for the treatment of human papillomavirus DNA-positive tumor. Hum Gene Ther. 2002;13:177-185.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 177-185
-
-
Lui, V.W.1
He, Y.2
Falo, L.3
Huang, L.4
-
257
-
-
0034050884
-
Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors
-
Parker JN, Gillespie GY, Love CE, et al. Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proc Natl Acad Sci U S A. 2000;97:2208-2213.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2208-2213
-
-
Parker, J.N.1
Gillespie, G.Y.2
Love, C.E.3
-
258
-
-
0037345805
-
Neoadjuvant treatment of hepatic malignancy: An oncolytic herpes simplex virus expressing IL-12 effectively treats the parent tumor and protects against recurrence-after resection
-
Jarnagin WR, Zager JS, Klimstra D, et al. Neoadjuvant treatment of hepatic malignancy: an oncolytic herpes simplex virus expressing IL-12 effectively treats the parent tumor and protects against recurrence-after resection. Cancer Gene Ther. 2003;10: 215-223.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 215-223
-
-
Jarnagin, W.R.1
Zager, J.S.2
Klimstra, D.3
-
259
-
-
1642535483
-
Effective intravenous therapy of murine pulmonary metastases with an oncolytic herpes virus expressing interleukin-12
-
Wong RJ, Chan MK, Yu Z, et al. Effective intravenous therapy of murine pulmonary metastases with an oncolytic herpes virus expressing interleukin-12. Clin Cancer Res. 2004;10:251-259.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 251-259
-
-
Wong, R.J.1
Chan, M.K.2
Yu, Z.3
-
260
-
-
33745191473
-
Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect
-
Choi KJ, Kim JH, Lee YS, et al. Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect. Gene Ther. 2006;13:1010-1020.
-
(2006)
Gene Ther
, vol.13
, pp. 1010-1020
-
-
Choi, K.J.1
Kim, J.H.2
Lee, Y.S.3
-
261
-
-
70350536582
-
Host lymphodepletion enhances the therapeutic activity of an oncolytic vaccinia virus expressing 4-1BB ligand
-
Kim HS, Kim-Schulze S, Kim DW, Kaufman HL. Host lymphodepletion enhances the therapeutic activity of an oncolytic vaccinia virus expressing 4-1BB ligand. Cancer Res. 2009;69:8516-8525.
-
(2009)
Cancer Res
, vol.69
, pp. 8516-8525
-
-
Kim, H.S.1
Kim-Schulze, S.2
Kim, D.W.3
Kaufman, H.L.4
-
262
-
-
76349109690
-
Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL
-
Huang JH, Zhang SN, Choi KJ, et al. Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL. Mol Ther. 2010;18: 264-274.
-
(2010)
Mol Ther
, vol.18
, pp. 264-274
-
-
Huang, J.H.1
Zhang, S.N.2
Choi, K.J.3
-
263
-
-
77950933188
-
Interference of CD40Lmediated tumor immunotherapy by oncolytic VSV
-
Galivo F, Diaz RM, Thanarajasingam U, et al. Interference of CD40Lmediated tumor immunotherapy by oncolytic VSV. Hum Gene Ther. 2010;21:439-450.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 439-450
-
-
Galivo, F.1
Diaz, R.M.2
Thanarajasingam, U.3
-
264
-
-
0035138174
-
In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity
-
Todo T, Martuza RL, Dallman MJ, Rabkin SD. In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity. Cancer Res. 2001;61:153-161.
-
(2001)
Cancer Res
, vol.61
, pp. 153-161
-
-
Todo, T.1
Martuza, R.L.2
Dallman, M.J.3
Rabkin, S.D.4
-
265
-
-
62549085594
-
A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients
-
Li JL, Liu HL, Zhang XR, et al. A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients. Gene Ther. 2009;16:376-382.
-
(2009)
Gene Ther
, vol.16
, pp. 376-382
-
-
Li, J.L.1
Liu, H.L.2
Zhang, X.R.3
-
266
-
-
77955639966
-
Tumor suppression by apoptotic and anti-angiogenic effects of mortalin-targeting adeno-oncolytic virus
-
Yoo JY, Ryu J, Gao R, et al. Tumor suppression by apoptotic and anti-angiogenic effects of mortalin-targeting adeno-oncolytic virus. J Gene Med. 2010;12:586-595.
-
(2010)
J Gene Med
, vol.12
, pp. 586-595
-
-
Yoo, J.Y.1
Ryu, J.2
Gao, R.3
-
267
-
-
31544471137
-
Effect of adenovirus-mediated heat shock protein expression and oncolysis in combination with low-dose cyclophosphamide treatment on antitumor immune responses
-
Di Paolo NC, Tuve S, Ni S, et al. Effect of adenovirus-mediated heat shock protein expression and oncolysis in combination with low-dose cyclophosphamide treatment on antitumor immune responses. Cancer Res. 2006;66:960-969.
