Epigenetic Repression of miR-129-2 in Cancer

Liver International

Volumn 34, Issue 4, 2014, Pages 646-646

  He, Yong ^a   Huang, Cheng ^a   Zhang, Lei ^a   Li, Jun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE INHIBITOR; MICRORNA; MICRORNA 129 2; PROTEIN BCL 2; TRANSCRIPTION FACTOR SOX4; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CELL CYCLE ARREST; CELL PROLIFERATION; CELL STRAIN HEPG2; CHROMOSOME 11; COLORECTAL CANCER; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; ENDOMETRIUM CANCER; EPIGENETIC REPRESSION; GENE EXPRESSION; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MORTALITY; NEOPLASM; STOMACH CANCER;

CARCINOMA, HEPATOCELLULAR; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATITIS B; HUMANS; LIVER NEOPLASMS; MICRORNAS; SOXC TRANSCRIPTION FACTORS;

EID: 84895835190     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12367     Document Type: Article

References (8)

1. Chen X, Zhang L, Zhang T, et al. Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC. Liver Int 2013; 33: 476-86.
2. Baer C, Claus R, Plass C. Genome-wide epigenetic regulation of miRNAs in cancer. Cancer Res 2013; 73: 473-7.
3. Anwar SL, Albat C, Krech T, et al. Concordant hypermethylation of intergenic microRNA genes in human hepatocellular carcinoma as new diagnostic and prognostic marker. Int J Cancer 2013; 133: 660-70.
4. Lu CY, Lin KY, Tien MT, et al. Frequent DNA methylation of MiR-129-2 and its potential clinical implication in hepatocellular carcinoma. Genes Chromosom Cancer 2013; 52: 636-43.
5. Karaayvaz M, Zhai H, Ju J. miR-129 promotes apoptosis enhances chemosensitivity to 5-fluorouracil in colorectal cancer. Cell Death Dis 2013; 4: e659.
6. Bandres E, Agirre X, Bitarte N, et al. Epigenetic regulation of microRNA expression in colorectal cancer. Int J Cancer 2009; 125: 2737-43.
7. Shen R, Pan S, Qi S, et al. Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 in gastric cancer. Biochem Biophys Res Commun 2010; 394: 1047-52.
8. Huang YW, Liu JC, Deatherage DE, et al. Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 oncogene in endometrial cancer. Cancer Res 2009; 69: 9038-46.