Eculizumab therapy

Biology of Blood and Marrow Transplantation

Volumn 20, Issue 4, 2014, Pages 438-439

  Cataland, Spero R ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; ECULIZUMAB; COMPLEMENT INHIBITOR; COMPLEMENT MEMBRANE ATTACK COMPLEX; MONOCLONAL ANTIBODY;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; COMPLEMENT ACTIVATION; COMPLEMENT HEMOLYSIS TEST; CRITICALLY ILL PATIENT; DISEASE SEVERITY; DRUG EFFICACY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION ASSOCIATED THROMBOTIC MICROANGIOPATHY; HEMOLYTIC UREMIC SYNDROME; HETEROZYGOTE; HUMAN; HYPERTENSION; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY INJURY; MULTIPLE ORGAN FAILURE; NOTE; PATHOGENESIS; PATHOPHYSIOLOGY; PLASMAPHERESIS; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT RESPONSE; ARTICLE; CHILD; DRUG ANTAGONISM; IMMUNOLOGY; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PATHOLOGY;

ANTIBODIES, MONOCLONAL, HUMANIZED; CHILD; COMPLEMENT INACTIVATING AGENTS; COMPLEMENT MEMBRANE ATTACK COMPLEX; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMOGLOBINURIA, PAROXYSMAL; HEMOLYTIC-UREMIC SYNDROME; HUMANS; THROMBOTIC MICROANGIOPATHIES;

EID: 84895823908     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2014.02.006     Document Type: Note

References (4)

1. Jodele S., Fukuda T., Vinks A., et al. Eculizumab therapy in children with severe hematopoietic stem cell transplantation-associated thrombotic microangiopathy. Biol Blood Marrow Transplant 2014, 20:518-525.
2. Jodele S., Licht C., Goebel J., et al. Abnormalities in the alternative pathway of complement in children with hematopoietic stem cell transplant-associated thrombotic microangiopathy. Blood 2013, 122:2003-2007.
3. Legendre C.M., Licht C., Muus P., et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. New Engl J Med 2013, 368:2169-2181.
4. Zuber J., Fakhouri F., Roumenina L.T., et al. Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies. Nat Rev Nephrol 2012, 8:643-657.