-
(2006)
Cancer Res
, vol.66
, pp. 960-969
-
-
di Paolo, N.C.1
Tuve, S.2
Ni, S.3
-
268
-
-
10744224810
-
A broadly applicable, personalized heat shock protein-mediated oncolytic tumor vaccine
-
Huang XF, Ren W, Rollins L, et al. A broadly applicable, personalized heat shock protein-mediated oncolytic tumor vaccine. Cancer Res. 2003;63:7321-7329.
-
(2003)
Cancer Res
, vol.63
, pp. 7321-7329
-
-
Huang, X.F.1
Ren, W.2
Rollins, L.3
-
269
-
-
39049140856
-
A simplified system for generating oncolytic adenovirus vector carrying one or two transgenes
-
Hu ZB, Wu CT, Wang H, et al. A simplified system for generating oncolytic adenovirus vector carrying one or two transgenes. Cancer Gene Ther. 2008;15:173-182.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 173-182
-
-
Hu, Z.B.1
Wu, C.T.2
Wang, H.3
-
270
-
-
5144235393
-
Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen
-
Lonchay C, van der Bruggen P, Connerotte T, et al. Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen. Proc Natl Acad Sci U S A. 2004; 101(Suppl 2):14631-14638.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.SUPPL. 2
, pp. 14631-14638
-
-
Lonchay, C.1
van der Bruggen, P.2
Connerotte, T.3
-
271
-
-
33745223435
-
Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: A phase I/II trial
-
Harrop R, Connolly N, Redchenko I, et al. Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial. Clin Cancer Res. 2006;12: 3416-3424.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3416-3424
-
-
Harrop, R.1
Connolly, N.2
Redchenko, I.3
-
272
-
-
48549088424
-
Vaccination of prostate cancer patients with modified vaccinia ankara delivering the tumor antigen 5T4 (TroVax): A phase 2 trial
-
Amato RJ, Drury N, Naylor S, et al. Vaccination of prostate cancer patients with modified vaccinia ankara delivering the tumor antigen 5T4 (TroVax): a phase 2 trial. J Immunother. 2008;31:577-585.
-
(2008)
J Immunother
, vol.31
, pp. 577-585
-
-
Amato, R.J.1
Drury, N.2
Naylor, S.3
-
273
-
-
51049083164
-
Combination chemotherapy and ALVAC-CEA/B7.1 vaccine in patients with metastatic colorectal cancer
-
Kaufman HL, Lenz HJ, Marshall J, et al. Combination chemotherapy and ALVAC-CEA/B7.1 vaccine in patients with metastatic colorectal cancer. Clin Cancer Res. 2008;14:4843-4849.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4843-4849
-
-
Kaufman, H.L.1
Lenz, H.J.2
Marshall, J.3
-
274
-
-
0033766694
-
Phase I clinical trial of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen and the B7.1 co-stimulatory molecule
-
Horig H, Lee DS, Conkright W, et al. Phase I clinical trial of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen and the B7.1 co-stimulatory molecule. Cancer Immunol Immunother. 2000;49:504-514.
-
(2000)
Cancer Immunol Immunother
, vol.49
, pp. 504-514
-
-
Horig, H.1
Lee, D.S.2
Conkright, W.3
-
276
-
-
0035892365
-
Immunization with type 5 adenovirus recombinant for a tumor antigen in combination with recombinant canarypox virus (ALVAC) cytokine gene delivery induces destruction of established prostate tumors
-
Elzey BD, Siemens DR, Ratliff TL, Lubaroff DM. Immunization with type 5 adenovirus recombinant for a tumor antigen in combination with recombinant canarypox virus (ALVAC) cytokine gene delivery induces destruction of established prostate tumors. Int J Cancer. 2001; 94:842-849.
-
(2001)
Int J Cancer
, vol.94
, pp. 842-849
-
-
Elzey, B.D.1
Siemens, D.R.2
Ratliff, T.L.3
Lubaroff, D.M.4
-
277
-
-
0030663697
-
Enhancing efficacy of recombinant anticancer vaccines with prime/boost regimens that use two different vectors
-
Irvine KR, Chamberlain RS, Shulman EP, et al. Enhancing efficacy of recombinant anticancer vaccines with prime/boost regimens that use two different vectors. J Natl Cancer Inst. 1997;89:1595-1601.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1595-1601
-
-
Irvine, K.R.1
Chamberlain, R.S.2
Shulman, E.P.3
-
278
-
-
34249782279
-
Comparative prime-boost vaccinations using Semliki Forest virus, adenovirus, and ALVAC vectors demonstrate differences in the generation of a protective central memory CTL response against the P815 tumor
-
Naslund TI, Uyttenhove C, Nordstrom EK, et al. Comparative prime-boost vaccinations using Semliki Forest virus, adenovirus, and ALVAC vectors demonstrate differences in the generation of a protective central memory CTL response against the P815 tumor. J Immunol. 2007;178:6761-6769.
