Microstructure of subretinal drusenoid deposits revealed by adaptive optics imaging

Biomedical Optics Express

Volumn 5, Issue 3, 2014, Pages 713-727

  Meadway, Alexander ^a   Wang, Xiaolin ^a   Curcio, Christine A ^a   Zhang, Yuhua ^a,b,c  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c and Radiation Oncology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEPOSITS; VISION;

AGE-RELATED MACULAR DEGENERATION; FACE STRUCTURE; SCANNING LASER OPHTHALMOSCOPY;

OPTICAL TOMOGRAPHY;

ARTICLE; AUTOFLUORESCENCE; CONTROLLED STUDY; DIODE; DRUSEN; EYE FUNDUS; HUMAN; IMAGE PROCESSING; IMAGING; OPHTHALMIC CAMERA; OPHTHALMOSCOPY; OPTICAL COHERENCE TOMOGRAPHY; OPTICS; PHOTORECEPTOR; RETINA FOVEA; RETINA MACULA AGE RELATED DEGENERATION; SCANNING LASER OPHTHALMOSCOPY; SIGNAL PROCESSING;

EID: 84895744806     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.5.000713     Document Type: Article

References (50)

1. M. Rudolf, G. Malek, J. D. Messinger, M. E. Clark, L. Wang, and C. A. Curcio, "Sub-retinal drusenoid deposits in human retina: organization and composition, " Exp. Eye Res. 87(5), 402-408 (2008).
2. C. A. Curcio, J. D. Messinger, K. R. Sloan, G. McGwin, N. E. Medeiros, and R. F. Spaide, "Subretinal drusenoid deposits in non-neovascular age-related macular degeneration: morphology, prevalence, topography, and biogenesis model, " Retina 33(2), 265-276 (2013).
3. G. Mimoun, G. Soubrane, and G. Coscas, "[Macular drusen], " J. Fr. Ophtalmol. 13(10), 511-530 (1990).
4. J. Sarks, J. Arnold, I. V. Ho, S. Sarks, and M. Killingsworth, "Evolution of reticular pseudodrusen, " Br. J. Ophthalmol. 95(7), 979-985 (2011).
5. S. Y. Cohen, L. Dubois, R. Tadayoni, C. Delahaye-Mazza, C. Debibie, and G. Quentel, "Prevalence of reticular pseudodrusen in age-related macular degeneration with newly diagnosed choroidal neovascularisation, " Br. J. Ophthalmol. 91(3), 354-359 (2007).
6. S. Schmitz-Valckenberg, F. Alten, J. S. Steinberg, G. J. Jaffe, M. Fleckenstein, B. N. Mukesh, T. C. Hohman, and F. G. Holz; Geographic Atrophy Progression (GAP) Study Group, "Reticular drusen associated with geographic atrophy in age-related macular degeneration, " Invest. Ophthalmol. Vis. Sci. 52(9), 5009-5015 (2011).
7. L. Xu, A. M. Blonska, N. M. Pumariega, S. Bearelly, M. A. Sohrab, G. S. Hageman, and R. T. Smith, "Reticular macular disease is associated with multilobular geographic atrophy in age-related macular degeneration, " Retina 33(9), 1850-1862 (2013).
8. M. Marsiglia, S. Boddu, S. Bearelly, L. Xu, B. E. Breaux, Jr., K. B. Freund, L. A. Yannuzzi, and R. T. Smith, "Association between geographic atrophy progression and reticular pseudodrusen in eyes with dry age-related macular degeneration, " Invest. Ophthalmol. Vis. Sci. 54(12), 7362-7369 (2013).
9. R. F. Spaide, "Outer retinal atrophy after regression of subretinal drusenoid deposits as a newly recognized form of late age-related macular degeneration, " Retina 33(9), 1800-1808 (2013).
10. S. A. Zweifel, R. F. Spaide, C. A. Curcio, G. Malek, and Y. Imamura, "Reticular pseudodrusen are subretinal drusenoid deposits, " Ophthalmology 117(2), 303-312 (2010).
11. S. Schmitz-Valckenberg, J. S. Steinberg, M. Fleckenstein, S. Visvalingam, C. K. Brinkmann, and F. G. Holz, "Combined confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography imaging of reticular drusen associated with age-related macular degeneration, " Ophthalmology 117(6), 1169-1176 (2010).
12. G. Querques, M. Srour, N. Massamba, N. Puche, and E. H. Souied, "Reticular pseudodrusen, " Ophthalmology 120(4), 872 (2013).
13. G. Querques, L. Querques, D. Martinelli, N. Massamba, G. Coscas, G. Soubrane, and E. H. Souied, "Pathologic insights from integrated imaging of reticular pseudodrusen in age-related macular degeneration, " Retina 31(3), 518-526 (2011).
