메뉴 건너뛰기




Volumn 99, Issue 3, 2014, Pages 437-447

Measurement of adherence to BCR-ABL inhibitor therapy in chronic myeloid leukemia: Current situation and future challenges

Author keywords

[No Author keywords available]

Indexed keywords

DASATINIB; IMATINIB; NILOTINIB; ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; PROTEIN KINASE INHIBITOR;

EID: 84895746438     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.082511     Document Type: Review
Times cited : (66)

References (83)
  • 1
    • 77954328319 scopus 로고    scopus 로고
    • Chronic myeloid leukaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • ESMO Guidelines Working Group
    • Baccarani M, Dreyling M, ESMO Guidelines Working Group. Chronic myeloid leukaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010;21(Suppl. 5):v165-7.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5
    • Baccarani, M.1    Dreyling, M.2
  • 2
    • 84895752784 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network: NCCN clinical practice guidelines in oncology (NCCN Guidelines™)
    • [Internet], [accessed 2011]. Available from
    • NCCN. org [Internet]. National Comprehensive Cancer Network: NCCN clinical practice guidelines in oncology (NCCN Guidelines™). Chronic myelogenous leukemia. Version 2.2011 [accessed 2011]. Available from: http://www.nccn.org/professionals/physician_ gls/pdf/cml.pdf.
    • Chronic myelogenous leukemia. Version 2.2011
  • 3
    • 0033614446 scopus 로고    scopus 로고
    • Chronic myeloid leukemia
    • Sawyers CL. Chronic myeloid leukemia. N Engl J Med. 1999;340(17):1330-40.
    • (1999) N Engl J Med , vol.340 , Issue.17 , pp. 1330-1340
    • Sawyers, C.L.1
  • 4
    • 33846828641 scopus 로고    scopus 로고
    • The biology of chronic myelogenous leukemia: Implications for imatinib therapy
    • Alvarez RH, Kantarjian H, Cortes JE. The biology of chronic myelogenous leukemia: implications for imatinib therapy. Semin Hematol. 2007;44(1 suppl. 1):S4-14.
    • (2007) Semin Hematol , vol.44 , Issue.1 SUPPL. 1
    • Alvarez, R.H.1    Kantarjian, H.2    Cortes, J.E.3
  • 5
    • 73349122639 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet
    • Baccarani M, Cortes J, Pane F, Niederwieser D, Saglio G, Apperley J, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet. J Clin Oncol. 2009;27(35):6041-51.
    • (2009) J Clin Oncol , vol.27 , Issue.35 , pp. 6041-6051
    • Baccarani, M.1    Cortes, J.2    Pane, F.3    Niederwieser, D.4    Saglio, G.5    Apperley, J.6
  • 9
    • 77953725855 scopus 로고    scopus 로고
    • Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
    • Kantarjian H, Shah NP, Hochhaus A, Cortes J, Shah S, Ayala M, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2010;362(24):2260-70.
    • (2010) N Engl J Med , vol.362 , Issue.24 , pp. 2260-2270
    • Kantarjian, H.1    Shah, N.P.2    Hochhaus, A.3    Cortes, J.4    Shah, S.5    Ayala, M.6
  • 10
  • 11
    • 84871215155 scopus 로고    scopus 로고
    • Dasatinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): DASISION 3-year follow-up
    • Abstract 6504
    • Hochhaus A, Shah NP, Cortes JE, Baccarani M, Bradley-Garelik MB, Dejardin D, et al. Dasatinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): DASISION 3-year follow-up. J Clin Oncol. 2012;30(suppl.):Abstract 6504.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Hochhaus, A.1    Shah, N.P.2    Cortes, J.E.3    Baccarani, M.4    Bradley-Garelik, M.B.5    Dejardin, D.6
  • 12
    • 84871221765 scopus 로고    scopus 로고
    • Nilotinib versus imatinib in patients (pts) with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): ENESTnd 3-year (yr) follow-up (f/u)
    • Abstract 6509
    • Kantarjian H, Flinn IW, Goldberg S, Bunworasate U, Zanichelli MA, Nakamae H, et al. Nilotinib versus imatinib in patients (pts) with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): ENESTnd 3-year (yr) follow-up (f/u). J Clin Oncol. 2012;30(suppl.)Abstract 6509.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Kantarjian, H.1    Flinn, I.W.2    Goldberg, S.3    Bunworasate, U.4    Zanichelli, M.A.5    Nakamae, H.6
  • 13
    • 84855895068 scopus 로고    scopus 로고
    • Adherence to medications: Insights arising from studies on the unreliable link between prescribed and actual drug dosing histories
    • Blaschke TF, Osterberg L, Vrijens B, Urquhart J. Adherence to medications: insights arising from studies on the unreliable link between prescribed and actual drug dosing histories. Ann Rev Pharmacol Toxicol. 2012;52:275-301.
    • (2012) Ann Rev Pharmacol Toxicol , vol.52 , pp. 275-301
    • Blaschke, T.F.1    Osterberg, L.2    Vrijens, B.3    Urquhart, J.4
  • 14
    • 67049087117 scopus 로고    scopus 로고
    • Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: The ADAGIO study
    • Noens L, van Lierde MA, De Bock R, Verhoef G, Zachée P, Berneman Z, et al. Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study. Blood. 2009;113(22): 5401-11.
    • (2009) Blood , vol.113 , Issue.22 , pp. 5401-5411
    • Noens, L.1    van Lierde, M.A.2    De Bock, R.3    Verhoef, G.4    Zachée, P.5    Berneman, Z.6
  • 15
    • 77952467377 scopus 로고    scopus 로고
    • Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib
    • Marin D, Bazeos A, Mahon FX, Eliasson L, Milojkovic D, Buaet M, et al. Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib. J Clin Oncol. 2010;28(14):2381-8.
