Adjuvant hypofractionated versus conventional whole breast radiation therapy for early-stage breast cancer: Long-term hospital-related morbidity from cardiac causes

International Journal of Radiation Oncology Biology Physics

Volumn 88, Issue 4, 2014, Pages 786-792

  Chan, Elisa K ^a   Woods, Ryan ^b   McBride, Mary L ^b   Virani, Sean ^c   Nichol, Alan ^b   Speers, Caroline ^b   Wai, Elaine S ^b   Tyldesley, Scott ^b  

^a SAINT JOHN REGIONAL HOSPITAL   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; HOSPITALS; RADIOTHERAPY; RISK PERCEPTION;

BREAST RADIATION THERAPY; COMPETING RISKS; CONFIDENCE INTERVAL; EARLY-STAGE BREAST CANCER; HOSPITAL ADMISSIONS; HYPOFRACTIONATED; METHODS AND MATERIALS; POSTOPERATIVE RADIATION THERAPY;

HEART;

ARTICLE; BREAST CANCER; CANCER RADIOTHERAPY; COMORBIDITY; CONVENTIONAL WHOLE BREAST RADIATION THERAPY; EARLY CANCER; FEMALE; FOLLOW UP; HEART INJURY; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; HYPOFRACTIONATED WHOLE BREAST RADIATION THERAPY; LONG TERM CARE; MAJOR CLINICAL STUDY; MASTECTOMY; MORBIDITY; PRIORITY JOURNAL; PROPENSITY SCORE; RANK SUM TEST; THORAX WALL; VERY ELDERLY;

AGED; BREAST; BREAST NEOPLASMS; BRITISH COLUMBIA; DOSE FRACTIONATION; FEMALE; FOLLOW-UP STUDIES; HEART; HOSPITALIZATION; HUMANS; MASTECTOMY; MIDDLE AGED; NEOPLASM STAGING; ORGAN SIZE; ORGANS AT RISK; RADIATION INJURIES; RADIOTHERAPY, ADJUVANT; RISK FACTORS; THORACIC WALL;

EID: 84895729823     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.11.243     Document Type: Article

References (21)

1. M. Clarke, R. Collins, and S. Darby et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials Lancet 366 2005 2087 2106
2. P. McGale, S.C. Darby, and P. Hall et al. Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden Radiother Oncol 100 2011 167 175
3. J.J. Doyle, A.I. Neugut, and J.S. Jacobson et al. Radiation therapy, cardiac risk factors, and cardiac toxicity in early-stage breast cancer patients Int J Radiat Oncol Biol Phys 68 2007 82 93
4. C.W. Taylor, D. Bronnum, and S.C. Darby et al. Cardiac dose estimates from Danish and Swedish breast cancer radiotherapy during 1977-2001 Radiother Oncol 100 2011 176 183
5. S.C. Darby, M. Ewertz, and P. McGale et al. Risk of ischemic heart disease in women after radiotherapy for breast cancer N Engl J Med 368 2013 987 998
6. T.J. Whelan, J.P. Pignol, and M.N. Levine et al. Long-term results of hypofractionated radiation therapy for breast cancer N Engl J Med 362 2010 513 520
7. S.M. Bentzen, R.K. Agrawal, and E.G. Aird et al. The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial Lancet Oncol 9 2008 331 341
8. S.M. Bentzen, R.K. Agrawal, and E.G. Aird et al. The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial Lancet 371 2008 1098 1107
9. B.D. Smith, S.M. Bentzen, and C.R. Correa et al. Fractionation for whole breast irradiation: An American Society for Radiation Oncology (ASTRO) evidence-based guideline Int J Radiat Oncol Biol Phys 81 2011 59 68
10. S.M. Alibhai, M. Duong-Hua, and R. Sutradhar et al. Impact of androgen deprivation therapy on cardiovascular disease and diabetes J Clinl Oncol 27 2009 3452 3458
11. Population Data BC. Available from: http://www.popdata.bc.ca/. Accessed: January 9, 2014.
12. E.L. Stokes, S. Tyldesley, R. Woods, E. Wai, and I.A. Olivotto Effect of nodal irradiation and fraction size on cardiac and cerebrovascular mortality in women with breast cancer treated with local and locoregional radiotherapy Int J Radiat Oncol Biol Phys 80 2011 403 409
13. M.E. Charlson, P. Pompei, and K.L. Ales et al. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation J Chronic Dis 40 1987 373 383
14. World Health Organization International Classification of Diseases: Manual of the International Classification of Diseases, Injuries and Causes of Death. 9th revision 1979 World Health Organization Geneva, Switzerland
15. J.J. Dignam, and M.N. Kocherginsky Choice and interpretation of statistical tests used when competing risks are present J Clinl Oncol 26 2008 4027 4034
16. Chan E, Woods R, Virani S, et al. Long term mortality from cardiac cuses after accelerated hypofractionated versus conventional whole breast radiotherapy for localized left-sided breast cancer. Radiother Oncol 2012;104(S2):S33.
17. E. Tan-Chiu, G. Yothers, and E. Romond et al. Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31 J Clinl Oncol 23 2005 7811 7819
18. E.H. Romond, E.A. Perez, and J. Bryant et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer N Engl J Med 353 2005 1673 1684
19. D.S. Lee, L. Donovan, and P.C. Austin et al. Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes research Med Care 43 2005 182 188
20. R. Chamberlayne, B. Green, and M.L. Barer et al. Creating a population-based linked health database: A new resource for health services research Can J Public Health 89 1998 270 273
21. J.Y.W. Williams Inventory of Studies on the Accuracy of Canadian Health Administrative Databases (Pub No 96-03-TR) 1996 Institute for Clinical Evaluative Sciences Toronto, Canada