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Volumn 9, Issue 2, 2014, Pages

Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYTOSKELETON PROTEIN; DYSTROPHIN; EPITOPE; MONOCLONAL ANTIBODY; SYNAPTOTAGMIN I;

EID: 84895769321     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088280     Document Type: Article
Times cited : (18)

References (43)
  • 2
    • 12344259558 scopus 로고    scopus 로고
    • 2004 William Allan award address. Cloning of the DMD gene
    • Kunkel LM (2005) 2004 William Allan award address. cloning of the DMD gene. Am J Hum Genet 76: 205-214.
    • (2005) Am J Hum Genet , vol.76 , pp. 205-214
    • Kunkel, L.M.1
  • 3
    • 0023614271 scopus 로고
    • Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals
    • DOI 10.1016/0092-8674(87)90504-6
    • Koenig M, Hoffman EP, Bertelson CJ, Monaco AP, Feener C, et al. (1987) Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals. Cell 50: 509-517. (Pubitemid 18098338)
    • (1987) Cell , vol.50 , Issue.3 , pp. 509-517
    • Koening, M.1    Hoffman, E.P.2    Bertelson, C.J.3    Monaco, A.P.4    Feener, C.5    Kunkel, L.M.6
  • 4
    • 0023614188 scopus 로고
    • Dystrophin: The protein product of the Duchenne muscular dystrophy locus
    • Hoffman EP, Brown RH Jr, Kunkel LM (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51: 919-928.
    • (1987) Cell , vol.51 , pp. 919-928
    • Hoffman, E.P.1    Brown Jr., R.H.2    Kunkel, L.M.3
  • 6
    • 0023904860 scopus 로고
    • The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein
    • Koenig M, Monaco AP, Kunkel LM (1988) The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein. Cell 53: 219-526.
    • (1988) Cell , vol.53 , pp. 219-526
    • Koenig, M.1    Monaco, A.P.2    Kunkel, L.M.3
  • 7
    • 0025217703 scopus 로고
    • Detailed analysis of the repeat domain of dystrophin reveals four potential hinge segments that may confer flexibility
    • Koenig M, Kunkel LM (1990) Detailed analysis of the repeat domain of dystrophin reveals four potential hinge segments that may confer flexibility. J Biol Chem 265: 4560-4566.
    • (1990) J Biol Chem , vol.265 , pp. 4560-4566
    • Koenig, M.1    Kunkel, L.M.2
  • 8
    • 0024300196 scopus 로고
    • Immunoelectron microscopic localization of dystrophin in myofibres
    • Watkins SC, Hoffman EP, Slayter HS, Kunkel LM (1988) Immunoelectron microscopic localization of dystrophin in myofibres. Nature 333: 863-866.
    • (1988) Nature , vol.333 , pp. 863-866
    • Watkins, S.C.1    Hoffman, E.P.2    Slayter, H.S.3    Kunkel, L.M.4
  • 9
    • 0036087342 scopus 로고    scopus 로고
    • Function and genetics of dystrophin and dystrophin-related proteins in muscle
    • Blake DJ, Weir A, Newey SE, Davies KE (2002) Function and genetics of dystrophin and dystrophin-related proteins in muscle. Physiol Rev 82: 291-329. (Pubitemid 34654455)
    • (2002) Physiological Reviews , vol.82 , Issue.2 , pp. 291-329
    • Blake, D.J.1    Weir, A.2    Newey, S.E.3    Davies, K.E.4
  • 10
    • 0036839039 scopus 로고    scopus 로고
    • Molecular pathophysiology of myofiber injury in deficiencies of the dystrophin-glycoprotein complex
    • Petrof BJ (2002) Molecular pathophysiology of myofiber injury in deficiencies of the dystrophin-glycoprotein complex. Am J Phys Med Rehabil 81: S162-174.
    • (2002) Am J Phys Med Rehabil , vol.81
    • Petrof, B.J.1
  • 12
    • 0023718118 scopus 로고
    • An explanation for the phenotypic differences between patients bearing partial deletions of the DMD locus
    • Monaco AP, Bertelson CJ, Liechti-Gallati S, Moser H, Kunkel LM (1988) An explanation for the phenotypic differences between patients bearing partial deletions of the DMD locus. Genomics 2: 90-95.