    • (2010) J Clin Oncol , vol.28 , Issue.14 , pp. 2381-2388
    • Marin, D.1    Bazeos, A.2    Mahon, F.X.3    Eliasson, L.4    Milojkovic, D.5    Buaet, M.6
  • 16
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and metaanalyses: The PRISMA statement
    • PRISMA Group
    • Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and metaanalyses: the PRISMA statement. BMJ. 2009;339:332-6.
    • (2009) BMJ , vol.339 , pp. 332-336
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 18
    • 10244257546 scopus 로고    scopus 로고
    • Imatinib and pegylated human recombinant interferon-alpha2b in early chronicphase chronic myeloid leukemia
    • Baccarani M, Martinelli G, Rosti G, Trabacchi E, Testoni N, Bassi S, et al. Imatinib and pegylated human recombinant interferon-alpha2b in early chronicphase chronic myeloid leukemia. Blood. 2004;104(13):4245-51.
    • (2004) Blood , vol.104 , Issue.13 , pp. 4245-4251
    • Baccarani, M.1    Martinelli, G.2    Rosti, G.3    Trabacchi, E.4    Testoni, N.5    Bassi, S.6
  • 19
    • 78649631804 scopus 로고    scopus 로고
    • Imatinib treatment in chronic myelogenous leukemia: What have we learned so far?
    • Breccia M, Efficace F, Alimena G. Imatinib treatment in chronic myelogenous leukemia: What have we learned so far? Cancer Lett. 2011;300(2):115-121.
    • (2011) Cancer Lett , vol.300 , Issue.2 , pp. 115-121
    • Breccia, M.1    Efficace, F.2    Alimena, G.3
  • 20
    • 34249782019 scopus 로고    scopus 로고
    • Treatment interruptions and non-adherence with imatinib and associated healthcare costs: A retrospective analysis among managed care patients with chronic myelogenous leukaemia
    • Darkow T, Henk HJ, Thomas SK, Feng W, Baladi JF, Goldberg GA, et al. Treatment interruptions and non-adherence with imatinib and associated healthcare costs: a retrospective analysis among managed care patients with chronic myelogenous leukaemia. Pharmacoeconomics. 2007; 25(6):481-96.
    • (2007) Pharmacoeconomics , vol.25 , Issue.6 , pp. 481-496
    • Darkow, T.1    Henk, H.J.2    Thomas, S.K.3    Feng, W.4    Baladi, J.F.5    Goldberg, G.A.6
  • 21
    • 79954585749 scopus 로고    scopus 로고
    • Exploring chronic myeloid leukemia patients' reasons for not adhering to the oral anticancer drug imatinib as prescribed
    • Eliasson L, Clifford S, Barber N, Marin D. Exploring chronic myeloid leukemia patients' reasons for not adhering to the oral anticancer drug imatinib as prescribed. Leuk Res. 2011;35(5):626-30.
    • (2011) Leuk Res , vol.35 , Issue.5 , pp. 626-630
    • Eliasson, L.1    Clifford, S.2    Barber, N.3    Marin, D.4
  • 22
    • 79960958281 scopus 로고    scopus 로고
    • Nonadherence to imatinib adversely affects event free survival in chronic phase chronic myeloid leukemia
    • Ganesan P, Sagar TG, Dubashi B, Rajendranath R, Kannan K, Cyriac S, et al. Nonadherence to imatinib adversely affects event free survival in chronic phase chronic myeloid leukemia. Am J Hematol. 2011;86(6):471-4.
    • (2011) Am J Hematol , vol.86 , Issue.6 , pp. 471-474
    • Ganesan, P.1    Sagar, T.G.2    Dubashi, B.3    Rajendranath, R.4    Kannan, K.5    Cyriac, S.6
  • 23
    • 67650485799 scopus 로고    scopus 로고
    • Costs and utilization associated with imatinib adherence in patients with chronic myeloid leukemia or gastrointestinal stromal tumors
    • Halpern R, Barghout V, Zarotsky V, Williams D. Costs and utilization associated with imatinib adherence in patients with chronic myeloid leukemia or gastrointestinal stromal tumors. J Clin Outcomes Manag. 2009;16(5):215-23.
    • (2009) J Clin Outcomes Manag , vol.16 , Issue.5 , pp. 215-223
    • Halpern, R.1    Barghout, V.2    Zarotsky, V.3    Williams, D.4
  • 24
    • 79953823237 scopus 로고    scopus 로고
    • Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy
    • Ibrahim AR, Eliasson L, Apperley JF, Milojkovic D, Bua M, Szydlo R, et al. Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy. Blood. 2011;117(14):3733-6.
    • (2011) Blood , vol.117 , Issue.14 , pp. 3733-3736
    • Ibrahim, A.R.1    Eliasson, L.2    Apperley, J.F.3    Milojkovic, D.4    Bua, M.5    Szydlo, R.6
  • 25
    • 84861441763 scopus 로고    scopus 로고
    • Good adherence to imatinib therapy among patients with chronic myeloid leukemia-a single-center observational study
    • Jönsson S, Olsson B, Söderberg J, Wadenvik H. Good adherence to imatinib therapy among patients with chronic myeloid leukemia-a single-center observational study. Ann Hematol. 2012;91(5):679-85.
    • (2012) Ann Hematol , vol.91 , Issue.5 , pp. 679-685
    • Jönsson, S.1    Olsson, B.2    Söderberg, J.3    Wadenvik, H.4
  • 26
    • 58549109605 scopus 로고    scopus 로고
    • Compliance with taking imatinib mesylate in patients with chronic myeloid leukemia in the chronic phase
    • Kiguchi T, Tauchi T, Ito Y, Miyazawa K, Kimura Y, Ohyashiki K. Compliance with taking imatinib mesylate in patients with chronic myeloid leukemia in the chronic phase. Leuk Res. 2009;33(3):506-8.