-
(2007)
J Immunol
, vol.178
, pp. 6761-6769
-
-
Naslund, T.I.1
Uyttenhove, C.2
Nordstrom, E.K.3
-
279
-
-
0344412934
-
Modified vaccinia virus ankara recombinants are as potent as vaccinia recombinants in diversified prime and boost vaccine regimens to elicit therapeutic antitumor responses
-
Hodge JW, Poole DJ, Aarts WM, et al. Modified vaccinia virus ankara recombinants are as potent as vaccinia recombinants in diversified prime and boost vaccine regimens to elicit therapeutic antitumor responses. Cancer Res. 2003;63:7942-7949.
-
(2003)
Cancer Res
, vol.63
, pp. 7942-7949
-
-
Hodge, J.W.1
Poole, D.J.2
Aarts, W.M.3
-
280
-
-
0030988548
-
Diversified prime and boost protocols using recombinant vaccinia virus and recombinant non-replicating avian pox virus to enhance T-cell immunity and antitumor responses
-
Hodge JW, McLaughlin JP, Kantor JA, Schlom J. Diversified prime and boost protocols using recombinant vaccinia virus and recombinant non-replicating avian pox virus to enhance T-cell immunity and antitumor responses. Vaccine. 1997;15:759-768.
-
(1997)
Vaccine
, vol.15
, pp. 759-768
-
-
Hodge, J.W.1
McLaughlin, J.P.2
Kantor, J.A.3
Schlom, J.4
-
281
-
-
0034551730
-
Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
-
Marshall JL, Hoyer RJ, Toomey MA, et al. Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses. J Clin Oncol. 2000;18:3964-3973.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3964-3973
-
-
Marshall, J.L.1
Hoyer, R.J.2
Toomey, M.A.3
-
282
-
-
54949143615
-
Recombinant Newcastle disease virus as a vaccine vector for cancer therapy
-
Vigil A, Martinez O, Chua MA, Garcia-Sastre A. Recombinant Newcastle disease virus as a vaccine vector for cancer therapy. Mol Ther. 2008;16:1883-1890.
-
(2008)
Mol Ther
, vol.16
, pp. 1883-1890
-
-
Vigil, A.1
Martinez, O.2
Chua, M.A.3
Garcia-Sastre, A.4
-
283
-
-
33947190925
-
Cell-based delivery of oncolytic viruses: A new strategic alliance for a biological strike against cancer
-
Power AT, Bell JC. Cell-based delivery of oncolytic viruses: a new strategic alliance for a biological strike against cancer. Mol Ther. 2007; 15:660-665.
-
(2007)
Mol Ther
, vol.15
, pp. 660-665
-
-
Power, A.T.1
Bell, J.C.2
-
284
-
-
79955520856
-
Internalization of oncolytic reovirus by human dendritic cell carriers protects the virus from neutralization
-
Ilett EJ, Barcena M, Errington-Mais F, et al. Internalization of oncolytic reovirus by human dendritic cell carriers protects the virus from neutralization. Clin Cancer Res. 2011;17:2767-2776.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2767-2776
-
-
Ilett, E.J.1
Barcena, M.2
Errington-Mais, F.3
-
285
-
-
77953137806
-
Systemic therapy of disseminated myeloma in passively immunized mice using measles virus-infected cell carriers
-
Liu C, Russell SJ, Peng KW. Systemic therapy of disseminated myeloma in passively immunized mice using measles virus-infected cell carriers. Mol Ther. 2010;18:1155-1164.
-
(2010)
Mol Ther
, vol.18
, pp. 1155-1164
-
-
Liu, C.1
Russell, S.J.2
Peng, K.W.3
-
286
-
-
73149102956
-
Mesenchymal stem cell carriers protect oncolytic measles viruses from antibody neutralization in an orthotopic ovarian cancer therapy model
-
Mader EK, Maeyama Y, Lin Y, et al. Mesenchymal stem cell carriers protect oncolytic measles viruses from antibody neutralization in an orthotopic ovarian cancer therapy model. Clin Cancer Res. 2009;15: 7246-7255.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7246-7255
-
-
Mader, E.K.1
Maeyama, Y.2
Lin, Y.3
-
287
-
-
38049051428
-
Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy
-
Qiao J, Kottke T, Willmon C, et al. Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy. Nat Med. 2008;14: 37-44.