14. G. Querques, F. Canouï-Poitrine, F. Coscas, N. Massamba, L. Querques, G. Mimoun, F. Bandello, and E. H. Souied, "Analysis of progression of reticular pseudodrusen by spectral domain-optical coherence tomography, " Invest. Ophthalmol. Vis. Sci. 53(3), 1264-1270 (2012).
15. J. Liang, D. R. Williams, and D. T. Miller, "Supernormal vision and high-resolution retinal imaging through adaptive optics, " J. Opt. Soc. Am. A 14(11), 2884-2892 (1997).
16. A. Roorda, F. Romero-Borja, W. Donnelly III, H. Queener, T. Hebert, and M. Campbell, "Adaptive optics scanning laser ophthalmoscopy, " Opt. Express 10(9), 405-412 (2002).
17. R. J. Zawadzki, S. M. Jones, S. S. Olivier, M. Zhao, B. A. Bower, J. A. Izatt, S. Choi, S. Laut, and J. S. Werner, "Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging, " Opt. Express 13(21), 8532-8546 (2005).
18. Y. Zhang, S. Poonja, and A. Roorda, "MEMS-based adaptive optics scanning laser ophthalmoscopy, " Opt. Lett. 31(9), 1268-1270 (2006).
19. Y. Zhang, S. Poonja, and A. Roorda, "AOSLO: from benchtop to clinic, " Proc. SPIE 6306, 63060V (2006).
20. Y. Zhang, B. Cense, J. Rha, R. S. Jonnal, W. Gao, R. J. Zawadzki, J. S. Werner, S. Jones, S. Olivier, and D. T. Miller, "High-speed volumetric imaging of cone photoreceptors with adaptive optics spectral-domain optical coherence tomography, " Opt. Express 14(10), 4380-4394 (2006).
21. S. A. Burns, R. Tumbar, A. E. Elsner, D. Ferguson, and D. X. Hammer, "Large-field-of-view, modular, stabilized, adaptive-optics-based scanning laser ophthalmoscope, " J. Opt. Soc. Am. A 24(5), 1313-1326 (2007).
22. R. J. Zawadzki, S. S. Choi, S. M. Jones, S. S. Oliver, and J. S. Werner, "Adaptive optics-optical coherence tomography: optimizing visualization of microscopic retinal structures in three dimensions, " J. Opt. Soc. Am. A 24(5), 1373-1383 (2007).
23. R. J. Zawadzki, B. Cense, Y. Zhang, S. S. Choi, D. T. Miller, and J. S. Werner, "Ultrahigh-resolution optical coherence tomography with monochromatic and chromatic aberration correction, " Opt. Express 16(11), 8126-8143 (2008).
24. A. Roorda, "Applications of adaptive optics scanning laser ophthalmoscopy, " Optom. Vis. Sci. 87(4), 260-268 (2010).
25. D. T. Miller, O. P. Kocaoglu, Q. Wang, and S. Lee, "Adaptive optics and the eye (super resolution OCT), " Eye (Lond.) 25(3), 321-330 (2011).
26. A. Dubra, Y. Sulai, J. L. Norris, R. F. Cooper, A. M. Dubis, D. R. Williams, and J. Carroll, "Noninvasive imaging of the human rod photoreceptor mosaic using a confocal adaptive optics scanning ophthalmoscope, " Biomed. Opt. Express 2(7), 1864-1876 (2011).
27. R. J. Zawadzki, S. M. Jones, S. Pilli, S. Balderas-Mata, D. Y. Kim, S. S. Olivier, and J. S. Werner, "Integrated adaptive optics optical coherence tomography and adaptive optics scanning laser ophthalmoscope system for simultaneous cellular resolution in vivo retinal imaging, " Biomed. Opt. Express 2(6), 1674-1686 (2011).
28. D. X. Hammer, R. D. Ferguson, M. Mujat, A. Patel, E. Plumb, N. Iftimia, T. Y. Chui, J. D. Akula, and A. B. Fulton, "Multimodal adaptive optics retinal imager: design and performance, " J. Opt. Soc. Am. A 29(12), 2598-2607 (2012).
29. S. Mrejen, T. Sato, C. A. Curcio, and R. F. Spaide, "Assessing the Cone Photoreceptor Mosaic in Eyes with Pseudodrusen and Soft Drusen In Vivo Using Adaptive Optics Imaging, " Ophthalmology 121(2), 545-551 (2013).
30. Y. Zhang, X. Wang, E. R. Blanco, M. E. Clark, C. D. Witherspoon, R. F. Spaide, C. A. Girkin, C. Owsley, and C. A. Curcio, "Photoreceptor perturbation around subretinal drusenoid deposits revealed by adaptive optics scanning laser ophthalmoscopy, " Am. J. Ophthalmol. (In review).