    • (2009) Leuk Res , vol.33 , Issue.3 , pp. 506-508
    • Kiguchi, T.1    Tauchi, T.2    Ito, Y.3    Miyazawa, K.4    Kimura, Y.5    Ohyashiki, K.6
  • 27
    • 33746153427 scopus 로고    scopus 로고
    • Factors influencing adherence to molecular therapies in haematology-oncology outpatients
    • Kong DC, Dooley MJ, Stewart K, Larizza MA. Factors influencing adherence to molecular therapies in haematology-oncology outpatients. J Pharm Prac Res. 2006; 36(2):115-8.
    • (2006) J Pharm Prac Res , vol.36 , Issue.2 , pp. 115-118
    • Kong, D.C.1    Dooley, M.J.2    Stewart, K.3    Larizza, M.A.4
  • 28
    • 84866279866 scopus 로고    scopus 로고
    • Patient counseling program to improve the compliance to imatinib in chronic myeloid leukemia patients
    • Moon JH, Sohn SK, Kim SN, Park SY, Yoon SS, Kim IH, et al. Patient counseling program to improve the compliance to imatinib in chronic myeloid leukemia patients. Med Oncol. 2012;29(2):1179-85.
    • (2012) Med Oncol , vol.29 , Issue.2 , pp. 1179-1185
    • Moon, J.H.1    Sohn, S.K.2    Kim, S.N.3    Park, S.Y.4    Yoon, S.S.5    Kim, I.H.6
  • 29
    • 79952251630 scopus 로고    scopus 로고
    • Excellent outcomes of children with CML treated with imatinib mesylate compared to that in pre-imatinib era
    • Muramatsu H, Takahashi Y, Sakaguchi H, Shimada A, Nishio N, Hama A, et al. Excellent outcomes of children with CML treated with imatinib mesylate compared to that in pre-imatinib era. Int J Hematol. 2011;93(2):186-91.
    • (2011) Int J Hematol , vol.93 , Issue.2 , pp. 186-191
    • Muramatsu, H.1    Takahashi, Y.2    Sakaguchi, H.3    Shimada, A.4    Nishio, N.5    Hama, A.6
  • 30
    • 79952635492 scopus 로고    scopus 로고
    • Compliance during therapy of patients with chronic myeloid leukemia
    • Prejzner W. Compliance during therapy of patients with chronic myeloid leukemia. Hematologica. 2010;1(3):239-43.
    • (2010) Hematologica , vol.1 , Issue.3 , pp. 239-243
    • Prejzner, W.1
  • 31
    • 78349255323 scopus 로고    scopus 로고
    • Retrospective real-world comparison of medical visits, costs, and adherence between nilotinib and dasatinib in chronic myeloid leukemia
    • Wu EQ, Guerin A, Yu AP, Bollu VK, Guo A, Griffin JD. Retrospective real-world comparison of medical visits, costs, and adherence between nilotinib and dasatinib in chronic myeloid leukemia. Curr Med Res Opin. 2010;26(12):2861-9.
    • (2010) Curr Med Res Opin , vol.26 , Issue.12 , pp. 2861-2869
    • Wu, E.Q.1    Guerin, A.2    Yu, A.P.3    Bollu, V.K.4    Guo, A.5    Griffin, J.D.6
  • 32
    • 77649221871 scopus 로고    scopus 로고
    • Healthcare resource utilization and costs associated with nonadherence to imatinib treatment in chronic myeloid leukemia patients
    • Wu EQ, Johnson S, Beaulieu N, Arana M, Bollu V, Guo A, et al. Healthcare resource utilization and costs associated with nonadherence to imatinib treatment in chronic myeloid leukemia patients. Curr Med Res Opin. 2010;26(1):61-9.
    • (2010) Curr Med Res Opin , vol.26 , Issue.1 , pp. 61-69
    • Wu, E.Q.1    Johnson, S.2    Beaulieu, N.3    Arana, M.4    Bollu, V.5    Guo, A.6
  • 33
    • 84856433004 scopus 로고    scopus 로고
    • Adherence to treatment with second-line therapies, dasatinib and nilotinib, in patients with chronic myeloid leukemia
    • Yood MU, Oliveria SA, Cziraky M, Hirji I, Hamdan M, Davis C. Adherence to treatment with second-line therapies, dasatinib and nilotinib, in patients with chronic myeloid leukemia. Curr Med Res Opin. 2012;28(2):213-9.
    • (2012) Curr Med Res Opin , vol.28 , Issue.2 , pp. 213-219
    • Yood, M.U.1    Oliveria, S.A.2    Cziraky, M.3    Hirji, I.4    Hamdan, M.5    Davis, C.6
  • 34
    • 84856449120 scopus 로고    scopus 로고
    • Adherence to treatment in patients with chronic myelogenous leukemia (CML) during a 10-year time period: A medical record review
    • Abstract 4492
    • Yood MU, Oliveria SA, Hirji I, Cziraky M, Davis C. Adherence to treatment in patients with chronic myelogenous leukemia (CML) during a 10-year time period: a medical record review. Blood. 2010;116(21):Abstract 4492.
    • (2010) Blood , vol.116 , Issue.21
    • Yood, M.U.1    Oliveria, S.A.2    Hirji, I.3    Cziraky, M.4    Davis, C.5
  • 35
    • 80052873243 scopus 로고    scopus 로고
    • Adherence to the standard dose of imatinib, rather than dose adjustment based on its plasma concentration, is critical to achieve a deep molecular response in patients with chronic myeloid leukemia
    • Yoshida C, Komeno T, Hori M, Kimura T, Fujii M, Okoshi Y, et al. Adherence to the standard dose of imatinib, rather than dose adjustment based on its plasma concentration, is critical to achieve a deep molecular response in patients with chronic myeloid leukemia. Int J Hematol. 2011;93(5):618-23.