-
(2008)
Nat Med
, vol.14
, pp. 37-44
-
-
Qiao, J.1
Kottke, T.2
Willmon, C.3
-
288
-
-
34249776097
-
Local and distant immunemediated control of colon cancer growth with fusogenic membrane glycoproteins in combination with viral oncolysis
-
Hoffmann D, Bayer W, Wildner O. Local and distant immunemediated control of colon cancer growth with fusogenic membrane glycoproteins in combination with viral oncolysis. Hum Gene Ther. 2007;18:435-450.
-
(2007)
Hum Gene Ther
, vol.18
, pp. 435-450
-
-
Hoffmann, D.1
Bayer, W.2
Wildner, O.3
-
289
-
-
4944243251
-
Targeted delivery of adenoviral vectors by cytotoxic T cells
-
Yotnda P, Savoldo B, Charlet-Berguerand N, et al. Targeted delivery of adenoviral vectors by cytotoxic T cells. Blood. 2004;104: 2272-2280.
-
(2004)
Blood
, vol.104
, pp. 2272-2280
-
-
Yotnda, P.1
Savoldo, B.2
Charlet-Berguerand, N.3
-
290
-
-
77956267058
-
Targeting localized immune suppression within the tumor through repeat cycles of immune cell-oncolytic virus combination therapy
-
Thorne SH, Liang W, Sampath P, et al. Targeting localized immune suppression within the tumor through repeat cycles of immune cell-oncolytic virus combination therapy. Mol Ther. 2010;18:1698-1705.
-
(2010)
Mol Ther
, vol.18
, pp. 1698-1705
-
-
Thorne, S.H.1
Liang, W.2
Sampath, P.3
-
291
-
-
80054094100
-
Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors
-
Thomas DL, Doty R, Tosic V, et al. Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors. Cancer Immunol Immunother. 2011;60: 1461-1472.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1461-1472
-
-
Thomas, D.L.1
Doty, R.2
Tosic, V.3
-
292
-
-
33645239282
-
Synergistic antitumor effects of immune cell-viral biotherapy
-
Thorne SH, Negrin RS, Contag CH. Synergistic antitumor effects of immune cell-viral biotherapy. Science. 2006;311:1780-1784.
-
(2006)
Science
, vol.311
, pp. 1780-1784
-
-
Thorne, S.H.1
Negrin, R.S.2
Contag, C.H.3
-
293
-
-
34548052482
-
Combined oncolytic and vaccination activities of parvovirus H-1 in a metastatic tumor model
-
Raykov Z, Grekova S, Galabov AS, et al. Combined oncolytic and vaccination activities of parvovirus H-1 in a metastatic tumor model. Oncol Rep. 2007;17:1493-1499.
-
(2007)
Oncol Rep
, vol.17
, pp. 1493-1499
-
-
Raykov, Z.1
Grekova, S.2
Galabov, A.S.3
-
294
-
-
18144363557
-
Clinical trials of antitumor vaccination with an autologous tumor cell vaccine modified by virus infection: Improvement of patient survival based on improved antitumor immune memory
-
Schirrmacher V. Clinical trials of antitumor vaccination with an autologous tumor cell vaccine modified by virus infection: improvement of patient survival based on improved antitumor immune memory. Cancer Immunol Immunother. 2005;54:587-598.
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 587-598
-
-
Schirrmacher, V.1
-
295
-
-
0032897339
-
Human tumor cell modification by virus infection: An efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle disease virus
-
Schirrmacher V, Haas C, Bonifer R, et al. Human tumor cell modification by virus infection: an efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle disease virus. Gene Ther. 1999;6:63-73.
-
(1999)
Gene Ther
, vol.6
, pp. 63-73
-
-
Schirrmacher, V.1
Haas, C.2
Bonifer, R.3
-
296
-
-
34250735062
-
Combining immune cell and viral therapy for the treatment of cancer
-
Thorne SH, Contag CH. Combining immune cell and viral therapy for the treatment of cancer. Cell Mol Life Sci. 2007;64:1449-1451.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1449-1451
-
-
Thorne, S.H.1
Contag, C.H.2
-
297
-
-
68249083949
-
Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity
-
Boudreau JE, Bridle BW, Stephenson KB, et al. Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity. Mol Ther. 2009;17:1465-1472.
-
(2009)
Mol Ther
, vol.17
, pp. 1465-1472
-
-
Boudreau, J.E.1
Bridle, B.W.2
Stephenson, K.B.3
-
298
-
-
27144511701
-
Oncolytic measles virus in cutaneous T-cell lymphomas mounts antitumor immune responses in vivo and targets interferon-resistant tumor cells
-
Heinzerling L, Kunzi V, Oberholzer PA, et al. Oncolytic measles virus in cutaneous T-cell lymphomas mounts antitumor immune responses in vivo and targets interferon-resistant tumor cells. Blood. 2005;106:2287-2294.
