Effect of fluoxetine and pergolide on expression of nucleoside transporters and nucleic-related enzymes in mouse brain

Fundamental and Clinical Pharmacology

Volumn 28, Issue 2, 2014, Pages 217-220

  Nagai, Katsuhito ^a   Konishi, Hiroki ^a  

^a OSAKA OHTANI UNIVERSITY   (Japan)

Author keywords

Adenosine; Brain; Fluoxetine; Nucleoside transport system; Pergolide

Indexed keywords

ADENOSINE KINASE; APYRASE; CONCENTRATIVE NUCLEOSIDE TRANSPORTER 2; DOPAMINE RECEPTOR STIMULATING AGENT; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3; FLUOXETINE; MESSENGER RNA; NUCLEOSIDE TRANSPORTER; PERGOLIDE; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOSINE; BRAIN; FLUOXETINE; NUCLEOSIDE TRANSPORT SYSTEM; PERGOLIDE;

ADENOSINE KINASE; ANIMALS; APYRASE; BRAIN; DOPAMINE AGONISTS; FLUOXETINE; MALE; MICE; MICE, INBRED STRAINS; NUCLEOSIDE TRANSPORT PROTEINS; PERGOLIDE; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEROTONIN UPTAKE INHIBITORS;

EID: 84895562240     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/fcp.12011     Document Type: Article

References (9)

1. Boison D. Adenosine as a modulator of brain activity. Drug News Perspect. (2007) 20 607-611.
2. Parkinson F.E., Damaraju V.L., Graham K. et al. Molecular biology of nucleoside transporters and their distributions and functions in the brain. Curr. Top. Med. Chem. (2011) 11 948-972.
3. Latini S., Pedata F. Adenosine in the central nervous system: release mechanisms and extracellular concentrations. J. Neurochem. (2001) 79 463-484.
4. Eltzschig H.K., Weissmuller T., Mager A., Eckle T. Nucleotide metabolism and cell-cell interactions. Methods Mol. Biol. (2006) 341 73-87.
5. Anderson C.M., Bergher J.P., Swanson R.A. ATP-induced ATP release from astrocytes. J. Neurochem. (2004) 88 246-256.
6. Fuxe K., Marcelino D., Borroto-Esuela D.O. et al. Adenosine-dopamine interactions in pathophysiology and treatment of CNS disorders. CNS Neurosci. Ther. (2010) 16 e18-e42.
7. Lesemann A., Reinel C., Huhnchen P. et al. MPTP-induced hippocampal effects on serotonin, dopamine, neurotrophins, adult neurogenesis and depression-like behavior are partially influenced by fluoxetine in adult mice. Brain Res. (2012) Epub ahead of print.
8. Nagai K., Nagasawa K., Fujimoto S. Transport mechanisms for adenosine and uridine in primary-cultured rat cortical neurons and astrocytes. Biochem. Biophys. Res. Commun. (2005) 334 1343-1350.
9. Seppi K., Weintraub D., Coelho M. et al. The movement disorder society evidence-based medicine review update: treatments for the non-motor symptoms of Parkinson's disease. Mov. Disord. (2011) 26 S42-S80.