    • (2011) Int J Hematol , vol.93 , Issue.5 , pp. 618-623
    • Yoshida, C.1    Komeno, T.2    Hori, M.3    Kimura, T.4    Fujii, M.5    Okoshi, Y.6
  • 36
    • 84862311641 scopus 로고    scopus 로고
    • High adherence to Tyrosine Kinase Inhibitors seems to be related to best cytogenetic response in the hasford lower risk group in Chronic Myeloid Leukemia
    • Abstract 4477
    • Almeida M, Pagnano K, Souza H, Miranda E, De Souza C. High adherence to Tyrosine Kinase Inhibitors seems to be related to best cytogenetic response in the hasford lower risk group in Chronic Myeloid Leukemia. Blood. 2010;116(21):Abstract 4477.
    • (2010) Blood , vol.116 , Issue.21
    • Almeida, M.1    Pagnano, K.2    Souza, H.3    Miranda, E.4    De Souza, C.5
  • 37
    • 84895766065 scopus 로고    scopus 로고
    • Higher adherence related to complete molecular response (CMR) in chronic myeloid leukemia patients using imatinib mesilate
    • Abstract 678
    • Almeida MH, Pagnano KB, Miranda EC, Souza CA. Higher adherence related to complete molecular response (CMR) in chronic myeloid leukemia patients using imatinib mesilate. Haematologica. 2011;96(suppl. 2):Abstract 678.
    • (2011) Haematologica , vol.96 , Issue.SUPPL. 2
    • Almeida, M.H.1    Pagnano, K.B.2    Miranda, E.C.3    Souza, C.A.4
  • 38
    • 84857521889 scopus 로고    scopus 로고
    • Adherence to tyrosine kinase inhibitors (TKI) in chronic myeloid leukemia (CML) seems to be related to duration of treatment and type of TKI
    • Abstract 820
    • Almeida MH, Barbosa Pagnano KB, Sanges Souza HA, Souza CA. Adherence to tyrosine kinase inhibitors (TKI) in chronic myeloid leukemia (CML) seems to be related to duration of treatment and type of TKI. Haematologica. 2010;95(suppl. 2): Abstract 820.
    • (2010) Haematologica , vol.95 , Issue.SUPPL. 2
    • Almeida, M.H.1    Barbosa Pagnano, K.B.2    Sanges Souza, H.A.3    Souza, C.A.4
  • 39
    • 84857593539 scopus 로고    scopus 로고
    • Adherence assessment in Chronic Myeloid Leukaemia patients treated by tyrosine kinase inhibitors
    • Daouphars M, Ouvry M, Lenain P, Rouvet J, Varin R. Adherence assessment in Chronic Myeloid Leukaemia patients treated by tyrosine kinase inhibitors. Int J Clin Pharm. 2011;33:414-15.
    • (2011) Int J Clin Pharm , vol.33 , pp. 414-415
    • Daouphars, M.1    Ouvry, M.2    Lenain, P.3    Rouvet, J.4    Varin, R.5
  • 41
    • 84862311620 scopus 로고    scopus 로고
    • Impact of comorbidity in event-free survival, toxicity and adherence to treatment in chronic myeloid leukemia patients treated with imatinib
    • Abstract 2296
    • Fogliatto L, Capra M, Schaan M, Fassina K, Fernandes MS, Schilling MA, et al. Impact of comorbidity in event-free survival, toxicity and adherence to treatment in chronic myeloid leukemia patients treated with imatinib. Blood. 2010;116(21):Abstract 2296.
    • (2010) Blood , vol.116 , Issue.21
    • Fogliatto, L.1    Capra, M.2    Schaan, M.3    Fassina, K.4    Fernandes, M.S.5    Schilling, M.A.6
  • 42
    • 84895757027 scopus 로고    scopus 로고
    • Impact of non-adherence to Imatinib on progressionfree survival a 1st treatment for Chronic Myeloid Leukemia in Brazil: Two years follow up
    • Funke VAM, Moellmann-Coelho A, Asano E, Nita ME, Donato BM, Rahal E. Impact of non-adherence to Imatinib on progressionfree survival a 1st treatment for Chronic Myeloid Leukemia in Brazil: two years follow up. Value Health. 2011;14(3):A168-9.
    • (2011) Value Health , vol.14 , Issue.3
    • Funke, V.A.M.1    Moellmann-Coelho, A.2    Asano, E.3    Nita, M.E.4    Donato, B.M.5    Rahal, E.6
  • 43
    • 84895740275 scopus 로고    scopus 로고
    • Associations between treatment restrictions, patientreported treatment burden and adherence to tyrosine-kinase inhibitor therapy among Chronic Myeloid Leukemia patients in the United States and Europe
    • Abstract 2077
    • Gupta S, Goren A, Victor TW, Chapnick J, Hawthorne S, Hirji I, et al. Associations between treatment restrictions, patientreported treatment burden and adherence to tyrosine-kinase inhibitor therapy among Chronic Myeloid Leukemia patients in the United States and Europe. Blood. 2011;118 (21):Abstract 2077.
    • (2011) Blood , vol.118 , Issue.21
    • Gupta, S.1    Goren, A.2    Victor, T.W.3    Chapnick, J.4    Hawthorne, S.5    Hirji, I.6
  • 44
    • 84855779920 scopus 로고    scopus 로고
    • A global retrospective and physician-based analysis of adherence to tyrosine kinase inhibitor (TKI) therapies for chronic myeloid leukemia (CML)
    • Abstract 1514
    • Guilhot F, Coombs J, Zernovak O, Szczudlo T, Rosti G. A global retrospective and physician-based analysis of adherence to tyrosine kinase inhibitor (TKI) therapies for chronic myeloid leukemia (CML). Blood. 2010;116(21):Abstract 1514.