    • (1988) Genomics , vol.2 , pp. 90-95
    • Monaco, A.P.1    Bertelson, C.J.2    Liechti-Gallati, S.3    Moser, H.4    Kunkel, L.M.5
  • 13
    • 0023906647 scopus 로고
    • Characterization of dystrophin in muscle-biopsy specimens from patients with Duchenne's or Becker's muscular dystrophy
    • Hoffman EP, Fischbeck KH, Brown RH, Johnson M, Medori R, et al (1988) Characterization of dystrophin in muscle-biopsy specimens from patients with Duchenne's or Becker's muscular dystrophy. N Engl J Med 318: 1363-1368.
    • (1988) N Engl J Med , vol.318 , pp. 1363-1368
    • Hoffman, E.P.1    Fischbeck, K.H.2    Brown, R.H.3    Johnson, M.4    Medori, R.5
  • 15
    • 79960058937 scopus 로고    scopus 로고
    • Monitoring duchenne muscular dystrophy gene therapy with epitope-specific monoclonal antibodies
    • Morris GE, Man NT, Sewry CA (2011) Monitoring duchenne muscular dystrophy gene therapy with epitope-specific monoclonal antibodies. Methods Mol Biol 709: 39-61.
    • (2011) Methods Mol Biol , vol.709 , pp. 39-61
    • Morris, G.E.1    Man, N.T.2    Sewry, C.A.3
  • 17
    • 0027365063 scopus 로고
    • Use of epitope libraries to identify exon-specific monoclonal antibodies for characterization of altered dystrophins in muscular dystrophy
    • Nguyen TM, Morris GE (1993) Use of epitope libraries to identify exon-specific monoclonal antibodies for characterization of altered dystrophins in muscular dystrophy. Am J Hum Genet 52: 1057-1066.
    • (1993) Am J Hum Genet , vol.52 , pp. 1057-1066
    • Nguyen, T.M.1    Morris, G.E.2
  • 18
    • 0026732709 scopus 로고
    • Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues
    • Hugnot JP, Gilgenkrantz H, Vincent N, Chafey P, Morris GE, et al. (1992) Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues. Proc Natl Acad Sci U S A 89: 7506-7510.
    • (1992) Proc Natl Acad Sci U S a , vol.89 , pp. 7506-7510
    • Hugnot, J.P.1    Gilgenkrantz, H.2    Vincent, N.3    Chafey, P.4    Morris, G.E.5
  • 19
    • 0026653859 scopus 로고
    • A 71-kilodalton protein is a major product of the Duchenne muscular dystrophy gene in brain and other nonmuscle tissues
    • Lederfein D, Levy Z, Augier N, Augier N, Mornet D, et al. (1992) A 71-kilodalton protein is a major product of the Duchenne muscular dystrophy gene in brain and other nonmuscle tissues. Proc Natl Acad Sci U S A 89: 5346-5350.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 5346-5350
    • Lederfein, D.1    Levy, Z.2    Augier, N.3    Augier, N.4    Mornet, D.5
  • 20
    • 0028910144 scopus 로고
    • Characterization of revertant muscle fibers in Duchenne muscular dystrophy, using exon-specific monoclonal antibodies against dystrophin
    • Thanh LT, Nguyen TM, Helliwell TR, Morris GE (1995) Characterization of revertant muscle fibers in Duchenne muscular dystrophy, using exon-specific monoclonal antibodies against dystrophin. Am J Hum Genet 56: 725-731.
    • (1995) Am J Hum Genet , vol.56 , pp. 725-731
    • Thanh, L.T.1    Nguyen, T.M.2    Helliwell, T.R.3    Morris, G.E.4
  • 22
    • 0025256855 scopus 로고
    • Monoclonal antibodies against defined regions of the muscular dystrophy protein, dystrophin
    • Nguyen thi M, Cartwright AJ, Morris GE, Love DR, Bloomfield JF, et al. (1990) Monoclonal antibodies against defined regions of the muscular dystrophy protein, dystrophin. FEBS Lett 262: 237-240.