-
(2005)
Blood
, vol.106
, pp. 2287-2294
-
-
Heinzerling, L.1
Kunzi, V.2
Oberholzer, P.A.3
-
299
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
-
Mineta T, Rabkin SD, Yazaki T, et al. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med. 1995;1:938-943.
-
(1995)
Nat Med
, vol.1
, pp. 938-943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
-
300
-
-
77953093863
-
Two-stage phase I dose-escalation study of intratumoral reovirus type 3 dearing and palliative radiotherapy in patients with advanced cancers
-
Harrington KJ, Karapanagiotou EM, Roulstone V, et al. Two-stage phase I dose-escalation study of intratumoral reovirus type 3 dearing and palliative radiotherapy in patients with advanced cancers. Clin Cancer Res. 2010;16:3067-3077.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3067-3077
-
-
Harrington, K.J.1
Karapanagiotou, E.M.2
Roulstone, V.3
-
301
-
-
80053000452
-
Strategies to enhance viral penetration of solid tumors
-
Smith E, Breznik J, Lichty BD. Strategies to enhance viral penetration of solid tumors. Hum Gene Ther. 2011;22:1053-1060.
-
(2011)
Hum Gene Ther
, vol.22
, pp. 1053-1060
-
-
Smith, E.1
Breznik, J.2
Lichty, B.D.3
-
302
-
-
33846686516
-
Systemic efficacy with oncolytic virus therapeutics: Clinical proof-of-concept and future directions
-
Liu TC, Kirn D. Systemic efficacy with oncolytic virus therapeutics: clinical proof-of-concept and future directions. Cancer Res. 2007;67: 429-432.
-
(2007)
Cancer Res
, vol.67
, pp. 429-432
-
-
Liu, T.C.1
Kirn, D.2
-
303
-
-
0036135030
-
Antibody-sensitive and antibodyresistant cell-to-cell spread by vaccinia virus: Role of the A33R protein in antibody-resistant spread
-
Law M, Hollinshead R, Smith GL. Antibody-sensitive and antibodyresistant cell-to-cell spread by vaccinia virus: role of the A33R protein in antibody-resistant spread. J Gen Virol. 2002;83:209-222.
-
(2002)
J Gen Virol
, vol.83
, pp. 209-222
-
-
Law, M.1
Hollinshead, R.2
Smith, G.L.3
-
304
-
-
0032560578
-
Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope
-
Vanderplasschen A, Mathew E, Hollinshead M, et al. Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope. Proc Natl Acad Sci U S A. 1998;95:7544-7549.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7544-7549
-
-
Vanderplasschen, A.1
Mathew, E.2
Hollinshead, M.3
-
305
-
-
0033997183
-
Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant
-
Ikeda K, Wakimoto H, Ichikawa T, et al. Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant. J Virol. 2000;74: 4765-4775.
-
(2000)
J Virol
, vol.74
, pp. 4765-4775
-
-
Ikeda, K.1
Wakimoto, H.2
Ichikawa, T.3
-
306
-
-
0032814773
-
Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses
-
Ikeda K, Ichikawa T, Wakimoto H, et al. Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nat Med. 1999;5:881-887.
-
(1999)
Nat Med
, vol.5
, pp. 881-887
-
-
Ikeda, K.1
Ichikawa, T.2
Wakimoto, H.3
-
307
-
-
70349873326
-
Pre-existing immunity and passive immunity to adenovirus 5 prevents toxicity caused by an oncolytic adenovirus vector in the Syrian hamster model
-
Dhar D, Spencer JF, Toth K, Wold WS. Pre-existing immunity and passive immunity to adenovirus 5 prevents toxicity caused by an oncolytic adenovirus vector in the Syrian hamster model. Mol Ther. 2009;17:1724-1732.
-
(2009)
Mol Ther
, vol.17
, pp. 1724-1732
-
-
Dhar, D.1
Spencer, J.F.2
Toth, K.3
Wold, W.S.4
-
308
-
-
80053571003
-
Envelope-chimeric entrytargeted measles virus escapes neutralization and achieves oncolysis
-
May 24
-
Miest TS, Yaiw KC, Frenzke M, et al. Envelope-chimeric entrytargeted measles virus escapes neutralization and achieves oncolysis. Mol Ther. May 24, 2011.
