Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Yang, Wen Ting ^a   Zheng, Peng Sheng ^a,b  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; CISPLATIN; KRUPPEL LIKE FACTOR 4;

ALLELE; ARTICLE; BISULFITE SEQUENCING; CANCER CELL; CANCER TISSUE; CARCINOGENESIS; CELL ASSAY; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CERVICAL CARCINOGENESIS; CHEMOSENSITIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENE SEQUENCE; GROWTH CURVE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KLF4 GENE; METHYLATION SPECIFIC POLYMERASE CHAIN REACTION; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CANCER; WESTERN BLOTTING;

AZACITIDINE; CARCINOGENESIS; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; PROTEIN BIOSYNTHESIS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; UTERINE CERVICAL NEOPLASMS;

EID: 84895818749     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088827     Document Type: Article

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