68Ga-DOTATOC PET-CT in the localization of source of ectopic ACTH in patients with ectopic ACTH-dependent Cushing's syndrome

Clinical Imaging

Volumn 38, Issue 2, 2014, Pages 208-211

  Venkitaraman, Balasubramanian ^a   Karunanithi, Sellam ^a   Kumar, Arvind ^a   Bal, Chandrasekhar ^a   Ammini, Ariachery C ^a   Kumar, Rakesh ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Ectopic ACTH dependent Cushing's syndrome; Neuroendocrine tumors; PET CT

Indexed keywords

GALLIUM; POSITRON EMISSION TOMOGRAPHY; TUMORS;

ECTOPIC ACTH-DEPENDENT CUSHING'S SYNDROME; LOCALIZATION OF SOURCES; NEUROENDOCRINE TUMORS; PET-CT; POSITRON EMISSION; STRUCTURAL IMAGING; SURGICAL RESECTION;

COMPUTERIZED TOMOGRAPHY;

CORTICOTROPIN; DOTATOC GA 68; FLUORODEOXYGLUCOSE F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; DRUG DERIVATIVE; GA(III) DOTATOC; GA(III)-DOTATOC; OCTREOTIDE; ORGANOMETALLIC COMPOUND;

ADRENALECTOMY; ADULT; ANAMNESIS; ARTICLE; CARCINOID; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTRAST ENHANCEMENT; CUSHING DISEASE; DISEASE COURSE; DISEASE DURATION; DRUG UPTAKE; FATIGUE; FEMALE; FOLLOW UP; GLYCEMIC CONTROL; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; IMAGE QUALITY; LAPAROSCOPIC SURGERY; LOBECTOMY; LUNG NODULE; LYMPHADENOPATHY; MALE; MEDIASTINUM LYMPH NODE; PRIORITY JOURNAL; REPEAT PROCEDURE; SKIN PIGMENTATION; THORACOTOMY; THORAX RADIOGRAPHY; TREATMENT RESPONSE; WEIGHT GAIN; (68)GA-DOTATOC; COMPUTER ASSISTED TOMOGRAPHY; CUSHING SYNDROME; ECTOPIC ACTH-DEPENDENT CUSHING'S SYNDROME; ECTOPIC CORTICOTROPIN PRODUCTION; METABOLISM; MIDDLE AGED; MULTIMODAL IMAGING; NEUROENDOCRINE TUMOR; PET-CT; POSITRON EMISSION TOMOGRAPHY; SCINTISCANNING; TREATMENT OUTCOME;

(68)GA-DOTATOC; ECTOPIC ACTH-DEPENDENT CUSHING'S SYNDROME; NEUROENDOCRINE TUMORS; PET-CT;

ACTH SYNDROME, ECTOPIC; ADRENOCORTICOTROPIC HORMONE; ADULT; CUSHING SYNDROME; FEMALE; HUMANS; MIDDLE AGED; MULTIMODAL IMAGING; NEUROENDOCRINE TUMORS; OCTREOTIDE; ORGANOMETALLIC COMPOUNDS; POSITRON-EMISSION TOMOGRAPHY; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 84895783351     PISSN: 08997071     EISSN: 18734499     Source Type: Journal    
DOI: 10.1016/j.clinimag.2013.10.007     Document Type: Article

References (14)

1. Ejaz S, Vassilopoulou-Sellin R, Busaidy NL, Hu MI, Waguespack SG, Jimenez C, Ying AK, Cabanillas M, Abbara M, Habra MA Cushing syndrome secondary to ectopic adrenocorticotropic hormone secretion: the University of Texas MD Anderson Cancer Center Experience. Cancer 2011, 117:4381-4389.
2. Ilias I, Torpy DJ, Pacak K, Mullen N, Wesley RA, Nieman LK Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of Health. J Clin Endocrinol Metab 2005, 90:4955-4962.
3. Lindsay JR, Nieman LK Differential diagnosis and imaging in Cushing's syndrome. Endocrinol Metab Clin North Am 2005, 34:403-421.
4. Aniszewski JP, Young WF, Thompson GB, Grant CS, van Heerden JA Cushing syndrome due to ectopic adrenocorticotropic hormone secretion. World J Surg 2001, 25:934-940.
5. 18F-FDG. Cancer 2008, 112:2447-2455.
6. Jindal T, Kumar A, Venkitaraman B, Dutta R, Kumar R Role of (68)Ga-DOTATOC PET/CT in the evaluation of primary pulmonary carcinoids. Korean J Intern Med 2010, 25:386-391.
7. Wajchenberg BL, Mendonca BB, Liberman B, Pereira MA, Carneiro PC, Wakamatsu A, Kirschner MA Ectopic adrenocorticotropic hormone syndrome. Endocrinol Rev 1994, 15:752-787.
8. Wajchenberg BL, Mendonça B, Liberman B, Adelaide M, Pereira A, Kirschner MA Ectopic ACTH syndrome. J Steroid Biochem Mol Biol 1995, 53:139-151.
9. Oldfield EH, Doppman JL, Nieman LK, Chrousos GP, Miller DL, Katz DA, Cutler GB, Loriaux DL Petrosal sinus sampling with and without corticotropin-releasing hormone for the differential diagnosis of Cushing's syndrome. N Engl J Med 1991, 325:897-905.
10. Jindal T, Kumar A, Venkitaraman B, Meena M, Kumar R, Malhotra A, Dutta R Evaluation of the role of [18F]FDG-PET/CT and [68Ga]DOTATOC-PET/CT in differentiating typical and atypical pulmonary carcinoids. Cancer Imaging 2011, 11:70-75.
11. Reubi JC, Laissue J, Krenning E, Lamberts SW Somatostatin receptors in human cancer: incidence, characteristics, functional correlates and clinical implications. J Steroid Biochem Mol Biol 1992, 43:27-35.
12. Tabarin A, Valli N, Chanson P, Bachelot Y, Rohmer V, Bex-Bachellerie V, Catargi B, Roger P, Laurent F Usefulness of somatostatin receptor scintigraphy in patients with occult ectopic adrenocorticotropin syndrome. J Clin Endocrinol Metab 1999, 84:1193-1202.
13. 68Ga-DOTA-NOC: a new PET tracer for evaluating patients with bronchial carcinoid. Nucl Med Commun 2009, 30:281-286.
14. 18F-DOPA PET for the detection of gastro-entero-pancreatic and lung neuro-endocrine tumours. Eur J Nucl Med Mol Imaging 2008, 35:1431-1438.