    • (2010) Blood , vol.116 , Issue.21
    • Guilhot, F.1    Coombs, J.2    Zernovak, O.3    Szczudlo, T.4    Rosti, G.5
  • 46
    • 84862311380 scopus 로고    scopus 로고
    • Disease knowledge in chronic myeloid leukemia (CML) patients as a predictor of compliance to treatment
    • Abstract 4481
    • Johnson CN, Cowan L, Gorospe GL, Ailawadhi S. Disease knowledge in chronic myeloid leukemia (CML) patients as a predictor of compliance to treatment. Blood. 2010;116(21):Abstract 4481.
    • (2010) Blood , vol.116 , Issue.21
    • Johnson, C.N.1    Cowan, L.2    Gorospe, G.L.3    Ailawadhi, S.4
  • 47
    • 84895770769 scopus 로고    scopus 로고
    • Imatinib trough plasma levels in Philadelphia positive chronic myeloid leukemia (CML) patients: Results of a multicenter study CSTI571AIL11TGLIVEC
    • Abstract 0809
    • Koren-Michowitz M, Volchek Y, Ben-Yehuda D, Naparstek E, Gavish I, Levi E, et al. Imatinib trough plasma levels in Philadelphia positive chronic myeloid leukemia (CML) patients: results of a multicenter study CSTI571AIL11TGLIVEC. Hematologica. 2010;95(suppl. 2):Abstract 0809.
    • (2010) Hematologica , vol.95 , Issue.SUPPL. 2
    • Koren-Michowitz, M.1    Volchek, Y.2    Ben-Yehuda, D.3    Naparstek, E.4    Gavish, I.5    Levi, E.6
  • 48
    • 84895731465 scopus 로고    scopus 로고
    • The role of imatinib plasma level test in evaluation of the nonadherence to therapy in chronic myelogenous leukemia patients
    • Abstract 0817
    • Kutsev S, Oxenjuk O, Kravchenko E, Shatokhin Y, Bogdanova Y, Burnasheva E, et al. The role of imatinib plasma level test in evaluation of the nonadherence to therapy in chronic myelogenous leukemia patients. Hematologica. 2010;95(suppl. 2):Abstract 0817.
    • (2010) Hematologica , vol.95 , Issue.SUPPL. 2
    • Kutsev, S.1    Oxenjuk, O.2    Kravchenko, E.3    Shatokhin, Y.4    Bogdanova, Y.5    Burnasheva, E.6
  • 49
    • 84857535432 scopus 로고    scopus 로고
    • Imatinib meslylate plasma levels predict compliance in patients with chronic myelogenous leukemia
    • Abstract 4274
    • Lee S, Johnson C, Sandoval Y, Gorospe G, Yang AS, Ailawadhi S. Imatinib meslylate plasma levels predict compliance in patients with chronic myelogenous leukemia. Blood. 2009;114(22):Abstract 4274.
    • (2009) Blood , vol.114 , Issue.22
    • Lee, S.1    Johnson, C.2    Sandoval, Y.3    Gorospe, G.4    Yang, A.S.5    Ailawadhi, S.6
  • 50
    • 77950435478 scopus 로고    scopus 로고
    • The combination of interferon-alpha with imatinib in early chronic phase chronic myeloid leukemia patients induces a significant improvement of the molecular responses in the first two years of treatment: Results from three studies from the GIMEMA CML Working Party
    • Abstract 2192
    • Palandri F, Castagnetti F, Iacobucci I, Amabile M, Gugliotta G, Poerio A, et al. The combination of interferon-alpha with imatinib in early chronic phase chronic myeloid leukemia patients induces a significant improvement of the molecular responses in the first two years of treatment: results from three studies from the GIMEMA CML Working Party. Blood. 2009;114(22):Abstract 2192.
    • (2009) Blood , vol.114 , Issue.22
    • Palandri, F.1    Castagnetti, F.2    Iacobucci, I.3    Amabile, M.4    Gugliotta, G.5    Poerio, A.6
  • 51
    • 67349248447 scopus 로고    scopus 로고
    • High and early rates of cytogenetic and molecular response with nilotinib 800 mg daily as first line treatment of Ph-positive chronic myeloid leukemia in chronic phase: Results of a phase 2 trial of the GIMEMA CML Working Party
    • Abstract 181
    • Rosti G, Castagnetti F, Poerio A, Breccia M, Levato L, Capucci A, et al. High and early rates of cytogenetic and molecular response with nilotinib 800 mg daily as first line treatment of Ph-positive chronic myeloid leukemia in chronic phase: results of a phase 2 trial of the GIMEMA CML Working Party. Blood. 2008;112(11): Abstract 181.
    • (2008) Blood , vol.112 , Issue.11
    • Rosti, G.1    Castagnetti, F.2    Poerio, A.3    Breccia, M.4    Levato, L.5    Capucci, A.6
  • 52
    • 78649635342 scopus 로고    scopus 로고
    • Predictors of treatment non-adherence in patients treated with imatinib mesylate for chronic myeloid leukemia
    • Abstract 2209
    • St Charles M, Bollu VK, Hornyak E, Coombs J, Blanchette CM, DeAngelo DJ. Predictors of treatment non-adherence in patients treated with imatinib mesylate for chronic myeloid leukemia. Blood. 2009;114(22):Abstract 2209.
