Index of alpha/theta ratio of the electroencephalogram: A new marker for Alzheimer's disease

Frontiers in Aging Neuroscience

Volumn 5, Issue OCT, 2013, Pages

  Schmidt, Magali T ^a   Kanda, Paulo A M ^a   Basile, Luis F H ^a,b   da Silva Lopes, Helder Frederico ^a   Baratho, Regina ^c   Demario, Jose L C ^c   Jorge, Mario S ^a   Nardi, Antonio E ^d,e   Machado, Sergio ^d,e   Ianof, Jéssica N ^a   Nitrini, Ricardo ^a   Anghinah, Renato ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSIDADE METODISTA DE SÃO PAULO   (Brazil)

^c PONTIFÍCIA UNIVERSIDADE CATÓLICA DE SÃO PAULO   (Brazil)

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^e National Institute of Translational Medicine (INCT TM)   (Brazil)

Author keywords

Alpha; Alzheimer's disease; EEG; Logistic regression; Theta

Indexed keywords

ADULT; AGED; ALPHA RHYTHM; ALZHEIMER DISEASE; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE MARKER; ELECTROENCEPHALOGRAM; ELECTROENCEPHALOGRAPH ELECTRODE; EYELID CLOSURE; FEMALE; HUMAN; MALE; MIDDLE AGED; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SPECTROSCOPY; THETA RHYTHM; VERY ELDERLY; WAKEFULNESS;

EID: 84895790562     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2013.00060     Document Type: Article

References (24)