    • (1990) FEBS Lett , vol.262 , pp. 237-240
    • Nguyen Thi, M.1    Cartwright, A.J.2    Morris, G.E.3    Love, D.R.4    Bloomfield, J.F.5
  • 23
    • 84862018387 scopus 로고    scopus 로고
    • Duchenne muscular dystrophy gene therapy: Lost in translation?
    • Duan D (2011) Duchenne muscular dystrophy gene therapy: lost in translation? Resarch and Report in Biology 2: 31-42.
    • (2011) Resarch and Report in Biology , vol.2 , pp. 31-42
    • Duan, D.1
  • 24
    • 79960089426 scopus 로고    scopus 로고
    • Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs
    • Fine DM, Shin JH, Yue Y, Volkmann D, Leach SB, et al. (2011) Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs. Neuromuscul Disord 21: 453-461.
    • (2011) Neuromuscul Disord , vol.21 , pp. 453-461
    • Fine, D.M.1    Shin, J.H.2    Yue, Y.3    Volkmann, D.4    Leach, S.B.5
  • 25
    • 79551596262 scopus 로고    scopus 로고
    • An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed
    • Smith BF, Yue Y, Woods PR, Kornegay JN, Shin JH, et al. (2011) An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed. Lab Invest 91: 216-231.
    • (2011) Lab Invest , vol.91 , pp. 216-231
    • Smith, B.F.1    Yue, Y.2    Woods, P.R.3    Kornegay, J.N.4    Shin, J.H.5
  • 26
    • 84866039008 scopus 로고    scopus 로고
    • Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy
    • Yang HT, Shin JH, Hakim CH, Pan X, Terjung RL, et al. (2012) Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy. PLoS ONE 7: e44438.
    • (2012) PLoS ONE , vol.7
    • Yang, H.T.1    Shin, J.H.2    Hakim, C.H.3    Pan, X.4    Terjung, R.L.5
  • 27
    • 84875469221 scopus 로고    scopus 로고
    • Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring
    • Shin JH, Greer B, Hakim CH, Zhou Z, Chung YC, et al. (2013) Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring. PLoS One 8: e59875.
    • (2013) PLoS One , vol.8
    • Shin, J.H.1    Greer, B.2    Hakim, C.H.3    Zhou, Z.4    Chung, Y.C.5
  • 28
    • 0030330044 scopus 로고    scopus 로고
    • Production of panels of monoclonal antibodies by the hybridoma method
    • Nguyen TM, Morris GE (1996) Production of panels of monoclonal antibodies by the hybridoma method. Methods Mol Biol 66: 377-389.
    • (1996) Methods Mol Biol , vol.66 , pp. 377-389
    • Nguyen, T.M.1    Morris, G.E.2
  • 30
    • 0031826294 scopus 로고    scopus 로고
    • A new blocking method for application of murine monoclonal antibody to mouse tissue sections
    • Lu QL, Partridge TA (1998) A new blocking method for application of murine monoclonal antibody to mouse tissue sections. J Histochem Cytochem 46: 977-984.
    • (1998) J Histochem Cytochem , vol.46 , pp. 977-984
    • Lu, Q.L.1    Partridge, T.A.2
  • 32
    • 84881426347 scopus 로고    scopus 로고
    • Finding the right antibody for the job
    • Marx V (2013) Finding the right antibody for the job. Nature Methods 10: 703-707.
    • (2013) Nature Methods , vol.10 , pp. 703-707
    • Marx, V.1
  • 33
    • 65649111197 scopus 로고    scopus 로고
    • Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy
    • Lai Y, Thomas GD, Yue Y, Yang HT, Li D, et al. (2009) Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy. J Clin Invest 119: 624-635.