-
(2011)
Mol Ther
-
-
Miest, T.S.1
Yaiw, K.C.2
Frenzke, M.3
-
309
-
-
48249118805
-
Measles virus as an oncolytic vector platform
-
Blechacz B, Russell SJ. Measles virus as an oncolytic vector platform. Curr Gene Ther. 2008;8:162-175.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 162-175
-
-
Blechacz, B.1
Russell, S.J.2
-
310
-
-
40749090005
-
Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus
-
Qiao J, Wang H, Kottke T, et al. Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus. Clin Cancer Res. 2008;14:259-269.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 259-269
-
-
Qiao, J.1
Wang, H.2
Kottke, T.3
-
311
-
-
0742271990
-
Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis
-
Wakimoto H, Fulci G, Tyminski E, Chiocca EA. Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis. Gene Ther. 2004;11:214-223.
-
(2004)
Gene Ther
, vol.11
, pp. 214-223
-
-
Wakimoto, H.1
Fulci, G.2
Tyminski, E.3
Chiocca, E.A.4
-
312
-
-
33744932540
-
Immunosuppression promotes reovirus therapy of colorectal liver metastases
-
Smakman N, van der Bilt JD, van den Wollenberg DJ, et al. Immunosuppression promotes reovirus therapy of colorectal liver metastases. Cancer Gene Ther. 2006;13:815-818.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 815-818
-
-
Smakman, N.1
van der Bilt, J.D.2
van den Wollenberg, D.J.3
-
313
-
-
35549009347
-
An immunocompetent murine model for oncolysis with an armed and targeted measles virus
-
Ungerechts G, Springfeld C, Frenzke ME, et al. An immunocompetent murine model for oncolysis with an armed and targeted measles virus. Mol Ther. 2007;15:1991-1997.
-
(2007)
Mol Ther
, vol.15
, pp. 1991-1997
-
-
Ungerechts, G.1
Springfeld, C.2
Frenzke, M.E.3
-
314
-
-
78651234760
-
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors
-
MacTavish H, Diallo JS, Huang B, et al. Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors. PLoS One. 2010;5:e14462.
-
(2010)
PLoS One
, vol.5
-
-
Mactavish, H.1
Diallo, J.S.2
Huang, B.3
-
315
-
-
38449114010
-
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy
-
Kurozumi K, Hardcastle J, Thakur R, et al. Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. J Natl Cancer Inst. 2007;99:1768-1781.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1768-1781
-
-
Kurozumi, K.1
Hardcastle, J.2
Thakur, R.3
-
316
-
-
44349124084
-
Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects
-
Liu TC, Castelo-Branco P, Rabkin SD, Martuza RL. Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. Mol Ther. 2008;16:1041-1047.
-
(2008)
Mol Ther
, vol.16
, pp. 1041-1047
-
-
Liu, T.C.1
Castelo-Branco, P.2
Rabkin, S.D.3
Martuza, R.L.4
-
317
-
-
69149091655
-
Anti-VEGF single-chain antibody GLAF-1 encoded by oncolytic vaccinia virus significantly enhances antitumor therapy
-
Frentzen A, Yu YA, Chen N, et al. Anti-VEGF single-chain antibody GLAF-1 encoded by oncolytic vaccinia virus significantly enhances antitumor therapy. Proc Natl Acad Sci U S A. 2009;106: 12915-12920.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12915-12920
-
-
Frentzen, A.1
Yu, Y.A.2
Chen, N.3
-
318
-
-
80052974967
-
Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: A superior oncolytic virus to dl1520 (ONYX-015) for human head and neck cancer
-
Tysome J, Wang P, Alusi G, et al. Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: a superior oncolytic virus to dl1520 (ONYX-015) for human head and neck cancer. Hum Gene Ther. 2011;22:1101-1108.
-
(2011)
Hum Gene Ther
, vol.22
, pp. 1101-1108
-
-
Tysome, J.1
Wang, P.2
Alusi, G.3
-
319
-
-
70350376151
-
Lister strain of vaccinia virus armed with endostatin-angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer
-
Tysome JR, Briat A, Alusi G, et al. Lister strain of vaccinia virus armed with endostatin-angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer. Gene Ther. 2009;16:1223-1233.