1. Anderer, P., Saletu, B., Klöppel, B., Semlitsch, H. V., and Werner, H. (1994). Discrimination between demented patients and normals based on topographic EEG slow wave activity: comparison between z statistics, discriminant analysis and artificial neural network classifiers. Electrencephalogr Clin Neurophysiol 91, 108-117. doi:10.1016/0013-4694(94)90032-9.
2. Anghinah, R., Kanda, P. A. M., Jorge, M. S., Lima, E. E. P., Pascuzzi, L., and Melo, A. C. P. (2000). Estudo da coerência do eletroencefalograma para a banda de frequência alfa em indivíduos adultos normais e com demência do tipo Alzheimer. Arq Neuropsiquiatr 58, 272-275. doi:10.1590/S0004-282X2000000200011.
3. Babiloni, C., Binetti, G., Cassetta, E., Cerboneschi, D., Dal Forno, G., Del Percio, C., et al. (2004). Mapping distributed sources of cortical rhythms in mild Alzheimer's disease. A multicentric EEG study. Neuroimage 22, 57-67. doi:10.1016/j.neuroimage.2003.09.028.
4. Bennett, D. A., Schneider, J. A., Bienias, J. L., Evans, D. A., and Wilson, R. S. (2004). Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions. Neurology 23, 325-335.
5. Besthorn, C., Zerfass, R., Geiger-Kabisch, C., Sattel, H., Daniel, S., Schreiter-Gasser, U., et al. (1997). Discrimination of Alzheimer's disease and normal aging by EEG data. Electroencephalogr Clin Neurophysiol 103, 241-248. doi:10.1016/S0013-4694(97)96562-7.
6. Brenner, R. P., Reynolds, C. F III, and Ulrich, R. F. (1988). Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects. Electroencephalogr Clin Neurophysiol 69, 110. doi:10.1016/0013-4694(88)90206-4.
7. Cantero, J. L., Atienza, M., Gomez-Herrero, G., Cruz-Vadell, A., Gil-Neciga, E., Rodriguez-Romero, R., et al. (2009). Functional integrity of thalamocortical circuits differentiates normal aging from mild cognitive impairment. Hum Brain Mapp 30, 3944-3957. doi:10.1002/hbm.20819.
8. Caramelli, P., Herrera, E. Jr, and Nitrini, R. O. (1999). Mini-Exame do Estado Mental no diagnóstico de demência em idosos analfabeto. Arq Neuropsiquiatr 57, 57.
9. Caramelli, P., Teixeira, A. L., Buchpiguel, C. A., Lee, H. W., Livramento, J. A., Fernandez, L. L., et al. (2011). Diagnosis of Alzheimer disease's in Brazil-supplementary exams. Dement Neuropsychol 5, 167-177.
10. Cibils, D. (2002). Dementia and qEEG (Alzheimer' disease). Clin Neurophysiol 54, 289-294.
11. Claus, J. J., van Gool, W. A., Teunisse, S., Walstra, G. J. M., Kwa, V. I. H., Hijdra, A., et al. (1998). Predicting survival in patients with early Alzheimer's disease. Dement Geriatr Cogn Disord 9, 284-293. doi:10.1159/000017073.
12. Colom, L. V. (2006). Septal networks: relevance to theta rhythm, epilepsy and Alzheimer's disease. J Neurochem 96, 609-623. doi:10.1111/j.1471-4159.2005.03630.x.
13. Davies, P., and Maloney, A. J. (1976). Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 2, 1403. doi:10.1016/S0140-6736(76)91936-X.
14. Kukull, W. A., and Bowen, J. D. (2002). Dementia epidemiology. Med Clin North Am 86, 573-590. doi:10.1016/S0025-7125(02)00010-X.
15. Lizio, R., Vecchio, F., Frisoni, G. B., Ferri, R., Rodriguez, G., and Babiloni, C. (2011). Electroencephalographic rhythms in Alzheimer's disease. Int J Alzheimers Dis 2011, 927573. doi:10.4061/2011/927573.
16. Llinás, R. R., Ribary, U., Jeanmonod, D., Kronberg, E., and Mitra, P. P. (1999). Thalamocortical dysrhythmia: a neurological and neuropsychiatric syndrome characterized by magnetoencephalography. Proc Natl Acad Sci U S A 96, 15222-15227. doi:10.1073/pnas.96.26.15222.
17. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., and Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34, 939-944. doi:10.1212/WNL.34.7.939.
18. Morris, J. C. (1993). The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 43, 2412-2414. doi:10.1212/WNL.43.11.2412-a.
19. Mufson, E., Counts, S. E., Perez, S. E., and Ginsberg, S. (2008). Cholinergic system during the progression of Alzheimer's disease: therapeutic implications. Expert Rev Neurother 8, 1703-1718. doi:10.1586/14737175.8.11.1703.
20. Nitrini, R., Caramelli, P., Bottino, C. M. C., Damasceno, B. P., Brucki, S. M. D., and Anghinah, R. (2005). Diagnóstico de doença de Alzheimer no Brasil: critérios diagnósticos e exames complementares. Recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia. Arq Neuropsiquiatr 63, 713-719. doi:10.1590/S0004-282X2005000400034.
21. Ordinance of The Health Care Secretariat/Brazilian Ministry of Health. No. 843, November 6, 2002-Article 10 Approve the Protocol Clinical Guideline-Dementia in Alzheimer's disease-rivastigmine, galantamine and donepezil-as attachment of this ordinance. Brazil.
22. Reis IN, Fonseca LC. Reatividade à abertura dos olhos ao eletroencefalograma na doença de Alzheimer: relação com aspectos cognitivos. Annals of the 15th Meeting of Scientific Initiation of Pontifical Catholic University of Campinas. PUC-Campinas (2010).
23. Schliebs, R., and Arendt, T. (2011). The cholinergic system in aging and neuronal degeneration. Behav Brain Res 221, 555-563. doi:10.1016/j.bbr.2010.11.058.
24. Watanabe, H., Koike, Y., Takahashi, A., and Iguchi, H. (1993). EEG changes during mental calculation, reverse recitation and association exercises in patients with DA. Intern Med 3, 87-93. doi:10.2169/internalmedicine.32.87.