    • (2009) J Clin Invest , vol.119 , pp. 624-635
    • Lai, Y.1    Thomas, G.D.2    Yue, Y.3    Yang, H.T.4    Li, D.5
  • 34
    • 84872175513 scopus 로고    scopus 로고
    • alpha2 and alpha3 helices of dystrophin R16 and R17 frame a microdomain in the alpha1 helix of dystrophin R17 for neuronal NOS binding
    • Lai Y, Zhao J, Yue Y, Duan D (2013) alpha2 and alpha3 helices of dystrophin R16 and R17 frame a microdomain in the alpha1 helix of dystrophin R17 for neuronal NOS binding. Proc Natl Acad Sci U S A 110: 525-530.
    • (2013) Proc Natl Acad Sci U S a , vol.110 , pp. 525-530
    • Lai, Y.1    Zhao, J.2    Yue, Y.3    Duan, D.4
  • 36
    • 41949122156 scopus 로고    scopus 로고
    • Generation and characterization of transgenic mice with the full-length human DMD gene
    • 't Hoen PA, de Meijer EJ, Boer JM, Vossen RH, Turk R, et al. (2008) Generation and characterization of transgenic mice with the full-length human DMD gene. J Biol Chem 283: 5899-5907.
    • (2008) J Biol Chem , vol.283 , pp. 5899-5907
    • 'T Hoen, P.A.1    De Meijer, E.J.2    Boer, J.M.3    Vossen, R.H.4    Turk, R.5
  • 37
    • 0032483088 scopus 로고    scopus 로고
    • An epitope structure for the C-terminal domain of dystrophin and utrophin
    • DOI 10.1021/bi9805137, PII S0006296098005133
    • Morris GE, Sedgwick SG, Ellis JM, Pereboev A, Chamberlain JS, et al. (1998) An epitope structure for the C-terminal domain of dystrophin and utrophin. Biochemistry 37: 11117-11127. (Pubitemid 28368939)
    • (1998) Biochemistry , vol.37 , Issue.31 , pp. 11117-11127
    • Morris, G.E.1    Sedgwick, S.G.2    Ellis, J.M.3    Pereboev, A.4    Chamberlain, J.S.5    Man, N.T.6
  • 38
    • 0026472405 scopus 로고
    • Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections
    • Nguyen TM, Ginjaar IB, van Ommen GJ, Morris GE (1992) Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections. Biochem J 288 (Pt 2): 663-668.
    • (1992) Biochem J , vol.288 , Issue.PART 2 , pp. 663-668
    • Nguyen, T.M.1    Ginjaar, I.B.2    Van Ommen, G.J.3    Morris, G.E.4
  • 41
    • 0026355180 scopus 로고
    • Localization of the DMDL gene-encoded dystrophin-related protein using a panel of nineteen monoclonal antibodies: Presence at neuromuscular junctions, in the sarcolemma of dystrophic skeletal muscle, in vascular and other smooth muscles, and in proliferating brain cell lines
    • Nguyen TM, Ellis JM, Love DR, Davies KE, Gatter KC, et al. (1991) Localization of the DMDL gene-encoded dystrophin-related protein using a panel of nineteen monoclonal antibodies: presence at neuromuscular junctions, in the sarcolemma of dystrophic skeletal muscle, in vascular and other smooth muscles, and in proliferating brain cell lines. J Cell Biol 115: 1695-1700. (Pubitemid 21910009)
    • (1991) Journal of Cell Biology , vol.115 , Issue.6 , pp. 1695-1700
    • Nguyen, T.M.1    Ellis, J.M.2    Love, D.R.3    Davies, K.E.4    Gatter, K.C.5    Dickson, G.6    Morris, G.E.7
  • 42
    • 77953550591 scopus 로고    scopus 로고
    • Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin
    • Li D, Bareja A, Judge L, Yue Y, Lai Y, et al. (2010) Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin. J Cell Sci 123: 2008-2013.
    • (2010) J Cell Sci , vol.123 , pp. 2008-2013
    • Li, D.1    Bareja, A.2    Judge, L.3    Yue, Y.4    Lai, Y.5
  • 43
    • 0030796632 scopus 로고    scopus 로고
    • Controversial muscular dystrophy therapy goes to court
    • Birmingham K (1997) Controversial muscular dystrophy therapy goes to court. Nature medicine 3: 1058.
    • (1997) Nature Medicine , vol.3 , pp. 1058
    • Birmingham, K.1


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