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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 6, 2014, Pages 1496-1501

Discovery of novel bis-oxazolidinone compounds as potential potent and selective antitubercular agents

(8) Ang, Wei a,b Ye, Weiwei a Sang, Zitai a Liu, Yuanyuan a Yang, Tao a Deng, Yong b Luo, Youfu a Wei, Yuquan a

a SICHUAN UNIVERSITY (China)

b SICHUAN UNIVERSITY (China)

Author keywords

Antitubercular; Bis oxazolidinone; Selectivity; Tuberculosis; Vero cells

Indexed keywords

CARBONYL DERIVATIVE; CARBONYLDIIMIDAZOLE; IMIDAZOLE DERIVATIVE; LINEZOLID; OXAZOLIDINONE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; IC 50; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PSEUDOMONAS AERUGINOSA; REACTION ANALYSIS; RING CLOSING METATHESIS; STAPHYLOCOCCUS AUREUS;

ESCHERICHIA COLI; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MYCOBACTERIUM SMEGMATIS; NEGIBACTERIA; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

ANTITUBERCULAR; BIS-OXAZOLIDINONE; SELECTIVITY; TUBERCULOSIS; VERO CELLS;

ANIMALS; ANTITUBERCULAR AGENTS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DRUG EVALUATION, PRECLINICAL; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; OXAZOLIDINONES; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

EID: 84895790008 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.02.025 Document Type: Article

Times cited : (19)

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