-
(2009)
Gene Ther
, vol.16
, pp. 1223-1233
-
-
Tysome, J.R.1
Briat, A.2
Alusi, G.3
-
320
-
-
72449155623
-
Combination of anti-angiogenic therapy and virotherapy: Arming oncolytic viruses with anti-angiogenic genes
-
Tysome JR, Lemoine NR, Wang Y. Combination of anti-angiogenic therapy and virotherapy: arming oncolytic viruses with anti-angiogenic genes. Curr Opin Mol Ther. 2009;11:664-669.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 664-669
-
-
Tysome, J.R.1
Lemoine, N.R.2
Wang, Y.3
-
321
-
-
42049100962
-
Gene-viral cancer therapy using dual-regulated oncolytic adenovirus with antiangiogenesis gene for increased efficacy
-
Su C, Na M, Chen J, et al. Gene-viral cancer therapy using dual-regulated oncolytic adenovirus with antiangiogenesis gene for increased efficacy. Mol Cancer Res. 2008;6:568-575.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 568-575
-
-
Su, C.1
Na, M.2
Chen, J.3
-
322
-
-
77954361990
-
Antiangiogenesis gene armed tumortargeting adenovirus yields multiple antitumor activities in human HCC xenografts in nude mice
-
Fang L, Pu YY, Hu XC, et al. Antiangiogenesis gene armed tumortargeting adenovirus yields multiple antitumor activities in human HCC xenografts in nude mice. Hepatol Res. 2009;40:216-228.
-
(2009)
Hepatol Res
, vol.40
, pp. 216-228
-
-
Fang, L.1
Pu, Y.Y.2
Hu, X.C.3
-
323
-
-
69249217795
-
Ad5/3-9HIF-delta24-VEGFR-1-Ig, an infectivity enhanced, dual-targeted and antiangiogenic oncolytic adenovirus for kidney cancer treatment
-
Guse K, Diaconu I, Rajecki M, et al. Ad5/3-9HIF-delta24-VEGFR-1-Ig, an infectivity enhanced, dual-targeted and antiangiogenic oncolytic adenovirus for kidney cancer treatment. Gene Ther. 2009;16: 1009-1020.
-
(2009)
Gene Ther
, vol.16
, pp. 1009-1020
-
-
Guse, K.1
Diaconu, I.2
Rajecki, M.3
-
324
-
-
59449108246
-
Improved systemic delivery of oncolytic reovirus to established tumors using preconditioning with cyclophosphamide-mediated Treg modulation and interleukin-2
-
Kottke T, Thompson J, Diaz RM, et al. Improved systemic delivery of oncolytic reovirus to established tumors using preconditioning with cyclophosphamide-mediated Treg modulation and interleukin-2. Clin Cancer Res. 2009;15:561-569.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 561-569
-
-
Kottke, T.1
Thompson, J.2
Diaz, R.M.3
-
325
-
-
78650880193
-
Vesicular stomatitis virus-induced immune suppressor cells generate antagonism between intratumoral oncolytic virus and cyclophosphamide
-
Willmon C, Diaz RM, Wongthida P, et al. Vesicular stomatitis virus-induced immune suppressor cells generate antagonism between intratumoral oncolytic virus and cyclophosphamide. Mol Ther. 2011; 19:140-149.
-
(2011)
Mol Ther
, vol.19
, pp. 140-149
-
-
Willmon, C.1
Diaz, R.M.2
Wongthida, P.3
-
326
-
-
80053566728
-
Precise scheduling of chemotherapy primes VEGF-producing tumors for successful systemic oncolytic virotherapy
-
July 26
-
Kottke T, Chester J, Ilett E, et al. Precise scheduling of chemotherapy primes VEGF-producing tumors for successful systemic oncolytic virotherapy. Mol Ther. July 26, 2011.
-
(2011)
Mol Ther
-
-
Kottke, T.1
Chester, J.2
Ilett, E.3
-
327
-
-
41949097523
-
Modeling of cancer virotherapy with recombinant measles viruses
-
Bajzer Z, Carr T, Josic K, et al. Modeling of cancer virotherapy with recombinant measles viruses. J Theor Biol. 2008;252:109-122.
-
(2008)
J Theor Biol
, vol.252
, pp. 109-122
-
-
Bajzer, Z.1
Carr, T.2
Josic, K.3
-
328
-
-
77951239900
-
Optimization of virotherapy for cancer
-
Biesecker M, Kimn JH, Lu H, et al. Optimization of virotherapy for cancer. Bull Math Biol. 2010;72:469-489.
-
(2010)
Bull Math Biol
, vol.72
, pp. 469-489
-
-
Biesecker, M.1
Kimn, J.H.2
Lu, H.3
-
329
-
-
30144435077
-
Mathematical modeling of cancer radiovirotherapy
-
Dingli D, Cascino MD, Josic K, et al. Mathematical modeling of cancer radiovirotherapy. Math Biosci. 2006;199:55-78.
-
(2006)
Math Biosci
, vol.199
, pp. 55-78
-
-
Dingli, D.1
Cascino, M.D.2
Josic, K.3
-
330
-
-
70449637667
-
Dynamics of multiple myeloma tumor therapy with a recombinant measles virus
-
Dingli D, Offord C, Myers R, et al. Dynamics of multiple myeloma tumor therapy with a recombinant measles virus. Cancer gene therapy. 2009;16:873-882.