    • (2009) Blood , vol.114 , Issue.22
    • St Charles, M.1    Bollu, V.K.2    Hornyak, E.3    Coombs, J.4    Blanchette, C.M.5    DeAngelo, D.J.6
  • 53
    • 84895770203 scopus 로고    scopus 로고
    • Impact of pleural effusion (PE) on treatment adherence, discontinuation, switching, and dose modification in patients with chronic myelogenous leukemia (CML)
    • Abstract 6616
    • Wu EQ, Guerin A, Bollu VK, Guo A, Cloutier M, Ponce de Leon Barido D, et al. Impact of pleural effusion (PE) on treatment adherence, discontinuation, switching, and dose modification in patients with chronic myelogenous leukemia (CML). J Clin Oncol. 2011;29(suppl.):Abstract 6616.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Wu, E.Q.1    Guerin, A.2    Bollu, V.K.3    Guo, A.4    Cloutier, M.5    Ponce de Leon Barido, D.6
  • 54
    • 84895758934 scopus 로고    scopus 로고
    • What doctors don't know about adherence: A qualitative study of adherence to imatinib amongst patients with chronic myeloid leukaemia
    • Abstract P1-127
    • Wu S, Chee D, Ugalde A, Butow P, Seymour J, Schofield P. What doctors don't know about adherence: a qualitative study of adherence to imatinib amongst patients with chronic myeloid leukaemia. Psychooncology. 2011;20(suppl. 2):Abstract P1-127.
    • (2011) Psychooncology , vol.20 , Issue.SUPPL. 2
    • Wu, S.1    Chee, D.2    Ugalde, A.3    Butow, P.4    Seymour, J.5    Schofield, P.6
  • 55
    • 38449115203 scopus 로고    scopus 로고
    • Reporting of adherence to medication in recent randomized controlled trials of 6 chronic diseases: A systematic literature review
    • Gossec L, Tubach F, Dougados M, Ravaud P. Reporting of adherence to medication in recent randomized controlled trials of 6 chronic diseases: a systematic literature review. Am J Med Sci. 2007;334(4):248-54.
    • (2007) Am J Med Sci , vol.334 , Issue.4 , pp. 248-254
    • Gossec, L.1    Tubach, F.2    Dougados, M.3    Ravaud, P.4
  • 56
    • 0001939731 scopus 로고
    • Conceptual and methodological problems in measuring compliance
    • In: Haynes RB, Taylor DW, Sackett DL, eds, Baltimore, MD: Johns Hopkins University Press
    • Gordis L. Conceptual and methodological problems in measuring compliance. In: Haynes RB, Taylor DW, Sackett DL, eds. Compliance in Health Care. Baltimore, MD: Johns Hopkins University Press. 1979;23-5.
    • (1979) Compliance in Health Care , pp. 23-25
    • Gordis, L.1
  • 58
    • 0027322150 scopus 로고
    • The rational clinical examination. Is the patient taking the treatment as prescribed?
    • Stephenson BJ, Rowe BH, Haynes RB, Macharia WM, Leon G. The rational clinical examination. Is the patient taking the treatment as prescribed? JAMA. 1993;269(21):2779-81.
    • (1993) JAMA , vol.269 , Issue.21 , pp. 2779-2781
    • Stephenson, B.J.1    Rowe, B.H.2    Haynes, R.B.3    McHaria, W.M.4    Leon, G.5
  • 61
    • 84870931711 scopus 로고    scopus 로고
    • Imatinib plasma trough levels in chronic myeloid leukaemia: Results of a multicentre study CSTI571AIL11TGLIVEC
    • Koren-Michowitz M, Volchek Y, Naparstek E, Gavish I, Levi I, Rowe JM, et al. Imatinib plasma trough levels in chronic myeloid leukaemia: results of a multicentre study CSTI571AIL11TGLIVEC. Hematol Oncol. 2012;30(4):200-5.
    • (2012) Hematol Oncol , vol.30 , Issue.4 , pp. 200-205
    • Koren-Michowitz, M.1    Volchek, Y.2    Naparstek, E.3    Gavish, I.4    Levi, I.5    Rowe, J.M.6
  • 62
    • 84879064661 scopus 로고    scopus 로고
    • Determination of serum levels of imatinib mesylate in patients with chronic myeloid leukemia: Validation and application of a new analytical method to monitor treatment compliance
    • Rezende VM, Rivellis AJ, Gomes MM, Dörr FA, Novaes MM, Nardinelli L, et al. Determination of serum levels of imatinib mesylate in patients with chronic myeloid leukemia: validation and application of a new analytical method to monitor treatment compliance. Rev Bras Hematol Hemoter. 2013;35(2):103-8.
    • (2013) Rev Bras Hematol Hemoter , vol.35 , Issue.2 , pp. 103-108
    • Rezende, V.M.1    Rivellis, A.J.2    Gomes, M.M.3    Dörr, F.A.4    Novaes, M.M.5    Nardinelli, L.6
  • 63
    • 84875415478 scopus 로고    scopus 로고
    • Preliminary validation of self-assessment tool to measure imatinib adherence in patients with chronic myeloid leukemia
    • Daouphars M, Ouvry M, Lenain P, Rouvet J, Jardin F, Bubenheim M, et al. Preliminary validation of self-assessment tool to measure imatinib adherence in patients with chronic myeloid leukemia. Pharmacotherapy. 2013;33(2):152-6.
    • (2013) Pharmacotherapy , vol.33 , Issue.2 , pp. 152-156
    • Daouphars, M.1    Ouvry, M.2    Lenain, P.3    Rouvet, J.4    Jardin, F.5    Bubenheim, M.6
  • 64
    • 16844368156 scopus 로고    scopus 로고
    • Successful projection of the time course of drug concentration in plasma during a 1-year period from electronically compiled dosing-time data used as input to individually parameterized pharmacokinetic models
    • Vrijens B, Tousset E, Rode R, Bertz R, Mayer S, Urquhart J. Successful projection of the time course of drug concentration in plasma during a 1-year period from electronically compiled dosing-time data used as input to individually parameterized pharmacokinetic models. J Clin Pharmacol. 2005;45(4):461-7.
