The potency and efficacy of anticholinergics to inhibit haloperidol-induced catalepsy in rats correlates with their rank order of affinities for the muscarinic receptor subtypes

Neuropharmacology

Volumn 81, Issue , 2014, Pages 176-187

  Erosa Rivero, Helena B ^a   Bata García, José L ^a   Alvarez Cervera, Fernando J ^a   Heredia López, Francisco J ^a   Góngora Alfaro, José L ^a  

^a UNIVERSIDAD AUTÓNOMA DE YUCATÁN   (Mexico)

Author keywords

Acute dystonia; Akathisia; Motor disorders; Parkinsonism; Psychosis; Schizophrenia

Indexed keywords

4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; MUSCARINIC RECEPTOR; OTENZEPAD; PIRENZEPINE; TROPICAMIDE; CHOLINERGIC RECEPTOR BLOCKING AGENT; HALOPERIDOL; NEUROLEPTIC AGENT; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC RECEPTOR BLOCKING; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; CORRELATIONAL STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; EXTRAPYRAMIDAL SYNDROME; HALOPERIDOL-INDUCED CATALEPSY; LATENT PERIOD; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; ANALYSIS OF VARIANCE; ANIMAL; CATALEPSY; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; DRUG INTERACTION; METABOLISM; REACTION TIME; TIME; TOXICITY; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANTIPSYCHOTIC AGENTS; CATALEPSY; CHOLINERGIC ANTAGONISTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HALOPERIDOL; MALE; PIRENZEPINE; PROTEIN BINDING; RATS; RATS, WISTAR; REACTION TIME; RECEPTORS, MUSCARINIC; TIME FACTORS;

EID: 84895554943     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.02.005     Document Type: Article

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