-
(2009)
Cancer Gene Therapy
, vol.16
, pp. 873-882
-
-
Dingli, D.1
Offord, C.2
Myers, R.3
-
331
-
-
33644547005
-
Glioma virotherapy: Effects of innate immune suppression and increased viral replication capacity
-
Friedman A, Tian JP, Fulci G, et al. Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity. Cancer research. 2006;66:2314-2319.
-
(2006)
Cancer Research
, vol.66
, pp. 2314-2319
-
-
Friedman, A.1
Tian, J.P.2
Fulci, G.3
-
332
-
-
34248141607
-
Mathematical modeling of tumor therapy with oncolytic viruses: Effects of parametric heterogeneity on cell dynamics
-
Karev GP, Novozhilov AS, Koonin EV. Mathematical modeling of tumor therapy with oncolytic viruses: effects of parametric heterogeneity on cell dynamics. Biol Direct. 2006;1:30.
-
(2006)
Biol Direct
, vol.1
, pp. 30
-
-
Karev, G.P.1
Novozhilov, A.S.2
Koonin, E.V.3
-
333
-
-
33747458835
-
Mathematical modeling of tumor therapy with oncolytic viruses: Regimes with complete tumor elimination within the framework of deterministic models
-
Novozhilov AS, Berezovskaya FS, Koonin EV, Karev GP. Mathematical modeling of tumor therapy with oncolytic viruses: regimes with complete tumor elimination within the framework of deterministic models. Biol Direct. 2006;1:6.
-
(2006)
Biol Direct
, vol.1
, pp. 6
-
-
Novozhilov, A.S.1
Berezovskaya, F.S.2
Koonin, E.V.3
Karev, G.P.4
-
335
-
-
84862133299
-
Dynamics of melanoma tumor therapy with vesicular stomatitis virus: Explaining the variability in outcomes using mathematical modeling
-
September 15, Epub ahead of print
-
Rommelfanger DM, Offord CP, Dev J, et al. Dynamics of melanoma tumor therapy with vesicular stomatitis virus: explaining the variability in outcomes using mathematical modeling. Gene Ther. September 15, 2011. [Epub ahead of print.].
-
(2011)
Gene Ther
-
-
Rommelfanger, D.M.1
Offord, C.P.2
Dev, J.3
-
336
-
-
0037444281
-
Validation and analysis of a mathematical model of a replication-competent oncolytic virus for cancer treatment: Implications for virus design and delivery
-
Wein LM, Wu JT, Kirn DH. Validation and analysis of a mathematical model of a replication-competent oncolytic virus for cancer treatment: implications for virus design and delivery. Cancer Res. 2003;63:1317-1324.
-
(2003)
Cancer Res
, vol.63
, pp. 1317-1324
-
-
Wein, L.M.1
Wu, J.T.2
Kirn, D.H.3
-
337
-
-
63049110384
-
Towards predictive computational models of oncolytic virus therapy: Basis for experimental validation and model selection
-
Wodarz D, Komarova N. Towards predictive computational models of oncolytic virus therapy: basis for experimental validation and model selection. PloS One. 2009;4:e4271.
-
(2009)
PloS One
, vol.4
-
-
Wodarz, D.1
Komarova, N.2
-
338
-
-
0034905801
-
Modeling and analysis of a virus that replicates selectively in tumor cells
-
Wu JT, Byrne HM, Kirn DH, Wein LM. Modeling and analysis of a virus that replicates selectively in tumor cells. Bull Math Biol. 2001;63: 731-768.
-
(2001)
Bull Math Biol
, vol.63
, pp. 731-768
-
-
Wu, J.T.1
Byrne, H.M.2
Kirn, D.H.3
Wein, L.M.4
-
339
-
-
3042684543
-
Analysis of a three-way race between tumor growth, a replication-competent virus and an immune response
-
Wu JT, Kirn DH, Wein LM. Analysis of a three-way race between tumor growth, a replication-competent virus and an immune response. Bull Math Biol. 2004;66:605-625.
-
(2004)
Bull Math Biol
, vol.66
, pp. 605-625
-
-
Wu, J.T.1
Kirn, D.H.2
Wein, L.M.3
-
340
-
-
80855143747
-
Multi-stability and multi-instability phenomena in a mathematical model of tumor-immunevirus interactions
-
Eftimie R, Dushoff J, Bridle BW, et al. Multi-stability and multi-instability phenomena in a mathematical model of tumor-immunevirus interactions. Bull Math Biol. 2011;73:2932-2961.
-
(2011)
Bull Math Biol
, vol.73
, pp. 2932-2961
-
-
Eftimie, R.1
Dushoff, J.2
Bridle, B.W.3
|