    • (2005) J Clin Pharmacol , vol.45 , Issue.4 , pp. 461-467
    • Vrijens, B.1    Tousset, E.2    Rode, R.3    Bertz, R.4    Mayer, S.5    Urquhart, J.6
  • 65
    • 84878291260 scopus 로고    scopus 로고
    • Identification and assessment of adherence-enhancing interventions in studies assessing medication adherence through electronically compiled drug dosing histories: A systematic literature review and meta-analysis
    • Demonceau J, Ruppar T, Kristanto P, Hughes DA, Fargher E, Kardas P, et al. Identification and assessment of adherence-enhancing interventions in studies assessing medication adherence through electronically compiled drug dosing histories: a systematic literature review and meta-analysis. Drugs. 2013;73(6):545-62.
    • (2013) Drugs , vol.73 , Issue.6 , pp. 545-562
    • Demonceau, J.1    Ruppar, T.2    Kristanto, P.3    Hughes, D.A.4    Fargher, E.5    Kardas, P.6
  • 66
    • 84863618702 scopus 로고    scopus 로고
    • A retrospective analysis of therapy adherence in imatinib resistant or intolerant patients with chronic myeloid leukemia receiving nilotinib or dasatinib in a real-world setting
    • Guérin A, Chen L, Wu EQ, de Leon DP, Griffin JD. A retrospective analysis of therapy adherence in imatinib resistant or intolerant patients with chronic myeloid leukemia receiving nilotinib or dasatinib in a real-world setting. Curr Med Res Opin. 2012;28(7):1155-62.
    • (2012) Curr Med Res Opin , vol.28 , Issue.7 , pp. 1155-1162
    • Guérin, A.1    Chen, L.2    Wu, E.Q.3    de Leon, D.P.4    Griffin, J.D.5
  • 67
    • 84874250787 scopus 로고    scopus 로고
    • Patient adherence and persistence with Imatinib, Nilotinib, Dasatinib in clinical practice
    • Santoleri F, Sorice P, Lasala R, Rizzo RC, Costantini A. Patient adherence and persistence with Imatinib, Nilotinib, Dasatinib in clinical practice. PLoS One. 2013;8(2): e56813.
    • (2013) PLoS One , vol.8 , Issue.2
    • Santoleri, F.1    Sorice, P.2    Lasala, R.3    Rizzo, R.C.4    Costantini, A.5
  • 68
    • 0035477744 scopus 로고    scopus 로고
    • Antiretroviral regimen complexity, selfreported adherence, and HIV patients' understanding of their regimens: Survey of women in the her study
    • Stone VE, Hogan JW, Schuman P, Rompalo AM, Howard AA, Korkontzelou C, et al. Antiretroviral regimen complexity, selfreported adherence, and HIV patients' understanding of their regimens: survey of women in the her study. J Acquir Immune Defic Syndr. 2001;28(2):124-31.
    • (2001) J Acquir Immune Defic Syndr , vol.28 , Issue.2 , pp. 124-131
    • Stone, V.E.1    Hogan, J.W.2    Schuman, P.3    Rompalo, A.M.4    Howard, A.A.5    Korkontzelou, C.6
  • 69
    • 84857529579 scopus 로고    scopus 로고
    • Adherence to antiretroviral treatment and correlation with risk of hospitalization among commercially insured HIV patients in the United States
    • Sax PE, Meyers JL, Mugavero M, Davis KL. Adherence to antiretroviral treatment and correlation with risk of hospitalization among commercially insured HIV patients in the United States. PLoS One. 2012;7(2): e31591.
    • (2012) PLoS One , vol.7 , Issue.2
    • Sax, P.E.1    Meyers, J.L.2    Mugavero, M.3    Davis, K.L.4
  • 71
    • 0036193014 scopus 로고    scopus 로고
    • Relationship between daily dose frequency and adherence to antihypertensive pharmacotherapy: Evidence from a meta-analysis
    • Iskedjian M, Einarson TR, MacKeigan LD, Shear N, Addis A, Mittmann N, et al. Relationship between daily dose frequency and adherence to antihypertensive pharmacotherapy: evidence from a meta-analysis. Clin Ther. 2002;24(2):302-16.
    • (2002) Clin Ther , vol.24 , Issue.2 , pp. 302-316
    • Iskedjian, M.1    Einarson, T.R.2    McKeigan, L.D.3    Shear, N.4    Addis, A.5    Mittmann, N.6
  • 72
    • 34447116915 scopus 로고    scopus 로고
    • Estimation of the comparative therapeutic superiority of QD and BID dosing regimens, based on integrated analysis of dosing history data and pharmacokinetics
    • Comté L, Vrijens B, Tousset E, Gérard P, Urquhart J. Estimation of the comparative therapeutic superiority of QD and BID dosing regimens, based on integrated analysis of dosing history data and pharmacokinetics. J Pharmacokinet Pharmacodyn. 2007;34(4):549-58.