31. R. F. Spaide, "Questioning optical coherence tomography, " Ophthalmology 119(11), 2203-2204 (2012).
32. R. F. Spaide and C. A. Curcio, "Anatomical correlates to the bands seen in the outer retina by optical coherence tomography: literature review and model, " Retina 31(8), 1609-1619 (2011).
33. A. Meadway, C. A. Girkin, and Y. Zhang, "A dual-modal retinal imaging system with adaptive optics, " Opt. Express 21(24), 29792-29807 (2013).
34. Y. Zhang, J. Rha, R. Jonnal, and D. Miller, "Adaptive optics parallel spectral domain optical coherence tomography for imaging the living retina, " Opt. Express 13(12), 4792-4811 (2005).
35. F. C. Delori, R. H. Webb, and D. H. Sliney; American National Standards Institute, "Maximum permissible exposures for ocular safety (ANSI 2000), with emphasis on ophthalmic devices, " J. Opt. Soc. Am. A 24(5), 1250-1265 (2007).
36. C. R. Vogel, D. W. Arathorn, A. Roorda, and A. Parker, "Retinal motion estimation in adaptive optics scanning laser ophthalmoscopy, " Opt. Express 14(2), 487-497 (2006).
37. R. F. Spaide and C. A. Curcio, "Drusen characterization with multimodal imaging, " Retina 30(9), 1441-1454 (2010).
38. N. Ueda-Arakawa, S. Ooto, A. Tsujikawa, K. Yamashiro, A. Oishi, and N. Yoshimura, "Sensitivity and specificity of detecting reticular pseudodrusen in multimodal imaging in Japanese patients, " Retina 33(3), 490-497 (2013).
39. A. Pallikaris, D. R. Williams, and H. Hofer, "The reflectance of single cones in the living human eye, " Invest. Ophthalmol. Vis. Sci. 44(10), 4580-4592 (2003).
40. R. F. Cooper, A. M. Dubis, A. Pavaskar, J. Rha, A. Dubra, and J. Carroll, "Spatial and temporal variation of rod photoreceptor reflectance in the human retina, " Biomed. Opt. Express 2(9), 2577-2589 (2011).
41. O. P. Kocaoglu, S. Lee, R. S. Jonnal, Q. Wang, A. E. Herde, J. C. Derby, W. Gao, and D. T. Miller, "Imaging cone photoreceptors in three dimensions and in time using ultrahigh resolution optical coherence tomography with adaptive optics, " Biomed. Opt. Express 2(4), 748-763 (2011).
42. M. A. Sohrab, R. T. Smith, H. Salehi-Had, S. R. Sadda, and A. A. Fawzi, "Image registration and multimodal imaging of reticular pseudodrusen, " Invest. Ophthalmol. Vis. Sci. 52(8), 5743-5748 (2011).
43. Y. Zhang, S. Poonja, and A. Roorda, "Adaptive optics scanning laser ophthalmoscope using a micro-electromechanical (MEMS) deformable mirror, " Proc. SPIE 6138, 61380Z (2006).
44. C. A. Curcio, J. B. Presley, C. L. Millican, and N. E. Medeiros, "Basal deposits and drusen in eyes with agerelated maculopathy: evidence for solid lipid particles, " Exp. Eye Res. 80(6), 761-775 (2005).
45. J. D. Huang, J. B. Presley, M. F. Chimento, C. A. Curcio, and M. Johnson, "Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch, " Exp. Eye Res. 85(2), 202-218 (2007).
46. C. A. Curcio, M. Johnson, J.-D. Huang, and M. Rudolf, "Aging, age-related macular degeneration, and the Response-to-Retention of apolipoprotein B-containing lipoproteins, " Prog. Retin. Eye Res. 28(6), 393-422 (2009).
47. R. F. Mullins, L. V. Johnson, D. H. Anderson, and G. S. Hageman, "Characterization of drusen-associated glycoconjugates, " Ophthalmology 104(2), 288-294 (1997).
48. C. M. Li, M. E. Clark, M. Rudolf, and C. A. Curcio, "Distribution and composition of esterified and unesterified cholesterol in extra-macular drusen, " Exp. Eye Res. 85(2), 192-201 (2007).
49. V. Luibl, J. M. Isas, R. Kayed, C. G. Glabe, R. Langen, and J. Chen, "Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers, " J. Clin. Invest. 116(2), 378-385 (2006).
50. S. H. Sarks, D. Van Driel, L. Maxwell, and M. Killingsworth, "Softening of drusen and subretinal neovascularization, " Trans. Ophthalmol. Soc. U. K. 100(3), 414-422 (1980).