No evidence for a role of rare CYP27B1 variants in Austrian multiple sclerosis patients

Multiple Sclerosis Journal

Volumn 20, Issue 3, 2014, Pages 391-392

  Reinthaler, Eva ^a   MacHetanz, Gerrit ^a   Hotzy, Christoph ^a   Reindl, Markus ^b   Fazekas, Franz ^c   Kristoferitsch, Wolfgang ^d   Berger, Thomas ^b   Schmied, Christiane ^a   Zimprich, Alexander ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

^d Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

AUSTRIA; CYP27B1 GENE; DISEASE ASSOCIATION; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; LETTER; MULTIPLE SCLEROSIS; VITAMIN D DEFICIENCY; ADULT; ALLELE; COHORT ANALYSIS; CONTROLLED STUDY; EXON; FEMALE; GENE FREQUENCY; GENETIC RISK; GENOTYPE; MAJOR CLINICAL STUDY; MALE;

25-HYDROXYVITAMIN D3 1-ALPHA-HYDROXYLASE; ALLELES; AUSTRIA; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MULTIPLE SCLEROSIS;

VITAMIN D;

EID: 84895758148     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458513498130     Document Type: Letter

References (5)

1. Simon KC, Munger KL, Ascherio A. Vitamin D and multiple sclerosis: Epidemiology, immunology and genetics. Curr Opin Neurol. 2012 ; 25: 246-251
2. Ramagopalan SV, Dyment DA, Cader MZ, et al. Rare variants in the CYP27B1 gene are associated with multiple sclerosis. Ann Neurol. 2011 ; 70: 881-886
3. Henry HL. Regulation of vitamin D metabolism. Best Pract Res Clin Endocrinol Metab. 2011 ; 25: 531-541
4. Wang JT, Lin CJ, Burridge SM, et al. Genetics of vitamin D 1alpha-hydroxylase deficiency in 17 families. Am J Hum Genet. 1998 ; 63: 1694-1702 (Pubitemid 30415732)
5. Barizzone N, Pauwels I, Luciano B, et al. No evidence for a role of rare CYP27B1 functional variations in multiple sclerosis. Ann Neurol. 2012 ;: 1-5