    • (2007) J Pharmacokinet Pharmacodyn , vol.34 , Issue.4 , pp. 549-558
    • Comté, L.1    Vrijens, B.2    Tousset, E.3    Gérard, P.4    Urquhart, J.5
  • 73
    • 84886314878 scopus 로고    scopus 로고
    • Prospective evaluation of perceived barriers to medication adherence by patients on oral antineoplastics
    • Abstract 6042
    • Muluneh B, Alexander M, Deal AM, Deal M, Markey J, Neal J, et al. Prospective evaluation of perceived barriers to medication adherence by patients on oral antineoplastics. J Clin Oncol. 2012;30(suppl.):Abstract 6042.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Muluneh, B.1    Alexander, M.2    Deal, A.M.3    Deal, M.4    Markey, J.5    Neal, J.6
  • 74
    • 84865860300 scopus 로고    scopus 로고
    • Investigating factors associated with adherence behaviour in patients with chronic myeloid leukemia: An observational patient-centered outcome study
    • Efficace F, Baccarani M, Rosti G, Cottone F, Castagnetti F, Breccia M, et al. Investigating factors associated with adherence behaviour in patients with chronic myeloid leukemia: an observational patient-centered outcome study. Br J Cancer. 2012; 107(6):904-9.
    • (2012) Br J Cancer , vol.107 , Issue.6 , pp. 904-909
    • Efficace, F.1    Baccarani, M.2    Rosti, G.3    Cottone, F.4    Castagnetti, F.5    Breccia, M.6
  • 75
    • 84895741718 scopus 로고    scopus 로고
    • No margin for nonadherence: Novel application of Kaplan-Meier methods to model the efficacy of adherence to imatinib treatment by patients with chronic myeloid leukemia (the ADAGIO Study)
    • Belgium, October 25-27, Abstract 4
    • Abraham I, Lee C, MacDonald K, van Lierde M-A, Beaver M, Geest SD, et al. No margin for nonadherence: novel application of Kaplan-Meier methods to model the efficacy of adherence to imatinib treatment by patients with chronic myeloid leukemia (the ADAGIO Study). European Society for Patient Adherence, COMpliance, and Persistence Ghent, Belgium, October 25-27, 2012:Abstract 4.
    • (2012) European Society for Patient Adherence, COMpliance, and Persistence Ghent
    • Abraham, I.1    Lee, C.2    McDonald, K.3    van Lierde, M.-A.4    Beaver, M.5    Geest, S.D.6
  • 77
    • 0020082526 scopus 로고
    • The distinction between cost and charges
    • Finkler SA. The distinction between cost and charges. Ann Intern Med. 1982; 96(1):102-9.
    • (1982) Ann Intern Med , vol.96 , Issue.1 , pp. 102-109
    • Finkler, S.A.1
  • 78
    • 20544460816 scopus 로고    scopus 로고
    • Impact of medication adherence on hospitalization risk and healthcare cost
    • Sokol MC, McGuigan KA, Verbrugge RR, Epstein RS. Impact of medication adherence on hospitalization risk and healthcare cost. Med Care. 2005;43(6):521-30.
    • (2005) Med Care , vol.43 , Issue.6 , pp. 521-530
    • Sokol, M.C.1    McGuigan, K.A.2    Verbrugge, R.R.3    Epstein, R.S.4
  • 79
    • 78650875618 scopus 로고    scopus 로고
    • The association of adherence to osteoporosis therapies with fracture, all-cause medical costs, and all-cause hospitalizations: A retrospective claims analysis of female health plan enrollees with osteoporosis
    • Halpern R, Becker L, Iqbal SU, Kazis LE, Macarios D, Badamgarav E. The association of adherence to osteoporosis therapies with fracture, all-cause medical costs, and all-cause hospitalizations: a retrospective claims analysis of female health plan enrollees with osteoporosis. J Manag Care Pharm. 2011;17(1):25-39.
    • (2011) J Manag Care Pharm , vol.17 , Issue.1 , pp. 25-39
    • Halpern, R.1    Becker, L.2    Iqbal, S.U.3    Kazis, L.E.4    McArios, D.5    Badamgarav, E.6
  • 80
    • 78049528573 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
    • Mahon FX, Réa D, Guilhot J, Guilhot F, Huguet F, Nicolini F, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol. 2010;11(11):1029-35.
    • (2010) Lancet Oncol , vol.11 , Issue.11 , pp. 1029-1035
    • Mahon, F.X.1    Réa, D.2    Guilhot, J.3    Guilhot, F.4    Huguet, F.5    Nicolini, F.6
  • 81
    • 84862316946 scopus 로고    scopus 로고
    • Adherence to oral kinase inhibitor therapies in chronic myeloid leukemia
    • Gater A, Heron L, Abetz-Webb L, Coombs J, Simmons J, Guilhot F, et al. Adherence to oral kinase inhibitor therapies in chronic myeloid leukemia. Leuk Res. 2012;36(7): 817-25.
    • (2012) Leuk Res , vol.36 , Issue.7 , pp. 817-825
    • Gater, A.1    Heron, L.2    Abetz-Webb, L.3    Coombs, J.4    Simmons, J.5    Guilhot, F.6
  • 82
    • 84895731429 scopus 로고    scopus 로고
    • Patient's and health professionals' perspectives of adherence and imatinib therapy in treatment of chronic myeloid leukaemia
    • Abstract 305
    • Wu S, Chee D, Ugalde A, Butow P, Seymour J, Schofield P. Patient's and health professionals' perspectives of adherence and imatinib therapy in treatment of chronic myeloid leukaemia. Asia Pac J Clin Oncol. 2011;7(suppl. 4):Abstract 305.
    • (2011) Asia Pac J Clin Oncol , vol.7 , Issue.SUPPL. 4
    • Wu, S.1    Chee, D.2    Ugalde, A.3    Butow, P.4    Seymour, J.5    Schofield, P.6
  • 83
    • 39149145497 scopus 로고    scopus 로고
    • Oral chemotherapy medications: The need for a nurse's touch
    • Winkeljohn DL. Oral chemotherapy medications: the need for a nurse's touch. Clin J Oncol Nurs. 2007;11(6):793-6.
    • (2007) Clin J Oncol Nurs , vol.11 , Issue.6 , pp. 793-796
    • Winkeljohn, D.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.