New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Nishida, Nao ^a,b   Sawai, Hiromi ^b   Kashiwase, Koichi ^c   Minami, Mutsuhiko ^c   Sugiyama, Masaya ^a   Seto, Wai Kay ^d   Yuen, Man Fung ^d   Posuwan, Nawarat ^e   Poovorawan, Yong ^e   Ahn, Sang Hoon ^f   Han, Kwang Hyub ^f   Matsuura, Kentaro ^g   Tanaka, Yasuhito ^g   Kurosaki, Masayuki ^h   Asahina, Yasuhiro ⁱ   Izumi, Namiki ^h   Kang, Jong Hon ^j   Hige, Shuhei ^k   Yamamoto, Tatsuya Ide Kazuhide ^l,m   Sakaida, Isao ⁿ   Murawaki, Yoshikazu ^o   Itoh, Yoshito ^p   Tamori, Akihiro ^q   Orito, Etsuro ^r   Hiasa, Yoichi ^s   Honda, Masao ^t   Kaneko, Shuichi ^t   Mita, Eiji ^u   Suzuki, Kazuyuki ^v   Hino, Keisuke ^w   Tanaka, Eiji ^x   Mochida, Satoshi ^y   Watanabe, Masaaki ^z   Eguchi, Yuichiro ^aa   Masaki, Naohiko ^a   Murata, Kazumoto ^a   Korenaga, Masaaki ^a   Mawatari, Yoriko ^a   Ohashi, Jun ^ab   Kawashima, Minae ^b   Tokunaga, Katsushi ^b   Mizokami, Masashi ^a   more..

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Japanese Red Cross Kanto Koshinetsu Block Blood Center   (Japan)

^d QUEEN MARY HOSPITAL   (Hong Kong)

^e CHULALONGKORN UNIVERSITY   (Thailand)

^f Yonsei University College of Medicine   (South Korea)

^g NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^h MUSASHINO RED CROSS HOSPITAL   (Japan)

ⁱ TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^j TEINE KEIJINKAI HOSPITAL   (Japan)

^k HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^l KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^m OKAYAMA UNIVERSITY   (Japan)

ⁿ YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^o TOTTORI UNIVERSITY   (Japan)

^p KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^q OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^r NAGOYA DAINI RED CROSS HOSPITAL   (Japan)

^s EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^t KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^u OSAKA NATIONAL HOSPITAL   (Japan)

^v IWATE MEDICAL UNIVERSITY   (Japan)

^w KAWASAKI MEDICAL SCHOOL   (Japan)

^x SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^y SAITAMA MEDICAL UNIVERSITY   (Japan)

^z KITASATO UNIVERSITY   (Japan)

^aa SAGA UNIVERSITY   (Japan)

^ab UNIVERSITY OF TSUKUBA   (Japan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLELE; ARTICLE; ASIAN; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; ETHNICITY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RESISTANCE; GENETIC SUSCEPTIBILITY; GENOTYPING TECHNIQUE; HEPATITIS B; HLA DPA1 GENE; HLA DPB1 GENE; HUMAN; INFECTION RESISTANCE; INFECTION RISK; INFECTION SENSITIVITY; JAPANESE; MAJOR CLINICAL STUDY; MALE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; ASIA; DISEASE RESISTANCE; ETHNIC GROUPS; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HEPATITIS B; HEPATITIS B VIRUS; HLA-DP ANTIGENS; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84895729982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086449     Document Type: Article

References (21)

1. Chen DS (1993) From hepatitis to hepatoma: lessons from type B viral hepatitis. Science 262: 369-370.
2. Custer B, Sullivan SD, Hazlet TK, Iloeje U, Veenstra DL, et al. (2004) Global epidemiology of hepatitis B virus. J Clin Gastroenterol 38: S158-168.
3. Zidan A, Scheuerlein H, Schule S, Settmacher U, Rauchfuss F (2012) Epidemiological pattern of hepatitis B and hepatitis C as etiological agents for hepatocellular carcinoma in iran and worldwide. Hepat Mon 12: e6894.
4. Pungpapong S, Kim WR, Poterucha JJ (2007) Natural history of hepatitis B virus infection: an update for clinicians. Mayo Clin Proc 82: 967-975. (Pubitemid 47206372)
5. Kim DW, Lee SA, Hwang ES, Kook YH, Kim BJ (2012) Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma. PLoS One 7: e47372.
6. Jiang DK, Sun J, Cao G, Liu Y, Lin D, et al. (2013) Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet 45: 72-75.
7. Kamatani Y, Wattanapokayakit S, Ochi H, Kawaguchi T, Takahashi A, et al. (2009) A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Nat Genet 41: 591-595.
8. Mbarek H, Ochi H, Urabe Y, Kumar V, Kubo M, et al. (2011) A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. Hum Mol Genet 20: 3884-3892.
9. Nishida N, Sawai H, Matsuura K, Sugiyama M, Ahn SH, et al. (2012) Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. PLoS One 7: e39175.
10. Guo X, Zhang Y, Li J, Ma J, Wei Z, et al. (2011) Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population. Hepatology 53: 422-428.
11. An P, Winkler C, Guan L, O'Brien SJ, Zeng Z (2011) A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese. J Infect Dis 203: 943-947.
12. Li J, Yang D, He Y, Wang M, Wen Z, et al. (2011) Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. PLoS One 6: e24221.
13. Vermehren J, Lotsch J, Susser S, Wicker S, Berger A, et al. (2012) A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers. PLoS One 7: e32605.
14. Sawai H, Nishida N, Mbarek H, Matsuda K, Mawatari Y, et al. (2012) No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations. BMC Med Genet 13: 47.
15. Chandanayingyong D, Stephens HA, Fan L, Sirikong M, Longta P, et al. (1994) HLA-DPB1 polymorphism in the Thais of Southeast Asia. Hum Immunol 40: 20-24. (Pubitemid 24166516)
16. Chandanayingyong D, Stephens HA, Klaythong R, Sirikong M, Udee S, et al. (1997) HLA-A, -B, -DRB1, -DQA1, and -DQB1 polymorphism in Thais. Hum Immunol 53: 174-182.
17. Maneemaroj R, Stephens HA, Chandanayingyong D, Longta K, Bejrachandra S (1997) HLA class II allele frequencies in northern Thais (Kamphaeng Phet). J Med Assoc Thai 80 Suppl 1: S20-24.
18. Wu TW, Chu CC, Ho TY, Chang Liao HW, Lin SK, et al. (2013) Responses to booster hepatitis B vaccination are significantly correlated with genotypes of human leukocyte antigen (HLA)-DPB1 in neonatally vaccinated adolescents. Hum Genet.
19. Hu L, Zhai X, Liu J, Chu M, Pan S, et al. (2012) Genetic variants in human leukocyte antigen/DP-DQ influence both hepatitis B virus clearance and hepatocellular carcinoma development. Hepatology 55: 1426-1431.
20. Li S, Qian J, Yang Y, Zhao W, Dai J, et al. (2012) GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. PLoS Genet 8: e1002791.
21. StephensM, Smith NJ, Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68: 978-989. (Pubitemid 32289743)